Protein: STAT3
Signal transducer and activator of transcription 3 (Acute-phase response factor)

Gene: STAT3
Organism: Homo sapiens
Interactions: 456
UniProt ID: P40763

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000976 - transcription cis-regulatory region binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

338060

EGFR
Epidermal growth factor receptor

20

20

Small-scale

0.989

High

776593

STAT1
Signal transducer and activator of transcription 1-alpha/beta

12

17

Small-scale

0.978

High

776589

STAT3
Signal transducer and activator of transcription 3

13

16

Small-scale

0.974

High

238377

JAK2
Tyrosine-protein kinase JAK2

11

20

Small-scale

0.972

High

776617

BMX
Cytoplasmic tyrosine-protein kinase BMX

8

15

Small-scale

0.966

High

570489

PTN2
Tyrosine-protein phosphatase non-receptor type 2

7

18

Small-scale

0.959

High

776598

KSYK
Tyrosine-protein kinase SYK

6

20

Small-scale

0.949

High

522829

SRC
Proto-oncogene tyrosine-protein kinase Src

6

15

Small-scale

0.947

High

776611

BLK
Tyrosine-protein kinase Blk

5

15

High-throughput

0.925

High

616754

JAK1
Tyrosine-protein kinase JAK1

5

20

Small-scale

0.912

High

776596

MTOR
Serine/threonine-protein kinase mTOR

4

3

Small-scale

0.904

High

383662

ERBB2
Receptor tyrosine-protein kinase erbB-2

4

20

Small-scale

0.881

High

434150

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

3

20

Small-scale

0.847

High

776659

PTN11
Tyrosine-protein phosphatase non-receptor type 11

3

18

Small-scale

0.827

High

411624

LCK
Tyrosine-protein kinase Lck

3

15

Small-scale

0.827

High

573602

PTN1
Tyrosine-protein phosphatase non-receptor type 1

2

18

Small-scale

0.818

High

776682

LRC32
Transforming growth factor beta activator LRRC32

2

1

High-throughput

0.811

High

201250

M3K7
Mitogen-activated protein kinase kinase kinase 7

2

4

Small-scale

0.802

High

454804

FGR
Tyrosine-protein kinase Fgr

2

16

Small-scale

0.767

High

129229

P85B
Phosphatidylinositol 3-kinase regulatory subunit beta

2

20

High-throughput

0.767

High

655247

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

2

4

High-throughput

0.767

High

776597

ABL2
Tyrosine-protein kinase ABL2

2

14

High-throughput

0.767

High

776765

P55G
Phosphatidylinositol 3-kinase regulatory subunit gamma

2

20

High-throughput

0.767

High

776824

SH22A
SH2 domain-containing protein 2A

2

16

High-throughput

0.767

High

776665

EP300
Histone acetyltransferase p300

11

13

Small-scale

0.755

High

433628

LYN
Tyrosine-protein kinase Lyn

2

15

Small-scale

0.755

High

435568

IGF1R
Insulin-like growth factor 1 receptor

2

14

Small-scale

0.754

High

770182

IL6RB
Interleukin-6 receptor subunit beta

2

8

Small-scale

0.754

High

146671

SOCS7
Suppressor of cytokine signaling 7

1

18

Small-scale

0.740

High

776871

PIAS3
E3 SUMO-protein ligase PIAS3

7

4

Small-scale

0.737

High

776658

KPCD
Protein kinase C delta type

1

7

Small-scale

0.724

High

776695

CIP4
Cdc42-interacting protein 4

1

2

Small-scale

0.724

High

776655

TF65
Transcription factor p65

5

5

Small-scale

0.713

High

199536

M3K13
Mitogen-activated protein kinase kinase kinase 13

1

5

High-throughput

0.698

High

776594

STAT6
Signal transducer and activator of transcription 6

1

16

High-throughput

0.698

High

776603

PA24A
Cytosolic phospholipase A2

1

2

High-throughput

0.691

High

776777

SPSB4
SPRY domain-containing SOCS box protein 4

1

7

High-throughput

0.691

High

434992

SP1
Transcription factor Sp1

4

4

Small-scale

0.691

High

776674

HDAC1
Histone deacetylase 1

4

10

Small-scale

0.687

High

776704

HIF1A
Hypoxia-inducible factor 1-alpha

4

6

Small-scale

0.683

High

487197

ANDR
Androgen receptor

4

18

Small-scale

0.680

High

377158

GCR
Glucocorticoid receptor

4

19

Small-scale

0.676

High

177219

HDAC3
Histone deacetylase 3

4

10

Small-scale

0.676

High

501008

IRF1
Interferon regulatory factor 1

4

20

Small-scale

0.676

High

552122

RFA2
Replication protein A 32 kDa subunit

3

2

Small-scale

0.666

High

776620

JAK3
Tyrosine-protein kinase JAK3

1

20

Small-scale

0.665

High

622380

CCND1
G1/S-specific cyclin-D1

3

5

Small-scale

0.664

High

234483

DSCAM
Cell adhesion molecule DSCAM

1

0

High-throughput

0.663

High

776745

I22R1
Interleukin-22 receptor subunit alpha-1

3

14

Small-scale

0.661

High

776599

MK08
Mitogen-activated protein kinase 8

3

8

Small-scale

0.660

High

776716

VASN
Vasorin

1

0

High-throughput

0.656

High

776807

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

3

5

High-throughput

0.654

High

412065

FYN
Tyrosine-protein kinase Fyn

1

15

Small-scale

0.647

High

442788

HCK
Tyrosine-protein kinase HCK

1

15

Small-scale

0.647

High

500951

GHR
Growth hormone receptor

1

20

Small-scale

0.647

High

776836

PHAG1
Phosphoprotein associated with glycosphingolipid-enriched microdomains 1

1

3

Small-scale

0.646

High

776865

TRAF6
TNF receptor-associated factor 6

3

7

Small-scale

0.640

High

675303

SORCN
Sorcin

2

3

Small-scale

0.640

High

274069

XRP2
Protein XRP2

3

0

High-throughput

0.638

High

776692

TCAL1
Transcription elongation factor A protein-like 1

3

0

High-throughput

0.638

High

776827

TRPV5
Transient receptor potential cation channel subfamily V member 5

3

0

High-throughput

0.638

High

776870

CCG2
Voltage-dependent calcium channel gamma-2 subunit

3

0

High-throughput

0.638

High

776724

Q6ZVU3
cDNA FLJ42079 fis, clone SYNOV2021320, highly similar to SH3 DOMAIN-BINDING PROTEIN 3BP-2

