HitPredict

Interactor 1: Q18886 (Q18886)
Charged multivesicular body protein 4b
Gene: vps-32.1

Interactor 2: Q9TXI3 (Q9TXI3)
Charged multivesicular body protein 1b
Gene: did-2

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	29129923
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Snf7~Snf7
Common GO terms	GO:0000815 - ESCRT III complex GO:0005771 - multivesicular body GO:0010008 - endosome membrane
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 221 Ce			1 205
+	Ce
		1166323 Q18886_CAEEL (1-221): 1.41e-58: 185: 100.00		Q9U2F6_CAEEL (4-204): 1.26e-44: 150: 23.25
+	Ce
		1166321 Q18886_CAEEL (1-221): 1.41e-58: 185: 100.00		Q9GYK4_CAEEL (4-204): 1.33e-39: 136: 15.92
+	Dm
		1345401 CHM4_DROME (1-220): 3.18e-50: 164: 54.63		Q9VRJ5_DROME (4-204): 1.17e-42: 144: 16.83
+	Hs
		97297 E9PSI1_HUMAN (1-203): 1.3e-62: 210: 57.01		CHM4B_HUMAN (4-194): 2.55e-24: 97.1: 20.60
+	Dm
		1345391 CHM4_DROME (1-220): 3.18e-50: 164: 54.63		Q95SH2_DROME (6-204): 2.96e-39: 135: 56.00
+	Dm
		1345400 CHM4_DROME (1-220): 3.18e-50: 164: 54.63		Q9VN02_DROME (3-204): 5.42e-39: 135: 11.16
+	Dm
		1345394 CHM4_DROME (1-220): 3.18e-50: 164: 54.63		Q9VBI3_DROME (5-196): 4.46e-38: 133: 21.35
+	Hs
		221882 CHM4B_HUMAN (1-221): 3.71e-46: 154: 61.33		CHM2A_HUMAN (4-186): 1.59e-41: 141: 23.50
+	Hs
		1433130 CHM4B_HUMAN (1-221): 3.71e-46: 154: 61.33		CHM2B_HUMAN (4-202): 2.14e-40: 138: 17.73
+	At
		102953 F4JXR3_ARATH (4-214): 3.57e-47: 158: 18.15		VP241_ARATH (4-204): 8.98e-36: 127: 14.22
+	Hs
		1433081 CHM4B_HUMAN (1-221): 3.71e-46: 154: 61.33		CHM1A_HUMAN (10-204): 1.43e-37: 130: 48.47
+	Hs
		1273179 CHM4B_HUMAN (1-221): 3.71e-46: 154: 61.33		CHM1B_HUMAN (8-204): 9.28e-36: 126: 55.33
+	Hs
		1433095 CHM4B_HUMAN (1-221): 3.71e-46: 154: 61.33		CHMP5_HUMAN (4-192): 4.21e-29: 109: 15.98
+	Hs
		1385865 CHM4C_HUMAN (1-220): 4.2e-47: 156: 50.64		CHM4B_HUMAN (4-194): 2.55e-24: 97.1: 20.60
+	Mm
		1424143 CHM4B_MOUSE (1-221): 2.77e-46: 154: 60.89		CHM4B_MOUSE (4-194): 2.63e-24: 97.1: 20.60
+	Hs
		1433075 CHM4B_HUMAN (1-221): 3.71e-46: 154: 61.33		CHM4B_HUMAN (4-194): 2.55e-24: 97.1: 20.60
+	Dm
		1345404 CHM4_DROME (1-220): 3.18e-50: 164: 54.63		CHMP5_DROME (4-192): 1.77e-19: 84.4: 13.92
+	Hs
		1385854 CHM4C_HUMAN (1-220): 4.2e-47: 156: 50.64		CHM4A_HUMAN (3-194): 4.34e-19: 83.2: 19.21
+	Hs
		1417742 CHM4B_HUMAN (1-221): 3.71e-46: 154: 61.33		CHM4A_HUMAN (3-194): 4.34e-19: 83.2: 19.21