Protein: MRT4
Ribosome assembly factor MRT4 (mRNA turnover protein 4)

Gene: MRT4
Organism: Saccharomyces cerevisiae S288C
Interactions: 196
UniProt ID: P33201

Gene Ontology (top 5):
GO:0000055 - ribosomal large subunit export from nucleus
GO:0000956 - nuclear-transcribed mRNA catabolic process
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

703108

ARX1
Probable metalloprotease ARX1

10

3

Small-scale

0.750

High

703083

PESC
Pescadillo homolog

9

2

Small-scale

0.745

High

703086

NOG2
Nucleolar GTP-binding protein 2

8

6

Small-scale

0.744

High

703146

IF6
Eukaryotic translation initiation factor 6

7

2

Small-scale

0.743

High

703057

NSA2
Ribosome biogenesis protein NSA2

6

2

Small-scale

0.729

High

703065

NOP2
25S rRNA

6

4

Small-scale

0.729

High

703050

RIX1
Pre-rRNA-processing protein RIX1

6

1

Small-scale

0.726

High

703103

NOG1
Nucleolar GTP-binding protein 1

6

7

Small-scale

0.721

High

703045

CIC1
Proteasome-interacting protein CIC1

5

2

Small-scale

0.709

High

703125

BUD20
Bud site selection protein 20

6

0

Small-scale

0.702

High

630854

NLE1
Ribosome assembly protein 4

5

7

Small-scale

0.702

High

703056

NUG1
Nuclear GTP-binding protein NUG1

5

6

Small-scale

0.702

High

703107

HAS1
ATP-dependent RNA helicase HAS1

5

11

Small-scale

0.702

High

703054

NOC2
Nucleolar complex protein 2

4

2

Small-scale

0.686

High

703034

RPF2
Ribosome biogenesis protein RPF2

4

2

Small-scale

0.683

High

703124

RLP24
Ribosome biogenesis protein RLP24

4

7

Small-scale

0.683

High

703046

SSF1
Ribosome biogenesis protein SSF1

4

2

Small-scale

0.676

High

703080

NSA1
Ribosome biogenesis protein NSA1

4

2

Small-scale

0.676

High

367904

EF1A
Elongation factor 1-alpha

1

3

High-throughput

0.665

High

703089

NOP13
Nucleolar protein 13

3

2

Small-scale

0.656

High

703114

ERB1
Ribosome biogenesis protein ERB1

3

6

Small-scale

0.656

High

703081

LSG1
Large subunit GTPase 1

3

6

Small-scale

0.650

High

638696

SPB4
ATP-dependent rRNA helicase SPB4

3

8

High-throughput

0.640

High

640891

RL5
Large ribosomal subunit protein uL18

3

2

Small-scale

0.640

High

703064

RLP7
Ribosome biogenesis protein RLP7

3

6

Small-scale

0.640

High

703073

ALB1
Ribosome biogenesis protein ALB1

3

1

Small-scale

0.640

High

703090

NOP15
Ribosome biogenesis protein 15

3

2

Small-scale

0.640

High

703058

SSB2
Ribosome-associated molecular chaperone SSB2

3

2

High-throughput

0.634

High

399390

RLA0
Large ribosomal subunit protein uL10

1

2

Small-scale

0.618

High

481887

RL12B
Large ribosomal subunit protein uL11B

1

2

Small-scale

0.618

High

703023

MRT4
Ribosome assembly factor MRT4

1

2

High-throughput

0.618

High

703105

RLI1
Translation initiation factor RLI1

1

2

Small-scale

0.618

High

703127

BRX1
Ribosome biogenesis protein BRX1

2

11

High-throughput

0.611

High

703137

YTM1
Ribosome biogenesis protein YTM1

2

8

High-throughput

0.611

High

703049

NMD3
60S ribosomal export protein NMD3

2

2

Small-scale

0.601

High

703068

LOC1
60S ribosomal subunit assembly/export protein LOC1

2

0

High-throughput

0.585

High

481311

RL2A
Large ribosomal subunit protein uL2A

3

2

Small-scale

0.585

High

703132

RS10A
Small ribosomal subunit protein eS10A

3

3

Small-scale

0.585

High

405158

RL17A
Large ribosomal subunit protein uL22A

2

4

Small-scale

0.584

High

407822

RS13
Small ribosomal subunit protein uS15

2

2

Small-scale

0.584

High

524241

CAF20
Cap-associated protein CAF20

2

1

High-throughput

0.584

High

534930

RL3
Large ribosomal subunit protein uL3

2

3

Small-scale

0.584

High

557970

RPB3
DNA-directed RNA polymerase II subunit RPB3

2

2

Small-scale

0.584

High

594026

MAK11
Protein MAK11

2

8

Small-scale

0.584

High

631770

RS2
Small ribosomal subunit protein uS5

2

2

Small-scale

0.584

High

703031

RL14A
Large ribosomal subunit protein eL14A

2

4

Small-scale

0.584

High

703042

ENP1
