Protein: MLR
Myosin regulatory light chain 2 (MLC-2)

Gene: MLR, Mlc2
Organism: Drosophila melanogaster
Interactions: 121
UniProt ID: P18432

Gene Ontology (top 5):
GO:0003012 - muscle system process
GO:0005509 - calcium ion binding
GO:0005737 - cytoplasm
GO:0009791 - post-embryonic development
GO:0016460 - myosin II complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

432167

MYSA
Myosin heavy chain, muscle

2

19

High-throughput

0.737

High

446263

MLC1
Myosin light chain alkali

2

20

High-throughput

0.737

High

614557

TNNC1
Troponin C, isoform 1

2

20

High-throughput

0.737

High

614574

Q7K569
Glycerol-3-phosphate dehydrogenase

2

20

High-throughput

0.737

High

614576

Q7K860
FI07231p

2

20

High-throughput

0.737

High

614558

TNNC2
Troponin C, isoform 2

1

20

High-throughput

0.575

High

614559

TNNC3
Troponin C, isoform 3

1

20

High-throughput

0.575

High

614617

Q9VMT2
GEO07854p1

1

20

High-throughput

0.575

High

387028

ACT4
Actin, larval muscle

2

6

High-throughput

0.571

High

578026

ENO
Enolase

2

1

High-throughput

0.571

High

612356

ACTN
Alpha-actinin, sarcomeric

2

6

High-throughput

0.571

High

614553

MYSP2
Paramyosin, short form

2

20

High-throughput

0.571

High

614562

ACT6
Actin, indirect flight muscle

2

6

High-throughput

0.571

High

614606

Q9VEB1
Malate dehydrogenase, mitochondrial

2

1

High-throughput

0.571

High

567540

GPDA
Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic

2

0

High-throughput

0.547

High

614552

TNNT
Troponin T, skeletal muscle

2

0

High-throughput

0.547

High

614555

TNNI
Troponin I

2

0

High-throughput

0.547

High

614556

GSTS1
Glutathione S-transferase S1

2

0

High-throughput

0.547

High

614560

KARG
Arginine kinase 1

2

0

High-throughput

0.547

High

614561

DHE3
Glutamate dehydrogenase, mitochondrial

2

0

High-throughput

0.547

High

614584

Q8MSI2
GH15296p

2

0

High-throughput

0.547

High

358461

ADH
Alcohol dehydrogenase

2

1

High-throughput

0.521

High

482726

TPM2
Tropomyosin-2

2

1

High-throughput

0.521

High

614615

Q9VM18
Trehalose 6-phosphate phosphatase

2

1

High-throughput

0.521

High

614577

Q7KQP6
Bent, isoform C

1

12

High-throughput

0.514

High

614593

Q961D4
Rho-associated protein kinase

1

14

High-throughput

0.492

High

614608

PAK
Serine/threonine-protein kinase Pak

1

6

High-throughput

0.492

High

467154

CSK2B
Casein kinase II subunit beta

1

0

High-throughput

0.486

High

119510

M9NHC5
Uncharacterized protein, isoform C

1

6

High-throughput

0.479

High

614600

FRIL
Ferritin light chain

1

1

High-throughput

0.479

High

614613

Q9VL02
GH08677p

1

6

High-throughput

0.464

High

614626

ULA1
Nedd8-activating enzyme E1 regulatory subunit

1

1

High-throughput

0.464

High

614639

SCN60
Sodium channel protein 60E

1

4

High-throughput

0.464

High

614611

Q9VIX6
GH19142p

1

1

High-throughput

0.451

High

56342

ZASP
PDZ and LIM domain protein Zasp

1

7

High-throughput

0.445

High

534345

ACT5
Actin-87E

1

6

High-throughput

0.445

High

571701

MP20
Muscle-specific protein 20

1

18

High-throughput

0.445

High

614579

Q8I0D4
RE20510p

1

3

High-throughput

