Protein: ASAP1
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 (130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein) (ADP-ribosylation factor-directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (DEF-1) (Differentiation-enhancing factor 1) (PIP2-dependent ARF1 GAP)

Gene: ASAP1
Organism: Homo sapiens
Interactions: 64
UniProt ID: Q9ULH1

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0001786 - phosphatidylserine binding
GO:0002102 - podosome
GO:0005096 - GTPase activator activity
GO:0005546 - phosphatidylinositol-4,5-bisphosphate binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

924943

GRB2
Growth factor receptor-bound protein 2

9

20

High-throughput

0.974

High

1285221

SH3K1
SH3 domain-containing kinase-binding protein 1

7

20

Small-scale

0.962

High

802771

CRK
Adapter molecule crk

6

20

Small-scale

0.937

High

1052345

SRC8
Src substrate cortactin

5

15

Small-scale

0.936

High

983689

FAK1
Focal adhesion kinase 1

4

20

Small-scale

0.867

High

523197

SRC
Proto-oncogene tyrosine-protein kinase Src

3

15

Small-scale

0.867

High

209187

NCK2
Cytoplasmic protein NCK2

3

20

High-throughput

0.861

High

1219685

RHG12
Rho GTPase-activating protein 12

3

14

High-throughput

0.839

High

1255744

ASAP3
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3

2

14

High-throughput

0.811

High

823513

PAXI
Paxillin

2

4

Small-scale

0.789

High

581076

PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

1

2

High-throughput

0.770

High

412404

FYN
Tyrosine-protein kinase Fyn

2

15

Small-scale

0.768

High

442894

HCK
Tyrosine-protein kinase HCK

2

15

Small-scale

0.768

High

557823

NCK1
SH2/SH3 adapter protein NCK1

2

20

Small-scale

0.768

High

913181

ARF6
ADP-ribosylation factor 6

2

15

Small-scale

0.768

High

1356880

PACN2
Protein kinase C and casein kinase substrate in neurons protein 2

2

7

Small-scale

0.768

High

1356881

CD2AP
CD2-associated protein

2

20

Small-scale

0.743

High

256716

RFIP3
Rab11 family-interacting protein 3

1

6

Small-scale

0.724

High

950577

ARF1
ADP-ribosylation factor 1

1

14

Small-scale

0.692

High

802918

CRKL
Crk-like protein

1

20

High-throughput

0.691

High

476557

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

8

Small-scale

0.665

High

207845

PPIP1
Proline-serine-threonine phosphatase-interacting protein 1

1

7

Small-scale

0.647

High

275240

GRAP2
GRB2-related adapter protein 2

1

20

Small-scale

0.647

High

789012

TEC
Tyrosine-protein kinase Tec

1

15

Small-scale

0.647

High

1021587

DLG1
Disks large homolog 1

1

10

Small-scale

0.647

High

1270628

STAM1
Signal transducing adapter molecule 1

1

10

Small-scale

0.647

High

1307440

SH3G2
Endophilin-A1

1

11

Small-scale

0.647

High

626286

APC
Adenomatous polyposis coli protein

2

8

Small-scale

0.625

High

337590

ABL1
Tyrosine-protein kinase ABL1

1

15

High-throughput

0.618

High

508262

FGFR1
Fibroblast growth factor receptor 1

1

20

High-throughput

0.618

High

892677

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.618

High

925724

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.618

High

1075820

CIP4
Cdc42-interacting protein 4

1

8

Small-scale

0.618

High

1105499

LRRK1
Leucine-rich repeat serine/threonine-protein kinase 1

1

1

High-throughput

0.618

High

1262764

ARAP3
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3

1

19

Small-scale

0.618

High

1273297

ARHG2
Rho guanine nucleotide exchange factor 2

1

11

Small-scale

0.618

High

1310479

RHG09
Rho GTPase-activating protein 9

1

12

High-throughput

0.618

High

1316001

PACN1
Protein kinase C and casein kinase substrate in neurons protein 1

1

10

Small-scale

0.618

High

1356556

PACN3
Protein kinase C and casein kinase substrate in neurons protein 3

1

6

Small-scale

0.618

High

173623

NPHP1
Nephrocystin-1

1

0

Small-scale

0.614

High

1356882

SNX9
Sorting nexin-9

1

0

Small-scale

0.614

High

1088156

DDR2
Discoidin domain-containing receptor 2

1

20

High-throughput

0.578

High

385705

NTRK1
High affinity nerve growth factor receptor

1

20

High-throughput

0.553

High

608185

FGFR4
Fibroblast growth factor receptor 4

1

20

High-throughput

0.553

High

987307

TYRO3
Tyrosine-protein kinase receptor TYRO3

1

19

High-throughput

0.553

High

1172234

TRI67
Tripartite motif-containing protein 67

1

11

High-throughput

0.553

High

1203308

FCSD1
F-BAR and double SH3 domains protein 1

1

12

Small-scale

0.553

High

258244

DNJB6
DnaJ homolog subfamily B member 6

1

1

High-throughput

0.541

High

1027630

CBLB
E3 ubiquitin-protein ligase CBL-B

1

9

Small-scale

0.534

High

610532

CBL
E3 ubiquitin-protein ligase CBL

1

9

Small-scale

0.515

High

1349976

NHSL3
NHS-like protein 3

1

10

High-throughput

0.489

High

547273

EZRI
Ezrin

1

6

High-throughput

0.479

High

655502

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

11

High-throughput

0.479

High

909315

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

2

High-throughput

0.479

High

983526

PTN12
Tyrosine-protein phosphatase non-receptor type 12

1

2

High-throughput

0.479

High

1167473

RFIP1
Rab11 family-interacting protein 1

1

10

Small-scale

0.479

High

1254311

BICD2
Protein bicaudal D homolog 2

1

1

High-throughput

0.479

High

522261

CADH1
Cadherin-1

1

0

High-throughput

0.458

High

1346351

EXOC1
Exocyst complex component 1

1

1

High-throughput

0.457

High

348211

MYC
Myc proto-oncogene protein

1

3

High-throughput

0.437

High

489338

H14
Histone H1.4

1

3

High-throughput

0.437

High

1170245

PEAK3
Protein PEAK3

1

2

Small-scale

0.437

High

1185272

RFIP2
Rab11 family-interacting protein 2

1

13

Small-scale

0.437

High

123341

CBX4
E3 SUMO-protein ligase CBX4

1

3

High-throughput

0.407

High


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Last updated: 15 Jul 2024