Protein: PRS6B
26S proteasome regulatory subunit 6B homolog (Protein YNT1) (Tat-binding homolog 2)

Gene: PRS6B, RPT3
Organism: Saccharomyces cerevisiae S288C
Interactions: 182
UniProt ID: P33298

Gene Ontology (top 5):
GO:0000502 - proteasome complex
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006511 - ubiquitin-dependent protein catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

703814

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

24

20

Small-scale

0.990

High

703773

PRS7
26S proteasome regulatory subunit 7 homolog

15

20

Small-scale

0.984

High

703565

PRS6A
26S proteasome regulatory subunit 6A

12

19

Small-scale

0.980

High

703841

PRS8
26S proteasome regulatory subunit 8 homolog

11

19

Small-scale

0.978

High

703831

PRS10
26S proteasome subunit RPT4

9

19

Small-scale

0.971

High

697066

RAD23
UV excision repair protein RAD23

6

20

Small-scale

0.945

High

703815

UBP6
Ubiquitin carboxyl-terminal hydrolase 6

6

10

High-throughput

0.945

High

703805

PRS4
26S proteasome regulatory subunit 4 homolog

6

19

Small-scale

0.943

High

703852

RPN7
26S proteasome regulatory subunit RPN7

4

20

High-throughput

0.900

High

703772

PRS6B
26S proteasome regulatory subunit 6B homolog

4

18

Small-scale

0.894

High

703860

RPN8
26S proteasome regulatory subunit RPN8

4

19

Small-scale

0.892

High

604774

PSB4
Proteasome subunit beta type-4

4

20

Small-scale

0.881

High

619439

PSA2
Proteasome subunit alpha type-2

3

20

Small-scale

0.827

High

703804

PSA4
Proteasome subunit alpha type-4

2

20

High-throughput

0.789

High

703868

RUVB2
RuvB-like protein 2

2

3

High-throughput

0.767

High

703823

PSD10
Probable 26S proteasome regulatory subunit p28

15

7

Small-scale

0.765

High

703796

RPN1
26S proteasome regulatory subunit RPN1

14

20

Small-scale

0.761

High

703797

RPN10
26S proteasome regulatory subunit RPN10

7

16

Small-scale

0.749

High

703788

HSM3
DNA mismatch repair protein HSM3

8

1

Small-scale

0.747

High

703865

RPN5
26S proteasome regulatory subunit RPN5

7

20

Small-scale

0.747

High

693270

RPN2
26S proteasome regulatory subunit RPN2

8

20

Small-scale

0.745

High

703867

RPN6
26S proteasome regulatory subunit RPN6

6

20

Small-scale

0.734

High

703828

RPN14
26S proteasome regulatory subunit RPN14

6

11

Small-scale

0.733

High

703849

RPN9
26S proteasome regulatory subunit RPN9

5

13

Small-scale

0.722

High

691455

RPN12
26S proteasome regulatory subunit RPN12

5

6

Small-scale

0.716

High

141842

RPN13
26S proteasome regulatory subunit RPN13

5

1

Small-scale

0.713

High

703808

PSMD9
Probable 26S proteasome regulatory subunit p27

5

9

Small-scale

0.709

High

703791

RFC3
Replication factor C subunit 3

1

7

High-throughput

0.691

High

703806

RFC4
Replication factor C subunit 4

1

2

High-throughput

0.691

High

294111

SEM1
26S proteasome complex subunit SEM1

4

1

Small-scale

0.683

High

703801

RPN3
26S proteasome regulatory subunit RPN3

4

11

Small-scale

0.683

High

703820

DSK2
Ubiquitin domain-containing protein DSK2

1

20

Small-scale

0.681

High

703794

ECM29
Proteasome component ECM29

3

6

High-throughput

0.656

High

477200

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

20

High-throughput

0.647

High

420480

RAD3
General transcription and DNA repair factor IIH helicase subunit XPD

3

0

High-throughput

0.629

High

632558

RAD51
DNA repair protein RAD51

2

2

High-throughput

0.621

High

657219

URA7
CTP synthase 1

2

2

High-throughput

0.621

High

597220

PSA7
Probable proteasome subunit alpha type-7

1

20

High-throughput

0.618

High

597305

PSA1
Proteasome subunit alpha type-1

1

20

High-throughput

0.618

High

619346

PSA3
Proteasome subunit alpha type-3

1

20

High-throughput

0.618

High

625923

PSB2
Proteasome subunit beta type-2

1

20

High-throughput

0.618

High

632477

PSB3
Proteasome subunit beta type-3

1

20

High-throughput

0.618

High

675406

PSB5
Proteasome subunit beta type-5

1

20

High-throughput

0.618

High

675455

PSB7
Proteasome subunit beta type-7

1

20

High-throughput

0.618

High

680574

HS104
Heat shock protein 104

1

4

High-throughput

0.618

High

689166

PSA5
Proteasome subunit alpha type-5

1

20

High-throughput

0.618

High

703790

PSB1
Proteasome subunit beta type-1

1

20

High-throughput

0.618

High

703803

PSA6
Proteasome subunit alpha type-6

1

20

High-throughput

0.618

High

703847

RUVB1
RuvB-like protein 1

1

3

High-throughput

0.618

High

521125

RAD50
DNA repair protein RAD50

2

0

High-throughput

0.602

High

366044

HSP82
ATP-dependent molecular chaperone HSP82

2

7

High-throughput

0.594

High

703786

CENPU
Inner kinetochore subunit AME1

2

0

Small-scale

0.594

High

703812

MPG1
Mannose-1-phosphate guanyltransferase

2

0

High-throughput

0.592

High

687913

IMB3
Importin subunit beta-3

2

1

High-throughput

0.588

High

703833

CUZ1
CDC48-associated ubiquitin-like/zinc finger protein 1

2

7

Small-scale

0.584

High

490760

HSP71
Heat shock protein SSA1

2

7

High-throughput

0.552

High

703844

SKY1
Serine/threonine-protein kinase SKY1

1

6

Small-scale

0.541

High

343286

TRPG
Multifunctional tryptophan biosynthesis protein [Includes: Anthranilate synthase component 2

