Protein: STA5B
Signal transducer and activator of transcription 5B

Gene: STA5B, STAT5B
Organism: Homo sapiens
Interactions: 98
UniProt ID: P51692

Gene Ontology (top 5):
GO:0000278 - mitotic cell cycle
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

849877

STA5B
Signal transducer and activator of transcription 5B

4

16

Small-scale

0.896

High

786594

STA5A
Signal transducer and activator of transcription 5A

4

16

Small-scale

0.895

High

238387

JAK2
Tyrosine-protein kinase JAK2

3

20

Small-scale

0.835

High

338153

EGFR
Epidermal growth factor receptor

3

20

Small-scale

0.827

High

849903

P55G
Phosphatidylinositol 3-kinase regulatory subunit gamma

2

20

High-throughput

0.783

High

849908

STAC
SH3 and cysteine-rich domain-containing protein

2

5

High-throughput

0.783

High

499250

KIT
Mast/stem cell growth factor receptor Kit

2

13

Small-scale

0.768

High

411341

INSR
Insulin receptor

2

15

Small-scale

0.743

High

337403

ABL1
Tyrosine-protein kinase ABL1

1

14

Small-scale

0.735

High

573623

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

17

Small-scale

0.724

High

616768

JAK1
Tyrosine-protein kinase JAK1

1

20

Small-scale

0.713

High

849884

PTN11
Tyrosine-protein phosphatase non-receptor type 11

1

17

Small-scale

0.692

High

146609

SOCS2
Suppressor of cytokine signaling 2

1

20

High-throughput

0.665

High

500954

GHR
Growth hormone receptor

1

20

Small-scale

0.647

High

849878

JAK3
Tyrosine-protein kinase JAK3

1

20

Small-scale

0.621

High

384522

NTRK1
High affinity nerve growth factor receptor

1

19

High-throughput

0.618

High

601481

FGFR2
Fibroblast growth factor receptor 2

1

19

Small-scale

0.618

High

665833

PTN6
Tyrosine-protein phosphatase non-receptor type 6

1

12

Small-scale

0.618

High

666044

SHC1
SHC-transforming protein 1

1

10

Small-scale

0.618

High

669147

TYK2
Non-receptor tyrosine-protein kinase TYK2

1

20

Small-scale

0.618

High

776615

STAT3
Signal transducer and activator of transcription 3

1

16

Small-scale

0.618

High

786281

STAT1
Signal transducer and activator of transcription 1-alpha/beta

1

16

Small-scale

0.618

High

802809

CRKL
Crk-like protein

1

4

Small-scale

0.618

High

849890

PTK6
Protein-tyrosine kinase 6

1

12

Small-scale

0.618

High

849893

ERBB4
Receptor tyrosine-protein kinase erbB-4

1

20

Small-scale

0.618

High

849898

TRI67
Tripartite motif-containing protein 67

1

10

High-throughput

0.618

High

849911

CISH
Cytokine-inducible SH2-containing protein

1

20

Small-scale

0.618

High

849883

RT06
Small ribosomal subunit protein bS6m

3

1

High-throughput

0.607

High

271058

UBP2
Ubiquitin carboxyl-terminal hydrolase 2

2

7

High-throughput

0.606

High

758158

CDN1A
Cyclin-dependent kinase inhibitor 1

2

1

High-throughput

0.606

High

849881

LMO4
LIM domain transcription factor LMO4

2

3

High-throughput

0.606

High

849887

CAF1A
Chromatin assembly factor 1 subunit A

2

1

High-throughput

0.606

High

540455

IL2RB
Interleukin-2 receptor subunit beta

2

20

Small-scale

0.602

High

581560

VCAM1
Vascular cell adhesion protein 1

2

2

High-throughput

0.601

High

849879

EPHA4
Ephrin type-A receptor 4

1

12

High-throughput

0.590

High

849888

NMI
N-myc-interactor

1

6

Small-scale

0.586

High

849886

RBBP4
Histone-binding protein RBBP4

2

0

High-throughput

0.580

High

849899

MED25
Mediator of RNA polymerase II transcription subunit 25

2

0

High-throughput

0.580

High

849902

PPL13
Placental protein 13-like

2

0

High-throughput

0.580

High

849907

TSSK3
Testis-specific serine/threonine-protein kinase 3

2

0

High-throughput

0.580

High

849885

DDR1
Epithelial discoidin domain-containing receptor 1

1

19

Small-scale

0.575

High

440427

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

2

High-throughput

0.536

High

505797

ODPB
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

1

1

High-throughput

0.536

High

550348

ZEP1
Zinc finger protein 40

1

1

High-throughput

0.536

High

556599

CBR1
Carbonyl reductase [NADPH] 1

1

0

High-throughput

0.518

High

777814

IL15
Interleukin-15

1

0

