Protein: NHP2
H/ACA ribonucleoprotein complex subunit NHP2 (H/ACA snoRNP protein NHP2) (High mobility group-like nuclear protein 2)

Gene: NHP2
Organism: Saccharomyces cerevisiae S288C
Interactions: 141
UniProt ID: P32495

Gene Ontology (top 5):
GO:0000454 - snoRNA guided rRNA pseudouridine synthesis
GO:0000470 - maturation of LSU-rRNA
GO:0000493 - box H/ACA snoRNP assembly
GO:0003735 - structural constituent of ribosome
GO:0005730 - nucleolus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

691448

NOP10
H/ACA ribonucleoprotein complex subunit NOP10

4

2

Small-scale

0.894

High

549354

FBRL
rRNA 2'-O-methyltransferase fibrillarin

4

2

Small-scale

0.886

High

691419

ERB1
Ribosome biogenesis protein ERB1

3

7

High-throughput

0.839

High

691424

UTP21
U3 small nucleolar RNA-associated protein 21

3

6

Small-scale

0.830

High

691359

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

12

4

Small-scale

0.759

High

655818

GAR1
H/ACA ribonucleoprotein complex subunit GAR1

8

4

Small-scale

0.751

High

691404

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

8

1

Small-scale

0.748

High

589066

PRP4
U4/U6 small nuclear ribonucleoprotein PRP4

2

10

High-throughput

0.679

High

691393

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

3

1

High-throughput

0.669

High

691395

PESC
Pescadillo homolog

1

2

High-throughput

0.665

High

635100

YCQ6
Uncharacterized protein YCR016W

3

1

High-throughput

0.650

High

691376

NOC2
Nucleolar complex protein 2

3

2

High-throughput

0.643

High

691384

UTP10
U3 small nucleolar RNA-associated protein 10

3

3

High-throughput

0.643

High

691433

NOP6
Nucleolar protein 6

3

0

High-throughput

0.638

High

691420

YM91
Putative methyltransferase YMR310C

4

1

High-throughput

0.623

High

141220

RS9A
Small ribosomal subunit protein uS4A

1

4

High-throughput

0.618

High

407800

RS13
Small ribosomal subunit protein uS15

1

3

High-throughput

0.618

High

408303

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

4

High-throughput

0.618

High

597808

PWP1
Periodic tryptophan protein 1

1

14

High-throughput

0.618

High

691370

GBLP
Small ribosomal subunit protein RACK1

1

12

High-throughput

0.618

High

691371

ENP1
Essential nuclear protein 1

1

3

High-throughput

0.618

High

691389

RS12
Small ribosomal subunit protein eS12

1

2

High-throughput

0.618

High

691437

RS10A
Small ribosomal subunit protein eS10A

1

2

High-throughput

0.618

High

691445

NOP56
Nucleolar protein 56

1

9

High-throughput

0.618

High

691446

NOP58
Nucleolar protein 58

1

9

High-throughput

0.618

High

691362

URB1
Nucleolar pre-ribosomal-associated protein 1

3

0

Small-scale

0.616

High

593510

DBP3
ATP-dependent RNA helicase DBP3

2

4

High-throughput

0.612

High

634527

KRR1
KRR1 small subunit processome component

2

4

High-throughput

0.601

High

691368

RPF2
Ribosome biogenesis protein RPF2

2

4

High-throughput

0.601

High

691397

YG5X
Putative methyltransferase YGR283C

2

1

High-throughput

0.601

High

691443

UTP23
rRNA-processing protein UTP23

2

2

Small-scale

0.595

High

691415

HAS1
ATP-dependent RNA helicase HAS1

2

15

High-throughput

0.588

High

534714

RL30
Large ribosomal subunit protein eL30

1

3

High-throughput

0.575

High

357949

RS17A
Small ribosomal subunit protein eS17A

2

3

High-throughput

0.571

High

604955

XRN1
5'-3' exoribonuclease 1

2

2

High-throughput

0.571

High

691358

RSSA1
Small ribosomal subunit protein uS2A

2

2

High-throughput

0.571

High

691421

RRP5
rRNA biogenesis protein RRP5

2

2

High-throughput

0.571

High

691378

SSB2
Ribosome-associated molecular chaperone SSB2

2

5

High-throughput

0.552

High

624047

DBP2
ATP-dependent RNA helicase DBP2

1

4

High-throughput

0.541

High

691366

EBP2
rRNA-processing protein EBP2

1

3

High-throughput

0.541

High

691396

PXR1
Protein PXR1

1

1

High-throughput

0.541

High

691399

DBP6
ATP-dependent RNA helicase DBP6

1

7

High-throughput

0.541

High

634111

SRO9
RNA-binding protein SRO9

2

5

High-throughput

0.537

