Protein: P90786
Piwi-like protein 1

Gene: P90786, prg-1
Organism: Caenorhabditis elegans
Interactions: 127
UniProt ID: P90786

Gene Ontology (top 5):
GO:0004521 - RNA endonuclease activity
GO:0005634 - nucleus
GO:0007276 - gamete generation
GO:0007283 - spermatogenesis
GO:0022414 - reproductive process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1018372

P90786
Piwi-like protein 1

1

11

High-throughput

0.618

High

264119

O62213
CSD domain-containing protein

1

9

High-throughput

0.541

High

1018422

DEPS1
P-granule-associated protein deps-1

1

0

High-throughput

0.537

High

67188

A6PVA1
NudC domain-containing protein 1

1

2

High-throughput

0.479

High

95447

E1NZ12
WW domain-containing protein

1

3

High-throughput

0.479

High

110740

UBP48
Ubiquitin carboxyl-terminal hydrolase usp-48

1

2

High-throughput

0.479

High

110846

G5ECH0
Histone deacetylase

1

3

High-throughput

0.479

High

112477

SMU1
Smu-1 suppressor of mec-8 and unc-52 protein

1

1

High-throughput

0.479

High

145897

O02325
PRotein arginine MethylTransferase

1

4

High-throughput

0.479

High

195309

O16297
DNA replication licensing factor MCM7

1

1

High-throughput

0.479

High

196239

RUVB1
RuvB-like 1

1

5

High-throughput

0.479

High

233789

O45246
Heat shock protein 70

1

9

High-throughput

0.479

High

759894

GLH1
ATP-dependent RNA helicase glh-1

1

10

High-throughput

0.479

High

853164

LIN5
Spindle apparatus protein lin-5

1

3

High-throughput

0.479

High

1018369

PAF1
RNA polymerase II-associated factor 1 homolog

1

2

High-throughput

0.479

High

1018383

GLD1
Female germline-specific tumor suppressor gld-1

1

4

Small-scale

0.479

High

1018392

MEP1
MOG interacting and ectopic P-granules protein 1

1

1

High-throughput

0.479

High

1018396

Q22059
WD_REPEATS_REGION domain-containing protein

1

1

High-throughput

0.479

High

1018397

Q22318
RRM domain-containing protein

1

11

High-throughput

0.479

High

1018399

Q22751
J domain-containing protein

1

8

High-throughput

0.479

High

1018420

RUVB2
RuvB-like 2

1

5

High-throughput

0.479

High

1018423

Q9N350
SHSP domain-containing protein

1

4

High-throughput

0.479

High

1018425

Q9N3S7
histone acetyltransferase

1

7

High-throughput

0.479

High

1018426

CPSF1
Probable cleavage and polyadenylation specificity factor subunit 1

1

5

High-throughput

0.479

High

1018430

Q9TXM1
Uncharacterized protein

1

2

High-throughput

0.479

High

1018434

LIN41
Protein lin-41

1

20

High-throughput

0.479

High

1018439

Q9XUW5
RNA helicase

1

7

High-throughput

0.479

High

1018441

Q9XVS2
RRM domain-containing protein

1

12

High-throughput

0.479

High

110173

PGL3
Guanyl-specific ribonuclease pgl-3

1

0

High-throughput

0.458

High

110322

G5EC16
Survival motor neuron protein

1

0

High-throughput

0.458

High

116572

H8ESF3
SWI/SNF complex subunit SMARCC2

1

0

High-throughput

0.458

High

234254

TAF9
Transcription initiation factor TFIID subunit 9

1

0

High-throughput

0.458

High

759312

RFC5
Probable replication factor C subunit 5

1

0

High-throughput

0.458

High

759645

IF5A1
Eukaryotic translation initiation factor 5A-1

1

0

High-throughput

0.458

High

1018375

BAF1
Barrier-to-autointegration factor 1

1

0

High-throughput

0.458

High

1018385

WDR51
WD repeat-containing protein wdr-5.1

1

0

High-throughput

0.458

High

1018389

Q19731
Tudor domain-containing protein

1

0

High-throughput

0.458

High

1018394

Q21831
SWI/SNF Subunit INI1 DNA binding domain-containing protein

1

0

High-throughput

0.458

High

1018403

CD112
Cyclin-dependent kinase 11.2

1

0

High-throughput

0.458

High

1018414

Q9BHL3