Essential nuclear protein 1

2

1

High-throughput

0.584

High

703082

CGR1
rRNA-processing protein CGR1

2

1

Small-scale

0.584

High

703084

SDA1
Protein SDA1

2

2

Small-scale

0.584

High

703088

IPI3
Pre-rRNA-processing protein IPI3

2

5

Small-scale

0.584

High

703109

RRP17
Ribosomal RNA-processing protein 17

2

1

High-throughput

0.584

High

703123

NOC3
Nucleolar complex-associated protein 3

2

3

Small-scale

0.584

High

703142

MAK21
Ribosome biogenesis protein MAK21

2

6

High-throughput

0.584

High

703143

DBP10
ATP-dependent RNA helicase DBP10

2

5

Small-scale

0.584

High

703048

RPF1
Ribosome production factor 1

2

2

High-throughput

0.571

High

703133

RRS1
Regulator of ribosome biosynthesis

2

2

High-throughput

0.571

High

703136

MDN1
Midasin

2

0

Small-scale

0.559

High

404818

RL9A
Large ribosomal subunit protein uL6A

1

3

High-throughput

0.553

High

675918

XPO1
Exportin-1

1

3

High-throughput

0.536

High

703041

IMB2
Importin subunit beta-2

1

2

High-throughput

0.536

High

703079

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

1

1

High-throughput

0.536

High

703085

BRE5
UBP3-associated protein BRE5

1

3

High-throughput

0.536

High

703098

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

4

High-throughput

0.536

High

703131

HRK1
Serine/threonine-protein kinase HRK1

1

3

High-throughput

0.536

High

382727

RL24A
Large ribosomal subunit protein eL24A

2

7

Small-scale

0.533

High

404992

RL6B
Large ribosomal subunit protein eL6B

2

4

Small-scale

0.533

High

478862

RL20B
Large ribosomal subunit protein eL20B

2

2

Small-scale

0.533

High

564256

RL8A
Large ribosomal subunit protein eL8A

2

5

Small-scale

0.533

High

644987

RL16A
Large ribosomal subunit protein uL13A

2

4

Small-scale

0.533

High

667146

RL8B
Large ribosomal subunit protein eL8B

2

5

Small-scale

0.533

High

703101

RL6A
Large ribosomal subunit protein eL6A

2

4

Small-scale

0.533

High

703144

RRP36
rRNA biogenesis protein RRP36

1

0

Small-scale

0.513

High

703061

MAM33
Mitochondrial acidic protein MAM33

1

0

High-throughput

0.493

High

141238

RS9A
Small ribosomal subunit protein uS4A

1

3

High-throughput

0.479

High

355425

H2B1
Histone H2B.1

1

1

High-throughput

0.479

High

356367

H4
Histone H4

1

1

High-throughput

0.479

High

357650

RL28
Large ribosomal subunit protein uL15

1

2

Small-scale

0.479

High

383042

RL25
Large ribosomal subunit protein uL23

1

3

High-throughput

0.479

High

392368

H2A2
Histone H2A.2

1

4

High-throughput

0.479

High

404537

RL7A
Large ribosomal subunit protein uL30A

1

6

High-throughput

0.479

High

405526

RL26A
Large ribosomal subunit protein uL24A

1

4

High-throughput

0.479

High

405973

RL33A
Large ribosomal subunit protein eL33A

1

2

High-throughput

0.479

High

406922

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.479

High

408312

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

2

High-throughput

0.479

High

413406

RS14A
Small ribosomal subunit protein uS11A

1

3

High-throughput

0.479

High

480008

RS6A
Small ribosomal subunit protein eS6A

1

2

High-throughput

0.479

High

481132

RL1A
Large ribosomal subunit protein uL1A

1

5

Small-scale

0.479

High

482171

RS18A
Small ribosomal subunit protein uS13A

1

1

High-throughput

0.479

High

498862

RL4A
Large ribosomal subunit protein uL4A

1

5

Small-scale

0.479

High

501201

MAK16
Protein MAK16

1

1

High-throughput

0.479

High

597815

PWP1
Periodic tryptophan protein 1

1

8

High-throughput

0.479

High

606603

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

3

High-throughput

0.479

High

627868

SIS1
Protein SIS1

1

2

High-throughput

0.479

High

634389

SPB1
27S pre-rRNA

1

2

High-throughput

0.479

High

634538

KRR1
KRR1 small subunit processome component

1

2

High-throughput

0.479

High

645342

RS7A
Small ribosomal subunit protein eS7A

1

1

High-throughput

0.479

High

650259

SPT5