1

1

High-throughput

0.637

High

776787

BICD1
Protein bicaudal D homolog 1

2

2

High-throughput

0.631

High

776851

I20RA
Interleukin-20 receptor subunit alpha

2

20

High-throughput

0.628

High

776638

GRB2
Growth factor receptor-bound protein 2

1

12

Small-scale

0.625

High

776798

CSF3R
Granulocyte colony-stimulating factor receptor

1

8

Small-scale

0.625

High

569321

CEBPB
CCAAT/enhancer-binding protein beta

2

8

Small-scale

0.624

High

668483

PML
Protein PML

2

13

Small-scale

0.624

High

776684

HIC1
Hypermethylated in cancer 1 protein

2

2

Small-scale

0.624

High

776697

NCOA1
Nuclear receptor coactivator 1

2

10

Small-scale

0.624

High

776643

3BP2
SH3 domain-binding protein 2

1

1

High-throughput

0.621

High

776747

CE120
Centrosomal protein of 120 kDa

1

5

High-throughput

0.621

High

776810

IKBZ
NF-kappa-B inhibitor zeta

2

8

Small-scale

0.619

High

146922

PTPRT
Receptor-type tyrosine-protein phosphatase T

1

1

Small-scale

0.618

High

147400

SOCS3
Suppressor of cytokine signaling 3

1

20

Small-scale

0.618

High

232798

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

1

2

High-throughput

0.618

High

373819

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

5

High-throughput

0.618

High

384414

NTRK1
High affinity nerve growth factor receptor

1

19

High-throughput

0.618

High

397144

KPCG
Protein kinase C gamma type

1

8

Small-scale

0.618

High

411328

INSR
Insulin receptor

1

15

Small-scale

0.618

High

426949

FES
Tyrosine-protein kinase Fes/Fps

1

17

Small-scale

0.618

High

441455

MET
Hepatocyte growth factor receptor

1

17

Small-scale

0.618

High

507894

FGFR1
Fibroblast growth factor receptor 1

1

16

Small-scale

0.618

High

562528

IL7RA
Interleukin-7 receptor subunit alpha

1

2

High-throughput

0.618

High

572592

VGFR1
Vascular endothelial growth factor receptor 1

1

13

Small-scale

0.618

High

601474

FGFR2
Fibroblast growth factor receptor 2

1

19

Small-scale

0.618

High

665813

PTN6
Tyrosine-protein phosphatase non-receptor type 6

1

13

Small-scale

0.618

High

729621

VGFR2
Vascular endothelial growth factor receptor 2

1

13

Small-scale

0.618

High

776595

STA5A
Signal transducer and activator of transcription 5A

1

16

Small-scale

0.618

High

776615

STA5B
Signal transducer and activator of transcription 5B

1

16

Small-scale

0.618

High

776621

STAT2
Signal transducer and activator of transcription 2

1

16

Small-scale

0.618

High

776626

EPHA5
Ephrin type-A receptor 5

1

12

Small-scale

0.618

High

776629

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

3

High-throughput

0.618

High

776649

IRF9
Interferon regulatory factor 9

1

20

Small-scale

0.618

High

776653

ROR1
Inactive tyrosine-protein kinase transmembrane receptor ROR1

1

20

Small-scale

0.618

High

776657

FAK1
Focal adhesion kinase 1

1

20

Small-scale

0.618

High

776660

BTK
Tyrosine-protein kinase BTK

1

15

Small-scale

0.618

High

776680

FAK2
Protein-tyrosine kinase 2-beta

1

20

Small-scale

0.618

High

776687

STAT4
Signal transducer and activator of transcription 4

1

17

Small-scale

0.618

High

776722

TRI67
Tripartite motif-containing protein 67

1

10

High-throughput

0.618

High

776792

NED4L
E3 ubiquitin-protein ligase NEDD4-like

1

6

Small-scale

0.618

High

776831

SH2B1
SH2B adapter protein 1

1

14

Small-scale

0.618

High

776856

ALK
ALK tyrosine kinase receptor

1

20

Small-scale

0.618

High

776737

TRI59
Tripartite motif-containing protein 59

4

5

Small-scale

0.617

High

414457

PRGR
Progesterone receptor

2

17

Small-scale

0.612

High

589732

CAP7
Azurocidin

2

3

High-throughput

0.611

High

518601

IMDH2
Inosine-5'-monophosphate dehydrogenase 2

2

1

High-throughput

0.606

High

776788

P121A
Nuclear envelope pore membrane protein POM 121

2

4

High-throughput

0.606

High

776701

NF2L2
Nuclear factor erythroid 2-related factor 2

1

9

Small-scale

0.603

High

776793

CDK15
Cyclin-dependent kinase 15

2

0

High-throughput

0.602

High

641163

DNMT1
DNA

2

2

Small-scale

0.601

High

658824

MK01
Mitogen-activated protein kinase 1

2

5

Small-scale

0.601

High

776769

CBP
CREB-binding protein

2

14

Small-scale

0.595

High

776699

EZH2
Histone-lysine N-methyltransferase EZH2

2

1

Small-scale

0.594

High

235050

DOK2
Docking protein 2

2

2

High-throughput

0.594

High

610274

CBL
E3 ubiquitin-protein ligase CBL

2

3

High-throughput

0.594

High

776605

MAPK2
MAP kinase-activated protein kinase 2

2

3

High-throughput

0.594

High

776654

PPARD
Peroxisome proliferator-activated receptor delta

2

16

High-throughput

0.594

High

776688

LASP1
LIM and SH3 domain protein 1

2

1

High-throughput

0.594

High

776696

TWST1
Twist-related protein 1

2

2

High-throughput

0.594

High

776708

ZN829
Zinc finger protein 829

2

2

High-throughput

0.594

High

776712

TASO2
Protein TASOR 2

2

1

High-throughput

0.594

High

776726

DOK3
Docking protein 3

2

2

High-throughput

0.594

High

776741

WDFY3
