Protein: IPYR
Inorganic pyrophosphatase (EC 3.6.1.1) (Pyrophosphate phospho-hydrolase) (PPase)

Gene: IPYR, IPP1
Organism: Saccharomyces cerevisiae S288C
Interactions: 113
UniProt ID: P00817

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0004427 - inorganic diphosphate phosphatase activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006796 - phosphate-containing compound metabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

341776

IPYR2
Inorganic pyrophosphatase, mitochondrial

3

4

High-throughput

0.830

High

341739

IPYR
Inorganic pyrophosphatase

2

4

Small-scale

0.757

High

341820

ROM2
RHO1 GDP-GTP exchange protein 2

4

2

High-throughput

0.694

High

341845

RGL1
RHO1 GEF localizing protein 1

4

0

High-throughput

0.664

High

341740

HSP82
ATP-dependent molecular chaperone HSP82

3

1

High-throughput

0.633

High

341829

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

2

1

Small-scale

0.611

High

341837

TUS1
Rho1 guanine nucleotide exchange factor TUS1

3

2

High-throughput

0.604

High

341741

EF1A
Elongation factor 1-alpha

2

1

High-throughput

0.588

High

341815

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

1

High-throughput

0.584

High

341758

SSB1
Ribosome-associated molecular chaperone SSB1

2

2

High-throughput

0.552

High

341848

CMR1
DNA damage-binding protein CMR1

1

0

High-throughput

0.529

High

341767

DBP4
ATP-dependent RNA helicase HCA4

1

1

High-throughput

0.515

High

341818

IMDH4
Inosine-5'-monophosphate dehydrogenase 4

1

2

High-throughput

0.515

High

341630

ARGI
Arginase

1

0

High-throughput

0.513

High

341748

HAP2
Transcriptional activator HAP2

1

0

High-throughput

0.513

High

341769

RAD53
Serine/threonine-protein kinase RAD53

1

0

High-throughput

0.513

High

341779

HRR25
Casein kinase I homolog HRR25

1

0

High-throughput

0.513

High

341789

SLD2
DNA replication regulator SLD2

1

0

High-throughput

0.513

High

341825

BRE5
UBP3-associated protein BRE5

1

0

High-throughput

0.513

High

341828

SLT2
Mitogen-activated protein kinase SLT2/MPK1

1

0

High-throughput

0.513

High

341802

RSP5
E3 ubiquitin-protein ligase RSP5

1

1

High-throughput

0.501

High

341766

FKBP
FK506-binding protein 1

1

1

High-throughput

0.500

High

341782

FIMB
Fimbrin

1

1

High-throughput

0.500

High

341826

RHO5
GTP-binding protein RHO5

1

7

High-throughput

0.500

High

341791

SHB17
Sedoheptulose 1,7-bisphosphatase

1

0

High-throughput

0.493

High

341811

DPH1
2-(3-amino-3-carboxypropyl)histidine synthase subunit 1

1

0

High-throughput

0.493

High

341813

SA185
SIT4-associating protein SAP185

1

0

High-throughput

0.493

High

341847

GST2
Glutathione S-transferase 2

1

0

High-throughput

0.493

High

341774

RL16A
Large ribosomal subunit protein uL13A

1

2

High-throughput

0.489

High

341804

RL13B
Large ribosomal subunit protein eL13B

1

1

High-throughput

0.489

High

341812

ULP2
Ubiquitin-like-specific protease 2

1

1

High-throughput

0.481

High

341831

ULP1
Ubiquitin-like-specific protease 1

1

1

High-throughput

0.481

High

341771

ESS1
Peptidyl-prolyl cis-trans isomerase ESS1

1

0

High-throughput

0.480

High

341838

URN1
Pre-mRNA-splicing factor URN1

1

0

High-throughput

0.480

High

341765

PRP6
Pre-mRNA-splicing factor 6

1

0

High-throughput

0.479

High

341747

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.479

High

341752

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

4

Small-scale

0.479

High

341762

HSC82
ATP-dependent molecular chaperone HSC82

1

1

High-throughput

0.479

High

341770

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

1

High-throughput

0.479

High

341772

SIS1
Protein SIS1

1

1

High-throughput

0.479

High

341773

RS2
Small ribosomal subunit protein uS5

1

1

High-throughput

0.479

High

341777

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.479

High

341778

TF3B
Transcription factor IIIB 70 kDa subunit

1

1

High-throughput

0.479

High

341780

BMH1
Protein BMH1

1

1

High-throughput

0.479

High

341795

RS20
Small ribosomal subunit protein uS10

1

1

High-throughput

0.479

High

341822

ROM1
RHO1 GDP-GTP exchange protein 1

1

4

High-throughput

0.479

High

341833

TOM1
E3 ubiquitin-protein ligase TOM1

1

1

High-throughput

0.479

High

341834

GIS1
Transcriptional activator/repressor GIS1

1

2

High-throughput

0.479

High

141013

RS9A
Small ribosomal subunit protein uS4A

1

0

High-throughput

0.458

High

341742

CARB
Carbamoyl phosphate synthase arginine-specific large chain

1

0

High-throughput

0.458

High

341743

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

0

High-throughput

0.458

High

341745

HXKA
Hexokinase-1

1

0

Small-scale

0.458

High

341768

