Protein: PUR1
Amidophosphoribosyltransferase (ATase) (EC 2.4.2.14) (Glutamine phosphoribosylpyrophosphate amidotransferase) (GPAT)

Gene: PUR1, PPAT
Organism: Homo sapiens
Interactions: 38
UniProt ID: Q06203

Gene Ontology (top 5):
GO:0004044 - amidophosphoribosyltransferase activity
GO:0005829 - cytosol
GO:0006164 - purine nucleotide biosynthetic process
GO:0006177 - GMP biosynthetic process
GO:0006189 - 'de novo' IMP biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

986467

NUDT5
ADP-sugar pyrophosphatase

3

0

High-throughput

0.634

High

986458

MMS19
MMS19 nucleotide excision repair protein homolog

3

1

Small-scale

0.633

High

901865

B2MG
Beta-2-microglobulin [Cleaved into: Beta-2-microglobulin form pI 5.3]

2

2

High-throughput

0.628

High

227247

PRKN
E3 ubiquitin-protein ligase parkin

2

7

High-throughput

0.584

High

986464

SMUF1
E3 ubiquitin-protein ligase SMURF1

2

1

High-throughput

0.584

High

986468

CIA2B
Cytosolic iron-sulfur assembly component 2B

2

0

Small-scale

0.547

High

868446

ATX1
Ataxin-1

1

3

High-throughput

0.541

High

986461

EPT1
Ethanolaminephosphotransferase 1

1

0

High-throughput

0.518

High

174820

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

2

High-throughput

0.501

High

177271

HDAC3
Histone deacetylase 3

1

3

High-throughput

0.479

High

294740

RECQ4
ATP-dependent DNA helicase Q4

1

2

High-throughput

0.479

High

322513

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

1

High-throughput

0.479

High

651024

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.479

High

779285

CCNF
Cyclin-F

1

3

High-throughput

0.479

High

908421

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

2

High-throughput

0.479

High

986451

CUL3
Cullin-3

1

5

High-throughput

0.479

High

986459

ANM1
Protein arginine N-methyltransferase 1

1

2

High-throughput

0.479

High

986463

EGLN3
Prolyl hydroxylase EGLN3

1

1

High-throughput

0.479

High

986465

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

986466

FBW1B
F-box/WD repeat-containing protein 11

1

4

High-throughput

0.479

High

509229

G6PD
Glucose-6-phosphate 1-dehydrogenase

1

0

High-throughput

0.458

High

986453

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

3

High-throughput

0.445

High

986457

OTUB1
Ubiquitin thioesterase OTUB1

1

1

High-throughput

0.445

High

282884

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

1

4

High-throughput

0.437

High

384698

NTRK1
High affinity nerve growth factor receptor

1

7

High-throughput

0.437

High

552558

RFA2
Replication protein A 32 kDa subunit

1

3

High-throughput

0.437

High

718781

PHB1
Prohibitin 1

1

2

High-throughput

0.437

High

720292

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.437

High

986455

TRI67
Tripartite motif-containing protein 67

1

5

High-throughput

0.437

High

986456

ESR2
Estrogen receptor beta

1

3

High-throughput

0.437

High

986462

PKHA4
Pleckstrin homology domain-containing family A member 4

1

4

High-throughput

0.437

High

382399

HLAA
HLA class I histocompatibility antigen, A alpha chain

1

1

High-throughput

0.407

High

986460

ZDHC5
Palmitoyltransferase ZDHHC5

1

2

High-throughput

0.407

High

831254

CEBPA
CCAAT/enhancer-binding protein alpha

1

2

High-throughput

0.373

High

118282

HAX1
HCLS1-associated protein X-1

1

0

High-throughput

0.249

Low

953146

CCZ1B
Vacuolar fusion protein CCZ1 homolog B

1

0

High-throughput

0.249

Low

986452

CRY1
Cryptochrome-1

1

0

High-throughput

0.249

Low

986454

TET5C
Terminal nucleotidyltransferase 5C

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024