HitPredict - High confidence protein-protein interactions

Protein: SPP2A
Signal peptide peptidase-like 2A (SPP-like 2A) (SPPL2a) (EC 3.4.23.-) (Intramembrane protease 3) (IMP-3) (Presenilin-like protein 2)

Gene: SPP2A, SPPL2A
Organism: Homo sapiens
Interactions: 7
UniProt ID: Q8TCT8

Gene Ontology (top 5):
GO:0005765 - lysosomal membrane
GO:0005770 - late endosome
GO:0005886 - plasma membrane
GO:0006509 - membrane protein ectodomain proteolysis
GO:0010803 - regulation of tumor necrosis factor-mediated signaling pathway

Download interactions: TXT MITAB-2.5

Interaction	Interactor	Experiments	Homologs	Category	Interaction Score	Confidence
226833	SGTA Small glutamine-rich tetratricopeptide repeat-containing protein alpha	4	0	High-throughput	0.675	High
127375	LEG8 Galectin-8	3	1	High-throughput	0.667	High
1350112	KI2L4 Killer cell immunoglobulin-like receptor 2DL4	1	0	High-throughput	0.513	High
1254763	TRI67 Tripartite motif-containing protein 67	1	2	High-throughput	0.437	High
626295	NFKB1 Nuclear factor NF-kappa-B p105 subunit	1	0	High-throughput	0.282	High
301587	WFS1 Wolframin	1	0	High-throughput	0.268	Low
831104	CCNF Cyclin-F	1	0	High-throughput	0.249	Low

Service provided by Combinatics, Japan

Last updated: 11Aug2025