WD repeat and FYVE domain-containing protein 3

2

1

High-throughput

0.594

High

776789

VPS39
Vam6/Vps39-like protein

2

1

High-throughput

0.594

High

776832

BRWD1
Bromodomain and WD repeat-containing protein 1

2

5

High-throughput

0.594

High

776847

HESX1
Homeobox expressed in ES cells 1

2

1

High-throughput

0.594

High

776861

ZN281
Zinc finger protein 281

2

1

High-throughput

0.594

High

776795

ERBIN
Erbin

1

0

High-throughput

0.589

High

369122

ESR1
Estrogen receptor

2

20

Small-scale

0.586

High

776733

SIAH1
E3 ubiquitin-protein ligase SIAH1

2

1

Small-scale

0.586

High

776775

FBXW7
F-box/WD repeat-containing protein 7

2

4

Small-scale

0.586

High

776841

MYOF
Myoferlin

1

0

Small-scale

0.586

High

776857

DD19B
ATP-dependent RNA helicase DDX19B

2

0

High-throughput

0.585

High

125207

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

2

6

Small-scale

0.584

High

226735

PRKN
E3 ubiquitin-protein ligase parkin

2

2

High-throughput

0.584

High

244052

BRD4
Bromodomain-containing protein 4

2

4

Small-scale

0.584

High

345357

FOS
Protein c-Fos

2

11

Small-scale

0.584

High

431614

HS90A
Heat shock protein HSP 90-alpha

2

5

Small-scale

0.584

High

671738

PDIA3
Protein disulfide-isomerase A3

2

2

Small-scale

0.584

High

758139

CDN1A
Cyclin-dependent kinase inhibitor 1

2

1

Small-scale

0.584

High

776796

UBP28
Ubiquitin carboxyl-terminal hydrolase 28

2

7

Small-scale

0.584

High

232028

KDM1A
Lysine-specific histone demethylase 1A

1

3

Small-scale

0.578

High

776600

MK09
Mitogen-activated protein kinase 9

1

7

Small-scale

0.578

High

776610

CDK9
Cyclin-dependent kinase 9

1

7

Small-scale

0.578

High

776612

SMCA4
Transcription activator BRG1

1

5

Small-scale

0.578

High

776670

TIF1B
Transcription intermediary factor 1-beta

1

11

Small-scale

0.578

High

776683

HES1
Transcription factor HES-1

1

3

Small-scale

0.578

High

166500

NACAD
NAC-alpha domain-containing protein 1

2

2

High-throughput

0.576

High

579175

ATF3
Cyclic AMP-dependent transcription factor ATF-3

2

14

High-throughput

0.576

High

776591

MNDA
Myeloid cell nuclear differentiation antigen

2

1

High-throughput

0.576

High

776748

ZN557
Zinc finger protein 557

2

2

High-throughput

0.576

High

776760

CTF18
Chromosome transmission fidelity protein 18 homolog

2

1

High-throughput

0.576

High

776826

NXT2
NTF2-related export protein 2

2

1

High-throughput

0.576

High

776829

BATF3
Basic leucine zipper transcriptional factor ATF-like 3

2

13

High-throughput

0.576

High

776852

KLF15
Krueppel-like factor 15

2

5

High-throughput

0.576

High

609197

FGFR3
Fibroblast growth factor receptor 3

1

20

Small-scale

0.575

High

776663

DDR1
Epithelial discoidin domain-containing receptor 1

1

19

Small-scale

0.575

High

776833

TB22B
TBC1 domain family member 22B

2

1

High-throughput

0.574

High

157300

BCKD
Branched-chain alpha-ketoacid dehydrogenase kinase

1

2

High-throughput

0.573

High

427856

CAN1
Calpain-1 catalytic subunit

1

3

High-throughput

0.573

High

611391

NR4A1
Nuclear receptor subfamily 4immunitygroup A member 1

1

19

High-throughput

0.573

High

678252

COR1A
Coronin-1A

1

1

High-throughput

0.573

High

776667

ECH1
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial

1

2

High-throughput

0.573

High

776717

ELP2
Elongator complex protein 2

1

5

Small-scale

0.573

High

776740

PELP1
Proline-, glutamic acid- and leucine-rich protein 1

1

11

Small-scale

0.573

High

638240

RBTN2
Rhombotin-2

1

3

High-throughput

0.573

High

716573

CAH8
Carbonic anhydrase-related protein

2

0

High-throughput

0.569

High

776633

KR107
Keratin-associated protein 10-7

2

0

High-throughput

0.569

High

776728

NUFP2
FMR1-interacting protein NUFIP2

2

0

High-throughput

0.569

High

776731

PAQR7
Membrane progestin receptor alpha

2

0

High-throughput

0.569

High

776749

GSTCD
Glutathione S-transferase C-terminal domain-containing protein

2

0

High-throughput

0.569

High

776834

CCD87
Coiled-coil domain-containing protein 87

2

0

High-throughput

0.569

High

776863

RBGP1
Rab GTPase-activating protein 1

2

0

High-throughput

0.569

High

776864

DTNA
Dystrobrevin alpha

2

0

High-throughput

0.569

High

776753

G45IP
Large ribosomal subunit protein mL64

2

0

Small-scale

0.566

High

401561

JUN
Transcription factor Jun

1

12

Small-scale

0.561

High

545944

MYOD1
Myoblast determination protein 1

1

3

Small-scale

0.561

High

587458

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

10

Small-scale

0.561

High

776711

HES5
Transcription factor HES-5

1

3

Small-scale

0.561

High

776743

TAB3
TGF-beta-activated kinase 1 and MAP3K7-binding protein 3

1

5

Small-scale

0.561

High

776784

SIR1
NAD-dependent protein deacetylase sirtuin-1

2

0

Small-scale

0.559

High

776759

SETD7
Histone-lysine N-methyltransferase SETD7

1

0

Small-scale

0.554

High

776639

RAC1
Ras-related C3 botulinum toxin substrate 1

1

1

Small-scale

0.552

High

776842

NDUAD