0.445

High

614624

Q9VSA9
CG7409

1

6

High-throughput

0.445

High

614632

Q9VWG1
LD37169p

1

6

High-throughput

0.445

High

120552

M9PDL4
Multiple wing hairs, isoform B

1

4

High-throughput

0.439

High

614564

Q0E8P1
Uncharacterized protein, isoform B

1

1

High-throughput

0.439

High

614619

Q9VQ96
RH13166p

1

1

High-throughput

0.439

High

614583

Q8IQQ0
2-oxoglutarate dehydrogenase, mitochondrial

1

4

High-throughput

0.437

High

614591

VDAC
Voltage-dependent anion-selective channel

1

1

High-throughput

0.437

High

145949

UGDH
UDP-glucose 6-dehydrogenase

1

0

High-throughput

0.426

High

444115

TBA2
Tubulin alpha-2 chain

1

0

High-throughput

0.426

High

614575

SCARF
Inactive serine protease scarface

1

0

High-throughput

0.426

High

614580

MSRB
Methionine-R-sulfoxide reductase B1

1

0

High-throughput

0.426

High

614582

Q8IQB4
Z band alternatively spliced PDZ-motif protein 66, isoform E

1

0

High-throughput

0.426

High

614629

SMN
Survival motor neuron protein

1

0

High-throughput

0.426

High

614622

Q9VRE6
GH12419p1

1

1

High-throughput

0.417

High

614636

Q9W053
Zormin, isoform F

1

10

High-throughput

0.417

High

614638

Q9W0J2
Multiple wing hairs, isoform A

1

4

High-throughput

0.417

High

68041

A8DRW0
Cuticular protein 49Aa

1

3

High-throughput

0.407

High

87083

Y5076
Uncharacterized protein CG45076

1

20

High-throughput

0.407

High

87146

FAU
Protein anoxia up-regulated

1

1

High-throughput

0.407

High

360511

COX2
Cytochrome c oxidase subunit 2

1

1

High-throughput

0.407

High

444170

VIT3
Vitellogenin-3

1

1

High-throughput

0.407

High

447912

TPM1
Tropomyosin-1, isoforms 9A/A/B

1

2

High-throughput

0.407

High

614572

Q7JUS9
Phosphate carrier protein, mitochondrial

1

4

High-throughput

0.407

High

614573

Q7K2P1
Cuticular protein 50Cb

1

1

High-throughput

0.407

High

614585

Q8MT78
LD24677p

1

1

High-throughput

0.407

High

614586

Q8MYR8
RH74685p

1

7

High-throughput

0.407

High

614592

Q95RB2
Cuticular protein 49Ae

1

3

High-throughput

0.407

High

614594

Q9I7J0
GH21596p

1

16

High-throughput

0.407

High

614595

Q9I7Q5
Cuticular protein 65Au, isoform A

1

2

High-throughput

0.407

High

614597

CP4G1
Cytochrome P450 4g1

1

2

High-throughput

0.407

High

614599

CP4C3
Cytochrome P450 4c3

1

2

High-throughput

0.407

High

614605

WDR20
WD repeat-containing protein 20 homolog

1

1

High-throughput

0.407

High

614612

Q9VKW1
LD41958p

1

1

High-throughput

0.407

High

614630

Q9VVC5
2-oxoglutarate dehydrogenase, mitochondrial

1

4

High-throughput

0.407

High

614635

Q9VZI4
Uncharacterized protein, isoform A

1

3

High-throughput

0.407

High

614637

Q9W077
Cuticular protein 62Bc, isoform A

1

1

High-throughput

0.407

High

614644

Q9W4H6
Pyruvate dehydrogenase E1 component subunit alpha

1

4

High-throughput

0.407

High

305046

O77134

2

0

High-throughput

0.310

High

614607

Q9VFL4
AT18408p

2

0

High-throughput

0.310

High

57247

ICLN
Methylosome subunit pICln

2

0

High-throughput

0.298

High

459982

ALF
Fructose-bisphosphate aldolase

2

0

High-throughput

0.298

High

614554

FTN
Flightin

2

0