High

688712

AAR2
A1 cistron-splicing factor AAR2

2

1

High-throughput

0.537

High

691365

SN114
Pre-mRNA-splicing factor SNU114

2

4

High-throughput

0.537

High

691377

RSMB
Small nuclear ribonucleoprotein-associated protein B

2

3

High-throughput

0.537

High

691444

SNU66
66 kDa U4/U6.U5 small nuclear ribonucleoprotein component

2

2

High-throughput

0.537

High

376686

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

2

2

Small-scale

0.521

High

691386

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

0

High-throughput

0.518

High

691383

KRI1
Protein KRI1

1

1

High-throughput

0.515

High

691416

HMO1
High mobility group protein 1

1

5

High-throughput

0.515

High

675890

XPO1
Exportin-1

1

4

High-throughput

0.489

High

691400

BRE5
UBP3-associated protein BRE5

1

4

High-throughput

0.489

High

691410

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

6

High-throughput

0.489

High

691379

SHQ1
Protein SHQ1

1

0

Small-scale

0.480

High

383016

RL25
Large ribosomal subunit protein uL23

1

4

High-throughput

0.479

High

405500

RL26A
Large ribosomal subunit protein uL24A

1

7

High-throughput

0.479

High

413379

RS14A
Small ribosomal subunit protein uS11A

1

3

High-throughput

0.479

High

425827

RS19A
Small ribosomal subunit protein eS19A

1

2

High-throughput

0.479

High

470931

RS22A
Small ribosomal subunit protein uS8A

1

2

High-throughput

0.479

High

472082

RL31A
Large ribosomal subunit protein eL31A

1

5

High-throughput

0.479

High

479987

RS6A
Small ribosomal subunit protein eS6A

1

3

High-throughput

0.479

High

480550

RS8A
Small ribosomal subunit protein eS8A

1

3

High-throughput

0.479

High

482146

RS18A
Small ribosomal subunit protein uS13A

1

2

High-throughput

0.479

High

520484

RM02
Large ribosomal subunit protein bL27m

1

1

High-throughput

0.479

High

548373

MS116
ATP-dependent RNA helicase MSS116, mitochondrial

1

15

High-throughput

0.479

High

631741

RS2
Small ribosomal subunit protein uS5

1

3

High-throughput

0.479

High

638680

SPB4
ATP-dependent rRNA helicase SPB4

1

11

High-throughput

0.479

High

645323

RS7A
Small ribosomal subunit protein eS7A

1

2

High-throughput

0.479

High

691361

RS3A1
Small ribosomal subunit protein eS1A

1

3

High-throughput

0.479

High

691363

RS27A
Small ribosomal subunit protein eS27A

1

2

High-throughput

0.479

High

691367

DBP7
ATP-dependent RNA helicase DBP7

1

14

Small-scale

0.479

High

691372

RS20
Small ribosomal subunit protein uS10

1

2

High-throughput

0.479

High

691373

SSF1
Ribosome biogenesis protein SSF1

1

4

High-throughput

0.479

High

691381

RLP7
Ribosome biogenesis protein RLP7

1

8

High-throughput

0.479

High

691387

NOP9
Nucleolar protein 9

1

1

Small-scale

0.479

High

691394

EIF2A
Eukaryotic translation initiation factor 2A

1

3

High-throughput

0.479

High

691398

PAP2
Poly(A) RNA polymerase protein 2

1

4

Small-scale

0.479

High

691405

NOP15
Ribosome biogenesis protein 15

1

5

High-throughput

0.479

High

691411

RS15
Small ribosomal subunit protein uS19

1

3

High-throughput

0.479

High

691413

TOM1
E3 ubiquitin-protein ligase TOM1

1

12

High-throughput

0.479

High

691418

DHR1
Probable ATP-dependent RNA helicase DHR1

1

4

High-throughput

0.479

High

691425

MRD1
Multiple RNA-binding domain-containing protein 1

1

4

High-throughput

0.479

High

691430

NOC4
Nucleolar complex protein 4

1

7

High-throughput

0.479

High

691431

RM35
Large ribosomal subunit protein mL38

1

1

High-throughput

0.479

High

691441

MAK21
Ribosome biogenesis protein MAK21

1

7

High-throughput

0.479

High

392350

H2A2
Histone H2A.2

1

4

High-throughput

0.470

High

691374

STM1
Suppressor protein STM1

1

2

High-throughput

0.470

High

691369

RM17
Large ribosomal subunit protein mL46

1

0

High-throughput

0.458

High

691382

RN49
Large ribosomal subunit protein bL21m

1

0

High-throughput

0.458

High

691403

RM22
Large ribosomal subunit protein uL22m

1

0

High-throughput

0.458

High

691412

RM13
Large ribosomal subunit protein mL50

