Protein: ENL
Protein ENL (YEATS domain-containing protein 1)

Gene: ENL, MLLT1
Organism: Homo sapiens
Interactions: 99
UniProt ID: Q03111

Gene Ontology (top 5):
GO:0001650 - fibrillar center
GO:0003682 - chromatin binding
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0008023 - transcription elongation factor complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

850806

AFF1
AF4/FMR2 family member 1

8

15

Small-scale

0.970

High

974525

AFF4
AF4/FMR2 family member 4

7

16

Small-scale

0.970

High

788026

AF9
Protein AF-9

6

10

Small-scale

0.940

High

841666

CDK9
Cyclin-dependent kinase 9

14

17

Small-scale

0.761

High

130155

ELL2
RNA polymerase II elongation factor ELL2

4

15

Small-scale

0.699

High

974506

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

4

3

Small-scale

0.694

High

850830

AFF3
AF4/FMR2 family member 3

1

16

High-throughput

0.691

High

974491

BCOR
BCL-6 corepressor

3

11

Small-scale

0.667

High

974509

EAF1
ELL-associated factor 1

3

1

High-throughput

0.667

High

974520

ELL3
RNA polymerase II elongation factor ELL3

3

10

High-throughput

0.667

High

974521

CBX8
Chromobox protein homolog 8

3

12

Small-scale

0.661

High

876561

AF10
Protein AF-10

3

11

Small-scale

0.658

High

204651

E41L2
Band 4.1-like protein 2

2

12

High-throughput

0.628

High

236752

CCNT1
Cyclin-T1

2

8

Small-scale

0.628

High

685917

ARRB2
Beta-arrestin-2

2

2

High-throughput

0.628

High

817656

PI42A
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha

2

1

High-throughput

0.628

High

974495

YAF2
YY1-associated factor 2

2

2

High-throughput

0.628

High

974498

RYBP
RING1 and YY1-binding protein

2

2

High-throughput

0.628

High

974513

PCGF1
Polycomb group RING finger protein 1

2

13

Small-scale

0.628

High

974517

DEN2D
DENN domain-containing protein 2D

2

1

High-throughput

0.628

High

974499

PAF1
RNA polymerase II-associated factor 1 homolog

2

2

Small-scale

0.624

High

876636

ELL
RNA polymerase II elongation factor ELL

2

10

Small-scale

0.611

High

903148

WDR5
WD repeat-containing protein 5

2

9

Small-scale

0.585

High

917143

H4
Histone H4

2

9

Small-scale

0.584

High

974501

CAMKV
CaM kinase-like vesicle-associated protein

2

2

High-throughput

0.574

High

974505

BPIB1
BPI fold-containing family B member 1

2

1

High-throughput

0.574

High

369447

ESR1
Estrogen receptor

2

20

High-throughput

0.571

High

974507

ESR2
Estrogen receptor beta

2

20

High-throughput

0.571

High

717730

BMI1
Polycomb complex protein BMI-1

1

13

Small-scale

0.561

High

876592

AF17
Protein AF-17

2

10

Small-scale

0.558

High

237391

CCNT2
Cyclin-T2

1

8

High-throughput

0.536

High

666479

ARI4A
AT-rich interactive domain-containing protein 4A

1

3

High-throughput

0.536

High

928881

SKP1
S-phase kinase-associated protein 1

1

1

Small-scale

0.536

High

974481

KMT2A
Histone-lysine N-methyltransferase 2A

1

12

Small-scale

0.536

High

974488

ARI4B
AT-rich interactive domain-containing protein 4B

1

6

High-throughput

0.536

High

974497

PLCD3
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3

1

4

High-throughput

0.536

High

974510

CEP89
Centrosomal protein of 89 kDa

1

9

High-throughput

0.536

High

974512

PLCD4
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4

1

4

High-throughput

0.536

High

974516

E41L1
Band 4.1-like protein 1

1

13

High-throughput

0.536

High

974522

PKHJ1
Pleckstrin homology domain-containing family J member 1

1

5

High-throughput

0.536

High

974526

E41L3
Band 4.1-like protein 3

1

12

High-throughput

0.536

High

787720

HUTH
Histidine ammonia-lyase

1

0

High-throughput

0.513

High

974502

R3GEF
Guanine nucleotide exchange factor for Rab-3A

1

0

High-throughput

0.513

High

974503

SPP2B
Signal peptide peptidase-like 2B

1

0

High-throughput

0.513

High

559073

H15
Histone H1.5

1

6

Small-scale

0.501

High

974484

H31T
Histone H3.1t

1

20

Small-scale

0.501

High

974527

SYYM
Tyrosine--tRNA ligase, mitochondrial

1

0

High-throughput

0.493

High

661238

S10A2
Protein S100-A2

1