1

1

High-throughput

0.536

High

372816

CARB
Carbamoyl phosphate synthase arginine-specific large chain

1

1

High-throughput

0.536

High

389878

VDAC1
Mitochondrial outer membrane protein porin 1

1

1

High-throughput

0.536

High

454585

TBA3
Tubulin alpha-3 chain

1

2

High-throughput

0.536

High

549721

STI1
Heat shock protein STI1

1

9

High-throughput

0.536

High

605509

DBF2
Cell cycle protein kinase DBF2

1

8

High-throughput

0.536

High

615252

IF5A1
Eukaryotic translation initiation factor 5A-1

1

1

High-throughput

0.536

High

689323

ARP2
Actin-related protein 2

1

3

High-throughput

0.536

High

693091

CDC5
Cell cycle serine/threonine-protein kinase CDC5/MSD2

1

2

Small-scale

0.536

High

697285

RAD24
Checkpoint protein RAD24

1

4

High-throughput

0.536

High

698513

KU70
ATP-dependent DNA helicase II subunit 1

1

1

High-throughput

0.536

High

703780

LHS1
Heat shock protein 70 homolog LHS1

1

8

High-throughput

0.536

High

703798

SPT8
Transcription factor SPT8

1

1

High-throughput

0.536

High

703824

UBC12
NEDD8-conjugating enzyme UBC12

1

4

High-throughput

0.536

High

703832

PPID
Peptidyl-prolyl cis-trans isomerase CPR6

1

1

High-throughput

0.536

High

703840

SLT2
Mitogen-activated protein kinase SLT2/MPK1

1

4

High-throughput

0.536

High

703870

SUS1
Transcription and mRNA export factor SUS1

1

1

High-throughput

0.536

High

703845

ESC1
Silent chromatin protein ESC1

2

5

High-throughput

0.533

High

627873

SIS1
Protein SIS1

1

5

High-throughput

0.515

High

597573

FAR1
Cyclin-dependent kinase inhibitor FAR1

1

0

High-throughput

0.513

High

703809

MKT1
Post-transcriptional regulator MKT1

1

0

High-throughput

0.513

High

703826

MSN5
Protein MSN5

1

0

High-throughput

0.513

High

703830

BUD32
EKC/KEOPS complex subunit BUD32

1

0

High-throughput

0.513

High

703862

MDN1
Midasin

1

0

High-throughput

0.513

High

703864

RAD59
DNA repair protein RAD59

1

0

High-throughput

0.513

High

381537

GAL4
Regulatory protein GAL4

1

1

Small-scale

0.501

High

367907

EF1A
Elongation factor 1-alpha

1

1

High-throughput

0.500

High

424434

PYR1
Multifunctional protein URA2

1

1

High-throughput

0.500

High

440006

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

2

High-throughput

0.500

High

555938

VATB
V-type proton ATPase subunit B

1

4

High-throughput

0.500

High

594309

PP11
Serine/threonine-protein phosphatase PP1-1

1

4

High-throughput

0.500

High

597816

PWP1
Periodic tryptophan protein 1

1

15

High-throughput

0.500

High

632524

DMC1
Meiotic recombination protein DMC1

1

2

High-throughput

0.500

High

633083

MAS5
Mitochondrial protein import protein MAS5

1

5

High-throughput

0.500

High

703775

MDJ1
DnaJ homolog 1, mitochondrial

1

6

High-throughput

0.500

High

703784

IMB2
Importin subunit beta-2

1

1

High-throughput

0.500

High

703818

TCPQ
T-complex protein 1 subunit theta

1

3

High-throughput

0.500

High

703851

ERB1
Ribosome biogenesis protein ERB1

1

6

High-throughput

0.500

High

703858

THI20
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI20

1

1

High-throughput

0.500

High

657045

IDH2
Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial

1

2

High-throughput

0.489

High

703811

COPB2
Coatomer subunit beta'

