Protein: Q9N6D8
GH11591p (P53, isoform A) (P53, isoform C) (Transcription factor) (p53 tumor suppressor-like protein) (p53-like regulator of apoptosis and cell cycle)

Gene: Q9N6D8, p53
Organism: Drosophila melanogaster
Interactions: 193
UniProt ID: Q9N6D8

Gene Ontology (top 5):
GO:0000976 - transcription cis-regulatory region binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001091 - RNA polymerase II general transcription initiation factor binding
GO:0001097 - TFIIH-class transcription factor complex binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1445134

Q9N6D8
GH11591p

3

14

Small-scale

0.827

High

1268462

Q7KNM2
Dorsal interacting protein 4

5

8

Small-scale

0.715

High

1445157

Q9VDQ5
RE74560p

3

3

High-throughput

0.658

High

1445149

TOPRS
E3 ubiquitin-protein ligase Topors

2

3

Small-scale

0.640

High

1069302

Q0E8J0
MOG interacting and ectopic P-granules protein 1

2

4

High-throughput

0.620

High

1445145

Q9V4D4
TBP-associated factor 3

2

1

Small-scale

0.619

High

583693

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

2

4

Small-scale

0.595

High

117667

L0MPR7
Twin of eyeless, isoform C

2

3

High-throughput

0.586

High

384922

HSP26
Heat shock protein 26

2

5

Small-scale

0.584

High

1302159

TAD2B
Transcriptional adapter 2b

2

2

Small-scale

0.584

High

1342979

PHO
Polycomb protein PHO

1

8

High-throughput

0.578

High

451817

NOTCH
Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein]