2

High-throughput

0.489

High

899619

FGF12
Fibroblast growth factor 12

1

2

High-throughput

0.489

High

974493

SPA12
Serpin A12

1

1

High-throughput

0.489

High

974500

SYT2
Synaptotagmin-2

1

3

High-throughput

0.489

High

843618

FXR1
RNA-binding protein FXR1

1

3

High-throughput

0.481

High

133450

NOP56
Nucleolar protein 56

1

4

High-throughput

0.479

High

151402

CHD1
Chromodomain-helicase-DNA-binding protein 1

1

8

Small-scale

0.479

High

170343

TIF1A
Transcription intermediary factor 1-alpha

1

15

High-throughput

0.479

High

179609

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

7

High-throughput

0.479

High

244313

BRD4
Bromodomain-containing protein 4

1

18

Small-scale

0.479

High

313419

MED26
Mediator of RNA polymerase II transcription subunit 26

1

1

High-throughput

0.479

High

430144

PROF1
Profilin-1

1

4

Small-scale

0.479

High

455341

PARP1
Poly [ADP-ribose] polymerase 1

1

8

High-throughput

0.479

High

555423

H2AX
Histone H2AX

1

11

Small-scale

0.479

High

569623

CEBPB
CCAAT/enhancer-binding protein beta

1

19

High-throughput

0.479

High

624869

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

3

Small-scale

0.479

High

750233

COIL
Coilin

1

2

High-throughput

0.479

High

817949

SOX2
Transcription factor SOX-2

1

17

High-throughput

0.479

High

828200

CENPA
Histone H3-like centromeric protein A

1

20

High-throughput

0.479

High

833867

CLK2
Dual specificity protein kinase CLK2

1

13

High-throughput

0.479

High

834023

CLK3
Dual specificity protein kinase CLK3

1

14

High-throughput

0.479

High

934112

CSK21
Casein kinase II subunit alpha

1

11

Small-scale

0.479

High

934679

H31
Histone H3.1

1

20

High-throughput

0.479

High

960272

CDK5
Cyclin-dependent kinase 5

1

6

High-throughput

0.479

High

964301

RUNX1
Runt-related transcription factor 1

1

7

High-throughput

0.479

High

974482

ACACA
Acetyl-CoA carboxylase 1

1

3

Small-scale

0.479

High

974486

H2B2E
Histone H2B type 2-E

1

16

Small-scale

0.479

High

974489

RN123
E3 ubiquitin-protein ligase RNF123

1

6

High-throughput

0.479

High

974490

CDC73
Parafibromin

1

5

Small-scale

0.479

High

974494

SMC5
Structural maintenance of chromosomes protein 5

1

10

High-throughput

0.479

High

974496

SLX4
Structure-specific endonuclease subunit SLX4

1

16

High-throughput

0.479

High

974508

SIR1
NAD-dependent protein deacetylase sirtuin-1

1

7

Small-scale

0.479

High

974511

RING2
E3 ubiquitin-protein ligase RING2

1

15

Small-scale

0.479

High

974514

DDX23
Probable ATP-dependent RNA helicase DDX23

1

10

High-throughput

0.479

High

974515

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

1

High-throughput

0.479

High

974518

EGLN3
Prolyl hydroxylase EGLN3

1

1

High-throughput

0.479

High

974519

SP110
Sp110 nuclear body protein

1

20

High-throughput

0.479

High

974524

CDK12
Cyclin-dependent kinase 12

1

15

High-throughput

0.479

High

974528

ZN330
Zinc finger protein 330

1

1

High-throughput

0.479

High

974529

SCC4
MAU2 chromatid cohesion factor homolog

1

1

High-throughput

0.479

High

974523

ALKB4
Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4

1

2

Small-scale

0.464

High

671211

RL12
Large ribosomal subunit protein uL11

1

0

Small-scale

0.458

High

817562

RFX5
DNA-binding protein RFX5

1

0

Small-scale

0.458

High

856656

RM12
Large ribosomal subunit protein bL12m

1

0

Small-scale

0.458

High

833715

CLK1
Dual specificity protein kinase CLK1

1

16

High-throughput

0.437

High

974483

CDK10
Cyclin-dependent kinase 10

1

7

High-throughput

0.437

High

974485

H2A2C
Histone H2A type 2-C

1

11

Small-scale

0.437

High

974492

TRI67
Tripartite motif-containing protein 67

1

7

High-throughput

0.437

High

974504

SP7
Transcription factor Sp7

1

20

High-throughput

0.437

High

303900

YIF1A
Protein YIF1A

2

0

High-throughput

0.316

High

124327

RFXAP
Regulatory factor X-associated protein

1

0

Small-scale

0.249

Low

974487

Q2Q440
MLL/ENL fusion protein

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024