Protein: PTPRN
Receptor-type tyrosine-protein phosphatase-like N (R-PTP-N) (Islet cell antigen 512) (ICA 512) (Islet cell autoantigen 3) (PTP IA-2) [Cleaved into: ICA512-N-terminal fragment (ICA512-NTF); ICA512-transmembrane fragment (ICA512-TMF); ICA512-cleaved cytosolic fragment (ICA512-CCF)]

Gene: PTPRN
Organism: Homo sapiens
Interactions: 119
UniProt ID: Q16849

Gene Ontology (top 5):
GO:0000302 - response to reactive oxygen species
GO:0001553 - luteinization
GO:0005634 - nucleus
GO:0005768 - endosome
GO:0005794 - Golgi apparatus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1088220

PTPR2
Receptor-type tyrosine-protein phosphatase N2

2

19

High-throughput

0.811

High

1031991

PTPRS
Receptor-type tyrosine-protein phosphatase S

1

17

Small-scale

0.740

High

1088196

PTPRN
Receptor-type tyrosine-protein phosphatase-like N

2

18

Small-scale

0.726

High

888255

MYPR
Myelin proteolipid protein

6

0

High-throughput

0.711

High

1088202

TM214
Transmembrane protein 214

3

1

High-throughput

0.667

High

146928

PTPRT
Receptor-type tyrosine-protein phosphatase T

1

19

Small-scale

0.653

High

1088219

SNX19
Sorting nexin-19

2

2

Small-scale

0.631

High

297756

MICA2
[F-actin]-monooxygenase MICAL2

2

6

High-throughput

0.628

High

673958

HLAF
HLA class I histocompatibility antigen, alpha chain F

2

2

High-throughput

0.628

High

1033877

SNTB2
Beta-2-syntrophin

2

14

Small-scale

0.625

High

502159

BIP
Endoplasmic reticulum chaperone BiP

2

8

High-throughput

0.611

High

816578

CXA8
Gap junction alpha-8 protein

2

9

High-throughput

0.606

High

1088214

GP152
Probable G-protein coupled receptor 152

2

11

High-throughput

0.606

High

1058436

GANAB
Neutral alpha-glucosidase AB

2

4

High-throughput

0.584

High

1067719

PDIA6
Protein disulfide-isomerase A6

2

18

High-throughput

0.584

High

1023417

TRDN
Triadin

2

0

High-throughput

0.580

High

1088238

CC134
Coiled-coil domain-containing protein 134

2

0

High-throughput

0.580

High

195601

SGSM2
Small G protein signaling modulator 2

2

5

High-throughput

0.574

High

1088216

NEUFC
Neuferricin

2

5

High-throughput

0.574

High

923696

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

2

Small-scale

0.573

High

1088217

MADD
MAP kinase-activating death domain protein

1

6

Small-scale

0.573

High

1088237

SPTN4
Spectrin beta chain, non-erythrocytic 4

1

4

Small-scale

0.573

High

1088226

TMM80
Transmembrane protein 80

2

2

High-throughput

0.553

High

1088241

TIDC1
Complex I assembly factor TIMMDC1, mitochondrial

2

1

High-throughput

0.553

High

118960

KCNK1
Potassium channel subfamily K member 1

1

1

High-throughput

0.536

High

152293

ADA10
Disintegrin and metalloproteinase domain-containing protein 10

1

4

High-throughput

0.536

High

233065

FZD6
Frizzled-6

1

3

High-throughput

0.536

High

259525

SEM7A
Semaphorin-7A

1

1

High-throughput

0.536

High

1088198

HFE
Hereditary hemochromatosis protein

1

5

High-throughput

0.536

High

1088227

KI16B
Kinesin-like protein KIF16B

1

8

High-throughput

0.536

High

1088233

LRFN3
Leucine-rich repeat and fibronectin type-III domain-containing protein 3

1

12

High-throughput

0.536

High

1088244

IMPA3
Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase

1

1

High-throughput

0.536

High

423244

PDIA1
Protein disulfide-isomerase

2

15

High-throughput

0.533

High

531847

PDIA4
Protein disulfide-isomerase A4

2

17

High-throughput

0.533

High

654377

CALX
Calnexin

2

10

High-throughput

0.533

High

1088242

UBQL4
Ubiquilin-4

1

6

High-throughput

0.508

High

253568

CAPON
Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein

1

11

Small-scale

0.501

High

568982

CAN2
Calpain-2 catalytic subunit

1

2

Small-scale

0.501

High

1045075

LAMB3
Laminin subunit beta-3

1

6

High-throughput

0.489

High

1072682

UBE3C
Ubiquitin-protein ligase E3C

1

10

High-throughput

0.489

High

1088200

RETST
All-trans-retinol 13,14-reductase

1

1

High-throughput

0.489

High

1088207

FRMD5
FERM domain-containing protein 5

1

7

High-throughput

0.489

High

1088230

CP2S1
Cytochrome P450 2S1

1

1

High-throughput

0.489

High

1088255

DJC16
DnaJ homolog subfamily C member 16

1

20

High-throughput

0.489

High

1088256

MAN1
Inner nuclear membrane protein Man1

1

3

High-throughput

0.489

High

127281

IPO5
Importin-5

1

10

High-throughput

0.479

High

199340

ZW10
Centromere/kinetochore protein zw10 homolog

1

1

High-throughput

0.479

High

216242

CALU
Calumenin

1

2

High-throughput

0.479

High

236423

RNBP6
Ran-binding protein 6

1

10

High-throughput

0.479

High

237065

PLOD3
Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 [Includes: Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3