C2H2-type domain-containing protein

1

0

High-throughput

0.458

High

1018416

Q9BKQ7
Early ELOngation arrest

1

0

High-throughput

0.458

High

1018436

Q9XUS9
Rac GTPase-activating protein 1

1

0

High-throughput

0.458

High

196975

O18302
Golgi-associated PDZ and coiled-coil motif-containing protein

1

1

High-throughput

0.451

High

196935

O18301
PDZ domain-containing protein

1

1

High-throughput

0.439

High

72228

A8XMZ5
EF-hand domain-containing protein

1

1

High-throughput

0.437

High

84237

BRCA1
Breast cancer type 1 susceptibility protein homolog

1

6

High-throughput

0.437

High

109089

G4S034
Spectrin alpha chain

1

4

High-throughput

0.437

High

110207

G5EBX0
Kinesin motor domain-containing protein

1

1

High-throughput

0.437

High

113326

G5EFG4
ABC transporter domain-containing protein

1

1

High-throughput

0.437

High

114283

G5EGT7
Eukaryotic translation initiation factor 5B

1

1

High-throughput

0.437

High

115567

H2KZN0
RRM domain-containing protein

1

17

High-throughput

0.437

High

115860

H2L0B1
Dipeptidyl Peptidase Four

1

1

High-throughput

0.437

High

116148

APC10
Anaphase-promoting complex subunit 10

1

5

High-throughput

0.437

High

116255

H2L2L1
LIM zinc-binding domain-containing protein

1

1

High-throughput

0.437

High

145312

O01905
Bromo domain-containing protein

1

4

High-throughput

0.437

High

196696

O18032
Coiled-coil domain-containing protein 13

1

4

High-throughput

0.437

High

534396

ACT2
Actin-2

1

3

High-throughput

0.437

High

773410

AP1M
AP-1 complex subunit mu-1-I

1

1

High-throughput

0.437

High

909838

CYP10
Peptidyl-prolyl cis-trans isomerase 10

1

1

High-throughput

0.437

High

909840

CYP11
Peptidyl-prolyl cis-trans isomerase 11

1

2

High-throughput

0.437

High

1018373

U2AF2
Splicing factor U2AF 65 kDa subunit

1

10

High-throughput

0.437

High

1018374

RL13
Large ribosomal subunit protein eL13

1

2

High-throughput

0.437

High

1018377

MLRH
Myosin regulatory light chain

1

1

High-throughput

0.437

High

1018378

CLIK2
Calponin-like protein clik-2

1

2

High-throughput

0.437

High

1018379

Q09975
LYSozyme

1

2

High-throughput

0.437

High

1018382

WDR1
Actin-interacting protein 1

1

2

High-throughput

0.437

High

1018386

Q18886
Charged multivesicular body protein 4b

1

1

High-throughput

0.437

High

1018387

RCORB
REST corepressor spr-1

1

1

High-throughput

0.437

High

1018391

Q20528
C-type lectin domain-containing protein

1

1

High-throughput

0.437

High

1018393

Q21829
ATP-dependent DNA helicase II subunit 2

1

2

High-throughput

0.437

High

1018395

PRO1
Pre-rRNA-processing protein pro-1

1

4

High-throughput

0.437

High

1018401

TPM1
Tropomyosin isoforms a/b/d/f

1

1

High-throughput

0.437

High

1018405

Q2WF61
Anaphase-promoting complex subunit 10

1

5

High-throughput

0.437

High

1018406

Q93339
Pre-mRNA processing factor 4

1

1

High-throughput

0.437

High

1018418

Q9BL39
HMG box domain-containing protein

1

2

High-throughput

0.437

High

1018419

MES6
Polycomb protein mes-6

1

4

High-throughput

0.437

High

1018428

Q9N4N4
Actin-related protein 4

1

4

High-throughput

0.437

High

1018432

Q9TYL0
C-type lectin domain-containing protein

1

1

High-throughput

0.437

High

1018440

MLC5
Myosin-2 essential light chain

1

3

High-throughput

0.437

High

1018442

Q9XW58
U3 small nucleolar ribonucleoprotein protein MPP10

1

1

High-throughput

0.437

High

263858

O61775
Very Early Transcript

2

0

High-throughput

0.320

High

1018381

GCP
Bifunctional glyoxylate cycle protein

1

0

High-throughput

0.282

High

1018407

Q93576
Nucleoside diphosphate kinase

1

