Protein: PPBI
Intestinal-type alkaline phosphatase (IAP) (Intestinal alkaline phosphatase) (EC 3.1.3.1)

Gene: PPBI, ALPI
Organism: Homo sapiens
Interactions: 70
UniProt ID: P09923

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0002020 - protease binding
GO:0004035 - alkaline phosphatase activity
GO:0005576 - extracellular region
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

398484

PPB1
Alkaline phosphatase, placental type

2

4

High-throughput

0.811

High

456391

PPBN
Alkaline phosphatase, germ cell type

2

4

High-throughput

0.811

High

456422

NT2NA
Notch homolog 2 N-terminal-like protein A

2

4

High-throughput

0.628

High

456402

ARF5
ADP-ribosylation factor 5

2

0

High-throughput

0.602

High

456431

RB39B
Ras-related protein Rab-39B

2

0

High-throughput

0.602

High

456394

ARL2
ADP-ribosylation factor-like protein 2

2

1

High-throughput

0.574

High

456451

DD19B
ATP-dependent RNA helicase DDX19B

2

2

High-throughput

0.574

High

160896

RAB7L
Ras-related protein Rab-7L1

1

1

High-throughput

0.536

High

456398

RAB38
Ras-related protein Rab-38

1

1

High-throughput

0.536

High

456403

RHOG
Rho-related GTP-binding protein RhoG

1

4

High-throughput

0.536

High

456405

HYAL2
Hyaluronidase-2

1

1

High-throughput

0.536

High

456406

SEM3B
Semaphorin-3B

1

1

High-throughput

0.536

High

456430

ARL8A
ADP-ribosylation factor-like protein 8A

1

2

High-throughput

0.536

High

456432

VMP1
Vacuole membrane protein 1

1

2

High-throughput

0.536

High

456435

NAR5
Ecto-ADP-ribosyltransferase 5

1

1

High-throughput

0.536

High

456400

KR108
Keratin-associated protein 10-8

1

8

High-throughput

0.523

High

456401

KR109
Keratin-associated protein 10-9

1

8

High-throughput

0.523

High

327255

NOE2
Noelin-2

1

0

High-throughput

0.513

High

397087

PAI1
Plasminogen activator inhibitor 1

1

0

High-throughput

0.513

High

456408

SCRB2
Lysosome membrane protein 2

1

0

High-throughput

0.513

High

456414

RHEB
GTP-binding protein Rheb

1

0

High-throughput

0.513

High

456420

NFXL1
NF-X1-type zinc finger protein NFXL1

1

0

High-throughput

0.513

High

456421

TBA1A
Tubulin alpha-1A chain

1

0

High-throughput

0.513

High

456427

NUBPL
Iron-sulfur cluster transfer protein NUBPL

1

0

High-throughput

0.513

High

456441

MTG2
Mitochondrial ribosome-associated GTPase 2

1

0

High-throughput

0.513

High

456445

ABCB6
ATP-binding cassette sub-family B member 6

1

0

High-throughput

0.513

High

456449

ABCF2
ATP-binding cassette sub-family F member 2

1

0

High-throughput

0.513

High

456450

S2513
Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial

1

0

High-throughput

0.513

High

456395

RFC5
Replication factor C subunit 5

1

1

High-throughput

0.489

High

456396

RFC3
Replication factor C subunit 3

1

1

High-throughput

0.489

High

456436

SFXN2
Sideroflexin-2

1

2

High-throughput

0.489

High

456437

SFXN3
Sideroflexin-3

1

2

High-throughput

0.489

High

456442

TPC
Mitochondrial thiamine pyrophosphate carrier

1

1

High-throughput

0.489

High

456447

ARL8B
ADP-ribosylation factor-like protein 8B

1

2

High-throughput

0.489

High

456452

ORNT1
Mitochondrial ornithine transporter 1

1

2

High-throughput

0.489

High

456443

NOD2
Nucleotide-binding oligomerization domain-containing protein 2

1

1

Small-scale

0.481

High

456410

NBR1
Next to BRCA1 gene 1 protein

1

1

High-throughput

0.479

High

456423

TOR2X
Prosalusin

1

3

High-throughput

0.479

High

456448

HDAC6
Histone deacetylase 6

1

3

High-throughput

0.479

High

456409

IF4A2
Eukaryotic initiation factor 4A-II

1

2

High-throughput

0.470

High

456446

T106B
Transmembrane protein 106B

1

0

High-throughput

0.458

High

456399

KR103
Keratin-associated protein 10-3

1

8

High-throughput

0.439

High

456404

KIF23
Kinesin-like protein KIF23

1

4

High-throughput

0.437

High

456413

KIF14
Kinesin-like protein KIF14

1

2

High-throughput

0.437

High

456429

TF3B
Transcription factor IIIB 90 kDa subunit

1

2

Small-scale

0.437

High

456433

AURKB
Aurora kinase B

1

2

High-throughput

0.437

High

456392

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

0

High-throughput

0.426

High

456426

MSPD2
Motile sperm domain-containing protein 2

1

0

High-throughput

0.426

High

401297

JUN
Transcription factor Jun

1

1

High-throughput

0.407

High

456415

TOR2A
Torsin-2A

1

3

High-throughput

0.407

High

456419

PKHA7
Pleckstrin homology domain-containing family A member 7

1

1

High-throughput

0.407

High

456425

RDH13
Retinol dehydrogenase 13

2

0

High-throughput

0.328

High

456440

TBB1
Tubulin beta-1 chain

2

0

High-throughput

0.328

High

456407

IRF5
Interferon regulatory factor 5

1

0

Small-scale

0.292

High

388171

HSPB1
Heat shock protein beta-1

1

0

High-throughput

0.282

High

128699

RTCA
RNA 3'-terminal phosphate cyclase

1

0

High-throughput

0.279

Low

456393

KTHY
Thymidylate kinase

1

0

High-throughput

0.279

Low

456397

PEX3
Peroxisomal biogenesis factor 3

1

0

High-throughput

0.279

Low

456411

SMC1A
Structural maintenance of chromosomes protein 1A

1

0

High-throughput

0.279

Low

456412

DPOD3
DNA polymerase delta subunit 3

1

0

High-throughput

0.279

Low

456416

SE1L3
Protein sel-1 homolog 3

1

0

High-throughput

0.279

Low

456418

DRS7B
Dehydrogenase/reductase SDR family member 7B

1

0

High-throughput

0.279

Low

456428

TM263
Transmembrane protein 263

1

0

High-throughput

0.279

Low

456434

S35E1
Solute carrier family 35 member E1

1

0

High-throughput

0.279

Low

456439

GHITM
Growth hormone-inducible transmembrane protein

1

0

High-throughput

0.279

Low

456444

MET14
N6-adenosine-methyltransferase non-catalytic subunit

1

0

High-throughput

0.279

Low

456417

VIR
Protein virilizer homolog

1

0

High-throughput

0.249

Low

456424

MINK1
Misshapen-like kinase 1

1

0

High-throughput

0.249

Low

456438

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

1

0

Small-scale

0.249

Low

135202

E2F3
Transcription factor E2F3

1

0

Small-scale

0.232

Low


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Last updated: 15 Jul 2024