Protein: CDKN3
Cyclin-dependent kinase inhibitor 3 (EC 3.1.3.16) (EC 3.1.3.48) (CDK2-associated dual-specificity phosphatase) (Cyclin-dependent kinase interactor 1) (Cyclin-dependent kinase-interacting protein 2) (Kinase-associated phosphatase)

Gene: CDKN3
Organism: Homo sapiens
Interactions: 55
UniProt ID: Q16667

Gene Ontology (top 5):
GO:0000079 - regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0000082 - G1/S transition of mitotic cell cycle
GO:0004722 - protein serine/threonine phosphatase activity
GO:0004725 - protein tyrosine phosphatase activity
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

625470

CDK2
Cyclin-dependent kinase 2

12

2

Small-scale

0.982

High

414938

CDK1
Cyclin-dependent kinase 1

5

2

Small-scale

0.927

High

960097

CDK3
Cyclin-dependent kinase 3

2

2

Small-scale

0.747

High

254484

ROCK2
Rho-associated protein kinase 2

1

2

Small-scale

0.724

High

1035176

ROCK1
Rho-associated protein kinase 1

1

2

Small-scale

0.618

High

1086089

MRCKB
Serine/threonine-protein kinase MRCK beta

1

2

Small-scale

0.618

High

1086067

CDKN3
Cyclin-dependent kinase inhibitor 3

1

0

High-throughput

0.586

High

122029

PSD12
26S proteasome non-ATPase regulatory subunit 12

2

0

Small-scale

0.559

High

1086083

RMD5A
E3 ubiquitin-protein transferase RMND5A

2

0

Small-scale

0.559

High

1086078

MS4A3
Membrane-spanning 4-domains subfamily A member 3

1

0

Small-scale

0.529

High

238488

CST8
Cystatin-8

1

0

High-throughput

0.513

High

562932

STMN1
Stathmin

1

0

High-throughput

0.513

High

749543

BRCA1
Breast cancer type 1 susceptibility protein

1

0

High-throughput

0.513

High

841467

BPL1
Biotin--protein ligase

1

0

High-throughput

0.513

High

873131

PTN5
Tyrosine-protein phosphatase non-receptor type 5

1

0

High-throughput

0.513

High

1018975

TP53B
TP53-binding protein 1

1

0

High-throughput

0.513

High

1033947

XRCC4
DNA repair protein XRCC4

1

0

High-throughput

0.513

High

1086068

2ABD
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform

1

0

High-throughput

0.513

High

1086071

HORN
Hornerin

1

0

High-throughput

0.513

High

1086072

KIBRA
Protein KIBRA

1

0

High-throughput

0.513

High

1086074

JMY
Junction-mediating and -regulatory protein

1

0

High-throughput

0.513

High

1086077

ARK2N
Protein ARK2N

1

0

High-throughput

0.513

High

1086088

BI2L1
BAR/IMD domain-containing adapter protein 2-like 1

1

0

High-throughput

0.513

High

751648

GRP75
Stress-70 protein, mitochondrial

1

0

High-throughput

0.493

High

161378

MYPT1
Protein phosphatase 1 regulatory subunit 12A

1

0

Small-scale

0.480

High

572971

PRS6A
26S proteasome regulatory subunit 6A

1

2

High-throughput

0.479

High

798679

PRS6B
26S proteasome regulatory subunit 6B

1

2

High-throughput

0.479

High

872168

RD23A
UV excision repair protein RAD23 homolog A

1

2

High-throughput

0.479

High

872274

RD23B
UV excision repair protein RAD23 homolog B

1

1

High-throughput

0.479

High

906843

PRS4
26S proteasome regulatory subunit 4

1

2

High-throughput

0.479

High

913281

PRS10
26S proteasome regulatory subunit 10B

1

2

High-throughput

0.479

High

1086090

NCOA3
Nuclear receptor coactivator 3

1

0

Small-scale

0.460

High

575459

EGR1
Early growth response protein 1

1

0

High-throughput

0.458

High

717874

BMI1
Polycomb complex protein BMI-1

1

0

Small-scale

0.458

High

803558

BAG6
Large proline-rich protein BAG6

1

0

High-throughput

0.458

High

829178

SYAC
Alanine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.458

High

855486

MSH6
DNA mismatch repair protein Msh6

1

0

High-throughput

0.458

High

966707

PFKAP
ATP-dependent 6-phosphofructokinase, platelet type

1

0

High-throughput

0.458

High

1086073

ARG28
Rho guanine nucleotide exchange factor 28

1

0

High-throughput

0.458

High

1086075

IPO4
Importin-4

1

0

High-throughput

0.458

High

1086076

DI3L1
DIS3-like exonuclease 1

1

0

High-throughput

0.458

High

1086079

NP1L4
Nucleosome assembly protein 1-like 4

1

0

High-throughput

0.458

High

1086081

CLPB
Mitochondrial disaggregase

1

0

High-throughput

0.458

High

1086082

UN45A
Protein unc-45 homolog A

1

0

High-throughput

0.458

High

1086085

GOPC
Golgi-associated PDZ and coiled-coil motif-containing protein

1

0

High-throughput

0.458

High

1086086

ATX10
Ataxin-10

1

0

High-throughput

0.458

High

996238

CD47
Leukocyte surface antigen CD47

1

0

High-throughput

0.279

Low

1086069

BOP
Protein Bop

1

0

High-throughput

0.279

Low

1086070

R3HCL
Coiled-coil domain-containing protein R3HCC1L

1

0

High-throughput

0.279

Low

1086084

NOL11
Nucleolar protein 11

1

0

High-throughput

0.279

Low

118329

HAX1
HCLS1-associated protein X-1

1

0

High-throughput

0.249

Low

489753

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

1

0

High-throughput

0.249

Low

1086080

HDHD5
Haloacid dehalogenase-like hydrolase domain-containing 5

1

0

High-throughput

0.249

Low

1086087

SEC63
Translocation protein SEC63 homolog

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024