Protein: PCNP
PEST proteolytic signal-containing nuclear protein (PCNP) (PEST-containing nuclear protein)

Gene: PCNP
Organism: Homo sapiens
Interactions: 81
UniProt ID: Q8WW12

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0007049 - cell cycle
GO:0016567 - protein ubiquitination
GO:0016604 - nuclear body

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1262133

UHRF2
E3 ubiquitin-protein ligase UHRF2

3

0

Small-scale

0.636

High

347438

MYC
Myc proto-oncogene protein

2

1

High-throughput

0.584

High

808797

YAP1
Transcriptional coactivator YAP1

2

0

Small-scale

0.559

High

370090

ESR1
Estrogen receptor

2

0

High-throughput

0.547

High

1262139

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.543

High

850122

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

1

High-throughput

0.536

High

1054461

RBM39
RNA-binding protein 39

1

1

High-throughput

0.536

High

1202016

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

1

High-throughput

0.536

High

1262131

SPF45
Splicing factor 45

1

1

High-throughput

0.536

High

1262142

SF3B6
Splicing factor 3B subunit 6

1

1

High-throughput

0.536

High

117777

MYO1C
Unconventional myosin-Ic

1

0

High-throughput

0.513

High

207079

XRCC3
DNA repair protein XRCC3

1

0

High-throughput

0.513

High

268803

SF3B1
Splicing factor 3B subunit 1

1

0

High-throughput

0.513

High

441339

RU2B
U2 small nuclear ribonucleoprotein B''

1

0

High-throughput

0.513

High

539073

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

1

0

High-throughput

0.513

High

726954

FUS
RNA-binding protein FUS

1

0

High-throughput

0.513

High

911912

RUXF
Small nuclear ribonucleoprotein F

1

0

High-throughput

0.513

High

912523

SMD2
Small nuclear ribonucleoprotein Sm D2

1

0

High-throughput

0.513

High

1073703

SF3A2
Splicing factor 3A subunit 2

1

0

High-throughput

0.513

High

1074191

SF3A1
Splicing factor 3A subunit 1

1

0

High-throughput

0.513

High

1126068

DCA17
DDB1- and CUL4-associated factor 17

1

0

High-throughput

0.513

High

1262132

CAR19
Caspase recruitment domain-containing protein 19

1

0

High-throughput

0.513

High

162096

HNRDL
Heterogeneous nuclear ribonucleoprotein D-like

1

0

High-throughput

0.493

High

1262129

KLK6
Kallikrein-6

1

0

High-throughput

0.493

High

198942

RFOX2
RNA binding protein fox-1 homolog 2

1

1

High-throughput

0.481

High

232948

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

1

1

High-throughput

0.479

High

331853

NSD2
Histone-lysine N-methyltransferase NSD2

1

1

Small-scale

0.479

High

360214

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

1

High-throughput

0.479

High

379655

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.479

High

553285

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.479

High

569901

CEBPB
CCAAT/enhancer-binding protein beta

1

1

High-throughput

0.479

High

1024383

UBP4
Ubiquitin carboxyl-terminal hydrolase 4

1

1

High-throughput

0.479

High

1026490

RFA4
Replication protein A 30 kDa subunit

1

1

High-throughput

0.479

High

1080163

EZH2
Histone-lysine N-methyltransferase EZH2

1

1

High-throughput

0.479

High

117428

BACH
Cytosolic acyl coenzyme A thioester hydrolase

1

0

High-throughput

0.458

High

244702

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.458

High

374602

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

504472

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

523897

XRCC6
X-ray repair cross-complementing protein 6

1

0

High-throughput

0.458

High

651791

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

668854

PML
Protein PML

1

0

High-throughput

0.458

High

718046

BMI1
Polycomb complex protein BMI-1

1

0

High-throughput

0.458

High

721014

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

742431

SYUA
Alpha-synuclein

1

0

High-throughput

0.458

High

781404

BCL6
B-cell lymphoma 6 protein

1

0

High-throughput

0.458

High

800043

VDAC2
Voltage-dependent anion-selective channel protein 2

1

0

High-throughput

0.458

High

935034

H31
Histone H3.1

1

0

High-throughput

0.458

High

1063986

TNIP1
TNFAIP3-interacting protein 1

1

0

High-throughput

0.458

High

1081340

E2F4
Transcription factor E2F4

1

0

High-throughput

0.458

High

1118328

GRAP1
GRIP1-associated protein 1

1

0

High-throughput

0.458

High

1146134

DCA15
DDB1- and CUL4-associated factor 15

1

0

High-throughput

0.458

High

1188621

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

1192138

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

0

High-throughput

0.458

High

1200523

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

1232675

FBXW8
F-box/WD repeat-containing protein 8

1

0

High-throughput

0.458

High

1262130

CSN5
COP9 signalosome complex subunit 5

1

0

High-throughput

0.458

High

1262134

ANM1
Protein arginine N-methyltransferase 1

1

0

High-throughput

0.458

High

1262137

RAD18
E3 ubiquitin-protein ligase RAD18

1

0

High-throughput

0.458

High

1262140

PD1L1
Programmed cell death 1 ligand 1

1

0

High-throughput

0.458

High

1262141

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1146665

A16L1
Autophagy-related protein 16-1

1

1

High-throughput

0.437

High

1075704

SF01
Splicing factor 1

1

0

High-throughput

0.426

High

831518

CEBPA
CCAAT/enhancer-binding protein alpha

1

1

High-throughput

0.408

High

1130376

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

2

0

High-throughput

0.298

High

311414

PAPS2
Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2

1

0

High-throughput

0.279

Low

326338

BPNT1
3'(2'),5'-bisphosphate nucleotidase 1

1

0

High-throughput

0.279

Low

573824

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

0

High-throughput

0.279

Low

899913

OSTN
Osteocrin

1

0

High-throughput

0.279

Low

1062600

EMC2
ER membrane protein complex subunit 2

1

0

High-throughput

0.279

Low

1088575

MIC60
MICOS complex subunit MIC60

1

0

High-throughput

0.279

Low

1126167

MTX3
Metaxin-3

1

0

High-throughput

0.279

Low

1233903

EMC5
ER membrane protein complex subunit 5

1

0

High-throughput

0.279

Low

1262135

MIC25
MICOS complex subunit MIC25

1

0

High-throughput

0.279

Low

1262136

F107B
Protein FAM107B

1

0

High-throughput

0.279

Low

1262143

SAM50
Sorting and assembly machinery component 50 homolog

1

0

High-throughput

0.279

Low

894258

CDC42
Cell division control protein 42 homolog

1

0

High-throughput

0.261

Low

322924

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.249

Low

914249

RB11A
Ras-related protein Rab-11A

1

0

High-throughput

0.249

Low

981900

RON
Macrophage-stimulating protein receptor

1

0

High-throughput

0.249

Low

1170993

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1262138

MARH5
E3 ubiquitin-protein ligase MARCHF5

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024