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13

1

1

Small-scale

0.552

High

776642

PA1B2
Platelet-activating factor acetylhydrolase IB subunit alpha2

2

0

High-throughput

0.551

High

776675

TDG
G/T mismatch-specific thymine DNA glycosylase

2

0

High-throughput

0.551

High

776790

CNDP2
Cytosolic non-specific dipeptidase

2

0

High-throughput

0.551

High

776602

RS9
Small ribosomal subunit protein uS4

1

0

High-throughput

0.549

High

776661

ST2A1
Sulfotransferase 2A1

1

0

High-throughput

0.549

High

776758

MORC4
MORC family CW-type zinc finger protein 4

1

0

High-throughput

0.549

High

776805

GNL3
Guanine nucleotide-binding protein-like 3

1

0

High-throughput

0.549

High

198795

HXC11
Homeobox protein Hox-C11

1

1

High-throughput

0.541

High

257456

CREST
Calcium-responsive transactivator

1

5

High-throughput

0.541

High

414200

RB
Retinoblastoma-associated protein

1

0

Small-scale

0.537

High

776797

SIN3A
Paired amphipathic helix protein Sin3a

1

0

Small-scale

0.537

High

776828

RPR1B
Regulation of nuclear pre-mRNA domain-containing protein 1B

1

0

Small-scale

0.537

High

362175

GLPA
Glycophorin-A

1

2

High-throughput

0.536

High

545078

PVR
Poliovirus receptor

1

1

High-throughput

0.536

High

621772

PRTN3
Myeloblastin

1

3

High-throughput

0.536

High

686607

CCR1
C-C chemokine receptor type 1

1

6

High-throughput

0.536

High

776646

SSBP2
Single-stranded DNA-binding protein 2

1

1

High-throughput

0.536

High

776702

C3AR
C3a anaphylatoxin chemotactic receptor

1

3

High-throughput

0.536

High

776735

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

1

High-throughput

0.536

High

776778

EFMT3
EEF1A lysine methyltransferase 3

1

3

High-throughput

0.536

High

776812

SEM4C
Semaphorin-4C

1

1

High-throughput

0.536

High

776853

PHF11
PHD finger protein 11

1

3

High-throughput

0.536

High

776866

RN115
E3 ubiquitin-protein ligase RNF115

1

1

High-throughput

0.536

High

776868

GPR45
Probable G-protein coupled receptor 45

1

4

High-throughput

0.536

High

718447

NOS2
Nitric oxide synthase, inducible

1

3

Small-scale

0.534

High

776671

NMI
N-myc-interactor

1

6

Small-scale

0.527

High

776854

OGDHL
2-oxoglutarate dehydrogenase-like, mitochondrial

1

2

High-throughput

0.523

High

776815

PHS2
Pterin-4-alpha-carbinolamine dehydratase 2

1

0

High-throughput

0.518

High

200093

DAPK3
Death-associated protein kinase 3

1

3

Small-scale

0.515

High

254454

ROCK2
Rho-associated protein kinase 2

1

1

Small-scale

0.515

High

548831

MCP
Membrane cofactor protein

1

2

Small-scale

0.515

High

776590

CCNF
Cyclin-F

1

1

High-throughput

0.515

High

776613

IRAK1
Interleukin-1 receptor-associated kinase 1

1

2

Small-scale

0.515

High

776648

NFKB2
Nuclear factor NF-kappa-B p100 subunit

1

10

Small-scale

0.515

High

394254

A4
Amyloid-beta precursor protein

1

2

High-throughput

0.515

High

776630

STX17
Syntaxin-17

1

0

High-throughput

0.513

High

776632

TIRAP
Toll/interleukin-1 receptor domain-containing adapter protein

1

0

High-throughput

0.513

High

776647

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

0

High-throughput

0.513

High

776714

MBLC2
Acyl-coenzyme A thioesterase MBLAC2

1

0

High-throughput

0.513

High

776730

KIF27
Kinesin-like protein KIF27

1

0

High-throughput

0.513

High

776821

PACC1
Proton-activated chloride channel

1

0

High-throughput

0.513

High

776830

MBNL1
Muscleblind-like protein 1

1

0

High-throughput

0.513

High

776835

EKI2
Ethanolamine kinase 2

1

0

High-throughput

0.513

High

776860

SSUH2
Protein SSUH2 homolog

1

0

High-throughput

0.513

High

776869

LRRF2
Leucine-rich repeat flightless-interacting protein 2

1

0

High-throughput

0.513

High

776848

DAXX
Death domain-associated protein 6

1

0

Small-scale

0.512

High

776679

FHL2
Four and a half LIM domains protein 2

1

2

Small-scale

0.508

High

414585

PTMA
Prothymosin alpha [Cleaved into: Prothymosin alpha, N-terminally processed; Thymosin alpha-1]

1

0

Small-scale

0.506

High

540449

IL2RB
Interleukin-2 receptor subunit beta

1

20

Small-scale

0.501

High

776616

KS6A3
Ribosomal protein S6 kinase alpha-3

1

2

Small-scale

0.501

High

776627

RAD
GTP-binding protein RAD

1

1

Small-scale

0.501

High

776645

GTF2I
General transcription factor II-I

1

1

Small-scale

0.501

High

776694

KS6A1
Ribosomal protein S6 kinase alpha-1

1

2

Small-scale

0.501

High

776785

RNF31
E3 ubiquitin-protein ligase RNF31

1

7

Small-scale

0.501

High

335058

DHE3
Glutamate dehydrogenase 1, mitochondrial

1

1

High-throughput

0.500

High

776664

LG3BP
Galectin-3-binding protein

1

1

High-throughput

0.500

High

776763

SYNE2
Nesprin-2

1

5

High-throughput

0.500

High

652774

APEX1
DNA repair nuclease/redox regulator APEX1

1

0

Small-scale

0.493

High

704249

DUT
Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial

1

0

High-throughput

0.493

High

776662

KHDR1
KH domain-containing, RNA-binding, signal transduction-associated protein 1

