Protein: NFIC
Nuclear factor 1 C-type (NF1-C) (Nuclear factor 1/C) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/C) (NF-I/C) (NFI-C) (TGGCA-binding protein)

Gene: NFIC
Organism: Homo sapiens
Interactions: 194
UniProt ID: P08651

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

135065

NFIB
Nuclear factor 1 B-type

5

14

Small-scale

0.924

High

443114

NFIC
Nuclear factor 1 C-type

2

13

Small-scale

0.768

High

443177

NFIA
Nuclear factor 1 A-type

1

13

High-throughput

0.691

High

443190

NFIX
Nuclear factor 1 X-type

1

13

High-throughput

0.691

High

421370

TY3H
Tyrosine 3-monooxygenase

4

0

High-throughput

0.669

High

443149

SOX2
Transcription factor SOX-2

2

20

Small-scale

0.634

High

443161

KLF3
Krueppel-like factor 3

2

20

High-throughput

0.624

High

443164

SMAD3
Mothers against decapentaplegic homolog 3

1

5

Small-scale

0.618

High

443115

PARP1
Poly [ADP-ribose] polymerase 1

2

5

Small-scale

0.611

High

443179

FOXC1
Forkhead box protein C1

2

20

High-throughput

0.611

High

345738

MYC
Myc proto-oncogene protein

2

10

High-throughput

0.595

High

443166

TFAP4
Transcription factor AP-4

2

2

Small-scale

0.584

High

443171

TLE3
Transducin-like enhancer protein 3

2

20

High-throughput

0.584

High

443234

CIC
Protein capicua homolog

2

20

High-throughput

0.584

High

211785

TLX3
T-cell leukemia homeobox protein 3

1

20

High-throughput

0.578

High

443128

PAX7
Paired box protein Pax-7

1

20

High-throughput

0.578

High

443129

GATA2
Endothelial transcription factor GATA-2

1

10

High-throughput

0.578

High

443130

GATA3
Trans-acting T-cell-specific transcription factor GATA-3

1

10

High-throughput

0.578

High

443139

SOX5
Transcription factor SOX-5

1

20

High-throughput

0.578

High

443140

SOX6
Transcription factor SOX-6

1

20

High-throughput

0.578

High

443219

SP7
Transcription factor Sp7

1

17

High-throughput

0.578

High

171001

TBXT
T-box transcription factor T

1

11

High-throughput

0.561

High

213291

TLX2
T-cell leukemia homeobox protein 2

1

20

High-throughput

0.561

High

225703

SOX15
Transcription factor SOX-15

1

20

High-throughput

0.561

High

271724

PRDM1
PR domain zinc finger protein 1

1

5

High-throughput

0.561

High

316771

KLF8
Krueppel-like factor 8

1

20

High-throughput

0.561

High

345285

FOS
Protein c-Fos

1

8

High-throughput

0.561

High

443120

ERG
Transcriptional regulator ERG

1

20

High-throughput

0.561

High

443131

TYY1
Transcriptional repressor protein YY1

1

7

High-throughput

0.561

High

443132

PAX6
Paired box protein Pax-6

1

20

High-throughput

0.561

High

443145

ELK3
ETS domain-containing protein Elk-3

1

20

High-throughput

0.561

High

443150

SOX9
Transcription factor SOX-9

1

20

High-throughput

0.561

High

443154

LHX2
LIM/homeobox protein Lhx2

1

14

High-throughput

0.561

High

443159

SOX10
Transcription factor SOX-10

1

20

High-throughput

0.561

High

443168

PAX2
Paired box protein Pax-2

1

20

High-throughput

0.561

High

443175

PAX8
Paired box protein Pax-8

1

20

High-throughput

0.561

High

443228

LHX4
LIM/homeobox protein Lhx4

1

14

High-throughput

0.561

High

443241

KLF16
Krueppel-like factor 16

1

14

High-throughput

0.561

High

443251

SOX17
Transcription factor SOX-17

1

20

High-throughput

0.561

High

443262

LHX3
LIM/homeobox protein Lhx3

1

14

High-throughput

0.561

High

443275

ETV7
Transcription factor ETV7

1

20

High-throughput

0.561

High

126421

FOXE1
Forkhead box protein E1

1

20

High-throughput

0.536

High

443124

CREB1
Cyclic AMP-responsive element-binding protein 1

1

4

High-throughput

0.536

High

443138

BMI1
Polycomb complex protein BMI-1

1

11

High-throughput

0.536

High

443147

KI67
Proliferation marker protein Ki-67

1

7

High-throughput

0.536

High

443157

FOXA1
Hepatocyte nuclear factor 3-alpha

1

20

High-throughput

0.536

High

443174

SUH
Recombining binding protein suppressor of hairless

1

2

High-throughput

0.536

High

443184

BIRC2
