Protein: O45550
Protein Dr1 (Down-regulator of transcription 1) (Negative cofactor 2-beta)

Gene: O45550, dro-1
Organism: Caenorhabditis elegans
Interactions: 20
UniProt ID: O45550

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0016251 - RNA polymerase II general transcription initiation factor activity
GO:0017025 - TBP-class protein binding
GO:0017054 - negative cofactor 2 complex
GO:0046982 - protein heterodimerization activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

234068

O45550
Protein Dr1

1

10

High-throughput

0.656

High

234078

Q86G95
Transcription factor CBF/NF-Y/archaeal histone domain-containing protein

1

20

High-throughput

0.621

High

234073

Q20237
Transcription factor CBF/NF-Y/archaeal histone domain-containing protein

1

20

High-throughput

0.590

High

234071

ZTF2
Zinc finger protein ztf-2

1

1

High-throughput

0.508

High

234074

EGL43
Zinc finger protein egl-43

1

0

High-throughput

0.486

High

112057

OVOLH
Transcription factor ovo-like homolog lin-48

1

2

High-throughput

0.464

High

233715

O45134
X chromosome NonDisjunction factor

1

1

High-throughput

0.464

High

234069

HM09
Homeobox protein ceh-9

1

5

High-throughput

0.464

High

234070

Q18477
Histone deacetylase 11

1

2

High-throughput

0.464

High

234079

Q9N410
BHLH domain-containing protein

1

1

High-throughput

0.464

High

145681

O02174
C3H1-type domain-containing protein

1

3

High-throughput

0.439

High

234080

Q9TXM1
Uncharacterized protein

1

1

High-throughput

0.437

High

115510

H2KZI6
C3H1-type domain-containing protein

1

3

High-throughput

0.417

High

113760

HIF1
Hypoxia-inducible factor 1

1

0

High-throughput

0.265

Low

234072

Q19760
JmjC domain-containing protein

1

0

High-throughput

0.265

Low

234075

TBX9
T-box transcription factor tbx-9

1

0

High-throughput

0.265

Low

234076

LI15A
Protein lin-15A

1

0

High-throughput

0.265

Low

234081

Q9XWJ8
Inhibitor of growth protein

1

0

High-throughput

0.265

Low

234077

EHN3
Zinc finger protein ehn-3

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025