Protein: PGK
Phosphoglycerate kinase (EC 2.7.2.3)

Gene: PGK, PGK1
Organism: Saccharomyces cerevisiae S288C
Interactions: 220
UniProt ID: P00560

Gene Ontology (top 5):
GO:0004618 - phosphoglycerate kinase activity
GO:0005516 - calmodulin binding
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

340562

PGK
Phosphoglycerate kinase

2

3

Small-scale

0.768

High

340568

HSP82
ATP-dependent molecular chaperone HSP82

4

3

High-throughput

0.672

High

340701

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

3

2

High-throughput

0.640

High

340602

HSC82
ATP-dependent molecular chaperone HSC82

3

3

High-throughput

0.633

High

340593

HSP71
Heat shock protein SSA1

3

1

Small-scale

0.624

High

340595

SSB1
Ribosome-associated molecular chaperone SSB1

3

1

Small-scale

0.624

High

340618

RFA1
Replication factor A protein 1

2

1

High-throughput

0.621

High

340598

ALF
Fructose-bisphosphate aldolase

2

1

Small-scale

0.588

High

340621

SIS1
Protein SIS1

2

0

High-throughput

0.576

High

340683

SPF1
Endoplasmic reticulum transmembrane helix translocase

2

0

High-throughput

0.563

High

340697

LST8
Target of rapamycin complex subunit LST8

2

0

High-throughput

0.563

High

340674

RPN10
26S proteasome regulatory subunit RPN10

2

0

Small-scale

0.559

High

340686

SSB2
Ribosome-associated molecular chaperone SSB2

2

1

High-throughput

0.552

High

340639

ZUO1
Zuotin

2

0

Small-scale

0.547

High

340589

NFT1
ABC transporter NFT1

1

2

High-throughput

0.541

High

340680

YCFI
Metal resistance protein YCF1

1

1

High-throughput

0.541

High

340698

COPB2
Coatomer subunit beta'

2

1

High-throughput

0.537

High

340723

COPA
Coatomer subunit alpha

2

1

High-throughput

0.537

High

340691

MET18
DNA repair/transcription protein MET18/MMS19

1

1

High-throughput

0.536

High

340725

BRE5
UBP3-associated protein BRE5

1

1

High-throughput

0.536

High

340733

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

1

High-throughput

0.536

High

340739

GCN5
Histone acetyltransferase GCN5

1

2

High-throughput

0.536

High

340742

TCB3
Tricalbin-3

1

1

High-throughput

0.536

High

340653

PXA2
Peroxisomal long-chain fatty acid import protein 1

1

0

High-throughput

0.518

High

340700

BUD27
Bud site selection protein 27

1

0

Small-scale

0.518

High

340584

LTE1
Guanine nucleotide exchange factor LTE1

1

0

High-throughput

0.513

High

340585

CHS1
Chitin synthase 1

1

0

High-throughput

0.513

High

340642

PP12
Serine/threonine-protein phosphatase PP1-2

1

0

High-throughput

0.513

High

340695

MAD2
Mitotic spindle checkpoint component MAD2

1

0

High-throughput

0.513

High

340743

ACL4
Assembly chaperone of RPL4

1

0

High-throughput

0.513

High

340751

ASR1
Alcohol-sensitive RING finger protein 1

1

0

High-throughput

0.513

High

340591

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

6

High-throughput

0.501

High

340685

SHO1
High osmolarity signaling protein SHO1

1

0

Small-scale

0.493

High

340612

NUP1
Nucleoporin NUP1

1

1

High-throughput

0.489

High

340590

YK104
Putative uncharacterized protein YKR104W

1

1

High-throughput

0.481

High

340664

RCK1
Serine/threonine-protein kinase RCK1

1

0

High-throughput

0.480

High

334387

G3P2
Glyceraldehyde-3-phosphate dehydrogenase 2

1

4

High-throughput

0.479

High

334561

G3P3
Glyceraldehyde-3-phosphate dehydrogenase 3

1

4

High-throughput

0.479

High

334848

G3P1
Glyceraldehyde-3-phosphate dehydrogenase 1

1

4

High-throughput

0.479

High

336640

SODC
Superoxide dismutase [Cu-Zn]

