Protein: TMLH
Trimethyllysine dioxygenase, mitochondrial (EC 1.14.11.8) (Epsilon-trimethyllysine 2-oxoglutarate dioxygenase) (Epsilon-trimethyllysine hydroxylase) (TML hydroxylase) (TML-alpha-ketoglutarate dioxygenase) (TML dioxygenase) (TMLD)

Gene: TMLH, TMLHE
Organism: Homo sapiens
Interactions: 64
UniProt ID: Q9NVH6

Gene Ontology (top 5):
GO:0005506 - iron ion binding
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0045329 - carnitine biosynthetic process
GO:0050353 - trimethyllysine dioxygenase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1346585

TMLH
Trimethyllysine dioxygenase, mitochondrial

1

2

Small-scale

0.647

High

1086822

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

2

0

Small-scale

0.559

High

259477

NIPS2
Protein NipSnap homolog 2

1

2

High-throughput

0.536

High

646467

KAD4
Adenylate kinase 4, mitochondrial

1

1

High-throughput

0.536

High

1297477

IMP1L
Mitochondrial inner membrane protease subunit 1

1

1

High-throughput

0.536

High

1310967

NPS3B
Protein NipSnap homolog 3B

1

2

High-throughput

0.536

High

1346590

NPS3A
Protein NipSnap homolog 3A

1

2

High-throughput

0.536

High

258813

NDUS7
NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial

1

0

High-throughput

0.513

High

272394

MTU1
Mitochondrial tRNA-specific 2-thiouridylase 1

1

0

High-throughput

0.513

High

782862

PLPL4
Patatin-like phospholipase domain-containing protein 4

1

0

High-throughput

0.513

High

790284

THIM
3-ketoacyl-CoA thiolase, mitochondrial

1

0

High-throughput

0.513

High

815456

UCRI
Cytochrome b-c1 complex subunit Rieske, mitochondrial

1

0

High-throughput

0.513

High

1030127

DHRS2
Dehydrogenase/reductase SDR family member 2, mitochondrial

1

0

High-throughput

0.513

High

1156331

ACSM5
Acyl-coenzyme A synthetase ACSM5, mitochondrial

1

0

High-throughput

0.513

High

1157987

RUSD3
Mitochondrial mRNA pseudouridine synthase RPUSD3

1

0

High-throughput

0.513

High

1159947

FAHD1
Oxaloacetate decarboxylase, mitochondrial

1

0

High-throughput

0.513

High

1221265

ETKMT
Electron transfer flavoprotein beta subunit lysine methyltransferase

1

0

High-throughput

0.513

High

1312687

MYL10
Myosin regulatory light chain 10

1

0

High-throughput

0.513

High

1312786

ISCA1
Iron-sulfur cluster assembly 1 homolog, mitochondrial

1

0

High-throughput

0.513

High

1316345

SCOT2
Succinyl-CoA:3-ketoacid coenzyme A transferase 2, mitochondrial

1

0

High-throughput

0.513

High

1317619

LDH6B
L-lactate dehydrogenase A-like 6B

1

0

High-throughput

0.513

High

1346589

DIC
Mitochondrial dicarboxylate carrier

1

0

High-throughput

0.513

High

1346591

AMACR
Alpha-methylacyl-CoA racemase

1

0

High-throughput

0.513

High

1346592

MRM2
rRNA methyltransferase 2, mitochondrial

1

0

High-throughput

0.513

High

1346595

SYYM
Tyrosine--tRNA ligase, mitochondrial

1

0

High-throughput

0.513

High

1346597

RT02
Small ribosomal subunit protein uS2m

1

0

High-throughput

0.513

High

440763

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

1

High-throughput

0.479

High

500154

CH60
60 kDa heat shock protein, mitochondrial

1

1

High-throughput

0.479

High

1138605

SDHF4
Succinate dehydrogenase assembly factor 4, mitochondrial

1

0

High-throughput

0.458

High

1346492

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

0

High-throughput

0.458

High

1302862

IMP2L
Mitochondrial inner membrane protease subunit 2

1

1

High-throughput

0.437

High

1036937

SQSTM
Sequestosome-1

1

0

High-throughput

0.426

High

1051113

ICT1
Large ribosomal subunit protein mL62

1

0

High-throughput

0.426

High

1346588

STIM2
Stromal interaction molecule 2

2

0

High-throughput

0.328

High

147814

G3PT
Glyceraldehyde-3-phosphate dehydrogenase, testis-specific

1

0

High-throughput

0.279

Low

243633

DNJA2
DnaJ homolog subfamily A member 2

1

0

High-throughput

0.279

Low

724469

PCKGC
Phosphoenolpyruvate carboxykinase, cytosolic [GTP]

1

0

High-throughput

0.279

Low

957135

SHC2
SHC-transforming protein 2

1

0

High-throughput

0.279

Low

1253041

F174A
Membrane protein FAM174A

1

0

High-throughput

0.279

Low

1259574

SRB4D
Scavenger receptor cysteine-rich domain-containing group B protein

1

0

High-throughput

0.279

Low

1285829

TRI43
Tripartite motif-containing protein 43

1

0

High-throughput

0.279

Low

1288535

ARHGQ
Rho guanine nucleotide exchange factor 26

1

0

High-throughput

0.279

Low

1289899

RT24
Small ribosomal subunit protein uS3m

1

0

High-throughput

0.279

Low

1301894

RSLAB
Ras-like protein family member 10B

1

0

High-throughput

0.279

Low

1309935

LSMD1
N-alpha-acetyltransferase 38, NatC auxiliary subunit

1

0

High-throughput

0.279

Low

1346593

DNPEP
Aspartyl aminopeptidase

1

0

High-throughput

0.279

Low

1346594

RT17
Small ribosomal subunit protein uS17m

1

0

High-throughput

0.279

Low

1346596

KLK5
Kallikrein-5

1

0

High-throughput

0.279

Low

1346598

GPR45
Probable G-protein coupled receptor 45

1

0

High-throughput

0.279

Low

1051199

BTG3
Protein BTG3

1

0

High-throughput

0.269

Low

119539

LEG9
Galectin-9

1

0

High-throughput

0.249

Low

125747

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

0

Small-scale

0.249

Low

262599

TULP3
Tubby-related protein 3

1

0

High-throughput

0.249

Low

830485

KC1E
Casein kinase I isoform epsilon

1

0

High-throughput

0.249

Low

929259

RS21
Small ribosomal subunit protein eS21

1

0

High-throughput

0.249

Low

1042646

CUL3
Cullin-3

1

0

High-throughput

0.249

Low

1101330

CL16A
Protein CLEC16A

1

0

High-throughput

0.249

Low

1171945

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

402532

JUN
Transcription factor Jun

1

0

High-throughput

0.232

Low

997140

RBL2
Retinoblastoma-like protein 2

1

0

Small-scale

0.232

Low

1312300

MED10
Mediator of RNA polymerase II transcription subunit 10

1

0

High-throughput

0.232

Low

1346586

MED9
Mediator of RNA polymerase II transcription subunit 9

1

0

High-throughput

0.232

Low

1346587

MED29
Mediator of RNA polymerase II transcription subunit 29

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024