1

6

High-throughput

0.575

High

1445163

Q9VGI6
FI06048p

2

7

High-throughput

0.566

High

669566

UBCD6
Ubiquitin-conjugating enzyme E2-17 kDa

1

3

Small-scale

0.561

High

1269722

Q7KUA4
SUMO-activating enzyme subunit

1

2

Small-scale

0.552

High

1378158

CYCG
Cyclin G

1

8

Small-scale

0.552

High

1445212

Q9XYM5
LD27861p

1

10

Small-scale

0.552

High

627225

DLL
Homeotic protein distal-less

1

6

High-throughput

0.541

High

682703

TUD
Protein tudor

1

4

High-throughput

0.541

High

731982

CROC
Fork head domain-containing protein crocodile

1

11

High-throughput

0.541

High

1202299

Q59DN5
FI18025p1

1

8

High-throughput

0.541

High

1267502

Q7KMH9
BcDNA.LD26050

1

17

High-throughput

0.541

High

1269190

Q7KT79
C2H2-type domain-containing protein

1

7

High-throughput

0.541

High

1445152

Q9VAT1
Uncharacterized protein, isoform A

1

8

High-throughput

0.541

High

1445161

KMT5A
Histone-lysine N-methyltransferase Set8

1

9

High-throughput

0.541

High

1445179

Q9VNE0
PHD and RING finger domain-containing protein 1

1

10

High-throughput

0.541

High

1445180

CHNMO
Zinc finger protein chinmo

1

12

High-throughput

0.541

High

1445181

BOWEL
Protein bowel

1

6

High-throughput

0.541

High

1445182

Q9VQY7
Uncharacterized protein, isoform A

1

6

High-throughput

0.541

High

1445197

Q9VWK5
GH15225p

1

5

High-throughput

0.541

High

1445207

Q9W1A8
Helicase ARIP4

1

11

High-throughput

0.541

High

1286106

TULP
Protein king tubby

1

0

High-throughput

0.518

High

1445146

MED26
Mediator of RNA polymerase II transcription subunit 26

1

0

High-throughput

0.518

High

1445204

POF
Protein painting of fourth

1

0

High-throughput

0.518

High

1445205

Q9W135
RNase NYN domain-containing protein

1

0

High-throughput

0.518

High

84310

DIMM
Protein dimmed

1

1

High-throughput

0.508

High

478827

BCD
Homeotic protein bicoid

1

6

High-throughput

0.508

High

1176196

RAD51
DNA repair protein Rad51 homolog

1

3

High-throughput

0.508

High

1379225

Q961D1
Cyclin-K

1

9

High-throughput

0.508

High

1445201

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

6

Small-scale

0.501

High

1378458

Q95U38
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial

1

1

High-throughput

0.494

High

1262701

Q7JWW6
Adenosine kinase

1

0

High-throughput

0.486

High

68225

A8DYA3
Toutatis, isoform E

1

20

High-throughput

0.481

High

69043

A8JRE3
Without children, isoform B

1

11

High-throughput

0.481

High

713695

ABDA
Homeobox protein abdominal-A

1

2

High-throughput

0.481

High

1014351

UBX
Homeotic protein ultrabithorax

1

3

High-throughput

0.481

High

1355798

Q8WS79
Estrogen-related receptor splice variant

1

9

High-throughput

0.481

High

1445167

Q9VI18
Uncharacterized protein, isoform B

1

1

High-throughput

0.481

High

1445174

Q9VM37
FI17813p1

1

6

High-throughput

0.481

High

51819

GUS
Protein gustavus

1

7

High-throughput

0.479

High

72153

A8WHG9
IP17752p

1

4

High-throughput

0.479

High

118626

M9NF14
IGF-II mRNA-binding protein, isoform L

1

9

High-throughput

0.479

High

120171

M9PCJ7
Utx histone demethylase, isoform E

1

6

Small-scale

0.479

High

122196

M9PHZ1
Transcriptional adaptor 3, isoform C

1

1

Small-scale

0.479

High

304363

O76876
Protein sex-lethal

1

4

High-throughput

0.479

High

304525

AUB
Protein aubergine

1

10

High-throughput

0.479

High

384831

HSP23
Heat shock protein 23

1

5

High-throughput

0.479

High

385000

HSP27
Heat shock protein 27

1

5

Small-scale

0.479

High

447928

TPM1
Tropomyosin-1, isoforms 9A/A/B

1

4

High-throughput

0.479

High

653089

HSF
Heat shock factor protein

1

2

High-throughput

0.479

High

714743

APTE
Protein apterous

1

4

High-throughput

0.479

High

1039160

ERCC3
General transcription and DNA repair factor IIH helicase/translocase subunit XPB

