Protein: PPIL4
Peptidyl-prolyl cis-trans isomerase-like 4 (PPIase) (EC 5.2.1.8) (Cyclophilin-like protein PPIL4) (Rotamase PPIL4)

Gene: PPIL4
Organism: Homo sapiens
Interactions: 157
UniProt ID: Q8WUA2

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0003755 - peptidyl-prolyl cis-trans isomerase activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

586881

CSK22
Casein kinase II subunit alpha'

1

3

High-throughput

0.691

High

1259856

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

4

3

Small-scale

0.691

High

198939

RFOX2
RNA binding protein fox-1 homolog 2

1

5

High-throughput

0.621

High

149097

CTRO
Citron Rho-interacting kinase

1

4

High-throughput

0.618

High

163050

XPO1
Exportin-1

1

1

High-throughput

0.618

High

325826

LATS1
Serine/threonine-protein kinase LATS1

1

2

High-throughput

0.618

High

374592

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

5

High-throughput

0.618

High

613530

SFPQ
Splicing factor, proline- and glutamine-rich

1

2

High-throughput

0.618

High

726950

FUS
RNA-binding protein FUS

1

6

High-throughput

0.618

High

822331

KC1D
Casein kinase I isoform delta

1

1

High-throughput

0.618

High

830436

KC1E
Casein kinase I isoform epsilon

1

1

High-throughput

0.618

High

833488

RBM25
RNA-binding protein 25

1

4

High-throughput

0.618

High

841821

CDK9
Cyclin-dependent kinase 9

1

3

High-throughput

0.618

High

916283

RL23A
Large ribosomal subunit protein uL23

1

1

High-throughput

0.618

High

983881

KPCZ
Protein kinase C zeta type

1

2

High-throughput

0.618

High

1014173

CPSF1
Cleavage and polyadenylation specificity factor subunit 1

1

1

High-throughput

0.618

High

1037852

PRP4K
Serine/threonine-protein kinase PRP4 homolog

1

4

High-throughput

0.618

High

1054459

RBM39
RNA-binding protein 39

1

5

High-throughput

0.618

High

1069750

NONO
Non-POU domain-containing octamer-binding protein

1

3

High-throughput

0.618

High

1073605

SF3B4
Splicing factor 3B subunit 4

1

2

High-throughput

0.618

High

1084542

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

5

High-throughput

0.618

High

1235752

CPSF7
Cleavage and polyadenylation specificity factor subunit 7

1

4

High-throughput

0.618

High

1242558

RB15B
Putative RNA-binding protein 15B

1

1

High-throughput

0.618

High

1259852

PSPC1
Paraspeckle component 1

1

3

High-throughput

0.618

High

1259853

REQU
Zinc finger protein ubi-d4

1

3

High-throughput

0.618

High

1259854

KAT6A
Histone acetyltransferase KAT6A

1

2

High-throughput

0.618

High

1259855

CELF1
CUGBP Elav-like family member 1

1

1

High-throughput

0.618

High

1259860

PP1RA
Serine/threonine-protein phosphatase 1 regulatory subunit 10

1

2

High-throughput

0.618

High

1259881

TBK1
Serine/threonine-protein kinase TBK1

1

3

High-throughput

0.618

High

1220240

DHX40
Probable ATP-dependent RNA helicase DHX40

2

3

High-throughput

0.611

High

1259868

NSRP1
Nuclear speckle splicing regulatory protein 1

2

1

High-throughput

0.611

High

1077284

DLG2
Disks large homolog 2

2

1

High-throughput

0.606

High

1157345

JMJD6
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6

2

0

High-throughput

0.602

High

214998

CPSF5
Cleavage and polyadenylation specificity factor subunit 5

1

0

High-throughput

0.586

High

906041

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

0

High-throughput

0.586