Transcription elongation factor SPT5

1

1

High-throughput

0.479

High

661764

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.479

High

663833

TF3B
Transcription factor IIIB 70 kDa subunit

1

2

High-throughput

0.479

High

664730

BMH1
Protein BMH1

1

2

High-throughput

0.479

High

688172

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

1

High-throughput

0.479

High

698149

AFG2
ATPase family gene 2 protein

1

4

High-throughput

0.479

High

699658

DRS1
ATP-dependent RNA helicase DRS1

1

8

High-throughput

0.479

High

703025

URB1
Nucleolar pre-ribosomal-associated protein 1

1

2

Small-scale

0.479

High

703026

RRP1
Ribosomal RNA-processing protein 1

1

2

High-throughput

0.479

High

703027

RS27A
Small ribosomal subunit protein eS27A

1

1

High-throughput

0.479

High

703029

EBP2
rRNA-processing protein EBP2

1

1

High-throughput

0.479

High

703032

DBP7
ATP-dependent RNA helicase DBP7

1

9

High-throughput

0.479

High

703036

NOP4
Nucleolar protein 4

1

2

High-throughput

0.479

High

703037

GBLP
Small ribosomal subunit protein RACK1

1

8

High-throughput

0.479

High

703038

MAK5
ATP-dependent RNA helicase MAK5

1

9

High-throughput

0.479

High

703043

RS20
Small ribosomal subunit protein uS10

1

1

High-throughput

0.479

High

703044

RL14B
Large ribosomal subunit protein eL14B

1

4

Small-scale

0.479

High

703047

IPI1
Pre-rRNA-processing protein IPI1

1

1

High-throughput

0.479

High

703051

FKBP3
Peptidyl-prolyl cis-trans isomerase

1

2

High-throughput

0.479

High

703053

ECM1
Shuttling pre-60S factor ECM1

1

1

Small-scale

0.479

High

703059

ATAD2
ATPase histone chaperone YTA7

1

5

High-throughput

0.479

High

703063

ULP2
Ubiquitin-like-specific protease 2

1

2

High-throughput

0.479

High

703066

RL10
Large ribosomal subunit protein uL16

1

3

Small-scale

0.479

High

703067

UTP10
U3 small nucleolar RNA-associated protein 10

1

1

High-throughput

0.479

High

703072

RL17B
Large ribosomal subunit protein uL22B

1

4

High-throughput

0.479

High

703074

MTR4
ATP-dependent RNA helicase DOB1

1

4

Small-scale

0.479

High

703076

RS12
Small ribosomal subunit protein eS12

1

1

High-throughput

0.479

High

703077

RL37A
Large ribosomal subunit protein eL37A

1

2

High-throughput

0.479

High

703078

RL4B
Large ribosomal subunit protein uL4B

1

5

Small-scale

0.479

High

703087

GIS2
Zinc finger protein GIS2

1

6

High-throughput

0.479

High

703091

APJ1
J domain-containing protein APJ1

1

2

High-throughput

0.479

High

703093

RCM1
25S rRNA

1

4

High-throughput

0.479

High

703094

RL15B
Large ribosomal subunit protein eL15B

1

3

Small-scale

0.479

High

703096

RL34A
Large ribosomal subunit protein eL34A

1

4

High-throughput

0.479

High

703099

NOP3
Serine/arginine

1

5

Small-scale

0.479

High

703100

RS15
Small ribosomal subunit protein uS19

1

2

High-throughput

0.479

High

703102

XRN2
5'-3' exoribonuclease 2

1

1

High-throughput

0.479

High

703106

TOM1
E3 ubiquitin-protein ligase TOM1

1

3

High-throughput

0.479

High

703110

DHR1
Probable ATP-dependent RNA helicase DHR1

1

3

High-throughput

0.479

High

703111

RRB1
Ribosome assembly protein RRB1

1

3

High-throughput

0.479

High

703112

PUF6
Pumilio homology domain family member 6

1

3

High-throughput

0.479

High

703113

UTP14
U3 small nucleolar RNA-associated protein 14

1

2

High-throughput

0.479

High

703115

RRP5
rRNA biogenesis protein RRP5

1

4

High-throughput

0.479

High

703117

FKBP4
FK506-binding protein 4

1

2

High-throughput

0.479

High

703118

JIP5
WD repeat-containing protein JIP5

1

3

High-throughput

0.479

High

703119

DBP9
ATP-dependent RNA helicase DBP9

1

6

High-throughput

0.479

High

703121

NOC4
Nucleolar complex protein 4

1

6

High-throughput

0.479

High

703122

VAM6
Vacuolar morphogenesis protein 6

1

1

High-throughput

0.479

High

703126

NOP12
Nucleolar protein 12

1

3

High-throughput

0.479

High

703128

REXO4
RNA exonuclease 4

