Protein: IMB3
Importin subunit beta-3 (Karyopherin subunit beta-3) (Karyopherin-121) (Protein secretion enhancer 1)

Gene: IMB3, PSE1
Organism: Saccharomyces cerevisiae S288C
Interactions: 180
UniProt ID: P32337

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006406 - mRNA export from nucleus
GO:0006606 - protein import into nucleus
GO:0007088 - regulation of mitotic nuclear division

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

687908

GSP1
GTP-binding nuclear protein GSP1/CNR1

9

17

Small-scale

0.971

High

688003

IMB1
Importin subunit beta-1

4

12

Small-scale

0.892

High

687990

IMA1
Importin subunit alpha

2

20

High-throughput

0.802

High

687909

GSP2
GTP-binding nuclear protein GSP2/CNR2

2

17

Small-scale

0.775

High

687994

NUP53
Nucleoporin NUP53

9

4

Small-scale

0.754

High

687988

ULP1
Ubiquitin-like-specific protease 1

7

6

Small-scale

0.751

High

688014

YRA1
RNA annealing protein YRA1

5

4

Small-scale

0.720

High

356316

H4
Histone H4

5

5

Small-scale

0.716

High

687995

ARX1
Probable metalloprotease ARX1

5

1

Small-scale

0.706

High

687986

NU100
Nucleoporin NUP100/NSP100

5

20

Small-scale

0.704

High

595002

NUP1
Nucleoporin NUP1

4

20

Small-scale

0.694

High

687967

NUP57
Nucleoporin NUP57

4

20

Small-scale

0.685

High

687987

NU116
Nucleoporin NUP116/NSP116

4

20

Small-scale

0.680

High

687981

H3
Histone H3

3

13

Small-scale

0.674

High

687975

SLX9
Ribosome biogenesis protein SLX9

4

0

High-throughput

0.664

High

541851

NSP1
Nucleoporin NSP1

3

20

Small-scale

0.656

High

392078

H2A1
Histone H2A.1

3

7

Small-scale

0.651

High

687969

NU145
Nucleoporin NUP145

3

20

Small-scale

0.651

High

425320

PHO4
Phosphate system positive regulatory protein PHO4

3

0

Small-scale

0.650

High

687942

ECM1
Shuttling pre-60S factor ECM1

3

1

Small-scale

0.643

High

688019

RRP12
Ribosomal RNA-processing protein 12

3

0

Small-scale

0.634

High

587827

AP1
AP-1-like transcription factor YAP1

2

2

Small-scale

0.629

High

533933

INO4
Protein INO4

3

0

High-throughput

0.629

High

493427

HSP72
Heat shock protein SSA2

3

12

Small-scale

0.624

High

597298

PSA1
Proteasome subunit alpha type-1

2

1

High-throughput

0.621

High

687912

PRS6A
26S proteasome regulatory subunit 6A

2

1

High-throughput

0.621

High

565265

SPO12
Sporulation-specific protein 12

2

0

Small-scale

0.618

High

687965

ALB1
Ribosome biogenesis protein ALB1

2

0

Small-scale

0.616

High

687973

DUO1
DASH complex subunit DUO1

3

0

Small-scale

0.616

High

687983

CDC14
Tyrosine-protein phosphatase CDC14

2

15

Small-scale

0.611

High

687937

IPL1
Spindle assembly checkpoint kinase

2

3

Small-scale

0.611

High

688005

DBP9
ATP-dependent RNA helicase DBP9

3

4

High-throughput

0.609

High

687978

PAP2
Poly(A) RNA polymerase protein 2

2

1

High-throughput

0.601

High

619426

PSA2
Proteasome subunit alpha type-2

2

0

High-throughput

0.595

High

687950

PSA6
Proteasome subunit alpha type-6

2

0

High-throughput

0.595

High

687951

PSA4
Proteasome subunit alpha type-4

2

0

High-throughput

0.595

High

687972

MDS3
Negative regulator of sporulation MDS3

2

0

High-throughput

0.595

High

688000

YM91
Putative methyltransferase YMR310C

2

0

High-throughput

0.595

High

355391

H2B1
Histone H2B.1

2

4

Small-scale

0.595

High

526963

TBP
TATA-box-binding protein

2

1

Small-scale

0.595

High

687985

NUP49
Nucleoporin NUP49/NSP49

2

20

Small-scale

0.595

High

529997

STE12
Protein STE12

2

0

Small-scale

0.592

High

597213

PSA7
Probable proteasome subunit alpha type-7

2

1

High-throughput

0.588

High

687913

PRS6B
26S proteasome regulatory subunit 6B homolog