High

1077426

ELAV1
ELAV-like protein 1

1

0

High-throughput

0.586

High

1252957

R3GEF
Guanine nucleotide exchange factor for Rab-3A

2

0

High-throughput

0.585

High

1259886

LC7L2
Putative RNA-binding protein Luc7-like 2

2

0

High-throughput

0.585

High

1259887

AMMR1
Nuclear protein AMMECR1

2

0

High-throughput

0.585

High

1259888

ORC6
Origin recognition complex subunit 6

2

0

High-throughput

0.585

High

228166

PRKN
E3 ubiquitin-protein ligase parkin

2

4

High-throughput

0.584

High

244691

BRD4
Bromodomain-containing protein 4

2

4

High-throughput

0.584

High

322918

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

2

3

High-throughput

0.584

High

347423

MYC
Myc proto-oncogene protein

2

8

High-throughput

0.584

High

360203

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

2

6

High-throughput

0.584

High

917645

H4
Histone H4

2

1

High-throughput

0.584

High

641493

PAX6
Paired box protein Pax-6

2

0

High-throughput

0.580

High

1130367

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

7

High-throughput

0.575

High

1256716

ARH40
Rho guanine nucleotide exchange factor 40

2

2

High-throughput

0.571

High

282977

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

2

5

High-throughput

0.558

High

849793

SUOX
Sulfite oxidase, mitochondrial

1

0

High-throughput

0.557

High

155056

NDC80
Kinetochore protein NDC80 homolog

1

1

High-throughput

0.536

High

236808

CCNT1
Cyclin-T1

1

3

High-throughput

0.536

High

303376

HEXI1
Protein HEXIM1

1

2

High-throughput

0.536

High

617342

SP100
Nuclear autoantigen Sp-100

1

8

High-throughput

0.536

High

1259858

TMA16
Translation machinery-associated protein 16

1

1

High-throughput

0.536

High

132184

PESC
Pescadillo homolog

1

0

High-throughput

0.513

High

207077

XRCC3
DNA repair protein XRCC3

1

0

High-throughput

0.513

High

1259850

SNR27
U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein

1

0

High-throughput

0.513

High

1259882

NAGK
N-acetyl-D-glucosamine kinase

1

0

High-throughput

0.513

High

1219710

CHERP
Calcium homeostasis endoplasmic reticulum protein

1

4

High-throughput

0.508

High

1062597

EMC2
ER membrane protein complex subunit 2

1

2

High-throughput

0.489

High

1170337

CAN12
Calpain-12

1

1

High-throughput

0.489

High

1233901

EMC5
ER membrane protein complex subunit 5

1

1

High-throughput

0.489

High

1259862

SMAD5
Mothers against decapentaplegic homolog 5

1

0

High-throughput

0.486

High

123294

CBX4
E3 SUMO-protein ligase CBX4

1

3

High-throughput

0.479

High

179742

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

4

High-throughput

0.479

High

199791

SNUT1
U4/U6.U5 tri-snRNP-associated protein 1

1

1

High-throughput

0.479

High

237408

CCNT2
Cyclin-T2

1

4

High-throughput

0.479

High

263754

PR40A
Pre-mRNA-processing factor 40 homolog A

1

7

High-throughput

0.479

High

295050

RECQ4
ATP-dependent DNA helicase Q4

1

3

High-throughput

0.479

High

297531

TOX4
TOX high mobility group box family member 4

1

7

High-throughput

0.479

High

304260

UBR5
E3 ubiquitin-protein ligase UBR5

1

4

High-throughput

0.479

High

418493

NPM
Nucleophosmin

1

1

High-throughput

0.479

High

445480

RSSA
Small ribosomal subunit protein uS2

1

4

High-throughput

0.479

High

508625

TOP1
DNA topoisomerase 1

1

4

High-throughput

0.479

High

523894

XRCC6