High-throughput

0.518

High

622410

CCND1
G1/S-specific cyclin-D1

1

5

Small-scale

0.515

High

849643

CCR5
C-C chemokine receptor type 5

1

6

Small-scale

0.515

High

849914

STAP2
Signal-transducing adaptor protein 2

1

1

Small-scale

0.515

High

849900

ZN410
Zinc finger protein 410

1

2

High-throughput

0.515

High

234926

SNX3
Sorting nexin-3

1

0

High-throughput

0.513

High

452688

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

0

High-throughput

0.513

High

829250

SYHM
Histidine--tRNA ligase, mitochondrial

1

0

High-throughput

0.513

High

849892

MVP
Major vault protein

1

0

High-throughput

0.513

High

849910

PUS7L
Pseudouridylate synthase PUS7L

1

0

High-throughput

0.513

High

849912

ASF1B
Histone chaperone ASF1B

1

0

High-throughput

0.513

High

849913

KANL3
KAT8 regulatory NSL complex subunit 3

1

0

High-throughput

0.513

High

394369

A4
Amyloid-beta precursor protein

1

2

High-throughput

0.501

High

849896

ELP2
Elongator complex protein 2

1

5

Small-scale

0.501

High

418917

TPM3
Tropomyosin alpha-3 chain

1

3

High-throughput

0.500

High

451221

TPM1
Tropomyosin alpha-1 chain

1

3

High-throughput

0.500

High

518616

IMDH2
Inosine-5'-monophosphate dehydrogenase 2

1

1

High-throughput

0.500

High

572899

PRS6A
26S proteasome regulatory subunit 6A

1

2

High-throughput

0.500

High

720018

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.500

High

849880

UBC12
NEDD8-conjugating enzyme Ubc12

1

2

High-throughput

0.500

High

849882

TPM4
Tropomyosin alpha-4 chain

1

3

High-throughput

0.500

High

849889

NACA
Nascent polypeptide-associated complex subunit alpha

1

1

High-throughput

0.500

High

849894

DREB
Drebrin

1

1

High-throughput

0.500

High

126233

ODPX
Pyruvate dehydrogenase protein X component, mitochondrial

1

3

High-throughput

0.489

High

489723

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

1

3

High-throughput

0.489

High

118245

HAX1
HCLS1-associated protein X-1

1

1

High-throughput

0.481

High

609765

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

1

1

High-throughput

0.481

High

165830

KDM6B
Lysine-specific demethylase 6B

1

7

Small-scale

0.479

High

226915

PRKN
E3 ubiquitin-protein ligase parkin

1

2

High-throughput

0.479

High

353053

IL2RA
Interleukin-2 receptor subunit alpha

1

2

Small-scale

0.479

High

377195

GCR
Glucocorticoid receptor

1

19

Small-scale

0.479

High

414466

PRGR
Progesterone receptor

1

17

Small-scale

0.479

High

501020

IRF1
Interferon regulatory factor 1

1

20

Small-scale

0.479

High

540811

PO2F1
POU domain, class 2, transcription factor 1

1

6

Small-scale

0.479

High

552280

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.479

High

560469

PRLR
Prolactin receptor

1

20

Small-scale

0.479

High

569421

CEBPB
CCAAT/enhancer-binding protein beta

1

8

High-throughput

0.479

High

596519

CD3Z
T-cell surface glycoprotein CD3 zeta chain

1

1

Small-scale

0.479

High

849906

DNJA3
DnaJ homolog subfamily A member 3, mitochondrial

1

1

Small-scale

0.479

High

849917

TBX21
T-box transcription factor TBX21

1

6

Small-scale

0.479

High

111137

I6L957
Heterogeneous nuclear ribonucleoproteins A2/B1

1

2

High-throughput

0.470

High

849895

DMRTA
Doublesex- and mab-3-related transcription factor A1

1

0

High-throughput

0.460

High

849897

AFTIN
Aftiphilin

1

0

High-throughput

0.460

High

849904

TFG
Protein TFG

1

0

High-throughput

0.460

High

849916

SRTD1
SERTA domain-containing protein 1

1

0

High-throughput

0.460

High

849915

UBQL2
Ubiquilin-2

1

0

High-throughput

0.458

High

279485

FLOT1
Flotillin-1

1

5

High-throughput

0.457

High

849891

FLOT2
Flotillin-2

1

5

High-throughput

0.457

High

849905

CBP
CREB-binding protein

1

14

Small-scale

0.445

High

849901

ADA32
Disintegrin and metalloproteinase domain-containing protein 32

2

0

High-throughput

0.328

High

849909

TRMO
tRNA

2

0

High-throughput

0.328

High

849746

SUOX
Sulfite oxidase, mitochondrial

2

0

High-throughput

0.316

High


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Last updated: 15 Jul 2024