2

1

High-throughput

0.588

High

687941

BDH2
Probable diacetyl reductase [(R)-acetoin forming] 2

2

3

High-throughput

0.588

High

687919

NIC96
Nucleoporin NIC96

1

3

Small-scale

0.578

High

687976

DAM1
DASH complex subunit DAM1

2

0

Small-scale

0.576

High

406876

RS3
Small ribosomal subunit protein uS3

2

2

High-throughput

0.571

High

540050

GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

2

1

High-throughput

0.567

High

558587

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial

2

1

High-throughput

0.567

High

613045

SPA2
Protein SPA2

2

2

High-throughput

0.567

High

687861

NUD1
Protein NUD1

2

0

High-throughput

0.563

High

510571

SSB1
Ribosome-associated molecular chaperone SSB1

2

11

High-throughput

0.552

High

687926

YRA2
RNA annealing protein YRA2

1

0

Small-scale

0.537

High

687955

LYS12
Homoisocitrate dehydrogenase, mitochondrial

2

6

High-throughput

0.537

High

419316

HAP2
Transcriptional activator HAP2

1

2

High-throughput

0.536

High

424396

PYR1
Multifunctional protein URA2

1

3

High-throughput

0.536

High

454230

TBA1
Tubulin alpha-1 chain

1

3

High-throughput

0.536

High

597119

ACE2
Metallothionein expression activator

1

1

High-throughput

0.515

High

645741

FEN1
Flap endonuclease 1

1

1

High-throughput

0.515

High

687948

GLE2
mRNA export factor GLE2

1

5

High-throughput

0.515

High

687917

DCA13
Protein SOF1

1

5

Small-scale

0.512

High

687943

RV167
Reduced viability upon starvation protein 167

1

2

Small-scale

0.508

High

687970

GCH1
GTP cyclohydrolase 1

1

1

High-throughput

0.508

High

456460

HO
Homothallic switching endonuclease

1

0

Small-scale

0.504

High

481002

RL23B
Large ribosomal subunit protein uL14B

1

1

Small-scale

0.501

High

687906

NUP2
Nucleoporin NUP2

1

20

Small-scale

0.501

High

687928

NU133
Nucleoporin NUP133

1

1

Small-scale

0.501

High

687940

NUP60
Nucleoporin NUP60

1

2

Small-scale

0.501

High

687959

T2FB
Transcription initiation factor IIF subunit beta

1

1

Small-scale

0.501

High

687971

NU188
Nucleoporin NUP188

1

1

Small-scale

0.501

High

688006

TSR2
Pre-rRNA-processing protein TSR2

1

2

Small-scale

0.501

High

688007

ASR1
Alcohol-sensitive RING finger protein 1

1

3

Small-scale

0.501

High

688013

KAD6
Adenylate kinase isoenzyme 6 homolog FAP7

1

2

Small-scale

0.501

High

648299

GYS2
Glycogen [starch] synthase isoform 2

1

0

High-throughput

0.493

High

687947

THO1
Protein THO1

1

0

High-throughput

0.493

High

687977

NOP19
Nucleolar protein 19

1

0

High-throughput

0.493

High

688018

KCS1
Inositol hexakisphosphate kinase 1

1

0

High-throughput

0.493

High

687925

MAOM
NAD-dependent malic enzyme, mitochondrial

1

1

High-throughput

0.489

High

687935

AIM46
Altered inheritance of mitochondria protein 46, mitochondrial

1

1

High-throughput

0.489

High

585865

RDS2
Regulator of drug sensitivity 2

1

0

High-throughput

0.486

High

641123

DAL80
Nitrogen regulatory protein DAL80

1

0

High-throughput

0.486

High

687934

DNPEP
Aspartyl aminopeptidase 4

1

0

High-throughput

0.486

High

687946

ACA1
ATF/CREB activator 1

1

0

High-throughput

0.486

High

687956

MND2
Anaphase-promoting complex subunit MND2

1

0

High-throughput

0.486

High

687999

CSM3
Chromosome segregation in meiosis protein 3

1

0

High-throughput

0.486

High

688010

RDR1
Protein RDR1

1

0

High-throughput

0.486

High

688017

WTM2
Transcriptional modulator WTM2

1

0

High-throughput

0.486

High

535754

ABF1
ARS-binding factor 1

1

0

Small-scale

0.480

High

605214

AFT1
Iron-regulated transcriptional activator AFT1

1

0

Small-scale

0.480

High

141214

RS9A