1

5

High-throughput

0.489

High

381444

GAL1
Galactokinase

1

0

High-throughput

0.479

High

498484

METK1
S-adenosylmethionine synthase 1

1

0

High-throughput

0.479

High

562353

PFKA2
ATP-dependent 6-phosphofructokinase subunit beta

1

0

High-throughput

0.479

High

588018

HSP60
Heat shock protein 60, mitochondrial

1

0

High-throughput

0.479

High

703810

PAC11
WD repeat-containing protein PAC11

1

0

High-throughput

0.479

High

141240

RS9A
Small ribosomal subunit protein uS4A

1

4

High-throughput

0.479

High

339545

CDK1
Cyclin-dependent kinase 1

1

5

High-throughput

0.479

High

406924

RS3
Small ribosomal subunit protein uS3

1

5

High-throughput

0.479

High

407824

RS13
Small ribosomal subunit protein uS15

1

2

High-throughput

0.479

High

482173

RS18A
Small ribosomal subunit protein uS13A

1

1

High-throughput

0.479

High

524243

CAF20
Cap-associated protein CAF20

1

1

High-throughput

0.479

High

543462

HSC82
ATP-dependent molecular chaperone HSC82

1

7

High-throughput

0.479

High

566153

EST1
Telomere elongation protein EST1

1

1

High-throughput

0.479

High

606605

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

2

High-throughput

0.479

High

661769

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.479

High

663834

TF3B
Transcription factor IIIB 70 kDa subunit

1

3

High-throughput

0.479

High

691955

NAB2
Nuclear polyadenylated RNA-binding protein NAB2

1

1

High-throughput

0.479

High

700819

SMY2
Protein SMY2

1

1

High-throughput

0.479

High

703776

SPT10
Protein SPT10

1

1

High-throughput

0.479

High

703777

SPT21
Protein SPT21

1

1

High-throughput

0.479

High

703778

RS27A
Small ribosomal subunit protein eS27A

1

2

High-throughput

0.479

High

703779

CENPA
Histone H3-like centromeric protein CSE4

1

7

High-throughput

0.479

High

703782

TCD2
tRNA threonylcarbamoyladenosine dehydratase 2

1

1

High-throughput

0.479

High

703789

RCK2
Serine/threonine-protein kinase RCK2

1

4

High-throughput

0.479

High

703795

TCD1
tRNA threonylcarbamoyladenosine dehydratase 1

1

1

High-throughput

0.479

High

703817

MPS3
Spindle pole body assembly component MPS3

1

1

High-throughput

0.479

High

703821

RS12
Small ribosomal subunit protein eS12

1

3

High-throughput

0.479

High

703822

VATG
V-type proton ATPase subunit G

1

1

High-throughput

0.479

High

703827

INO80
Chromatin-remodeling ATPase INO80

1

3

Small-scale

0.479

High

703834

APJ1
J domain-containing protein APJ1

1

5

High-throughput

0.479

High

703837

H3
Histone H3

1

7

High-throughput

0.479

High

703839

CDC14
Tyrosine-protein phosphatase CDC14

1

9

High-throughput

0.479

High

703843

RPN4
Protein RPN4

1

1

Small-scale

0.479

High

703850

DHR1
Probable ATP-dependent RNA helicase DHR1

1

1

High-throughput

0.479

High

703854

TFC6
Transcription factor tau 91 kDa subunit

1

1

High-throughput

0.479

High

703855

NAT3
N-terminal acetyltransferase B complex catalytic subunit NAT3

1

1

Small-scale

0.479

High

703863

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

1

High-throughput

0.479

High

703869

SMC6
Structural maintenance of chromosomes protein 6

1

2

High-throughput

0.479

High

594120

CKS1
Cyclin-dependent kinases regulatory subunit

1

0

Small-scale

0.458

High

688174

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

703785

AIM4
Altered inheritance of mitochondria protein 4

1

0

High-throughput

0.458

High

703799

DHH1
ATP-dependent RNA helicase DHH1

1

0

High-throughput