Baculoviral IAP repeat-containing protein 2

1

2

High-throughput

0.536

High

443187

FHL2
Four and a half LIM domains protein 2

1

5

High-throughput

0.536

High

443203

CTR9
RNA polymerase-associated protein CTR9 homolog

1

10

High-throughput

0.536

High

443260

ZKSC7
Zinc finger protein with KRAB and SCAN domains 7

1

0

High-throughput

0.518

High

268581

SF3B1
Splicing factor 3B subunit 1

1

3

High-throughput

0.515

High

443176

NCBP1
Nuclear cap-binding protein subunit 1

1

0

High-throughput

0.513

High

443117

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

6

High-throughput

0.501

High

443137

1433S
14-3-3 protein sigma

1

13

High-throughput

0.501

High

443144

SOX3
Transcription factor SOX-3

1

20

High-throughput

0.501

High

443169

TF65
Transcription factor p65

1

2

High-throughput

0.501

High

443181

FOXL1
Forkhead box protein L1

1

20

High-throughput

0.501

High

443193

TEAD2
Transcriptional enhancer factor TEF-4

1

4

High-throughput

0.501

High

443194

ELF2
ETS-related transcription factor Elf-2

1

20

High-throughput

0.501

High

443196

MK14
Mitogen-activated protein kinase 14

1

4

High-throughput

0.501

High

443197

TBR1
T-box brain protein 1

1

11

High-throughput

0.501

High

443215

GLIS1
Zinc finger protein GLIS1

1

4

High-throughput

0.501

High

443242

NSD3
Histone-lysine N-methyltransferase NSD3

1

20

High-throughput

0.501

High

443243

GLIS2
Zinc finger protein GLIS2

1

3

High-throughput

0.501

High

443264

DACH1
Dachshund homolog 1

1

1

High-throughput

0.501

High

443274

FBX7
F-box only protein 7

1

1

High-throughput

0.501

High

443259

RNF12
E3 ubiquitin-protein ligase RLIM

1

2

High-throughput

0.500

High

443148

MP2K3
Dual specificity mitogen-activated protein kinase kinase 3

1

0

High-throughput

0.480

High

443258

LATS2
Serine/threonine-protein kinase LATS2

1

0

High-throughput

0.480

High

443167

MSHR
Melanocyte-stimulating hormone receptor

1

0

High-throughput

0.479

High

122455

MEN1
Menin

1

5

High-throughput

0.479

High

146139

ARI1A
AT-rich interactive domain-containing protein 1A

1

20

High-throughput

0.479

High

152576

KMT2D
Histone-lysine N-methyltransferase 2D

1

20

High-throughput

0.479

High

164176

ZN609
Zinc finger protein 609

1

17

High-throughput

0.479

High

170219

TIF1A
Transcription intermediary factor 1-alpha

1

10

High-throughput

0.479

High

183053

KDM6A
Lysine-specific demethylase 6A

1

9

High-throughput

0.479

High

197649

CRX
Cone-rod homeobox protein

1

20

High-throughput

0.479

High

231194

ZEB2
Zinc finger E-box-binding homeobox 2

1

7

High-throughput

0.479

High

243819

BRD4
Bromodomain-containing protein 4

1

12

High-throughput

0.479

High

245553

TBL1X
F-box-like/WD repeat-containing protein TBL1X

1

16

High-throughput

0.479

High

261377

NCOR1
Nuclear receptor corepressor 1

1

20

High-throughput

0.479

High

265587

E2F6
Transcription factor E2F6

1

5

High-throughput

0.479

High

321689

WIZ
Protein Wiz

1

6

High-throughput

0.479

High

359585

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

5

High-throughput

0.479

High

431446

HS90A
Heat shock protein HSP 90-alpha

1

8

High-throughput

0.479

High

437818

HS90B
Heat shock protein HSP 90-beta

1

8

High-throughput

0.479

High

443116

ATX1L
Ataxin-1-like

1

9

High-throughput

0.479

High

443118

ANDR
Androgen receptor

1

20

High-throughput

0.479

High

443119

EGR2
E3 SUMO-protein ligase EGR2

1

6

High-throughput

0.479

High

443121

NR2C1
Nuclear receptor subfamily 2 group C member 1

1

15

High-throughput

0.479

High

443122

PO2F1
POU domain, class 2, transcription factor 1

1

12

High-throughput

0.479

High

443123

ZEP1
Zinc finger protein 40

1

6

High-throughput

0.479

High

443125

CEBPB
CCAAT/enhancer-binding protein beta

1

6

High-throughput

0.479

High

443126

EGR1
Early growth response protein 1

1

6

High-throughput

0.479

High

443127

RFX1
MHC class II regulatory factor RFX1

1

11

Small-scale

0.479

High

443133