Small ribosomal subunit protein uS4A

1

3

High-throughput

0.479

High

365959

HSP82
ATP-dependent molecular chaperone HSP82

1

9

High-throughput

0.479

High

407795

RS13
Small ribosomal subunit protein uS15

1

2

High-throughput

0.479

High

543372

HSC82
ATP-dependent molecular chaperone HSC82

1

9

High-throughput

0.479

High

606573

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

2

High-throughput

0.479

High

627796

SIS1
Protein SIS1

1

3

High-throughput

0.479

High

631733

RS2
Small ribosomal subunit protein uS5

1

2

High-throughput

0.479

High

661593

TF2B
Transcription initiation factor IIB

1

4

High-throughput

0.479

High

687903

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

2

High-throughput

0.479

High

687911

SMY2
Protein SMY2

1

3

High-throughput

0.479

High

687921

DEF1
RNA polymerase II degradation factor 1

1

2

High-throughput

0.479

High

687922

RS27A
Small ribosomal subunit protein eS27A

1

2

High-throughput

0.479

High

687924

CENPA
Histone H3-like centromeric protein CSE4

1

13

High-throughput

0.479

High

687931

PLPHP
Pyridoxal phosphate homeostasis protein

1

1

High-throughput

0.479

High

687932

RS20
Small ribosomal subunit protein uS10

1

2

High-throughput

0.479

High

687949

IMB4
Importin subunit beta-4

1

11

High-throughput

0.479

High

687954

NU159
Nucleoporin NUP159

1

20

Small-scale

0.479

High

687957

SAS2
Histone acetyltransferase SAS2

1

3

Small-scale

0.479

High

687962

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

5

High-throughput

0.479

High

687966

RS12
Small ribosomal subunit protein eS12

1

1

High-throughput

0.479

High

687974

CDH1
APC/C activator protein CDH1

1

12

Small-scale

0.479

High

687979

HST2
NAD-dependent protein deacetylase HST2

1

7

High-throughput

0.479

High

687980

UFD2
E4 ubiquitin-protein ligase UFD2

1

1

High-throughput

0.479

High

687984

RS15
Small ribosomal subunit protein uS19

1

1

High-throughput

0.479

High

687997

SXM1
Importin beta SMX1

1

9

High-throughput

0.479

High

688016

RIO1
Serine/threonine-protein kinase RIO1

1

4

High-throughput

0.479

High

343102

THDH
Threonine dehydratase, mitochondrial

1

2

High-throughput

0.464

High

581272

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

3

High-throughput

0.464

High

687920

DHSO1
Sorbitol dehydrogenase 1

1

3

High-throughput

0.464

High

687923

AP1B1
AP-1 complex subunit beta-1

1

1

High-throughput

0.464

High

688008

DHSO2
Sorbitol dehydrogenase 2

1

3

High-throughput

0.464

High

419458

PDE2
3',5'-cyclic-nucleotide phosphodiesterase 2

1

0

High-throughput

0.458

High

519497

PDR1
Transcription factor PDR1

1

0

Small-scale

0.458

High

549595

KCY
Uridylate kinase

1

0

High-throughput

0.458

High

687953

NUP82
Nucleoporin NUP82

1

0

Small-scale

0.458

High

687961

LOC1
60S ribosomal subunit assembly/export protein LOC1

1

0

Small-scale

0.458

High

687998

PUF6
Pumilio homology domain family member 6

1

0

Small-scale

0.458

High

688004

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.458

High

687938

RS14B
Small ribosomal subunit protein uS11B

1

5

Small-scale

0.457

High

687944

RS26A
Small ribosomal subunit protein eS26A

1

4

Small-scale

0.457

High

687945

RS26B
Small ribosomal subunit protein eS26B

1

4

Small-scale

0.457

High

687968

NUP42
Nucleoporin NUP42

1

20

Small-scale

0.457

High

688002

NUP59
Nucleoporin ASM4

1

4

Small-scale

0.457

High

688015

POM33
Pore membrane protein of 33 kDa

1

4

Small-scale

0.457

High

360789

TBB
Tubulin beta chain

1

3

High-throughput

0.445

High

367840

EF1A
Elongation factor 1-alpha

1

3

High-throughput

0.445

High

404522

RL7A