High-throughput

0.298

High

614563

CYC2
Cytochrome c-2

2

0

High-throughput

0.298

High

614567

ATP5J
ATP synthase-coupling factor 6, mitochondrial

2

0

High-throughput

0.298

High

614568

ATPO
ATP synthase subunit O, mitochondrial

2

0

High-throughput

0.298

High

614570

Q6IHY5
Cytochrome c oxidase subunit 7A-like 2, isoform A

2

0

High-throughput

0.298

High

614578

Q8I062
GH23305p

2

0

High-throughput

0.298

High

614590

AT5F1
ATP synthase subunit b, mitochondrial

2

0

High-throughput

0.298

High

614609

Q9VIE8
Aconitate hydratase, mitochondrial

2

0

High-throughput

0.298

High

614610

Q9VIQ8
Cytochrome c oxidase subunit 4

2

0

High-throughput

0.298

High

614618

Q9VP84
IP06402p

2

0

High-throughput

0.298

High

614623

Q9VRL0
Cytochrome c1, heme protein, mitochondrial

2

0

High-throughput

0.298

High

614627

NPLP2
Neuropeptide-like 2

2

0

High-throughput

0.298

High

614640

ATPK
Putative ATP synthase subunit f, mitochondrial

2

0

High-throughput

0.298

High

614642

CISY
Probable citrate synthase, mitochondrial

2

0

High-throughput

0.298

High

450805

CH38
Chorion protein S38

1

0

High-throughput

0.265

Low

614571

Q6NQZ7
LD40663p

1

0

High-throughput

0.265

Low

614596

Q9NCC3
Sorting nexin

1

0

High-throughput

0.265

Low

614620

Q9VQL2
LD44813p

1

0

High-throughput

0.265

Low

614645

Q9W4M0
GEO11596p1

1

0

High-throughput

0.265

Low

614581

Q8IPY8
IP07509p

1

0

High-throughput

0.257

Low

614569

CUA1
Adult cuticle protein 1

1

0

High-throughput

0.249

Low

614587

OB56D
General odorant-binding protein 56d

1

0

High-throughput

0.249

Low

614604

Q9VBA0
GH09623p

1

0

High-throughput

0.249

Low

614621

Q9VQR2
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10

1

0

High-throughput

0.249

Low

614628

Q9VV21
GEO07736p1

1

0

High-throughput

0.249

Low

614633

NDUS4
NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial

1

0

High-throughput

0.249

Low

458076

G3P2
Glyceraldehyde-3-phosphate dehydrogenase 2

1

0

High-throughput

0.232

Low

614565

ATP5H
ATP synthase subunit d, mitochondrial

1

0

High-throughput

0.232

Low

614566

RUXF
Small nuclear ribonucleoprotein F

1

0

High-throughput

0.232

Low

614588

Q8SZM2
RH04334p

1

0

High-throughput

0.232

Low

614589

COX5A
Cytochrome c oxidase subunit 5A, mitochondrial

1

0

High-throughput

0.232

Low

614598

Q9V9U0
RE35358p

1

0

High-throughput

0.232

Low

614601

Q9VA92
RH14937p

1

0

High-throughput

0.232

Low

614602

Q9VAC1
GM14349p

1

0

High-throughput

0.232

Low

614603

Q9VB86
LP07342p

1

0

High-throughput

0.232

Low

614614

Q9VLX9
Uncharacterized protein, isoform B

1

0

High-throughput

0.232

Low

614616

Q9VMB9
Cytochrome c oxidase subunit 5B, isoform A

1

0

High-throughput

0.232

Low

614625

Q9VSY0
Cuticular protein 67B

1

0

High-throughput

0.232

Low

614631

Q9VVV1
RE59221p

1

0

High-throughput

0.232

Low

614634

SUN
Protein stunted

1

0

High-throughput

0.232

Low

614641

Q9W2X6
ATP synthase F(1) complex subunit delta, mitochondrial

1

0

High-throughput

0.232

Low

614643

THEM6
Protein THEM6

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025