1

0

High-throughput

0.458

High

691414

TMA23
Protein TMA23

1

0

High-throughput

0.458

High

691423

RSA3
Ribosome assembly protein 3

1

0

High-throughput

0.458

High

691435

NOP8
60S ribosome subunit biogenesis protein NOP8

1

0

High-throughput

0.458

High

691428

FKBP4
FK506-binding protein 4

1

1

High-throughput

0.457

High

399374

RLA0
Large ribosomal subunit protein uL10

1

5

High-throughput

0.445

High

498844

RL4A
Large ribosomal subunit protein uL4A

1

6

High-throughput

0.445

High

640879

RL5
Large ribosomal subunit protein uL18

1

3

High-throughput

0.445

High

691390

RL4B
Large ribosomal subunit protein uL4B

1

6

High-throughput

0.445

High

691409

SEN1
Helicase SEN1

1

3

Small-scale

0.445

High

339516

CDK1
Cyclin-dependent kinase 1

1

3

High-throughput

0.437

High

557942

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

3

High-throughput

0.437

High

604518

RPA2
DNA-directed RNA polymerase I subunit RPA135

1

1

High-throughput

0.437

High

661647

TF2B
Transcription initiation factor IIB

1

5

High-throughput

0.437

High

663827

TF3B
Transcription factor IIIB 70 kDa subunit

1

5

High-throughput

0.437

High

680531

HS104
Heat shock protein 104

1

3

High-throughput

0.437

High

691357

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

3

High-throughput

0.437

High

691364

EAP1
Protein EAP1

1

2

High-throughput

0.437

High

691375

LAA1
AP-1 accessory protein LAA1

1

3

High-throughput

0.437

High

691380

DSN1
Kinetochore-associated protein DSN1

1

3

High-throughput

0.437

High

691388

MOG1
Nuclear import protein MOG1

1

2

High-throughput

0.437

High

691402

GIS2
Zinc finger protein GIS2

1

7

High-throughput

0.437

High

691406

APJ1
J domain-containing protein APJ1

1

4

High-throughput

0.437

High

691407

SAM50
Sorting assembly machinery 50 kDa subunit

1

3

High-throughput

0.437

High

691408

NUM1
Nuclear migration protein NUM1

1

6

High-throughput

0.437

High

691422

HRQ1
ATP-dependent helicase HRQ1

1

7

Small-scale

0.437

High

691426

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

1

High-throughput

0.437

High

691427

PEX30
Peroxisomal membrane protein PEX30

1

1

Small-scale

0.437

High

691429

TFC6
Transcription factor tau 91 kDa subunit

1

1

High-throughput

0.437

High

691432

VAM6
Vacuolar morphogenesis protein 6

1

1

High-throughput

0.437

High

691436

SGO1
Shugoshin

1

3

High-throughput

0.437

High

691438

NCBP2
Nuclear cap-binding protein subunit 2

1

3

High-throughput

0.437

High

691439

AP3D
AP-3 complex subunit delta

1

3

High-throughput

0.437

High

478015

HSP77
Import motor subunit, mitochondrial

1

2

High-throughput

0.407

High

493464

HSP72
Heat shock protein SSA2

1

5

High-throughput

0.407

High

633926

GBP2
Serine/arginine

1

2

High-throughput

0.407

High

691356

BRR2
Pre-mRNA-splicing helicase BRR2

1

4

High-throughput

0.407

High

691360

PRP8
Pre-mRNA-splicing factor 8

1

1

High-throughput

0.407

High

691391

IMDH4
Inosine-5'-monophosphate dehydrogenase 4

1

2

High-throughput

0.407

High

691392

IMDH3
Inosine-5'-monophosphate dehydrogenase 3

1

2

High-throughput

0.407

High

691442

SMT3
Ubiquitin-like protein SMT3

2

0

High-throughput

0.313

High

691417

MUS81
Crossover junction endonuclease MUS81

1

0

High-throughput

0.279

Low

691401

ENG1
Glucan endo-1,3-beta-D-glucosidase 1

1

0

High-throughput

0.269

Low

691434

COQ10
Coenzyme Q-binding protein COQ10, mitochondrial

1

0

High-throughput

0.269

Low

691447

YD381
Uncharacterized mitochondrial outer membrane protein YDR381C-A

1

0

High-throughput

0.269

Low

419460

PDE2
3',5'-cyclic-nucleotide phosphodiesterase 2

1

0

High-throughput

0.249

Low

526968

TBP
TATA-box-binding protein

1

0

High-throughput

0.249

Low

664702

BMH1
Protein BMH1

1

0

High-throughput

0.249

Low

691385

RPA43
DNA-directed RNA polymerase I subunit RPA43

1

0

Small-scale

0.232

Low

691440

NSL1
Kinetochore-associated protein NSL1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024