1

0

Small-scale

0.493

High

776689

NFIX
Nuclear factor 1 X-type

1

0

Small-scale

0.493

High

776838

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

1

0

High-throughput

0.493

High

776855

HECD1
E3 ubiquitin-protein ligase HECTD1

1

6

High-throughput

0.489

High

776844

NLK
Serine/threonine-protein kinase NLK

1

6

Small-scale

0.484

High

776867

RBM8A
RNA-binding protein 8A

1

1

Small-scale

0.484

High

199092

SIAH2
E3 ubiquitin-protein ligase SIAH2

1

3

High-throughput

0.481

High

311051

MPZL1
Myelin protein zero-like protein 1

1

1

High-throughput

0.481

High

363406

AMBP
Protein AMBP

1

2

High-throughput

0.481

High

385848

CPNS1
Calpain small subunit 1

1

3

High-throughput

0.481

High

428951

ADRB2
Beta-2 adrenergic receptor

1

2

Small-scale

0.481

High

550335

ZEP1
Zinc finger protein 40

1

1

High-throughput

0.481

High

776618

HNRPM
Heterogeneous nuclear ribonucleoprotein M

1

1

High-throughput

0.481

High

776606

TCPG
T-complex protein 1 subunit gamma

1

0

Small-scale

0.480

High

203442

MTG8R
Protein CBFA2T2

1

0

Small-scale

0.479

High

268415

BAF
Barrier-to-autointegration factor

1

0

High-throughput

0.479

High

685632

PRDX2
Peroxiredoxin-2

1

0

Small-scale

0.479

High

776804

HNRL1
Heterogeneous nuclear ribonucleoprotein U-like protein 1

1

0

High-throughput

0.479

High

133760

SOX1
Transcription factor SOX-1

1

1

Small-scale

0.479

High

146463

BHE40
Class E basic helix-loop-helix protein 40

1

3

Small-scale

0.479

High

148482

CTRO
Citron Rho-interacting kinase

1

2

High-throughput

0.479

High

158421

IKKB
Inhibitor of nuclear factor kappa-B kinase subunit beta

1

2

Small-scale

0.479

High

170287

TIF1A
Transcription intermediary factor 1-alpha

1

19

Small-scale

0.479

High

173854

MK13
Mitogen-activated protein kinase 13

1

8

Small-scale

0.479

High

344364

ANGT
Angiotensinogen

1

1

Small-scale

0.479

High

346128

MYC
Myc proto-oncogene protein

1

4

Small-scale

0.479

High

352918

IFNG
Interferon gamma

1

3

Small-scale

0.479

High

352990

IL1B
Interleukin-1 beta

1

1

Small-scale

0.479

High

361983

FIBG
Fibrinogen gamma chain

1

4

Small-scale

0.479

High

386236

P53
Cellular tumor antigen p53

1

3

High-throughput

0.479

High

388274

HSPB1
Heat shock protein beta-1

1

4

Small-scale

0.479

High

399996

ICAM1
Intercellular adhesion molecule 1

1

3

Small-scale

0.479

High

402807

REG1A
Lithostathine-1-alpha

1

1

Small-scale

0.479

High

427477

ANXA2
Annexin A2

1

1

Small-scale

0.479

High

436680

GLI1
Zinc finger protein GLI1

1

3

Small-scale

0.479

High

443377

VIME
Vimentin

1

4

Small-scale

0.479

High

445718

IL6RA
Interleukin-6 receptor subunit alpha

1

16

Small-scale

0.479

High

521777

CADH1
Cadherin-1

1

2

Small-scale

0.479

High

538136

ENPL
Endoplasmin

1

5

Small-scale

0.479

High

540802

PO2F1
POU domain, class 2, transcription factor 1

1

6

Small-scale

0.479

High

549562

VEGFA
Vascular endothelial growth factor A, long form

1

1

Small-scale

0.479

High

560491

TSHR
Thyrotropin receptor

1

2

Small-scale

0.479

High

561515

AT2A2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2

1

1

High-throughput

0.479

High

562895

STMN1
Stathmin

1

2

Small-scale

0.479

High

566010

INAR1
Interferon alpha/beta receptor 1

1

16

Small-scale

0.479

High

575312

EGR1
Early growth response protein 1

1

1

High-throughput

0.479

High

585416

E2AK2
Interferon-induced, double-stranded RNA-activated protein kinase

1

11

Small-scale

0.479

High

595663

BCL3
B-cell lymphoma 3 protein

1

8

Small-scale

0.479

High

595910

HNF1A
Hepatocyte nuclear factor 1-alpha

1

3

Small-scale

0.479

High

597370

PTN
Pleiotrophin

1

1

Small-scale

0.479

High

599626

TNAP3
Tumor necrosis factor alpha-induced protein 3

1

4

Small-scale

0.479

High

606838

IL10
Interleukin-10

1

1

Small-scale

0.479

High

622928

GA45A
Growth arrest and DNA damage-inducible protein GADD45 alpha

1

1

Small-scale

0.479

High

647492

MK03
Mitogen-activated protein kinase 3

1

5

Small-scale

0.479

High

650553

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.479

High

683880

1433S
14-3-3 protein sigma

1

1

High-throughput

0.479

High

701706

IL3RB
Cytokine receptor common subunit beta

1

17

Small-scale

0.479

High

719858

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.479

High

725376

COPB2
Coatomer subunit beta'