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

3

High-throughput

0.479

High

443134

TEAD1
Transcriptional enhancer factor TEF-1

1

4

High-throughput

0.479

High

443136

TLX1
T-cell leukemia homeobox protein 1

1

20

High-throughput

0.479

High

443141

BRCA1
Breast cancer type 1 susceptibility protein

1

5

High-throughput

0.479

High

443142

COIL
Coilin

1

1

High-throughput

0.479

High

443143

CUX1
Homeobox protein cut-like 1

1

20

High-throughput

0.479

High

443146

NKX21
Homeobox protein Nkx-2.1

1

20

High-throughput

0.479

High

443151

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

15

High-throughput

0.479

High

443152

CEBPA
CCAAT/enhancer-binding protein alpha

1

8

High-throughput

0.479

High

443153

MNX1
Motor neuron and pancreas homeobox protein 1

1

11

High-throughput

0.479

High

443155

SMCA2
Probable global transcription activator SNF2L2

1

9

High-throughput

0.479

High

443156

ATX1
Ataxin-1

1

9

High-throughput

0.479

High

443158

PAX9
Paired box protein Pax-9

1

20

High-throughput

0.479

High

443160

GSC
Homeobox protein goosecoid

1

17

High-throughput

0.479

High

443162

H4
Histone H4

1

6

High-throughput

0.479

High

443163

H31
Histone H3.1

1

11

High-throughput

0.479

High

443165

H33
Histone H3.3

1

11

High-throughput

0.479

High

443170

TLE1
Transducin-like enhancer protein 1

1

20

High-throughput

0.479

High

443172

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

3

High-throughput

0.479

High

443173

HME1
Homeobox protein engrailed-1

1

7

High-throughput

0.479

High

443178

TP53B
TP53-binding protein 1

1

5

High-throughput

0.479

High

443180

FOXI1
Forkhead box protein I1

1

20

High-throughput

0.479

High

443182

RLF
Zinc finger protein Rlf

1

5

High-throughput

0.479

High

443183

GPS2
G protein pathway suppressor 2

1

1

High-throughput

0.479

High

443186

TFDP1
Transcription factor Dp-1

1

1

High-throughput

0.479

High

443188

MDC1
Mediator of DNA damage checkpoint protein 1

1

17

High-throughput

0.479

High

443191

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

1

High-throughput

0.479

High

443192

KIF14
Kinesin-like protein KIF14

1

2

High-throughput

0.479

High

443195

VPS72
Vacuolar protein sorting-associated protein 72 homolog

1

1

High-throughput

0.479

High

443198

ARI4B
AT-rich interactive domain-containing protein 4B

1

20

High-throughput

0.479

High

443199

BRM1L
Breast cancer metastasis-suppressor 1-like protein

1

1

High-throughput

0.479

High

443204

MDEAS
Mitotic deacetylase-associated SANT domain protein

1

10

High-throughput

0.479

High

443205

BCOR
BCL-6 corepressor

1

10

High-throughput

0.479

High

443207

PAXI1
PAX-interacting protein 1

1

11

High-throughput

0.479

High

443208

POGZ
Pogo transposable element with ZNF domain

1

1

High-throughput

0.479

High

443209

DTX2
Probable E3 ubiquitin-protein ligase DTX2

1

6

High-throughput

0.479

High

443210

FOXP4
Forkhead box protein P4

1

20

High-throughput

0.479

High

443211

ARI3B
AT-rich interactive domain-containing protein 3B

1

19

High-throughput

0.479

High

443212

MGAP
MAX gene-associated protein

1

11

High-throughput

0.479

High

443213

HOMEZ
Homeobox and leucine zipper protein Homez

1

20

High-throughput

0.479

High

443214

ZBT38
Zinc finger and BTB domain-containing protein 38

1

1

Small-scale

0.479

High

443216

ARI1B
AT-rich interactive domain-containing protein 1B

1

20

High-throughput

0.479

High

443217

NUP35
Nucleoporin NUP35

1

2

High-throughput

0.479

High

443218

KDM2B
Lysine-specific demethylase 2B

1

8

High-throughput

0.479

High

443220

MORC4
MORC family CW-type zinc finger protein 4

1

1

High-throughput

0.479

High

443221

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

1

High-throughput

0.479

High

443222

BCL7C
B-cell CLL/lymphoma 7 protein family member C

1

4

High-throughput

0.479

High

443224

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

443225

RREB1
Ras-responsive element-binding protein 1