1

1

High-throughput

0.479

High

339302

CDK1
Cyclin-dependent kinase 1

1

1

High-throughput

0.479

High

340563

ENO1
Enolase 1

1

3

High-throughput

0.479

High

340564

ENO2
Enolase 2

1

3

High-throughput

0.479

High

340566

PMG1
Phosphoglycerate mutase 1

1

3

High-throughput

0.479

High

340567

RS17A
Small ribosomal subunit protein eS17A

1

1

High-throughput

0.479

High

340570

HXKA
Hexokinase-1

1

1

High-throughput

0.479

High

340571

HXKB
Hexokinase-2

1

1

High-throughput

0.479

High

340572

METE
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase

1

1

High-throughput

0.479

High

340586

SYIC
Isoleucine--tRNA ligase, cytoplasmic

1

1

High-throughput

0.479

High

340592

RS6A
Small ribosomal subunit protein eS6A

1

1

High-throughput

0.479

High

340599

CYPH
Peptidyl-prolyl cis-trans isomerase

1

1

High-throughput

0.479

High

340604

STI1
Heat shock protein STI1

1

2

High-throughput

0.479

High

340619

TKT1
Transketolase 1

1

1

High-throughput

0.479

High

340632

MCM4
DNA replication licensing factor MCM4

1

3

High-throughput

0.479

High

340659

MCM7
DNA replication licensing factor MCM7

1

2

High-throughput

0.479

High

340666

RS20
Small ribosomal subunit protein uS10

1

1

High-throughput

0.479

High

340690

MLP2
Protein MLP2

1

1

High-throughput

0.479

High

340717

MCM6
DNA replication licensing factor MCM6

1

3

High-throughput

0.479

High

340726

GIS2
Zinc finger protein GIS2

1

1

High-throughput

0.479

High

340731

ACT
Actin

1

2

Small-scale

0.479

High

340732

NUM1
Nuclear migration protein NUM1

1

2

High-throughput

0.479

High

340738

TOM1
E3 ubiquitin-protein ligase TOM1

1

2

High-throughput

0.479

High

340740

STE20
Serine/threonine-protein kinase STE20

1

1

Small-scale

0.479

High

340745

RUVB1
RuvB-like protein 1

1

1

High-throughput

0.479

High

340747

EFM7
Protein N-terminal and lysine N-methyltransferase EFM7

1

1

High-throughput

0.479

High

340768

RUVB2
RuvB-like protein 2

1

1

High-throughput

0.479

High

340769

SMC6
Structural maintenance of chromosomes protein 6

1

1

High-throughput

0.479

High

340713

SC6B1
Protein transport protein SBH1

1

0

Small-scale

0.460

High

340727

RHO5
GTP-binding protein RHO5

1

0

Small-scale

0.460

High

141012

RS9A
Small ribosomal subunit protein uS4A

1

0

High-throughput

0.458

High

333399

QCR7
Cytochrome b-c1 complex subunit 7, mitochondrial

1

0

High-throughput

0.458

High

335916

COX2
Cytochrome c oxidase subunit 2

1

0

High-throughput

0.458

High

336168

CCPR
Cytochrome c peroxidase, mitochondrial

1

0

Small-scale

0.458

High

339938

KPYK1
Pyruvate kinase 1

1

0

High-throughput

0.458

High

340565

TPIS
Triosephosphate isomerase

1

0

High-throughput

0.458

High

340569

RL25
Large ribosomal subunit protein uL23

1

0

High-throughput

0.458

High

340573

RL26A
Large ribosomal subunit protein uL24A

1

0

High-throughput

0.458

High

340574

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

340575

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.458

High

340576

PDC1
Pyruvate decarboxylase isozyme 1

1

0

High-throughput

0.458

High

340577

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.458

High

340578

KAD2
Adenylate kinase

1

0

High-throughput

0.458

High

340580

DHE4
NADP-specific glutamate dehydrogenase 1

1

0

High-throughput

0.458

High

340581

KAPR
cAMP-dependent protein kinase regulatory subunit

1

0

Small-scale

0.458

High

340582

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.458

High

340583

SYSC
Serine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.458

