Protein: SGK1
Serine/threonine-protein kinase sgk-1 (EC 2.7.11.1) (Serum- and glucocorticoid-inducible kinase homolog) (Serum/glucocorticoid-regulated kinase 1)

Gene: SGK1, sgk-1
Organism: Caenorhabditis elegans
Interactions: 21
UniProt ID: Q2PJ68

Gene Ontology (top 5):
GO:0002119 - nematode larval development
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005547 - phosphatidylinositol-3,4,5-trisphosphate binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1179624

PDPK1
3-phosphoinositide-dependent protein kinase 1

2

17

Small-scale

0.789

High

1165182

AKT1
Serine/threonine-protein kinase akt-1

1

16

Small-scale

0.751

High

1179622

AKT2
Serine/threonine-protein kinase akt-2

1

17

Small-scale

0.751

High

195816

FOXO
Forkhead box protein O

2

13

Small-scale

0.657

High

760187

SKN1
Protein skinhead-1

1

2

Small-scale

0.550

High

196779

2A51
Serine/threonine-protein phosphatase 2A regulatory subunit pptr-1

1

3

Small-scale

0.515

High

1166602

MON2
Monensin-resistant homolog 2

1

4

Small-scale

0.504

High

760045

GLH1
ATP-dependent RNA helicase glh-1

1

11

High-throughput

0.479

High

1169940

ARL1
ADP-ribosylation factor-like protein 1

1

2

Small-scale

0.479

High

1179620

DPY21
Lysine-specific demethylase 9

1

6

Small-scale

0.479

High

1179621

AFG3
AFG3-like protein spg-7

1

4

Small-scale

0.479

High

113574

G5EFW8
ADP/ATP translocase

1

9

Small-scale

0.437

High

114267

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 homolog

1

3

Small-scale

0.437

High

232937

O44490
ELKS/RAB6-interacting/CAST family member 2

1

20

High-throughput

0.437

High

234325

O45865
ADP/ATP translocase

1

9

Small-scale

0.437

High

827135

MPCP
Phosphate carrier protein, mitochondrial

1

11

Small-scale

0.437

High

1068059

ATPD
ATP synthase subunit delta, mitochondrial

1

1

Small-scale

0.437

High

1170435

VDAC
Probable voltage-dependent anion-selective channel

1

5

Small-scale

0.437

High

1179623

PICAL
Phosphatidylinositol-binding clathrin assembly protein unc-11

1

2

Small-scale

0.437

High

1179619

Q6AW08
Conserved oligomeric Golgi complex subunit 3

1

0

Small-scale

0.288

High

1165050

Q17763
ATP synthase subunit d, mitochondrial

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025