1

2

High-throughput

0.479

High

443226

REQU
Zinc finger protein ubi-d4

1

20

High-throughput

0.479

High

443227

SMRD2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2

1

17

High-throughput

0.479

High

443229

LMBL2
Lethal(3)malignant brain tumor-like protein 2

1

6

High-throughput

0.479

High

443230

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

15

High-throughput

0.479

High

443231

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

1

10

High-throughput

0.479

High

443233

EHMT2
Histone-lysine N-methyltransferase EHMT2

1

8

High-throughput

0.479

High

443235

FEV
Protein FEV

1

20

High-throughput

0.479

High

443236

SCAFB
Protein SCAF11

1

8

High-throughput

0.479

High

443237

ARI3A
AT-rich interactive domain-containing protein 3A

1

19

High-throughput

0.479

High

443239

PCGF1
Polycomb group RING finger protein 1

1

11

High-throughput

0.479

High

443240

DDA1
DET1- and DDB1-associated protein 1

1

3

High-throughput

0.479

High

443244

TBL1R
F-box-like/WD repeat-containing protein TBL1XR1

1

15

High-throughput

0.479

High

443245

DPY30
Protein dpy-30 homolog

1

4

High-throughput

0.479

High

443247

SP130
Histone deacetylase complex subunit SAP130

1

14

High-throughput

0.479

High

443249

FOXP1
Forkhead box protein P1

1

20

High-throughput

0.479

High

443250

ZN644
Zinc finger protein 644

1

7

High-throughput

0.479

High

443252

EHMT1
Histone-lysine N-methyltransferase EHMT1

1

8

High-throughput

0.479

High

443254

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

8

Small-scale

0.479

High

443256

HM20A
High mobility group protein 20A

1

20

High-throughput

0.479

High

443257

TF7L2
Transcription factor 7-like 2

1

20

High-throughput

0.479

High

443261

RCOR3
REST corepressor 3

1

12

High-throughput

0.479

High

443263

TRPS1
Zinc finger transcription factor Trps1

1

11

High-throughput

0.479

High

443265

SIX4
Homeobox protein SIX4

1

4

High-throughput

0.479

High

443266

ZHX1
Zinc fingers and homeoboxes protein 1

1

18

High-throughput

0.479

High

443267

ZN608
Zinc finger protein 608

1

13

High-throughput

0.479

High

443268

PRR12
Proline-rich protein 12

1

19

High-throughput

0.479

High

443270

SATB2
DNA-binding protein SATB2

1

4

High-throughput

0.479

High

443271

ZN148
Zinc finger protein 148

1

9

High-throughput

0.479

High

443273

ZN281
Zinc finger protein 281

1

7

High-throughput

0.479

High

443276

NCOR2
Nuclear receptor corepressor 2

1

20

High-throughput

0.479

High

443277

NCOA3
Nuclear receptor coactivator 3

1

6

High-throughput

0.479

High

314599

PARN
Poly(A)-specific ribonuclease PARN

1

0

High-throughput

0.458

High

443202

TET2
Methylcytosine dioxygenase TET2

1

0

High-throughput

0.458

High

443135

EPHA2
Ephrin type-A receptor 2

1

3

High-throughput

0.457

High

443185

SNW1
SNW domain-containing protein 1

1

1

High-throughput

0.445

High

443200

Q5VW31
Nuclear factor I B

1

12

High-throughput

0.445

High

443223

ZCH14
Zinc finger CCHC domain-containing protein 14

1

13

High-throughput

0.439

High

443189

GSE1
Genetic suppressor element 1

1

3

High-throughput

0.437

High

443201

ZMYM4
Zinc finger MYM-type protein 4

1

2

High-throughput

0.437

High

443206

TRI67
Tripartite motif-containing protein 67

1

5

High-throughput

0.437

High

443246

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

1

2

High-throughput

0.437

High

443253

FBRS
Probable fibrosin-1

1

3

High-throughput

0.437

High

443255

FBSL
Fibrosin-1-like protein

1

3

High-throughput

0.437

High

443272

ITM2B
Integral membrane protein 2B

1

3

High-throughput

0.407

High

443232

TPD55
Tumor protein D55

1

0

High-throughput

0.282

High

443238

LLPH
Protein LLP homolog

1

0

High-throughput

0.282

High

443248

TKTL2
Transketolase-like protein 2

1

0

High-throughput

0.282

High

443269

CBLC
E3 ubiquitin-protein ligase CBL-C

1

0

High-throughput

0.261

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024