Protein: GNS
N-acetylglucosamine-6-sulfatase (EC 3.1.6.14) (Glucosamine-6-sulfatase) (G6S)

Gene: GNS
Organism: Homo sapiens
Interactions: 37
UniProt ID: P15586

Gene Ontology (top 5):
GO:0005539 - glycosaminoglycan binding
GO:0005576 - extracellular region
GO:0006027 - glycosaminoglycan catabolic process
GO:0008449 - N-acetylglucosamine-6-sulfatase activity
GO:0008484 - sulfuric ester hydrolase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

549097

SULF2
Extracellular sulfatase Sulf-2

2

7

High-throughput

0.811

High

282027

CLPX
ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial

2

1

High-throughput

0.574

High

549100

SUMF1
Formylglycine-generating enzyme

2

13

High-throughput

0.574

High

549105

FKB14
Peptidyl-prolyl cis-trans isomerase FKBP14

2

3

High-throughput

0.574

High

499510

CH60
60 kDa heat shock protein, mitochondrial

1

2

High-throughput

0.536

High

514755

MPRI
Cation-independent mannose-6-phosphate receptor

1

6

High-throughput

0.536

High

549106

UGGG1
UDP-glucose:glycoprotein glucosyltransferase 1

1

1

High-throughput

0.536

High

549103

FBX6
F-box only protein 6

2

10

High-throughput

0.533

High

549085

CAN2
Calpain-2 catalytic subunit

1

0

High-throughput

0.513

High

549102

PAR6B
Partitioning defective 6 homolog beta

1

0

High-throughput

0.513

High

549093

CUL1
Cullin-1

1

2

High-throughput

0.489

High

549108

FBX2
F-box only protein 2

1

10

High-throughput

0.489

High

129687

AGRIN
Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment

1

3

High-throughput

0.479

High

411982

FYN
Tyrosine-protein kinase Fyn

1

2

High-throughput

0.479

High

522747

SRC
Proto-oncogene tyrosine-protein kinase Src

1

2

High-throughput

0.479

High

549086

EFNA1
Ephrin-A1

1

2

High-throughput

0.479

High

549088

EFNA4
Ephrin-A4

1

2

High-throughput

0.479

High

549091

GRB2
Growth factor receptor-bound protein 2

1

4

High-throughput

0.479

High

549096

TM11B
Transmembrane protease serine 11B

1

6

High-throughput

0.479

High

549107

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

503374

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

549090

RHOA
Transforming protein RhoA

1

0

High-throughput

0.458

High

517035

PCNA
Proliferating cell nuclear antigen

1

1

High-throughput

0.457

High

205001

TGON2
Trans-Golgi network integral membrane protein 2

1

6

High-throughput

0.437

High

337334

ABL1
Tyrosine-protein kinase ABL1

1

2

High-throughput

0.437

High

549084

NCK1
SH2/SH3 adapter protein NCK1

1

3

High-throughput

0.437

High

549087

EFNA3
Ephrin-A3

1

2

High-throughput

0.437

High

549094

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.437

High

549098

TM192
Transmembrane protein 192

1

1

High-throughput

0.437

High

549104

TMPS4
Transmembrane protease serine 4

1

5

High-throughput

0.437

High

549099

POC5
Centrosomal protein POC5

1

2

High-throughput

0.407

High

549101

ENASE
Cytosolic endo-beta-N-acetylglucosaminidase

2

0

High-throughput

0.328

High

116769

KIF2A
Kinesin-like protein KIF2A

1

0

High-throughput

0.279

Low

318921

CEP43
Centrosomal protein 43

1

0

High-throughput

0.279

Low

549092

G3BP1
Ras GTPase-activating protein-binding protein 1

1

0

High-throughput

0.279

Low

549089

ABCE1
ATP-binding cassette sub-family E member 1

1

0

High-throughput

0.249

Low

549095

ATG9A
Autophagy-related protein 9A

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024