Protein: ONEC2
One cut domain family member 2 (Hepatocyte nuclear factor 6-beta) (HNF-6-beta) (One cut homeobox 2) (Transcription factor ONECUT-2) (OC-2)

Gene: ONEC2, ONECUT2
Organism: Homo sapiens
Interactions: 11
UniProt ID: O95948

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001889 - liver development

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

351468

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

10

High-throughput

0.536

High

351463

S10A2
Protein S100-A2

1

7

High-throughput

0.489

High

142780

NFIB
Nuclear factor 1 B-type

1

20

High-throughput

0.479

High

351462

NFIC
Nuclear factor 1 C-type

1

20

High-throughput

0.479

High

351464

MECP2
Methyl-CpG-binding protein 2

1

2

High-throughput

0.479

High

351465

H4
Histone H4

1

2

High-throughput

0.479

High

351466

RNF4
E3 ubiquitin-protein ligase RNF4

1

1

High-throughput

0.479

High

351467

NFIA
Nuclear factor 1 A-type

1

20

High-throughput

0.479

High

351469

NFIX
Nuclear factor 1 X-type

1

20

High-throughput

0.479

High

351470

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

2

High-throughput

0.479

High

351471

KDM5B
Lysine-specific demethylase 5B

1

2

Small-scale

0.479

High


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Last updated: 11Aug2025