1

5

Small-scale

0.479

High

1055202

AL
Homeobox protein aristaless

1

5

High-throughput

0.479

High

1172632

SIMA
Protein similar

1

7

High-throughput

0.479

High

1174412

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.479

High

1192903

YAP1
Transcriptional coactivator yorkie

1

20

Small-scale

0.479

High

1262363

Q7JVY2
Double parked, isoform A

1

2

High-throughput

0.479

High

1266142

Q7K3W2
Mitochondrial-processing peptidase subunit alpha

1

2

High-throughput

0.479

High

1302128

TRA1
Transcription-associated protein 1

1

7

Small-scale

0.479

High

1321202

Q8MSB3
LD33878p

1

6

High-throughput

0.479

High

1343607

Q8SX72
LD30050p

1

7

High-throughput

0.479

High

1378886

TF2H1
General transcription factor IIH subunit 1

1

1

Small-scale

0.479

High

1379062

CORT
Protein cortex

1

7

High-throughput

0.479

High

1445135

CLASP
CLIP-associating protein

1

1

High-throughput

0.479

High

1445138

GRAU
Transcription factor grauzone

1

7

High-throughput

0.479

High

1445142

NOG1
Nucleolar GTP-binding protein 1

1

2

High-throughput

0.479

High

1445143

ASF1
Histone chaperone asf1

1

2

High-throughput

0.479

High

1445154

ASP
Protein abnormal spindle

1

9

High-throughput

0.479

High

1445155

Q9VCG6
IP14417p1

1

20

High-throughput

0.479

High

1445159

Q9VEF5
Inhibitor of growth protein

1

7

High-throughput

0.479

High

1445169

RTCB
RNA-splicing ligase RtcB homolog

1

1

High-throughput

0.479

High

1445171

Q9VJ86
Leucine-rich PPR motif-containing protein, mitochondrial

1

2

High-throughput

0.479

High

1445173

SIRT1
NAD-dependent histone deacetylase sirtuin-1

1

6

Small-scale

0.479

High

1445175

Q9VM62
LD34181p

1

1

High-throughput

0.479

High

1445176

DAXX
Daxx-like protein

1

11

High-throughput

0.479

High

1445187

Q9VTM2
2-(3-amino-3-carboxypropyl)histidine synthase subunit 1

1

3

High-throughput

0.479

High

1445189

Q9VTZ1
histone acetyltransferase

1

20

Small-scale

0.479

High

1445190

NPRL3
GATOR complex protein NPRL3

1

3

High-throughput

0.479

High

1445191

AGO2
Protein argonaute-2

1

9

High-throughput

0.479

High

1445192

Q9VUR1
General transcription factor IIH subunit 4

1

1

Small-scale

0.479

High

1445200

BAP60
Brahma-associated protein of 60 kDa

1

5

High-throughput

0.479

High

1445209

Q9W3N9
Acetyl-CoA acetyltransferase 1, isoform A

1

1

High-throughput

0.479

High

1179575

ZCHC8
Zinc finger CCHC domain-containing protein 8 homolog

1

1

High-throughput

0.464

High

1344866

Q8SZP2
RE71854p

1

1

High-throughput

0.464

High

1445136

CEG1A
Centaurin-gamma-1A

1

1

High-throughput

0.464

High

1445193

Q9VV49
1-Acylglycerol-3-phosphate O-acyltransferase 4, isoform A

1

1

High-throughput

0.464

High

56171

A1Z9Z7
NADH dehydrogenase

1

0

High-throughput

0.458

High

61225

A2VEF9
PAX-interacting protein 1

1

0

High-throughput

0.458

High

654056

DSX
Protein doublesex

1

0

High-throughput

0.458

High

892377

TAF11
Transcription initiation factor TFIID subunit 11

1

0

High-throughput

0.458

High

1263630

Q7JZD5
Dorsal interacting protein 3

1

0

High-throughput

0.458

High

1445147

PPO2
Phenoloxidase 2

1

0

High-throughput

0.458

High

1445184

Q9VRL0
Cytochrome c1, heme protein, mitochondrial

1

0

High-throughput

0.458

High

1378045

HRD1
E3 ubiquitin-protein ligase HRD1

1

5

Small-scale

0.457

High

86067

B9A0M7
AT31036p

1

1

High-throughput

0.457

High

1285517

MICAL
[F-actin]-monooxygenase Mical

1

2

High-throughput

0.457

High

1321137

Q8MRU2
SD24632p

1

5

High-throughput

0.457

High

1409472

Q9BMQ0
Toutatis

1

20

High-throughput

0.457

High

1445137

Q9U1I0
BIP2 protein

1

1

High-throughput

0.457

High

1445144

Q9V490
GH14454p

1

3

High-throughput

0.457

High

1445186

Q9VSE9
Estrogen-related receptor

1

10

High-throughput

0.457

High

1445203

Q9VZU6
BTB-VII protein domain

1

4

High-throughput

0.457

High

55559

A1Z9G5
Uncharacterized protein, isoform A

1

3

High-throughput

0.439

High

84813

B7Z0I8
Titin

1

5

High-throughput

0.439

High

874992

PRS4
26S proteasome regulatory subunit 4

1

3

High-throughput

0.439

High

920987

ACT3
Actin-57B

1

5

High-throughput

0.439

High

1169417

Q1RL06
Glutathione synthetase 1, isoform G

1

1

High-throughput

0.439

High

1275301

Q7Z2C5
Uncharacterized protein

1

6

High-throughput

0.439

High

1377859

PAN3
PAN2-PAN3 deadenylation complex subunit PAN3

1

12

High-throughput

0.439

High

1445194

Q9VVA9
Zinc finger CCHC domain-containing protein 7

1

1

High-throughput

0.439

High

58594

A1ZBX0
Cilia- and flagella-associated protein 206

1

1

High-throughput

0.437

High

823779

SQH
Myosin regulatory light chain sqh

1

5

High-throughput

0.437

High

857035

ADHX
Alcohol dehydrogenase class-3

1

3

High-throughput

0.437

High

1176719

SAHH
Adenosylhomocysteinase

1

3

High-throughput

0.437

High

1262071

Q7JV09
GH28348p

1

3

High-throughput

0.437

High

1262311