High

340587

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.458

High

340588

RL31A
Large ribosomal subunit protein eL31A

1

0

High-throughput

0.458

High

340596

G6PI
Glucose-6-phosphate isomerase

1

0

High-throughput

0.458

High

340597

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.458

High

340601

TAL1
Transaldolase

1

0

High-throughput

0.458

High

340605

THRC
Threonine synthase

1

0

High-throughput

0.458

High

340609

PGTB1
Geranylgeranyl transferase type-1 subunit beta

1

0

High-throughput

0.458

High

340611

IRA2
Inhibitory regulator protein IRA2

1

0

Small-scale

0.458

High

340614

OSM1
Fumarate reductase 2

1

0

High-throughput

0.458

High

340615

CBP3
Protein CBP3, mitochondrial

1

0

High-throughput

0.458

High

340616

XRN1
5'-3' exoribonuclease 1

1

0

High-throughput

0.458

High

340620

AATC
Aspartate aminotransferase, cytoplasmic

1

0

High-throughput

0.458

High

340622

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.458

High

340623

GID7
Glucose-induced degradation protein 7

1

0

High-throughput

0.458

High

340624

HSP30
30 kDa heat shock protein

1

0

High-throughput

0.458

High

340625

SPB4
ATP-dependent rRNA helicase SPB4

1

0

High-throughput

0.458

High

340627

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.458

High

340629

HIBCH
Small ribosomal subunit protein mS47

1

0

High-throughput

0.458

High

340633

RENT1
ATP-dependent helicase NAM7

1

0

Small-scale

0.458

High

340634

DHOM
Homoserine dehydrogenase

1

0

High-throughput

0.458

High

340635

HS104
Heat shock protein 104

1

0

High-throughput

0.458

High

340636

P5CR
Pyrroline-5-carboxylate reductase

1

0

High-throughput

0.458

High

340637

RM41
Large ribosomal subunit protein uL23m

1

0

High-throughput

0.458

High

340638

EF1B
Elongation factor 1-beta

1

0

High-throughput

0.458

High

340640

CBS
Cystathionine beta-synthase

1

0

High-throughput

0.458

High

340643

FIMB
Fimbrin

1

0

Small-scale

0.458

High

340645

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.458

High

340646

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

340648

YPT7
Ypt/Rab-type GTPase YPT7

1

0

Small-scale

0.458

High

340649

PRS6A
26S proteasome regulatory subunit 6A

1

0

High-throughput

0.458

High

340651

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.458

High

340654

TCTP
Translationally-controlled tumor protein homolog

1

0

High-throughput

0.458

High

340656

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.458

High

340658

RM28
Large ribosomal subunit protein mL40

1

0

High-throughput

0.458

High

340660

GID4
Vacuolar import and degradation protein 24

1

0

High-throughput

0.458

High

340661

AIM4
Altered inheritance of mitochondria protein 4

1

0

High-throughput

0.458

High

340665

NCB5R
NADH-cytochrome b5 reductase 1

1

0

High-throughput

0.458

High

340667

6PGD1
6-phosphogluconate dehydrogenase, decarboxylating 1

1

0

High-throughput

0.458

High

340668

ECM29
Proteasome component ECM29

1

0

High-throughput

0.458

High

340669

RPN1
26S proteasome regulatory subunit RPN1

1

0

High-throughput

0.458

High

340670

SSZ1
Ribosome-associated complex subunit SSZ1

1

0

Small-scale

0.458

High

340671

NMD2
Nonsense-mediated mRNA decay protein 2

1

0

Small-scale

0.458

High

340673

LNP
Endoplasmic reticulum junction formation protein lunapark

1

0

High-throughput

0.458

High

340679

TCPZ
T-complex protein 1 subunit zeta

1

0

High-throughput

0.458

High

340681

DHH1
ATP-dependent RNA helicase DHH1

1

0

High-throughput

