Protein: DOCK5
Dedicator of cytokinesis protein 5

Gene: DOCK5
Organism: Homo sapiens
Interactions: 109
UniProt ID: Q9H7D0

Gene Ontology (top 5):
GO:0002102 - podosome
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005096 - GTPase activator activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1267024

ELMO1
Engulfment and cell motility protein 1

6

20

Small-scale

0.942

High

924868

GRB2
Growth factor receptor-bound protein 2

5

20

High-throughput

0.916

High

802731

CRK
Adapter molecule crk

5

19

Small-scale

0.915

High

1157201

ANR54
Ankyrin repeat domain-containing protein 54

4

6

High-throughput

0.892

High

1295265

ELMO2
Engulfment and cell motility protein 2

4

20

High-throughput

0.892

High

1050494

DOCK1
Dedicator of cytokinesis protein 1

3

13

High-throughput

0.852

High

802906

CRKL
Crk-like protein

2

18

High-throughput

0.811

High

984833

RN5A
2-5A-dependent ribonuclease

2

4

High-throughput

0.811

High

1123328

PKHG4
Puratrophin-1

2

2

High-throughput

0.811

High

1230461

AHI1
Jouberin

2

6

High-throughput

0.811

High

1285559

ELMO3
Engulfment and cell motility protein 3

2

20

High-throughput

0.811

High

1318238

KPCD2
Serine/threonine-protein kinase D2

2

2

High-throughput

0.811

High

545622

RAC2
Ras-related C3 botulinum toxin substrate 2

1

20

High-throughput

0.691

High

1267438

P55G
Phosphatidylinositol 3-kinase regulatory subunit gamma

1

14

High-throughput

0.691

High

205991

TGON2
Trans-Golgi network integral membrane protein 2

2

6

High-throughput

0.628

High

270723

MYCB2
E3 ubiquitin-protein ligase MYCBP2

2

5

High-throughput

0.628

High

301447

UBP19
Ubiquitin carboxyl-terminal hydrolase 19

2

3

High-throughput

0.628

High

787393

PK3CB
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform

2

1

High-throughput

0.628

High

1037399

TBB3
Tubulin beta-3 chain

2

1

High-throughput

0.628

High

1162012

SPSB3
SPRY domain-containing SOCS box protein 3

2

13

High-throughput

0.628

High

1162060

TRI65
E3 ubiquitin-protein ligase TRIM65

2

1

High-throughput

0.628

High

1162306

WDR59
GATOR2 complex protein WDR59

2

3

High-throughput

0.628

High

1245309

PJA1
E3 ubiquitin-protein ligase Praja-1

2

1

High-throughput

0.628

High

1284736

TTC28
Tetratricopeptide repeat protein 28

2

2

High-throughput

0.628

High

1291062

DDX11
ATP-dependent DNA helicase DDX11

2

1

High-throughput

0.628

High

1314979

FANCJ
Fanconi anemia group J protein

2

1

High-throughput

0.628

High

1330826

TBB1
Tubulin beta-1 chain

2

1

High-throughput

0.628

High

1332530

BCAS3
BCAS3 microtubule associated cell migration factor

2

1

High-throughput

0.628

High

1332968

ZHX2
Zinc fingers and homeoboxes protein 2

2

1

High-throughput

0.628

High

1015791

KIF1A
Kinesin-like protein KIF1A

1

2

High-throughput

0.618

High

1220662

MIRO2
Mitochondrial Rho GTPase 2

1

20

High-throughput

0.618

High

349648

RASH
GTPase HRas

1

11

High-throughput

0.618

High

350557

RASK
GTPase KRas

1

15

High-throughput

0.618

High

925620

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.618

High

951344

RHOG
Rho-related GTP-binding protein RhoG

1

20

High-throughput

0.618

High

147359

DPYL4
Dihydropyrimidinase-related protein 4

2

0

High-throughput

0.602

High

843475

AT1A2
Sodium/potassium-transporting ATPase subunit alpha-2

2

0

High-throughput

0.602

High

1056557

BLTP2
Bridge-like lipid transfer protein family member 2

2

0

High-throughput

0.602

High

1065429

RB3GP
Rab3 GTPase-activating protein catalytic subunit

2

0

High-throughput

0.602

High

1242010

SMG8
Nonsense-mediated mRNA decay factor SMG8

2

0

High-throughput

0.602

High

1263672

MADD
MAP kinase-activating death domain protein

2

0

High-throughput

0.602

High

1290007

MOCOS
Molybdenum cofactor sulfurase

2

0

High-throughput

0.602

High

1305770

METH
Methionine synthase

2

0

High-throughput

0.602

High

1332962

GPN2
GPN-loop GTPase 2

2

0

High-throughput

0.602

High

1332963

MKS1
Tectonic-like complex member MKS1

2

0

High-throughput

0.602

High

1286033

ATG2B
Autophagy-related protein 2 homolog B

2

1

High-throughput

0.574

High

324039

BAG2
BAG family molecular chaperone regulator 2

1

1

High-throughput

0.536

High

713144

SDC2
Syndecan-2

1

1

High-throughput

0.536

High

713459

GLYC
Serine hydroxymethyltransferase, cytosolic

1

1

High-throughput

0.536

High

726414

BASI
Basigin

1

2

High-throughput

0.536

High

851683

NEK4
Serine/threonine-protein kinase Nek4

1

3

High-throughput

0.536

High

984285

NMDZ1
Glutamate receptor ionotropic, NMDA 1

1

2

High-throughput

0.536

High

1114238

TBB8
Tubulin beta-8 chain

1

1

High-throughput

0.536

