Protein: BIP
Endoplasmic reticulum chaperone BiP (EC 3.6.4.10) (78 kDa glucose-regulated protein homolog) (GRP-78 homolog) (Binding-immunoglobulin protein homolog) (BiP) (Heat shock 70 kDa protein cognate 3) (Heat shock protein cognate 72)

Gene: BIP, Hsc70-3
Organism: Drosophila melanogaster
Interactions: 59
UniProt ID: P29844

Gene Ontology (top 5):
GO:0005524 - ATP binding
GO:0005615 - extracellular space
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005783 - endoplasmic reticulum

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

715363

FICD
Protein adenylyltransferase Fic

2

2

Small-scale

0.778

High

56196

A1ZA03
Pms2

1

2

High-throughput

0.621

High

715369

Q9V3E9
RNA polymerase II-associated protein 3

1

20

Small-scale

0.618

High

303851

O76417
MutL homolog PMS2

1

2

High-throughput

0.590

High

715349

FAS2
Fasciclin-2

1

0

High-throughput

0.513

High

52293

A1Z6R4
Serpin 42Dc, isoform A

1

10

High-throughput

0.508

High

715377

Q9VM98
AT06841p1

1

0

High-throughput

0.486

High

94227

D5SHR3
HECT-type E3 ubiquitin transferase

1

13

High-throughput

0.481

High

68893

MBD56
Methyl-CpG-binding domain protein 5/6 homolog sba

1

1

High-throughput

0.479

High

120279

M9PD17
Gigas, isoform B

1

1

High-throughput

0.479

High

304932

CRY1
Cryptochrome-1

1

3

High-throughput

0.479

High

594785

GNAO
G protein alpha o subunit

1

7

Small-scale

0.479

High

654203

DDX6
ATP-dependent RNA helicase me31b

1

8

High-throughput

0.479

High

715350

P91634
phosphatidylinositol 3-kinase

1

2

High-throughput

0.479

High

715351

SIMA
Protein similar

1

9

High-throughput

0.479

High

715353

YAP1
Transcriptional coactivator yorkie

1

18

High-throughput

0.479

High

715356

Q7K4C2
LD46713p

1

3

High-throughput

0.479

High

715358

Q7KMQ6
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

6

High-throughput

0.479

High

715360

AKT1
RAC serine/threonine-protein kinase

1

19

High-throughput

0.479

High

715361

CASP8
Caspase-8

1

7

Small-scale

0.479

High

715364

Q8T9L5
Serine/threonine-protein kinase STK11

1

17

High-throughput

0.479

High

715365

Q94533
Ribosomal protein S6 kinase

1

17

High-throughput

0.479

High

715366

FOXO
Forkhead box protein O

1

5

High-throughput

0.479

High

715370

ATLAS
Atlastin

1

7

Small-scale

0.479

High

715371

Q9VCC9
LD23779p

1

15

High-throughput

0.479

High

715372

Q9VDI1
LD46328p

1

4

High-throughput

0.479

High

715373

IKKB
Inhibitor of nuclear factor kappa-B kinase subunit beta

1

16

High-throughput

0.479

High

715380

Q9VR61
non-specific serine/threonine protein kinase

1

17

High-throughput

0.479

High

715382

PYRG
CTP synthase

1

3

High-throughput

0.479

High

715383

OSGEP
Probable tRNA N6-adenosine threonylcarbamoyltransferase

1

1

High-throughput

0.479

High

715386

PDPK1
3-phosphoinositide-dependent protein kinase 1

1

20

High-throughput

0.479

High

715390

MYC
Myc proto-oncogene protein

1

9

High-throughput

0.479

High

715391

IRS1
Insulin receptor substrate 1

1

3

High-throughput

0.479

High

95335

E1JIQ5
Exit protein of rhodopsin and TRP B, isoform A

1

0

Small-scale

0.458

High

715392

4EBP
Eukaryotic translation initiation factor 4E-binding protein

1

0

High-throughput

0.458

High

715387

Q9W326
HECT-type E3 ubiquitin transferase

1

15

High-throughput

0.457

High

715355

Q7JZT9
allantoinase

1

7

High-throughput

0.445

High

715374

Q9VFX0
Aminopeptidase

1

5

High-throughput

0.445

High

715388

Q9W478
RE43153p

1

6

High-throughput

0.445

High

58158

A1ZBG4
Uncharacterized protein, isoform E

1

1

High-throughput

0.439

High

119565

M9PAY7
Pi3K21B, isoform C

1

20

High-throughput

0.437

High

438046

OPS1
Opsin Rh1

1

2

Small-scale

0.437

High

715354

Q6NQZ7
LD40663p

1

2

High-throughput

0.437

High

715357

IMD
Protein immune deficiency

1

1

High-throughput

0.437

High

715359

Q7KNQ9
Connector enhancer of KSR protein CNK

1

7

High-throughput

0.437

High

715362

Q8MRA3
Hibris, isoform A

1

5

High-throughput

0.437

High

715367

Q9I7M5
Cell division cycle protein 26 homolog

1

1

High-throughput

0.437

High

715368

Q9NGK5
FI21425p1

1

4

Small-scale

0.437

High

715379

RHEB
GTP-binding protein Rheb homolog

1

13

High-throughput

0.437

High

715384

Q9VWJ6
FI03615p

1

2

High-throughput

0.437

High

715385

PGPLE
Peptidoglycan-recognition protein LE

1

4

High-throughput

0.437

High

58210

A1ZBG6
Uncharacterized protein, isoform C

1

1

High-throughput

0.417

High

715352

RPR
Cell death protein rpr

1

0

High-throughput

0.282

High

715376

Q9VJX3
B4, isoform A

1

0

High-throughput

0.249

Low

715381

MELT
Protein melted

1

0

High-throughput

0.249

Low

715389

Q9W4L9
IP04124p

1

0

High-throughput

0.249

Low

52082

A1Z6M0
Brahma associated protein 170kD

1

0

Small-scale

0.232

Low

715375

Q9VIC3
carboxylesterase

1

0

High-throughput

0.232

Low

715378

GUAD
Guanine deaminase

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025