Protein: CDN2C
Cyclin-dependent kinase 4 inhibitor C (Cyclin-dependent kinase 6 inhibitor) (p18-INK4c) (p18-INK6)

Gene: CDN2C, CDKN2C
Organism: Homo sapiens
Interactions: 96
UniProt ID: P42773

Gene Ontology (top 5):
GO:0000079 - regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0004861 - cyclin-dependent protein serine/threonine kinase inhibitor activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

515365

CDK4
Cyclin-dependent kinase 4

20

17

Small-scale

0.992

High

790967

CDK6
Cyclin-dependent kinase 6

20

17

Small-scale

0.991

High

790969

REL
Proto-oncogene c-Rel

3

9

High-throughput

0.881

High

235484

VINEX
Vinexin

2

18

High-throughput

0.783

High

790994

ANR44
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B

3

16

High-throughput

0.770

High

790915

CDN2B
Cyclin-dependent kinase 4 inhibitor B

2

15

High-throughput

0.768

High

790973

ATM
Serine-protein kinase ATM

1

8

Small-scale

0.724

High

790975

ATR
Serine/threonine-protein kinase ATR

1

7

Small-scale

0.724

High

386260

P53
Cellular tumor antigen p53

1

12

High-throughput

0.698

High

216463

SAHH2
S-adenosylhomocysteine hydrolase-like protein 1

5

0

High-throughput

0.694

High

551085

ITF2
Transcription factor 4

3

2

High-throughput

0.683

High

790998

HTF4
Transcription factor 12

3

2

High-throughput

0.683

High

791016

NAGK
N-acetyl-D-glucosamine kinase

3

1

High-throughput

0.683

High

622390

CCND1
G1/S-specific cyclin-D1

3

12

High-throughput

0.667

High

673129

CCND3
G1/S-specific cyclin-D3

3

12

High-throughput

0.667

High

791007

NIF3L
NIF3-like protein 1

2

2

High-throughput

0.654

High

373840

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

13

High-throughput

0.647

High

383676

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

20

High-throughput

0.647

High

557062

PGFRA
Platelet-derived growth factor receptor alpha

1

20

High-throughput

0.647

High

681718

AKT1
RAC-alpha serine/threonine-protein kinase

1

10

High-throughput

0.647

High

790957

MK08
Mitogen-activated protein kinase 8

1

15

Small-scale

0.647

High

790958

MP2K3
Dual specificity mitogen-activated protein kinase kinase 3

1

20

High-throughput

0.647

High

790960

MK10
Mitogen-activated protein kinase 10

1

15

Small-scale

0.647

High

790979

STK11
Serine/threonine-protein kinase STK11

1

2

High-throughput

0.647

High

791011

LATS2
Serine/threonine-protein kinase LATS2

1

12

High-throughput

0.647

High

790962

CASP6
Caspase-6

1

0

High-throughput

0.630

High

791014

COKA1

1

14

High-throughput

0.618

High

658832

MK01
Mitogen-activated protein kinase 1

1

10

High-throughput

0.618

High

790963

CDN2D
Cyclin-dependent kinase 4 inhibitor D

1

20

High-throughput

0.618

High

790989

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.618

High

790999

GA2L1
GAS2-like protein 1

2

8

High-throughput

0.611

High

197674

CRX
Cone-rod homeobox protein

2

15

High-throughput

0.606

High

790966

PO6F2
POU domain, class 6, transcription factor 2

2

7

High-throughput

0.606

High

790978

K1H1
Keratin, type I cuticular Ha1

2

12

High-throughput

0.606

High

790984

PKHG4
Puratrophin-1

2

10

High-throughput

0.606

High

791005

PBX4
Pre-B-cell leukemia transcription factor 4

2

1

High-throughput

0.606

High

791008

CTDS1
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1

2

3

High-throughput

0.606

High

351570

NEU2
Vasopressin-neurophysin 2-copeptin

2

0

High-throughput

0.602

High

687128

CDD
Cytidine deaminase

2

0

High-throughput

0.602

High

791001

PYM1
Partner of Y14 and mago

2

0

High-throughput

0.602

High

607910

FGFR4
Fibroblast growth factor receptor 4

1

20

High-throughput

0.579

High

665165

EPHA2
Ephrin type-A receptor 2

1

20

High-throughput

0.579

High

790970

MP2K5
Dual specificity mitogen-activated protein kinase kinase 5

1

19

High-throughput

0.579

High

790991

PRSR2
Proline and serine-rich protein 2

2

1

High-throughput

0.574

High

791010

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

2

Small-scale

0.561

High

233927

GDF9
Growth/differentiation factor 9