High

1283458

SPSB4
SPRY domain-containing SOCS box protein 4

1

13

High-throughput

0.536

High

1284810

EFMT3
EEF1A lysine methyltransferase 3

1

3

High-throughput

0.536

High

1303752

CDC5L
Cell division cycle 5-like protein

1

1

High-throughput

0.536

High

1305208

SPSB2
SPRY domain-containing SOCS box protein 2

1

10

High-throughput

0.536

High

1332964

HDAC6
Histone deacetylase 6

1

3

High-throughput

0.536

High

868743

ATX1
Ataxin-1

1

0

High-throughput

0.518

High

136068

ACACB
Acetyl-CoA carboxylase 2

1

0

High-throughput

0.513

High

172225

GP182
G-protein coupled receptor 182

1

0

High-throughput

0.513

High

504770

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.513

High

933622

TBA4A
Tubulin alpha-4A chain

1

0

High-throughput

0.513

High

1074414

STIL
SCL-interrupting locus protein

1

0

High-throughput

0.513

High

1083602

SGCA
Alpha-sarcoglycan

1

0

High-throughput

0.513

High

1153054

P4R3A
Serine/threonine-protein phosphatase 4 regulatory subunit 3A

1

0

High-throughput

0.513

High

1243822

WDR19
WD repeat-containing protein 19

1

0

High-throughput

0.513

High

1291118

CDCA5
Sororin

1

0

High-throughput

0.513

High

1299244

OPALI
Opalin

1

0

High-throughput

0.513

High

1138589

LRCH2
Leucine-rich repeat and calponin homology domain-containing protein 2

1

12

High-throughput

0.489

High

1192818

VP13B
Intermembrane lipid transfer protein VPS13B

1

1

High-throughput

0.489

High

1308652

MICU1
Calcium uptake protein 1, mitochondrial

1

2

High-throughput

0.489

High

1332966

VSIG4
V-set and immunoglobulin domain-containing protein 4

1

1

High-throughput

0.489

High

396805

S10A8
Protein S100-A8

1

4

High-throughput

0.479

High

416514

S10A9
Protein S100-A9

1

5

High-throughput

0.479

High

881560

ARL4C
ADP-ribosylation factor-like protein 4C

1

3

High-throughput

0.479

High

1025217

AAPK1
5'-AMP-activated protein kinase catalytic subunit alpha-1

1

1

High-throughput

0.479

High

1042549

CUL3
Cullin-3

1

5

High-throughput

0.479

High

1137569

RIF1
Telomere-associated protein RIF1

1

2

High-throughput

0.479

High

1140768

RN123
E3 ubiquitin-protein ligase RNF123

1

2

High-throughput

0.479

High

1171734

TRI67
Tripartite motif-containing protein 67

1

9

High-throughput

0.479

High

1232699

FBXW8
F-box/WD repeat-containing protein 8

1

5

High-throughput

0.479

High

1332965

INTU
Protein inturned

1

0

High-throughput

0.458

High

551839

DESP
Desmoplakin

1

2

High-throughput

0.445

High

573481

TCPA
T-complex protein 1 subunit alpha

1

3

High-throughput

0.445

High

672304

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

2

High-throughput

0.445

High

672476

2AAB
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform

1

2

High-throughput

0.445

High

771048

TCPZ
T-complex protein 1 subunit zeta

1

3

High-throughput

0.445

High

821412

TCPE
T-complex protein 1 subunit epsilon

1

5

High-throughput

0.445

High

826890

TCPG
T-complex protein 1 subunit gamma

1

4

High-throughput

0.445

High

843054

TCPQ
T-complex protein 1 subunit theta

1

6

High-throughput

0.445

High

843388

TCPD
T-complex protein 1 subunit delta

1

4

High-throughput

0.445

High

931000

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

1

2

High-throughput

0.445

High

943489

TCPB
T-complex protein 1 subunit beta

1

4

High-throughput

0.445

High

1306686

TCPH
T-complex protein 1 subunit eta

1

4

High-throughput

0.445

High

309073

KI20A
Kinesin-like protein KIF20A

1

6

High-throughput

0.437

High

841884

CDK9
Cyclin-dependent kinase 9

1

1

High-throughput

0.437

High

1166871

LRC31
Leucine-rich repeat-containing protein 31

1

4

High-throughput

0.437

High

1303107

YMEL1
ATP-dependent zinc metalloprotease YME1L1

1

1

High-throughput

0.437

High

1332967

TRRAP
Transformation/transcription domain-associated protein

1

1

High-throughput

0.437

High

1315472

CDCA4
Cell division cycle-associated protein 4

1

0

High-throughput

0.426

High

1132341

SZT2
KICSTOR complex protein SZT2

2

0

High-throughput

0.328

High

1268560

K0232
Uncharacterized protein KIAA0232

2

0

High-throughput

0.328

High

1297905

CE034
Uncharacterized protein C5orf34

2

0

High-throughput

0.328

High

1332961

NOL11
Nucleolar protein 11

2

0

High-throughput

0.328

High

1217819

FABD
Malonyl-CoA-acyl carrier protein transacylase, mitochondrial

2

0

High-throughput

0.298

High

1314728

RPAP1
RNA polymerase II-associated protein 1

1

0

High-throughput

0.279

Low

847363

SSRD
Translocon-associated protein subunit delta

1

0

High-throughput

0.249

Low

917929

H4
Histone H4

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024