Protein: CDKL5
Cyclin-dependent kinase-like 5 (EC 2.7.11.22)

Gene: CDKL5
Organism: Mus musculus
Interactions: 86
UniProt ID: Q3UTQ8

Gene Ontology (top 5):
GO:0001764 - neuron migration
GO:0004672 - protein kinase activity
GO:0004693 - cyclin-dependent protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

471545

LRC4B
Leucine-rich repeat-containing protein 4B

1

2

High-throughput

0.618

High

513676

HS90B
Heat shock protein HSP 90-beta

1

20

High-throughput

0.618

High

814028

MP2K4
Dual specificity mitogen-activated protein kinase kinase 4

1

20

High-throughput

0.618

High

949280

TNIK
Traf2 and NCK-interacting protein kinase

1

15

High-throughput

0.618

High

1113257

CDKL5
Cyclin-dependent kinase-like 5

1

17

High-throughput

0.618

High

1113277

CNKR2
Connector enhancer of kinase suppressor of ras 2

1

11

High-throughput

0.618

High

1113279

SHAN2
SH3 and multiple ankyrin repeat domains protein 2

1

7

High-throughput

0.618

High

1113283

ANS1B
Ankyrin repeat and sterile alpha motif domain-containing protein 1B

1

3

High-throughput

0.618

High

1113304

MINK1
Misshapen-like kinase 1

1

14

High-throughput

0.618

High

1113305

KC1E
Casein kinase I isoform epsilon

1

9

High-throughput

0.618

High

1113306

AFAD
Afadin

1

10

High-throughput

0.618

High

1113263

DLG4
Disks large homolog 4

2

6

High-throughput

0.584

High

956341

G3BP2
Ras GTPase-activating protein-binding protein 2

1

4

High-throughput

0.553

High

1113242

ARHG9
Rho guanine nucleotide exchange factor 9

1

5

Small-scale

0.553

High

57137

LZTS3
Leucine zipper putative tumor suppressor 3

1

20

High-throughput

0.479

High

57622

RBGP1
Rab GTPase-activating protein 1

1

1

High-throughput

0.479

High

69914

DLGP4
Disks large-associated protein 4

1

7

High-throughput

0.479

High

99975

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

6

High-throughput

0.479

High

193585

CTND2
Catenin delta-2

1

11

High-throughput

0.479

High

250863

MOT2
Monocarboxylate transporter 2

1

2

High-throughput

0.479

High

570755

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

6

High-throughput

0.479

High

620950

GRIA2
Glutamate receptor 2

1

6

High-throughput

0.479

High

723578

NMDZ1
Glutamate receptor ionotropic, NMDA 1

1

8

High-throughput

0.479

High

761853

ZO1
Tight junction protein ZO-1

1

9

High-throughput

0.479

High

886879

RHG39
Rho GTPase-activating protein 39

1

3

High-throughput

0.479

High

906256

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

15

High-throughput

0.479

High

936178

DLG3
Disks large homolog 3

1

6

High-throughput

0.479

High

963723

NMDE2
Glutamate receptor ionotropic, NMDA 2B

1

8

High-throughput

0.479

High

970130

CTNB1
Catenin beta-1

1

10

High-throughput

0.479

High

977383

KCNB1
Potassium voltage-gated channel subfamily B member 1

1

3

High-throughput

0.479

High

1113258

IQEC2
IQ motif and SEC7 domain-containing protein 2

1

3

High-throughput

0.479

High

1113262

CP131
Centrosomal protein of 131 kDa

1

20

High-throughput

0.479

High

1113264

SRBS1
Sorbin and SH3 domain-containing protein 1

1

5

High-throughput

0.479

High

1113268

DLGP3
Disks large-associated protein 3

1

7

High-throughput

0.479

High

1113270

NEB2
Neurabin-2

1

20

High-throughput

0.479

High

1113273

LRRC7
Leucine-rich repeat-containing protein 7

1

1

High-throughput

0.479

High

1113274

ERBIN
Erbin

1

3

High-throughput

0.479

High

1113275

AGRL3
Adhesion G protein-coupled receptor L3

1

1

High-throughput

0.479

High

1113276

UBP2L
Ubiquitin-associated protein 2-like

1

6

High-throughput

0.479

High

1113278

MYOME
Myomegalin

1

19

High-throughput

0.479

High

1113284

DLGP2
Disks large-associated protein 2

1

7

High-throughput

0.479

High

1113285

BAIP2
BAR/IMD domain-containing adapter protein 2

1

1

High-throughput