0.458

High

340682

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.458

High

340687

MMF1
Protein MMF1, mitochondrial

1

0

High-throughput

0.458

High

340692

FIS1
Mitochondrial fission 1 protein

1

0

Small-scale

0.458

High

340696

GPP1
Glycerol-1-phosphate phosphohydrolase 1

1

0

High-throughput

0.458

High

340708

UPF3
Nonsense-mediated mRNA decay protein 3

1

0

Small-scale

0.458

High

340710

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

340715

ERG25
C-4 methylsterol oxidase ERG25

1

0

High-throughput

0.458

High

340716

VID30
Vacuolar import and degradation protein 30

1

0

High-throughput

0.458

High

340718

YGK8
Uncharacterized protein YGL108C

1

0

High-throughput

0.458

High

340719

GET1
Golgi to ER traffic protein 1

1

0

High-throughput

0.458

High

340720

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

High-throughput

0.458

High

340729

SAM50
Sorting assembly machinery 50 kDa subunit

1

0

High-throughput

0.458

High

340734

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

340737

COFI
Cofilin

1

0

High-throughput

0.458

High

340741

OYE2
NADPH dehydrogenase 2

1

0

High-throughput

0.458

High

340744

GIS1
Transcriptional activator/repressor GIS1

1

0

High-throughput

0.458

High

340746

SEG1
Eisosome protein SEG1

1

0

High-throughput

0.458

High

340748

PUR8
Adenylosuccinate lyase

1

0

High-throughput

0.458

High

340754

ZEO1
Protein ZEO1

1

0

High-throughput

0.458

High

340757

SGO1
Shugoshin

1

0

High-throughput

0.458

High

340758

TCO89
Target of rapamycin complex 1 subunit TCO89

1

0

High-throughput

0.458

High

340760

YIG1
Protein YIG1

1

0

High-throughput

0.458

High

340765

PST1
Cell wall mannoprotein PST1

1

0

High-throughput

0.458

High

340579

ADR1
Regulatory protein ADR1

1

1

High-throughput

0.445

High

340594

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

340600

SEC63
Protein translocation protein SEC63

1

1

High-throughput

0.445

High

340626

BUB2
Mitotic check point protein BUB2

1

1

High-throughput

0.445

High

340641

HSP7F
Heat shock protein homolog SSE1

1

3

High-throughput

0.445

High

340644

GLRX4
Monothiol glutaredoxin-4

1

2

High-throughput

0.445

High

340662

CLPX
ATP-dependent clpX-like chaperone, mitochondrial

1

3

High-throughput

0.445

High

340676

TCPB
T-complex protein 1 subunit beta

1

1

High-throughput

0.445

High

340678

TCPD
T-complex protein 1 subunit delta

1

1

High-throughput

0.445

High

340684

HSP7E
Heat shock protein SSC3, mitochondrial

1

2

High-throughput

0.445

High

340756

GYP1
GTPase-activating protein GYP1

1

1

High-throughput

0.445

High

340736

ULP1
Ubiquitin-like-specific protease 1

1

1

High-throughput

0.439

High

340613

PUR6
Phosphoribosylaminoimidazole carboxylase

1

0

High-throughput

0.438

High

340608

PDI
Protein disulfide-isomerase

1

2

High-throughput

0.437

High

340630

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

340631

TF3B
Transcription factor IIIB 70 kDa subunit

1

1

High-throughput

0.437

High

340694

RLP7
Ribosome biogenesis protein RLP7

1

1

High-throughput

0.437

High

340735

MLP1
Protein MLP1

1

1

High-throughput

0.437

High

340752

BRE1
E3 ubiquitin-protein ligase BRE1

1

1

Small-scale

0.437

High

340759

AP3D
AP-3 complex subunit delta

1

1

High-throughput

0.437

High

340764

SMT3
Ubiquitin-like protein SMT3

1

2

High-throughput

0.437

High

340606

BIP
Endoplasmic reticulum chaperone BiP

1

0

High-throughput

0.426

High

340610

DDR48
Stress protein DDR48

1

0

High-throughput

0.426

High

340675