1

4

High-throughput

0.479

High

256754

CAND2
Cullin-associated NEDD8-dissociated protein 2

1

13

High-throughput

0.479

High

538254

ENPL
Endoplasmin

1

2

High-throughput

0.479

High

614338

PPIB
Peptidyl-prolyl cis-trans isomerase B

1

2

High-throughput

0.479

High

653610

CALR
Calreticulin

1

10

High-throughput

0.479

High

671826

PDIA3
Protein disulfide-isomerase A3

1

16

High-throughput

0.479

High

762998

OST48
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

1

1

High-throughput

0.479

High

777190

PEX19
Peroxisomal biogenesis factor 19

1

1

High-throughput

0.479

High

874520

XPO2
Exportin-2

1

17

High-throughput

0.479

High

1066184

KIF14
Kinesin-like protein KIF14

1

10

High-throughput

0.479

High

1088203

LMBRL
Protein LMBR1L

1

2

High-throughput

0.479

High

1088204

DYM
Dymeclin

1

1

High-throughput

0.479

High

1088213

CIP2A
Protein CIP2A

1

3

High-throughput

0.479

High

1088218

S39A7
Zinc transporter SLC39A7

1

7

High-throughput

0.479

High

1088221

TNPO1
Transportin-1

1

18

High-throughput

0.479

High

1088223

ASTRA
Protein Aster-A

1

3

High-throughput

0.479

High

1088224

SAAL1
Protein SAAL1

1

2

High-throughput

0.479

High

1088229

XPO6
Exportin-6

1

1

High-throughput

0.479

High

1088235

XPO4
Exportin-4

1

9

High-throughput

0.479

High

1088236

TTYH3
Protein tweety homolog 3

1

1

High-throughput

0.479

High

1088240

XPO5
Exportin-5

1

18

High-throughput

0.479

High

1088248

ATX10
Ataxin-10

1

2

High-throughput

0.479

High

1088249

NCDN
Neurochondrin

1

1

High-throughput

0.479

High

1088251

DJB11
DnaJ homolog subfamily B member 11

1

2

High-throughput

0.479

High

1088234

TMM43
Transmembrane protein 43

1

0

High-throughput

0.458

High

1088245

CKLF6
CKLF-like MARVEL transmembrane domain-containing protein 6

1

0

High-throughput

0.458

High

1088250

EIF3K
Eukaryotic translation initiation factor 3 subunit K

1

0

High-throughput

0.458

High

354953

DRB1
HLA class II histocompatibility antigen, DRB1 beta chain

1

5

High-throughput

0.445

High

1047108

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

12

High-throughput

0.445

High

207945

XPOT
Exportin-T

1

19

High-throughput

0.437

High

242855

TRI13
E3 ubiquitin-protein ligase TRIM13

1

4

High-throughput

0.437

High

296919

LTN1
E3 ubiquitin-protein ligase listerin

1

2

High-throughput

0.437

High

335823

COX2
Cytochrome c oxidase subunit 2

1

1

High-throughput

0.437

High

390921

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

2

High-throughput

0.437

High

536374

GLU2B
Glucosidase 2 subunit beta

1

3

High-throughput

0.437

High

901480

S61A1
Protein transport protein Sec61 subunit alpha isoform 1

1

4

High-throughput

0.437

High

972753

PLOD1