0.458

High

703816

MIC19
MICOS complex subunit MIC19

1

0

High-throughput

0.458

High

703829

MCY1
Putative mitochondrial cysteine synthase

1

0

High-throughput

0.458

High

703848

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

703853

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.458

High

703856

URN1
Pre-mRNA-splicing factor URN1

1

0

High-throughput

0.458

High

703859

SGO1
Shugoshin

1

0

High-throughput

0.458

High

703866

CSN10
COP9 signalosome complex subunit 10

1

0

Small-scale

0.458

High

378323

LEU3
3-isopropylmalate dehydrogenase

1

3

High-throughput

0.457

High

539968

EI2BA
Translation initiation factor eIF2B subunit alpha

1

1

High-throughput

0.457

High

630789

STDH
Catabolic L-serine/threonine dehydratase [Includes: L-serine dehydratase

1

1

High-throughput

0.457

High

703781

VPS21
Vacuolar protein sorting-associated protein 21

1

1

High-throughput

0.457

High

703783

AP3M
AP-3 complex subunit mu

1

1

High-throughput

0.457

High

703846

WDR59
Maintenance of telomere capping protein 5

1

14

High-throughput

0.457

High

703857

SHS1
Seventh homolog of septin 1

1

2

High-throughput

0.457

High

412544

CDC7
Cell division control protein 7

1

17

Small-scale

0.445

High

478049

HSP77
Import motor subunit, mitochondrial

1

9

High-throughput

0.445

High

695929

HSP79
Heat shock protein homolog SSE2

1

9

High-throughput

0.445

High

703774

SPT7
Transcriptional activator SPT7

1

4

High-throughput

0.445

High

703800

HSP7E
Heat shock protein SSC3, mitochondrial

1

9

High-throughput

0.445

High

703802

SSB2
Ribosome-associated molecular chaperone SSB2

1

7

High-throughput

0.445

High

703819

DPH4
Diphthamide biosynthesis protein 4

1

2

High-throughput

0.445

High

703842

GCN5
Histone acetyltransferase GCN5

1

3

High-throughput

0.445

High

405528

RL26A
Large ribosomal subunit protein uL24A

1

2

High-throughput

0.437

High

425855

RS19A
Small ribosomal subunit protein eS19A

1

2

High-throughput

0.437

High

472108

RL31A
Large ribosomal subunit protein eL31A

1

1

High-throughput

0.437

High

480010

RS6A
Small ribosomal subunit protein eS6A

1

3

High-throughput

0.437

High

645344

RS7A
Small ribosomal subunit protein eS7A

1

4

High-throughput

0.437

High

700307

RSSA1
Small ribosomal subunit protein uS2A

1

2

High-throughput

0.437

High

703807

MLP2
Protein MLP2

1

4

High-throughput

0.437

High

703813

UTP10
U3 small nucleolar RNA-associated protein 10

1

1

High-throughput

0.437

High

703838

NUM1
Nuclear migration protein NUM1

1

2

High-throughput

0.437

High

703861

RS10A
Small ribosomal subunit protein eS10A

1

4

High-throughput

0.437

High

703793

SYNC
Asparagine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.426

High

703825

PFD6
Prefoldin subunit 6

1

0

High-throughput

0.426

High

703787

ATG12
Ubiquitin-like protein ATG12

1

0

High-throughput

0.279

Low

619660

VAN1
Mannan polymerase I complex VAN1 subunit

1

0

High-throughput

0.261

Low

634280

MGR1
Mitochondrial inner membrane i-AAA protease supercomplex subunit MGR1

1

0

High-throughput

0.249

Low

703792

HXT5
Probable glucose transporter HXT5

1

0

High-throughput

0.249

Low

703835

SAM50
Sorting assembly machinery 50 kDa subunit

1

0

High-throughput

0.249

Low

427219

ILVB
Acetolactate synthase catalytic subunit, mitochondrial

1

0

High-throughput

0.232

Low

703836

TMEDA
Endoplasmic reticulum vesicle protein 25

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024