1

2

High-throughput

0.541

High

506495

ARY2
Arylamine N-acetyltransferase 2

1

1

High-throughput

0.541

High

790964

NH2L1
NHP2-like protein 1

1

1

High-throughput

0.541

High

790965

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

1

11

High-throughput

0.541

High

790968

TLE1
Transducin-like enhancer protein 1

1

6

High-throughput

0.541

High

790974

U119A
Protein unc-119 homolog A

1

2

High-throughput

0.541

High

790990

CSN6
COP9 signalosome complex subunit 6

1

3

High-throughput

0.541

High

791003

MTA3
Metastasis-associated protein MTA3

1

13

High-throughput

0.541

High

791009

GOPC
Golgi-associated PDZ and coiled-coil motif-containing protein

1

20

High-throughput

0.541

High

790980

EZH2
Histone-lysine N-methyltransferase EZH2

1

18

High-throughput

0.536

High

790996

RIN3
Ras and Rab interactor 3

1

9

High-throughput

0.536

High

791018

GPSM3
G-protein-signaling modulator 3

1

1

High-throughput

0.536

High

790976

NC2A
Dr1-associated corepressor

1

0

High-throughput

0.518

High

124377

HIP1
Huntingtin-interacting protein 1

1

6

High-throughput

0.515

High

263549

PR40A
Pre-mRNA-processing factor 40 homolog A

1

13

High-throughput

0.515

High

394281

A4
Amyloid-beta precursor protein

1

6

High-throughput

0.515

High

790977

ACOX1
Peroxisomal acyl-coenzyme A oxidase 1

1

0

High-throughput

0.513

High

791002

SPXN
Spexin

1

0

High-throughput

0.513

High

791012

BEX4
Protein BEX4

1

0

High-throughput

0.513

High

790993

LNX2
Ligand of Numb protein X 2

1

20

High-throughput

0.512

High

346158

MYC
Myc proto-oncogene protein

1

17

High-throughput

0.501

High

475454

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

14

High-throughput

0.501

High

624560

CCNE1
G1/S-specific cyclin-E1

1

3

High-throughput

0.501

High

649061

ARNT
Aryl hydrocarbon receptor nuclear translocator

1

7

High-throughput

0.501

High

673036

CCND2
G1/S-specific cyclin-D2

1

9

High-throughput

0.501

High

719404

MERL
Merlin

1

20

High-throughput

0.501

High

790971

GRM1
Metabotropic glutamate receptor 1

1

3

High-throughput

0.501

High

790959

APLP1
Amyloid beta precursor like protein 1

1

6

High-throughput

0.494

High

791004

ANGL4
Angiopoietin-related protein 4

1

2

High-throughput

0.494

High

791006

CC90B
Coiled-coil domain-containing protein 90B, mitochondrial

1

1

High-throughput

0.494

High

791019

ST14
Suppressor of tumorigenicity 14 protein

1

1

High-throughput

0.494

High

790985

PPM1J
Protein phosphatase 1J

1

1

High-throughput

0.489

High

790997

SYMM
Methionine--tRNA ligase, mitochondrial

1

2

High-throughput

0.489

High

791017

AT7L1
Ataxin-7-like protein 1

1

10

High-throughput

0.489

High

790702

CDN2A
Cyclin-dependent kinase inhibitor 2A

1

16

High-throughput

0.479

High

790961

KAD2
Adenylate kinase 2, mitochondrial

1

6

High-throughput

0.479

High

790981

CDC37
Hsp90 co-chaperone Cdc37

1

6

High-throughput

0.479

High

791015

UBQL2
Ubiquilin-2

1

8

High-throughput

0.479

High

527334

LAMP2
Lysosome-associated membrane glycoprotein 2

1

5

High-throughput

0.470

High

790995

MTMRE
Myotubularin-related protein 14

1

0

High-throughput

0.458

High

790988

RIF1
Telomere-associated protein RIF1

1

18

High-throughput

0.457

High

791000

SLX1
Structure-specific endonuclease subunit SLX1

2

0

High-throughput

0.328

High

790972

SG2A2
Mammaglobin-A

1

0

High-throughput

0.282

High

790983

GREB1
Protein GREB1

1

0

High-throughput

0.282

High

790986

RBM48
RNA-binding protein 48

1

0

High-throughput

0.282

High

791020

LY96
Lymphocyte antigen 96

1

0

High-throughput

0.282

High

454080

GIP
Gastric inhibitory polypeptide

1

0

High-throughput

0.279

Low

790982

CART

1

0

High-throughput

0.279

Low

790992

DAAF8
Dynein axonemal assembly factor 8

1

0

High-throughput

0.279

Low

790987

LRIF1
Ligand-dependent nuclear receptor-interacting factor 1

1

0

High-throughput

0.251

Low

791013

QPCTL
Glutaminyl-peptide cyclotransferase-like protein

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024