XRN1
5'-3' exoribonuclease 1

1

0

High-throughput

0.458

High

341788

MSN2
Zinc finger protein MSN2

1

0

High-throughput

0.458

High

341790

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.458

High

341793

UBP13
Ubiquitin carboxyl-terminal hydrolase 13

1

0

High-throughput

0.458

High

341796

RPN1
26S proteasome regulatory subunit RPN1

1

0

High-throughput

0.458

High

341797

RPN10
26S proteasome regulatory subunit RPN10

1

0

High-throughput

0.458

High

341800

DHH1
ATP-dependent RNA helicase DHH1

1

0

High-throughput

0.458

High

341817

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.458

High

341824

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

High-throughput

0.458

High

341830

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

341835

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

341836

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.458

High

341843

SGO1
Shugoshin

1

0

High-throughput

0.458

High

341755

HSP71
Heat shock protein SSA1

1

3

High-throughput

0.445

High

341756

HSP72
Heat shock protein SSA2

1

3

High-throughput

0.445

High

341763

BIP
Endoplasmic reticulum chaperone BiP

1

1

High-throughput

0.445

High

341781

HSP7F
Heat shock protein homolog SSE1

1

4

High-throughput

0.445

High

341786

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.445

High

341803

SSB2
Ribosome-associated molecular chaperone SSB2

1

2

High-throughput

0.445

High

341819

IMDH3
Inosine-5'-monophosphate dehydrogenase 3

1

2

High-throughput

0.445

High

341840

BRE1
E3 ubiquitin-protein ligase BRE1

1

1

High-throughput

0.445

High

341846

RL7B
Large ribosomal subunit protein uL30B

1

1

High-throughput

0.445

High

341783

RSSA1
Small ribosomal subunit protein uS2A

1

1

High-throughput

0.437

High

341787

RS3A1
Small ribosomal subunit protein eS1A

1

1

High-throughput

0.437

High

341810

MLP2
Protein MLP2

1

1

High-throughput

0.437

High

341844

AP3D
AP-3 complex subunit delta

1

1

High-throughput

0.437

High

341757

RL4A
Large ribosomal subunit protein uL4A

1

0

High-throughput

0.426

High

341759

RL30
Large ribosomal subunit protein eL30

1

0

High-throughput

0.426

High

341760

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.426

High

341807

PSF2
DNA replication complex GINS protein PSF2

1

0

High-throughput

0.426

High

341808

6P21
6-phosphofructo-2-kinase 1

1

0

High-throughput

0.426

High

341816

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.426

High

341832

LGE1
Transcriptional regulatory protein LGE1

1

0

High-throughput

0.426

High

341841

ACK1
Activator of C kinase protein 1

3

0

High-throughput

0.345

High

341749

CALM
Calmodulin

2

0

Small-scale

0.333

High

341823

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

2

0

High-throughput

0.307

High

341794

ATG12
Ubiquitin-like protein ATG12

1

0

High-throughput

0.279

Low

341799

RS14B
Small ribosomal subunit protein uS11B

1

0

High-throughput

0.279

Low

341806

NTA1
Protein N-terminal amidase

1

0

High-throughput

0.279

Low

341805

DOA10
ERAD-associated E3 ubiquitin-protein ligase DOA10

1

0

High-throughput

0.261

Low

341814

BNI1
Protein BNI1

1

0

High-throughput

0.261

Low

341842

AUS1
ATP-dependent permease AUS1

1

0

High-throughput

0.261

Low

341784

SUI1
Eukaryotic translation initiation factor eIF-1

1

0

High-throughput

0.261

Low

341821

SEH1
Nucleoporin SEH1

1

0

High-throughput

0.261

Low

341839

YP097
PX domain-containing protein YPR097W

1

0

Small-scale

0.251

Low

341744

RL25
Large ribosomal subunit protein uL23

1

0

High-throughput

0.249

Low

341746

RL26A
Large ribosomal subunit protein uL24A

1

0

High-throughput

0.249

Low

341750

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.249

Low

341751

RL27A
Large ribosomal subunit protein eL27A

1

0

High-throughput

0.249

Low

341753

RS6A
Small ribosomal subunit protein eS6A

1

0

High-throughput

0.249

Low

341754

RL2A
Large ribosomal subunit protein uL2A

1

0

High-throughput

0.249

Low

341764

TPM1
Tropomyosin-1

1

0

Small-scale

0.249

Low

341775

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.249

Low

341785

YPT7
Ypt/Rab-type GTPase YPT7

1

0

Small-scale

0.249

Low

341792

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

341801

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

341827

SAM50
Sorting assembly machinery 50 kDa subunit

1

0

High-throughput

0.249

Low

341761

RS17B
Small ribosomal subunit protein eS17B

1

0

High-throughput

0.232

Low

341798

TCPZ
T-complex protein 1 subunit zeta

1

0

High-throughput

0.232

Low

341809

YIQ1
Uncharacterized protein YIL161W

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024