1

2

High-throughput

0.479

High

703129

SGO1
Shugoshin

1

1

High-throughput

0.479

High

703134

NIP7
60S ribosome subunit biogenesis protein NIP7

1

2

High-throughput

0.479

High

703135

BMS1
Ribosome biogenesis protein BMS1

1

3

High-throughput

0.479

High

703138

NOP53
Ribosome biogenesis protein NOP53

1

1

High-throughput

0.479

High

703140

SCC1
Sister chromatid cohesion protein 1

1

1

High-throughput

0.479

High

703141

YRA1
RNA annealing protein YRA1

1

2

High-throughput

0.479

High

703145

NOP58
Nucleolar protein 58

1

2

High-throughput

0.479

High

630464

RRP7
Ribosomal RNA-processing protein 7

1

0

Small-scale

0.458

High

703030

RRP14
Ribosomal RNA-processing protein 14

1

0

High-throughput

0.458

High

703040

YBC8
UPF0642 protein YBL028C

1

0

High-throughput

0.458

High

703055

NOP16
Nucleolar protein 16

1

0

High-throughput

0.458

High

703060

BMT5
25S rRNA

1

0

High-throughput

0.458

High

703075

DENR
Translation machinery-associated protein 22

1

0

Small-scale

0.458

High

703104

ESP1
Separin

1

0

High-throughput

0.458

High

703116

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.458

High

703120

RRP15
Ribosomal RNA-processing protein 15

1

0

High-throughput

0.458

High

703130

TMA16
Translation machinery-associated protein 16

1

0

High-throughput

0.458

High

703139

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.458

High

703147

MEX67
mRNA export factor MEX67

1

0

Small-scale

0.458

High

490756

HSP71
Heat shock protein SSA1

1

2

High-throughput

0.445

High

493554

HSP72
Heat shock protein SSA2

1

2

High-throughput

0.445

High

510748

SSB1
Ribosome-associated molecular chaperone SSB1

1

2

High-throughput

0.445

High

694382

HSP7F
Heat shock protein homolog SSE1

1

4

High-throughput

0.445

High

703033

SET3
SET domain-containing protein 3

1

3

High-throughput

0.445

High

703097

SEN1
Helicase SEN1

1

1

Small-scale

0.445

High

357969

RS17A
Small ribosomal subunit protein eS17A

1

1

High-throughput

0.437

High

406313

RL15A
Large ribosomal subunit protein eL15A

1

3

Small-scale

0.437

High

406501

RL22A
Large ribosomal subunit protein eL22A

1

3

Small-scale

0.437

High

425853

RS19A
Small ribosomal subunit protein eS19A

1

1

High-throughput

0.437

High

470956

RS22A
Small ribosomal subunit protein uS8A

1

1

High-throughput

0.437

High

471756

RL27A
Large ribosomal subunit protein eL27A

1

1

Small-scale

0.437

High

472106

RL31A
Large ribosomal subunit protein eL31A

1

2

High-throughput

0.437

High

480574

RS8A
Small ribosomal subunit protein eS8A

1

2

High-throughput

0.437

High

481614

RL18B
Large ribosomal subunit protein eL18B

1

2

Small-scale

0.437

High

621456

RL24B
Large ribosomal subunit protein eL24B

1

7

Small-scale

0.437

High

645186

RL16B
Large ribosomal subunit protein uL13B

1

4

Small-scale

0.437

High

700304

RSSA1
Small ribosomal subunit protein uS2A

1

1

High-throughput

0.437

High

703024

RS3A1
Small ribosomal subunit protein eS1A

1

2

High-throughput

0.437

High

703028

EAP1
Protein EAP1

1

1

High-throughput

0.437

High

703035

LONM
Lon protease homolog, mitochondrial

1

4

High-throughput

0.437

High

703052

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.437

High

703062

RL34B
Large ribosomal subunit protein eL34B

1

4

High-throughput

0.437

High

703069

RS10B
Small ribosomal subunit protein eS10B

1

3

Small-scale

0.437

High

703092

SAM50
Sorting assembly machinery 50 kDa subunit

1

1

High-throughput

0.437

High

703095

RL22B
Large ribosomal subunit protein eL22B

1

3

Small-scale

0.437

High

703071

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.426

High

703070

SPC1
Signal peptidase complex subunit 1

1

0

High-throughput

0.269

Low

703039

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

697037

YEF1
ATP-NADH kinase YEF1

1

0

High-throughput

0.238

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024