1

1

High-throughput

0.479

High

740112

NUP62
Nuclear pore glycoprotein p62

1

6

High-throughput

0.479

High

776592

CCR2
C-C chemokine receptor type 2

1

4

Small-scale

0.479

High

776601

MP2K3
Dual specificity mitogen-activated protein kinase kinase 3

1

6

Small-scale

0.479

High

776604

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

6

High-throughput

0.479

High

776608

VEGFC
Vascular endothelial growth factor C

1

1

Small-scale

0.479

High

776614

CCR5
C-C chemokine receptor type 5

1

6

Small-scale

0.479

High

776619

IMA5
Importin subunit alpha-5

1

3

Small-scale

0.479

High

776622

PLK1
Serine/threonine-protein kinase PLK1

1

3

Small-scale

0.479

High

776625

COPA
Coatomer subunit alpha

1

1

High-throughput

0.479

High

776634

1433G
14-3-3 protein gamma

1

1

High-throughput

0.479

High

776636

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

2

Small-scale

0.479

High

776640

RACK1
Small ribosomal subunit protein RACK1

1

6

Small-scale

0.479

High

776641

UBC9
SUMO-conjugating enzyme UBC9

1

1

High-throughput

0.479

High

776644

RNF4
E3 ubiquitin-protein ligase RNF4

1

6

High-throughput

0.479

High

776650

MDM2
E3 ubiquitin-protein ligase Mdm2

1

1

Small-scale

0.479

High

776652

IFM3
Interferon-induced transmembrane protein 3

1

4

Small-scale

0.479

High

776656

K1C17
Keratin, type I cytoskeletal 17

1

1

High-throughput

0.479

High

776666

FOXC1
Forkhead box protein C1

1

2

High-throughput

0.479

High

776669

TRI32
E3 ubiquitin-protein ligase TRIM32

1

6

Small-scale

0.479

High

776676

CUL3
Cullin-3

1

4

High-throughput

0.479

High

776677

CUL4A
Cullin-4A

1

4

High-throughput

0.479

High

776678

RUNX2
Runt-related transcription factor 2

1

1

Small-scale

0.479

High

776693

PTPA
Serine/threonine-protein phosphatase 2A activator

1

1

Small-scale

0.479

High

776698

SMAD1
Mothers against decapentaplegic homolog 1

1

2

Small-scale

0.479

High

776705

IF16
Gamma-interferon-inducible protein 16

1

1

Small-scale

0.479

High

776706

MICB
MHC class I polypeptide-related sequence B

1

1

Small-scale

0.479

High

776727

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

7

High-throughput

0.479

High

776729

NAA40
N-alpha-acetyltransferase 40

1

1

High-throughput

0.479

High

776734

LRC49
Leucine-rich repeat-containing protein 49

1

2

High-throughput

0.479

High

776736

Z3H7A
Zinc finger CCCH domain-containing protein 7A

1

1

High-throughput

0.479

High

776746

ARFG1
ADP-ribosylation factor GTPase-activating protein 1

1

1

High-throughput

0.479

High

776751

MAFA
Transcription factor MafA

1

3

Small-scale

0.479

High

776752

COP1
E3 ubiquitin-protein ligase COP1

1

5

Small-scale

0.479

High

776755

BICD2
Protein bicaudal D homolog 2

1

2

High-throughput

0.479

High

776757

RBCC1
RB1-inducible coiled-coil protein 1

1

5

High-throughput

0.479

High

776764

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

1

High-throughput

0.479

High

776767

ESR2
Estrogen receptor beta

1

19

High-throughput

0.479

High

776768

HDAC2
Histone deacetylase 2

1

11

Small-scale

0.479

High

776770

KAT2A
Histone acetyltransferase KAT2A

1

13

Small-scale

0.479

High

776771

KAT2B
Histone acetyltransferase KAT2B

1

8

Small-scale

0.479

High

776772

RAD50
DNA repair protein RAD50

1

1

High-throughput

0.479

High

776773

CSN5
COP9 signalosome complex subunit 5

1

3

Small-scale

0.479

High

776774

KAT5
Histone acetyltransferase KAT5

1

1

Small-scale

0.479

High

776779

SH3K1
SH3 domain-containing kinase-binding protein 1

1

1

High-throughput

0.479

High

776782

OPTN
Optineurin

1

3

High-throughput

0.479

High

776786

TRI11
E3 ubiquitin-protein ligase TRIM11

1

4

Small-scale

0.479

High

776791

SNX27
Sorting nexin-27

1

2

High-throughput

0.479

High

776809

HDAC8
Histone deacetylase 8

1

12

Small-scale

0.479

High

776814

WWTR1
WW domain-containing transcription regulator protein 1

1

7

High-throughput

0.479

High

776816

ATG5