0.479

High

1113287

Q8BPK8
Agenet-like domain-containing protein

1

7

High-throughput

0.479

High

1113290

STAU2
Double-stranded RNA-binding protein Staufen homolog 2

1

5

High-throughput

0.479

High

1113291

IQEC1
IQ motif and SEC7 domain-containing protein 1

1

3

High-throughput

0.479

High

1113296

UBAP2
Ubiquitin-associated protein 2

1

5

High-throughput

0.479

High

1113297

DLG2
Disks large homolog 2

1

7

High-throughput

0.479

High

1113301

DLGP1
Disks large-associated protein 1

1

7

High-throughput

0.479

High

1113302

RBP2
E3 SUMO-protein ligase RanBP2

1

6

High-throughput

0.479

High

1113303

HIP1R
Huntingtin-interacting protein 1-related protein

1

20

High-throughput

0.479

High

1113307

PCM1
Pericentriolar material 1 protein

1

3

High-throughput

0.479

High

812773

RP3A
Rabphilin-3A

1

0

High-throughput

0.458

High

881950

SMO
Protein smoothened

1

0

Small-scale

0.458

High

956915

XRN1
5'-3' exoribonuclease 1

1

0

High-throughput

0.458

High

1113259

NUFP2
FMR1-interacting protein NUFIP2

1

0

High-throughput

0.458

High

1113261

ASTN1
Astrotactin-1

1

0

High-throughput

0.458

High

1113271

PLPR4
Phospholipid phosphatase-related protein type 4

1

0

High-throughput

0.458

High

1113288

GEPH
Gephyrin [Includes: Molybdopterin adenylyltransferase

1

0

Small-scale

0.458

High

1113292

CACB4
Voltage-dependent L-type calcium channel subunit beta-4

1

0

High-throughput

0.458

High

1113299

RTRAF
RNA transcription, translation and transport factor protein

1

0

High-throughput

0.458

High

61655

KCNB2
Potassium voltage-gated channel subfamily B member 2

1

3

High-throughput

0.437

High

498403

GSTM1
Glutathione S-transferase Mu 1

1

2

High-throughput

0.437

High

640293

GBRA2
Gamma-aminobutyric acid receptor subunit alpha-2

1

1

High-throughput

0.437

High

886901

YTHD1
YTH domain-containing family protein 1

1

2

High-throughput

0.437

High

918813

GBRA1
Gamma-aminobutyric acid receptor subunit alpha-1

1

1

High-throughput

0.437

High

1102416

PSD3
PH and SEC7 domain-containing protein 3

1

3

High-throughput

0.437

High

1111984

PRC2C
Protein PRRC2C

1

5

High-throughput

0.437

High

1112543

DAB2P
Disabled homolog 2-interacting protein

1

6

High-throughput

0.437

High

1113260

SC6A4
Sodium-dependent serotonin transporter

1

1

High-throughput

0.437

High

1113266

PPR29
Protein phosphatase 1 regulatory subunit 29

1

3

High-throughput

0.437

High

1113272

ATX2L
Ataxin-2-like protein

1

3

High-throughput

0.437

High

1113280

AGRB3
Adhesion G protein-coupled receptor B3

1

1

High-throughput

0.437

High

1113281

SLIK5
SLIT and NTRK-like protein 5

1

2

High-throughput

0.437

High

1113289

ELFN1
Protein ELFN1

1

3

High-throughput

0.437

High

1113293

EIF3C
Eukaryotic translation initiation factor 3 subunit C

1

3

High-throughput

0.437

High

1113294

SH3K1
SH3 domain-containing kinase-binding protein 1

1

2

High-throughput

0.437

High

1113295

SGIP1
SH3-containing GRB2-like protein 3-interacting protein 1

1

4

High-throughput

0.437

High

1113300

RL14
Large ribosomal subunit protein eL14

1

2

High-throughput

0.437

High

57169

AJM1
Apical junction component 1 homolog

1

0

High-throughput

0.249

Low

1113265

SANBR
SANT and BTB domain regulator of class switch recombination

1

0

High-throughput

0.249

Low

1113267

FBX41
F-box only protein 41

1

0

High-throughput

0.249

Low

1113269

RICTR
Rapamycin-insensitive companion of mTOR

1

0

High-throughput

0.249

Low

1113282

PCKGM
Phosphoenolpyruvate carboxykinase [GTP], mitochondrial

1

0

High-throughput

0.249

Low

1113286

Q8BNP7
Adenomatous polyposis coli N-terminal dimerisation domain-containing protein

1

0

High-throughput

0.249

Low

1113298

QCR8
Cytochrome b-c1 complex subunit 8

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024