Large ribosomal subunit protein uL30A

1

1

High-throughput

0.445

High

490606

HSP71
Heat shock protein SSA1

1

12

High-throughput

0.445

High

498841

RL4A
Large ribosomal subunit protein uL4A

1

5

High-throughput

0.445

High

555883

VATB
V-type proton ATPase subunit B

1

3

High-throughput

0.445

High

687907

HSP7F
Heat shock protein homolog SSE1

1

14

High-throughput

0.445

High

687914

PRS7
26S proteasome regulatory subunit 7 homolog

1

3

High-throughput

0.445

High

687916

MSN2
Zinc finger protein MSN2

1

2

High-throughput

0.445

High

687958

RL10
Large ribosomal subunit protein uL16

1

1

High-throughput

0.445

High

687960

MPG1
Mannose-1-phosphate guanyltransferase

1

3

High-throughput

0.445

High

687964

PFD1
Prefoldin subunit 1

1

1

High-throughput

0.445

High

687996

RUVB1
RuvB-like protein 1

1

6

High-throughput

0.445

High

357946

RS17A
Small ribosomal subunit protein eS17A

1

1

High-throughput

0.437

High

383010

RL25
Large ribosomal subunit protein uL23

1

3

Small-scale

0.437

High

470925

RS22A
Small ribosomal subunit protein uS8A

1

1

High-throughput

0.437

High

549351

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

2

Small-scale

0.437

High

638672

SPB4
ATP-dependent rRNA helicase SPB4

1

3

High-throughput

0.437

High

687902

NDI1
Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial

1

6

High-throughput

0.437

High

687905

ERG1
Squalene epoxidase ERG1

1

3

High-throughput

0.437

High

687910

RSSA1
Small ribosomal subunit protein uS2A

1

4

High-throughput

0.437

High

687915

PLSC
1-acyl-sn-glycerol-3-phosphate acyltransferase

1

5

High-throughput

0.437

High

687918

GCN1
eIF-2-alpha kinase activator GCN1

1

10

High-throughput

0.437

High

687929

PDX3
Pyridoxamine 5'-phosphate oxidase

1

1

High-throughput

0.437

High

687930

ARA1
D-arabinose dehydrogenase [NAD(P)+] heavy chain

1

1

High-throughput

0.437

High

687939

ELO1
Fatty acid elongase 1

1

4

High-throughput

0.437

High

687952

ELO3
Fatty acid elongase 3

1

4

High-throughput

0.437

High

687982

NUM1
Nuclear migration protein NUM1

1

4

High-throughput

0.437

High

687992

YM59
Uncharacterized protein YMR209C

1

1

High-throughput

0.437

High

688009

RS10A
Small ribosomal subunit protein eS10A

1

1

High-throughput

0.437

High

688011

AP3D
AP-3 complex subunit delta

1

3

High-throughput

0.437

High

688020

SAS5
Something about silencing protein 5

1

1

Small-scale

0.437

High

340066

KPYK1
Pyruvate kinase 1

1

0

High-throughput

0.426

High

687989

CENPP
Inner kinetochore subunit CTF19

1

0

High-throughput

0.426

High

576219

ERD2
ER lumen protein-retaining receptor

1

2

High-throughput

0.407

High

687933

LAG1
Ceramide synthase LAG1

1

5

High-throughput

0.407

High

687904

ODPB
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

2

0

High-throughput

0.324

High

688001

NTE1
Lysophospholipase NTE1

2

0

High-throughput

0.307

High

687936

CH10
10 kDa heat shock protein, mitochondrial

1

0

High-throughput

0.265

Low

687991

AAD16
Putative aryl-alcohol dehydrogenase AAD16

1

0

High-throughput

0.265

Low

688012

TFB4
General transcription and DNA repair factor IIH subunit TFB4

1

0

Small-scale

0.261

Low

479079

RL43B
Large ribosomal subunit protein eL43B

1

0

Small-scale

0.249

Low

645317

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.249

Low

687927

PSG1
PMA1 stabilization in the Golgi protein 1 [Cleaved into: PSG1-N'; PSG1-C']

1

0

High-throughput

0.249

Low

687963

ALG2
Alpha-1,3/1,6-mannosyltransferase ALG2

1

0

High-throughput

0.249

Low

687993

ESC1
Silent chromatin protein ESC1

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024