TVP23
Golgi apparatus membrane protein TVP23

1

0

High-throughput

0.426

High

340677

TCPG
T-complex protein 1 subunit gamma

1

0

High-throughput

0.426

High

340689

ATM1
Iron-sulfur clusters transporter ATM1, mitochondrial

1

0

High-throughput

0.426

High

340704

JJJ2
J protein JJJ2

1

0

High-throughput

0.426

High

340705

TCPQ
T-complex protein 1 subunit theta

1

0

High-throughput

0.426

High

340712

CWC23
Pre-mRNA-splicing factor CWC23

1

0

High-throughput

0.426

High

340728

APJ1
J domain-containing protein APJ1

1

0

High-throughput

0.426

High

340763

NCE2
Non-classical export protein 2

1

0

High-throughput

0.426

High

340770

RRP12
Ribosomal RNA-processing protein 12

1

0

High-throughput

0.426

High

340755

MED7
Mediator of RNA polymerase II transcription subunit 7

2

0

High-throughput

0.307

High

340766

RPN6
26S proteasome regulatory subunit RPN6

2

0

High-throughput

0.307

High

340607

SPO12
Sporulation-specific protein 12

1

0

High-throughput

0.279

Low

340657

RPF2
Ribosome biogenesis protein RPF2

1

0

High-throughput

0.279

Low

340714

SCS3
Acyl-coenzyme A diphosphatase SCS3

1

0

Small-scale

0.251

Low

340603

SEC11
Signal peptidase complex catalytic subunit SEC11

1

0

High-throughput

0.249

Low

340617

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

0

High-throughput

0.249

Low

340628

PEX3
Peroxisomal biogenesis factor 3

1

0

High-throughput

0.249

Low

340647

SC61A
Protein transport protein SEC61

1

0

High-throughput

0.249

Low

340650

IXR1
Intrastrand cross-link recognition protein

1

0

Small-scale

0.249

Low

340652

PMT1
Dolichyl-phosphate-mannose--protein mannosyltransferase 1

1

0

High-throughput

0.249

Low

340663

YB8A
Putative uncharacterized protein YBR285W

1

0

Small-scale

0.249

Low

340672

GPI16
GPI transamidase component GPI16

1

0

High-throughput

0.249

Low

340693

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.249

Low

340703

PHO86
Inorganic phosphate transporter PHO86

1

0

High-throughput

0.249

Low

340706

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.249

Low

340707

EMC2
ER membrane protein complex subunit 2

1

0

High-throughput

0.249

Low

340711

VATG
V-type proton ATPase subunit G

1

0

High-throughput

0.249

Low

340722

RRN9
RNA polymerase I-specific transcription initiation factor RRN9

1

0

High-throughput

0.249

Low

340730

ASI3
Probable ERAD-associated E3 ubiquitin-protein ligase ASI1

1

0

High-throughput

0.249

Low

340749

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.249

Low

340750

URN1
Pre-mRNA-splicing factor URN1

1

0

High-throughput

0.249

Low

340761

HFI1
Transcriptional coactivator HFI1/ADA1

1

0

Small-scale

0.249

Low

340762

SPC3
Signal peptidase complex subunit 3

1

0

High-throughput

0.249

Low

340655

YET1
Endoplasmic reticulum transmembrane protein 1

1

0

High-throughput

0.232

Low

340688

JEM1
DnaJ-like chaperone JEM1

1

0

High-throughput

0.232

Low

340699

EMP47
Protein EMP47

1

0

High-throughput

0.232

Low

340702

ERJ5
ER-localized J domain-containing protein 5

1

0

High-throughput

0.232

Low

340709

SEC16
COPII coat assembly protein SEC16

1

0

High-throughput

0.232

Low

340721

SCW4
Probable family 17 glucosidase SCW4

1

0

High-throughput

0.232

Low

340724

ALG12
Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase

1

0

High-throughput

0.232

Low

340753

RSC58
Chromatin structure-remodeling complex protein RSC58

1

0

High-throughput

0.232

Low

340767

PEX11
Peroxisomal membrane protein PMP27

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024