X-ray repair cross-complementing protein 6

1

1

High-throughput

0.479

High

553273

RFA2
Replication protein A 32 kDa subunit

1

5

High-throughput

0.479

High

595328

LMNB1
Lamin-B1

1

6

High-throughput

0.479

High

640559

DDX6
Probable ATP-dependent RNA helicase DDX6

1

3

High-throughput

0.479

High

651777

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

4

High-throughput

0.479

High

721000

RFA3
Replication protein A 14 kDa subunit

1

4

High-throughput

0.479

High

727899

SOX6
Transcription factor SOX-6

1

4

High-throughput

0.479

High

779796

CCNF
Cyclin-F

1

6

High-throughput

0.479

High

848090

MECP2
Methyl-CpG-binding protein 2

1

1

High-throughput

0.479

High

908872

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

4

High-throughput

0.479

High

918545

H2B1C
Histone H2B type 1-C/E/F/G/I

1

1

High-throughput

0.479

High

924091

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein

1

2

High-throughput

0.479

High

924363

RL40
Ubiquitin-ribosomal protein eL40 fusion protein

1

2

High-throughput

0.479

High

929337

IF5A1
Eukaryotic translation initiation factor 5A-1

1

1

High-throughput

0.479

High

932279

ACTC
Actin, alpha cardiac muscle 1

1

1

High-throughput

0.479

High

990573

CKAP4
Cytoskeleton-associated protein 4

1

7

High-throughput

0.479

High

998910

EP300
Histone acetyltransferase p300

1

2

High-throughput

0.479

High

1042136

CUL3
Cullin-3

1

1

High-throughput

0.479

High

1052267

SRC8
Src substrate cortactin

1

3

High-throughput

0.479

High

1054072

GRB7
Growth factor receptor-bound protein 7

1

3

Small-scale

0.479

High

1055435

DHX8
ATP-dependent RNA helicase DHX8

1

3

High-throughput

0.479

High

1081336

E2F4
Transcription factor E2F4

1

5

High-throughput

0.479

High

1133691

RHG21
Rho GTPase-activating protein 21

1

3

High-throughput

0.479

High

1138655

ARHGG
Rho guanine nucleotide exchange factor 16

1

7

High-throughput

0.479

High

1164850

FIP1
Pre-mRNA 3'-end-processing factor FIP1

1

1

High-throughput

0.479

High

1166699

WDR82
WD repeat-containing protein 82

1

10

High-throughput

0.479

High

1174604

H32
Histone H3.2

1

4

High-throughput

0.479

High

1184227

MEPCE
7SK snRNA methylphosphate capping enzyme

1

3

High-throughput

0.479

High

1221594

SMC5
Structural maintenance of chromosomes protein 5

1

1

High-throughput

0.479

High

1222481

SLX4
Structure-specific endonuclease subunit SLX4

1

3

High-throughput

0.479

High

1259851

ATX2L
Ataxin-2-like protein

1

3

High-throughput

0.479

High

1259857

FBXW7
F-box/WD repeat-containing protein 7

1

1

High-throughput

0.479

High

1259864

TACO1
Translational activator of cytochrome c oxidase 1

1

1

High-throughput

0.479

High

1259866

DDX23
Probable ATP-dependent RNA helicase DDX23

1

2

High-throughput

0.479

High

1259870

MET17
Ribosome assembly protein METTL17, mitochondrial

1

1

High-throughput

0.479

High

1259871

ANLN
Anillin

1

2

High-throughput

0.479

High

1259872

ARHG4
Rho guanine nucleotide exchange factor 4

1

4

High-throughput

0.479

High

1259873

DCA13
DDB1- and CUL4-associated factor 13

1

3

High-throughput

0.479

High

1259874

DDX56
Probable ATP-dependent RNA helicase DDX56

1

4

High-throughput

0.479

High

1259876

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

1

High-throughput

0.479

High

1259877

ITSN2
Intersectin-2

1

10