Q7JVN4
Borrelly

1

1

High-throughput

0.437

High

1270161

Q7KVW1
RE73736p

1

4

High-throughput

0.437

High

1302836

Q8IH13
LD21452p

1

1

High-throughput

0.437

High

1306261

Q8IRE3
Trafficking protein particle complex subunit 11

1

3

High-throughput

0.437

High

1320880

D2MP
Matrix metalloproteinase-2

1

3

High-throughput

0.437

High

1321637

DRC4
Dynein regulatory complex subunit 4

1

2

High-throughput

0.437

High

1344945

Q8SZX1
CG7387 protein

1

3

High-throughput

0.437

High

1345899

Q8T465
AT13777p

1

1

High-throughput

0.437

High

1345918

GAP2
Ras GTPase-activating protein raskol

1

4

High-throughput

0.437

High

1378975

Q960G1
tRNA

1

3

High-throughput

0.437

High

1445148

C6A22
Cytochrome P450 6a22

1

1

High-throughput

0.437

High

1445150

SAS6
Spindle assembly abnormal protein 6 homolog

1

6

High-throughput

0.437

High

1445151

Q9VAM5
Bromodomain containing 8

1

18

High-throughput

0.437

High

1445153

Q9VBX5
Tubulin--tyrosine ligase-like protein 5

1

4

High-throughput

0.437

High

1445162

CP6D5
Probable cytochrome P450 6d5

1

1

High-throughput

0.437

High

1445166

Q9VHW5
LD38634p

1

7

High-throughput

0.437

High

1445170

Q9VJ74
Probable ATP-dependent RNA helicase DDX23

1

5

High-throughput

0.437

High

1445172

Q9VJJ9
FI20237p1

1

2

High-throughput

0.437

High

1445178

Q9VN21
LD30155p

1

3

High-throughput

0.437

High

1445188

INP5E
Inositol polyphosphate 5-phosphatase E

1

1

High-throughput

0.437

High

1445198

NNAD
Cytosolic carboxypeptidase Nna1

1

4

High-throughput

0.437

High

1445213

R9PY49
Uncharacterized protein, isoform C

1

4

High-throughput

0.437

High

1445214

X2JG79
Supervillin, isoform W

1

2

High-throughput

0.437

High

628926

TFS2
Transcription elongation factor S-II

1

0

High-throughput

0.426

High

94976

E1JGP0
LD04994p1

1

5

High-throughput

0.417

High

263765

O61674
Faint sausage

1

3

High-throughput

0.417

High

1285348

Q86B44
Glutathione synthetase

1

1

High-throughput

0.417

High

1378246

Q95TK6
LD44304p

1

5

High-throughput

0.417

High

1378875

Q960D5
Zinc finger CCHC domain-containing protein 7

1

1

High-throughput

0.417

High

1440722

Q9I7T8
PAN2-PAN3 deadenylation complex subunit PAN3

1

2

High-throughput

0.417

High

1445199

Q9VYF9
RE28286p

1

8

High-throughput

0.417

High

118983

M9NFI9
Neurabin-1

1

5

High-throughput

0.407

High

1175034

NETB
Netrin-B

1

1

High-throughput

0.407

High

1445196

Q9VVT4
IP10578p

2

0

High-throughput

0.310

High

1445177

Q9VMP7
Uncharacterized protein

1

0

High-throughput

0.282

High

234865

O46070
EG:25E8.4 protein

1

0

High-throughput

0.265

Low

1445185

Q9VRQ4
LD47944p

1

0

High-throughput

0.265

Low

54714

A1Z8V7
FI16532p1

1

0

High-throughput

0.249

Low

95104

E1JHG4
Uncharacterized protein, isoform C

1

0

High-throughput

0.249

Low

122304

M9PI43
Centriolar coiled coil protein 110kDa, isoform F

1

0

High-throughput

0.249

Low

551681

ITA2
Integrin alpha-PS2

1

0

High-throughput

0.249

Low

1010838

TIDC1
Complex I assembly factor TIMMDC1, mitochondrial

1

0

High-throughput

0.249

Low

1261456

Q7JQU5
AT09333p

1

0

High-throughput

0.249

Low

1262095

CEP89
Protein Cep89 homolog

1

0

High-throughput

0.249

Low

1285648

Q86BL9
Uncharacterized protein

1

0

High-throughput

0.249

Low

1344964

ICE2
Little elongation complex subunit 2

1

0

High-throughput

0.249

Low

1345926

Q8T4A3
AT08308p

1

0

High-throughput

0.249

Low

1355809

FDL
Probable beta-hexosaminidase fdl

1

0

High-throughput

0.249

Low

1377150

Q95R73
SD03412p

1

0

High-throughput

0.249

Low

1445139

TO401
Mitochondrial import receptor subunit TOM40 homolog 1

1

0

High-throughput

0.249

Low

1445140

HEM6
Oxygen-dependent coproporphyrinogen-III oxidase

1

0

High-throughput

0.249

Low

1445141

MTTF
Transcription termination factor, mitochondrial

1

0

High-throughput

0.249

Low

1445156

Q9VDC2
isopentenyl-diphosphate Delta-isomerase

1

0

High-throughput

0.249

Low

1445158

HMW
Protein hemingway

1

0

High-throughput

0.249

Low

1445160

Q9VFF6
FI21290p1

1

0

High-throughput

0.249

Low

1445164

Q9VGZ4
LD10232p

1

0

High-throughput

0.249

Low

1445165

Q9VHL9
AT23003p

1

0

High-throughput

0.249

Low

1445168

Q9VI32
Dynein regulatory complex protein 10

1

0

High-throughput

0.249

Low

1445195

Q9VVH8
MIP08660p

1

0

High-throughput

0.249

Low

1445202

Q9VZE0
Dusky-like, isoform A

1

0

High-throughput

0.249

Low

1445206

NDNF
Protein NDNF

1

0

High-throughput

0.249

Low

1445208

Q9W3G9
Companion of reaper protein

1

0

Small-scale

0.249

Low

1445210

Q9W3S0
GH24548p

1

0

High-throughput

0.249

Low

1445211

Q9W547
Large ribosomal subunit protein uL16m

1

0

High-throughput

0.249

Low

1445183

Q9VRB7
GH11587p

1

0

High-throughput

0.238

Low

1069341

Q0E8K5
AT10158p

1

0

High-throughput

0.232

Low

1263363

Q7JYP4
AT30334p

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025