Autophagy protein 5

1

1

High-throughput

0.479

High

776819

PKHA4
Pleckstrin homology domain-containing family A member 4

1

4

High-throughput

0.479

High

776822

TRI45
E3 ubiquitin-protein ligase TRIM45

1

16

Small-scale

0.479

High

776823

IL21
Interleukin-21

1

3

Small-scale

0.479

High

776825

IL1AP
Interleukin-1 receptor accessory protein

1

7

Small-scale

0.479

High

776843

SYLC
Leucine--tRNA ligase, cytoplasmic

1

1

High-throughput

0.479

High

776845

MAGC2
Melanoma-associated antigen C2

1

2

Small-scale

0.479

High

776846

HDAC6
Histone deacetylase 6

1

12

Small-scale

0.479

High

776849

ZRAN1
Ubiquitin thioesterase ZRANB1

1

8

High-throughput

0.479

High

776850

TES
Testin

1

4

High-throughput

0.479

High

776858

UBP22
Ubiquitin carboxyl-terminal hydrolase 22

1

6

Small-scale

0.479

High

671406

ECHM
Enoyl-CoA hydratase, mitochondrial

1

2

Small-scale

0.462

High

208326

SPY1
Protein sprouty homolog 1

1

0

High-throughput

0.460

High

382334

HLAA
HLA class I histocompatibility antigen, A alpha chain

1

0

High-throughput

0.460

High

776623

ARFP2
Arfaptin-2

1

0

High-throughput

0.460

High

776637

RL11
Large ribosomal subunit protein uL5

1

0

High-throughput

0.460

High

776738

ASXL1
Polycomb group protein ASXL1

1

0

High-throughput

0.460

High

776750

SP20H
Transcription factor SPT20 homolog

1

0

High-throughput

0.460

High

776762

FOG2
Zinc finger protein ZFPM2

1

0

High-throughput

0.460

High

776800

SCAFB
Protein SCAF11

1

0

High-throughput

0.460

High

776808

SRRT
Serrate RNA effector molecule homolog

1

0

High-throughput

0.460

High

776813

NIF3L
NIF3-like protein 1

1

0

High-throughput

0.460

High

124786

EIF3F
Eukaryotic translation initiation factor 3 subunit F

1

0

Small-scale

0.458

High

149569

COPE
Coatomer subunit epsilon

1

0

High-throughput

0.458

High

167858

NPC1
NPC intracellular cholesterol transporter 1

1

0

High-throughput

0.458

High

283410

SRP72
Signal recognition particle subunit SRP72

1

0

High-throughput

0.458

High

305211

NXPH2
Neurexophilin-2

1

0

High-throughput

0.458

High

318076

DIRA3
GTP-binding protein Di-Ras3

1

0

Small-scale

0.458

High

420658

LIPL
Lipoprotein lipase

1

0

Small-scale

0.458

High

483382

RGPD1
RANBP2-like and GRIP domain-containing protein 1

1

0

High-throughput

0.458

High

495483

THIO
Thioredoxin

1

0

Small-scale

0.458

High

555094

CD44
CD44 antigen

1

0

Small-scale

0.458

High

556800

CREB1
Cyclic AMP-responsive element-binding protein 1

1

0

Small-scale

0.458

High

672383

2AAB
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform

1

0

Small-scale

0.458

High

684472

STIP1
Stress-induced-phosphoprotein 1

1

0

High-throughput

0.458

High

718571

PHB1
Prohibitin 1

1

0

Small-scale

0.458

High

771798

VHL
von Hippel-Lindau disease tumor suppressor

1

0

Small-scale

0.458

High

776609

ENTP1
Ectonucleoside triphosphate diphosphohydrolase 1

1

0

Small-scale

0.458

High

776624

COPB
Coatomer subunit beta

1

0

High-throughput

0.458

High

776631

SIK1
Serine/threonine-protein kinase SIK1

1

0

Small-scale

0.458

High

776635

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

776672

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

1

0

Small-scale

0.458

High

776673

4EBP1
Eukaryotic translation initiation factor 4E-binding protein 1

1

0

Small-scale

0.458

High

776681

FZD2
Frizzled-2

1

0

Small-scale

0.458

High

776691

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

776700

ZFHX3
Zinc finger homeobox protein 3

1

0

Small-scale

0.458

High

776710

MARH8
E3 ubiquitin-protein ligase MARCHF8

1

0

Small-scale

0.458

High

776715

VIR
Protein virilizer homolog

1

0

High-throughput

0.458

High

776720

CTR9
RNA polymerase-associated protein CTR9 homolog

1

0

Small-scale

0.458

High

776723

TPGS1
Tubulin polyglutamylase complex subunit 1

1

0

High-throughput

0.458

High

776725

MOB3C
MOB kinase activator 3C

1

0

High-throughput

0.458

High

776744

RFLB