High-throughput

0.479

High

1259878

GMIP
GEM-interacting protein

1

4

High-throughput

0.479

High

1259879

NXF1
Nuclear RNA export factor 1

1

1

High-throughput

0.479

High

1259880

ZRAN1
Ubiquitin thioesterase ZRANB1

1

8

High-throughput

0.479

High

1259885

RCL1
RNA 3'-terminal phosphate cyclase-like protein

1

1

High-throughput

0.479

High

470473

H2A1
Histone H2A type 1

1

0

High-throughput

0.458

High

518728

IMDH2
Inosine-5'-monophosphate dehydrogenase 2

1

0

High-throughput

0.458

High

632827

TYY1
Transcriptional repressor protein YY1

1

0

High-throughput

0.458

High

750374

COIL
Coilin

1

0

High-throughput

0.458

High

759752

RS19
Small ribosomal subunit protein eS19

1

0

High-throughput

0.458

High

781642

ETV6
Transcription factor ETV6

1

0

High-throughput

0.458

High

817714

PI42A
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha

1

0

High-throughput

0.458

High

875692

MFAP1
Microfibrillar-associated protein 1

1

0

High-throughput

0.458

High

1158788

TAF2
Transcription initiation factor TFIID subunit 2

1

0

High-throughput

0.458

High

1189878

NUFP2
FMR1-interacting protein NUFIP2

1

0

High-throughput

0.458

High

1204678

DDX42
ATP-dependent RNA helicase DDX42

1

0

High-throughput

0.458

High

1239254

PR38A
Pre-mRNA-splicing factor 38A

1

0

High-throughput

0.458

High

1259861

POP1
Ribonucleases P/MRP protein subunit POP1

1

0

High-throughput

0.458

High

1259863

ANM1
Protein arginine N-methyltransferase 1

1

0

High-throughput

0.458

High

1259865

MMTA2
Multiple myeloma tumor-associated protein 2

1

0

High-throughput

0.458

High

1259875

MTMR4
Myotubularin-related protein 4

1

0

High-throughput

0.458

High

1259884

CC14A
Dual specificity protein phosphatase CDC14A

1

0

High-throughput

0.458

High

1259889

SPIN1
Spindlin-1

1

0

High-throughput

0.458

High

1120407

NCBP3
Nuclear cap-binding protein subunit 3

1

1

High-throughput

0.445

High

385227

NTRK1
High affinity nerve growth factor receptor

1

4

High-throughput

0.437

High

1044403

PTC1
Protein patched homolog 1

1

1

Small-scale

0.437

High

1170972

TRI67
Tripartite motif-containing protein 67

1

10

High-throughput

0.437

High

1219665

RHG12
Rho GTPase-activating protein 12

1

4

High-throughput

0.437

High

1259859

DDRGK
DDRGK domain-containing protein 1

1

1

High-throughput

0.437

High

1259869

PKHA4
Pleckstrin homology domain-containing family A member 4

1

3

High-throughput

0.437

High

1259883

HECD1
E3 ubiquitin-protein ligase HECTD1

1

3

High-throughput

0.437

High

1245616

ARK74
Aflatoxin B1 aldehyde reductase member 4

1

0

High-throughput

0.426

High

949034

HTRA4
Serine protease HTRA4

1

0

High-throughput

0.279

Low

1238283

F133A
Protein FAM133A

1

0

High-throughput

0.279

Low

1238847

TTC29
Tetratricopeptide repeat protein 29

1

0

High-throughput

0.279

Low

335152

DHE3
Glutamate dehydrogenase 1, mitochondrial

1

0

High-throughput

0.249

Low

674702

AMRP
Alpha-2-macroglobulin receptor-associated protein

1

0

High-throughput

0.249

Low

1126286

FA76B
Protein FAM76B

1

0

High-throughput

0.249

Low

1239303

KDF1
Keratinocyte differentiation factor 1

1

0

High-throughput

0.249

Low

1259867

ACE2
Angiotensin-converting enzyme 2

1

0

High-throughput

0.249

Low

1186108

T2R42
Taste receptor type 2 member 42

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024