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1

1

4

High-throughput

0.437

High

1088199

TGO1
Transport and Golgi organization protein 1 homolog

1

5

High-throughput

0.437

High

1088201

RINT1
RAD50-interacting protein 1

1

2

High-throughput

0.437

High

1088205

MON2
Protein MON2 homolog

1

4

High-throughput

0.437

High

1088206

HEAT3
HEAT repeat-containing protein 3

1

1

High-throughput

0.437

High

1088208

DAAF5
Dynein axonemal assembly factor 5

1

1

High-throughput

0.437

High

1088209

GT251
Procollagen galactosyltransferase 1

1

4

High-throughput

0.437

High

1088210

TXND5
Thioredoxin domain-containing protein 5

1

18

High-throughput

0.437

High

1088212

TBC15
TBC1 domain family member 15

1

5

High-throughput

0.437

High

1088215

PO210
Nuclear pore membrane glycoprotein 210

1

1

High-throughput

0.437

High

1088232

ERP44
Endoplasmic reticulum resident protein 44

1

18

High-throughput

0.437

High

1088239

S61A2
Protein transport protein Sec61 subunit alpha isoform 2

1

4

High-throughput

0.437

High

1088246

UGGG1
UDP-glucose:glycoprotein glucosyltransferase 1

1

3

High-throughput

0.437

High

1088253

CS025
UPF0449 protein C19orf25

1

2

High-throughput

0.437

High

1088257

HYOU1
Hypoxia up-regulated protein 1

1

9

High-throughput

0.437

High

1088258

TNPO3
Transportin-3

1

20

High-throughput

0.437

High

1088259

5MP1
eIF5-mimic protein 1

1

1

High-throughput

0.437

High

1024129

PAFA
Platelet-activating factor acetylhydrolase

3

0

High-throughput

0.345

High

1088211

MFSD8
Major facilitator superfamily domain-containing protein 8

2

0

High-throughput

0.328

High

1088225

MITOK
Mitochondrial potassium channel

2

0

High-throughput

0.328

High

1088231

ADPGK
ADP-dependent glucokinase

2

0

High-throughput

0.328

High

174210

SPTC2
Serine palmitoyltransferase 2

2

0

High-throughput

0.318

High

596890

MAL
Myelin and lymphocyte protein

1

0

High-throughput

0.299

High

554820

TIMP2
Metalloproteinase inhibitor 2

1

0

High-throughput

0.279

Low

1088197

ALG11
GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase

1

0

High-throughput

0.279

Low

1088222

RFT1
Man(5)GlcNAc(2)-PP-dolichol translocation protein RFT1

1

0

High-throughput

0.279

Low

1088228

DIESL
DGAT1/2-independent enzyme synthesizing storage lipids

1

0

High-throughput

0.279

Low

1088254

METRN
Meteorin

1

0

High-throughput

0.279

Low

1088252

CLN8
Protein CLN8

1

0

Small-scale

0.251

Low

215449

SCO2
Protein SCO2 homolog, mitochondrial

1

0

High-throughput

0.249

Low

1034457

OS9
Protein OS-9

1

0

High-throughput

0.249

Low

1088243

CLN6
Ceroid-lipofuscinosis neuronal protein 6

1

0

High-throughput

0.249

Low

1088247

CNIH4
Protein cornichon homolog 4

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024