0

High-throughput

0.282

High

63483

SIN3
Paired amphipathic helix protein sin-3

1

0

High-throughput

0.249

Low

64198

A5Z2V0
CID domain-containing protein

1

0

High-throughput

0.249

Low

109054

CDC26
Anaphase-promoting complex subunit CDC26

1

0

High-throughput

0.249

Low

109123

G4SL51
DUF1080 domain-containing protein

1

0

High-throughput

0.249

Low

112721

G5EEN7
Sjogren's syndrome/scleroderma autoantigen 1

1

0

High-throughput

0.249

Low

112994

G5EF57
BAR domain-containing protein

1

0

High-throughput

0.249

Low

114989

H2KML5
RING-type E3 ubiquitin transferase

1

0

High-throughput

0.249

Low

144621

TMOD
Tropomodulin

1

0

High-throughput

0.249

Low

195480

O16486
N-terminal methionine N(alpha)-acetyltransferase NatC

1

0

High-throughput

0.249

Low

195631

O16655
Seven TM Receptor

1

0

High-throughput

0.249

Low

196050

CPSF2
Probable cleavage and polyadenylation specificity factor subunit 2

1

0

High-throughput

0.249

Low

196684

O18015
Ground-like domain-containing protein

1

0

High-throughput

0.249

Low

231941

O44159
Small ribosomal subunit protein uS10 domain-containing protein

1

0

High-throughput

0.249

Low

233317

O44499
BSD domain-containing protein

1

0

High-throughput

0.249

Low

233646

O44956
KNL

1

0

High-throughput

0.249

Low

759221

YLU5
Uncharacterized protein F10E9.5

1

0

High-throughput

0.249

Low

1018376

DYF7
Protein dyf-7

1

0

High-throughput

0.249

Low

1018380

Q0KHC0
Guanine nucleotide exchange factor MSS4

1

0

High-throughput

0.249

Low

1018384

EDG1
Protein edg-1

1

0

High-throughput

0.249

Low

1018388

Q19122
Non-specific serine/threonine protein kinase

1

0

High-throughput

0.249

Low

1018390

Q20453
LisH domain-containing protein

1

0

High-throughput

0.249

Low

1018398

SSU72
RNA polymerase II subunit A C-terminal domain phosphatase ssup-72

1

0

High-throughput

0.249

Low

1018400

DYL1
Dynein light chain 1, cytoplasmic

1

0

High-throughput

0.249

Low

1018402

NDX3
Nudix hydrolase 3

1

0

High-throughput

0.249

Low

1018404

Q2A949
PHD finger protein 10

1

0

High-throughput

0.249

Low

1018408

Q93716
Cleavage and polyadenylation specificity factor subunit 5

1

0

High-throughput

0.249

Low

1018409

Q93718
PWWP domain-containing protein

1

0

High-throughput

0.249

Low

1018410

Q93726
PB1 domain-containing protein

1

0

High-throughput

0.249

Low

1018411

Q95PZ7
Proteasome activator complex subunit 3

1

0

High-throughput

0.249

Low

1018412

Q95QS3
Small ribosomal subunit protein mS26

1

0

High-throughput

0.249

Low

1018413

Q95Y10
Delta-like protein

1

0

High-throughput

0.249

Low

1018415

Q9BI86
Spindle and Kinetochore-Associated protein homolog

1

0

High-throughput

0.249

Low

1018417

Q9BKU3
Eukaryotic translation initiation factor 2 subunit 1

1

0

High-throughput

0.249

Low

1018421

Q9N2X3
KNL

1

0

High-throughput

0.249

Low

1018424

Q9N3E8
PH domain-containing protein

1

0

High-throughput

0.249

Low

1018427

Q9N4I5
Increased recombination centers protein 6

1

0

High-throughput

0.249

Low

1018429

Q9NF23
Glutaredoxin domain-containing protein

1

0

High-throughput

0.249

Low

1018431

Q9TXQ8
Nucleic acid-binding, OB-fold protein

1

0

High-throughput

0.249

Low

1018433

Q9U2G6
Lipoprotein

1

0

High-throughput

0.249

Low

1018435

ADD1
Adducin-related protein 1

1

0

High-throughput

0.249

Low

1018437

Q9XUT6
DUF1176 domain-containing protein

1

0

High-throughput

0.249

Low

1018438

Q9XUT9
VWFA domain-containing protein

1

0

High-throughput

0.249

Low

1018443

Q9XWX8
ZM domain-containing protein

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025