Protein: HRD1
E3 ubiquitin-protein ligase hrd-1 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase hrd-1) (Suppressor/enhancer of lin-12)

Gene: HRD1, sel-11
Organism: Caenorhabditis elegans
Interactions: 9
UniProt ID: Q20798

Gene Ontology (top 5):
GO:0005789 - endoplasmic reticulum membrane
GO:0008270 - zinc ion binding
GO:0008593 - regulation of Notch signaling pathway
GO:0010468 - regulation of gene expression
GO:0012505 - endomembrane system

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

304066

PSDE
26S proteasome non-ATPase regulatory subunit 14

3

9

High-throughput

0.635

High

1169960

Q9U1U4
UBC core domain-containing protein

1

20

Small-scale

0.555

High

113079

BIR1
Chromosomal passenger complex protein bir-1

1

2

High-throughput

0.494

High

1169958

Q21319
Phospholipid scramblase

1

1

High-throughput

0.494

High

112336

SRC1
Tyrosine protein-kinase src-1

1

20

High-throughput

0.464

High

1169959

BET1
Bromodomain-containing protein bet-1

1

2

High-throughput

0.451

High

1067107

MET16
U6 small nuclear RNA

1

0

High-throughput

0.282

High

1165134

CKS1
Cyclin-dependent kinases regulatory subunit

1

0

High-throughput

0.282

High

884860

FEM2
Protein phosphatase fem-2

1

0

High-throughput

0.251

Low


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Last updated: 11Aug2025