Refilin-B

1

0

High-throughput

0.458

High

776754

GSDMB
Gasdermin-B

1

0

Small-scale

0.458

High

776817

CHM4B
Charged multivesicular body protein 4b

1

0

High-throughput

0.458

High

776818

GOLP3
Golgi phosphoprotein 3

1

0

Small-scale

0.458

High

776820

HAUS4
HAUS augmin-like complex subunit 4

1

0

High-throughput

0.458

High

776837

PIHD1
PIH1 domain-containing protein 1

1

0

High-throughput

0.458

High

776840

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.458

High

335375

NB5R3
NADH-cytochrome b5 reductase 3

1

3

High-throughput

0.445

High

496480

TAU
Microtubule-associated protein tau

1

1

High-throughput

0.445

High

507548

PIM1
Serine/threonine-protein kinase pim-1

1

2

Small-scale

0.445

High

559007

H15
Histone H1.5

1

1

High-throughput

0.445

High

776651

E2F1
Transcription factor E2F1

1

1

High-throughput

0.445

High

776668

STK4
Serine/threonine-protein kinase 4

1

2

High-throughput

0.445

High

776685

PLSI
Plastin-1

1

6

High-throughput

0.445

High

776732

STING
Stimulator of interferon genes protein

1

4

Small-scale

0.445

High

776739

TRI22
E3 ubiquitin-protein ligase TRIM22

1

4

High-throughput

0.445

High

776794

NUDC1
NudC domain-containing protein 1

1

1

High-throughput

0.445

High

776799

CDC5L
Cell division cycle 5-like protein

1

1

High-throughput

0.445

High

776811

ZDHC5
Palmitoyltransferase ZDHHC5

1

2

High-throughput

0.445

High

776859

TBD2B
TBC1 domain family member 2B

1

4

High-throughput

0.445

High

776709

OCAD2
OCIA domain-containing protein 2

1

1

Small-scale

0.437

High

776839

OCAD1
OCIA domain-containing protein 1

1

1

Small-scale

0.437

High

124590

CLIC1
Chloride intracellular channel protein 1

1

0

High-throughput

0.426

High

426589

H10
Histone H1.0

1

0

High-throughput

0.426

High

528707

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.426

High

776686

KCTD2
BTB/POZ domain-containing protein KCTD2

1

0

High-throughput

0.426

High

776690

SUZ12
Polycomb protein SUZ12

1

0

Small-scale

0.426

High

776703

FSCN1
Fascin

1

0

High-throughput

0.426

High

776802

TMM43
Transmembrane protein 43

1

0

High-throughput

0.426

High

776756

MIPT3
TRAF3-interacting protein 1

1

2

High-throughput

0.417

High

776761

ZDH19
Palmitoyltransferase ZDHHC19

1

2

Small-scale

0.407

High

776719

F117B
Protein FAM117B

2

0

High-throughput

0.310

High

776783

T4S19
Transmembrane 4 L6 family member 19

2

0

High-throughput

0.310

High

776766

RT31
Small ribosomal subunit protein mS31

1

0

High-throughput

0.299

High

303664

OR2A4
Olfactory receptor 2A4

1

0

High-throughput

0.279

Low

776607

COMP
Cartilage oligomeric matrix protein

1

0

High-throughput

0.279

Low

776707

CR021
UPF0711 protein C18orf21

1

0

High-throughput

0.279

Low

776721

DLK2
Protein delta homolog 2

1

0

High-throughput

0.279

Low

776776

PIGT
GPI transamidase component PIG-T

1

0

High-throughput

0.279

Low

776780

SARAF
Store-operated calcium entry-associated regulatory factor

1

0

High-throughput

0.279

Low

776801

PLCA
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha

1

0

High-throughput

0.279

Low

776803

MMTA2
Multiple myeloma tumor-associated protein 2

1

0

High-throughput

0.279

Low

776781

S2536
Solute carrier family 25 member 36

1

0

High-throughput

0.261

Low

224905

ZNRD2
Protein ZNRD2

1

0

High-throughput

0.251

Low

776628

LAMB2
Laminin subunit beta-2

1

0

High-throughput

0.251

Low

776713

RNLS
Renalase

1

0

Small-scale

0.249

Low

776806

TMUB1
Transmembrane and ubiquitin-like domain-containing protein 1

1

0

Small-scale

0.249

Low

776862

AAR2
Protein AAR2 homolog

1

0

High-throughput

0.249

Low

776742

OFCC1
Orofacial cleft 1 candidate gene 1 protein

1

0

High-throughput

0.238

Low

263077

RM33
Large ribosomal subunit protein bL33m

1

0

High-throughput

0.232

Low

776718

AR26L
Putative ankyrin repeat domain-containing protein 26-like protein

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024