Protein: MFT1
THO complex subunit MFT1 (Mitochondrial fusion target protein 1)

Gene: MFT1
Organism: Saccharomyces cerevisiae S288C
Interactions: 105
UniProt ID: P33441

Gene Ontology (top 5):
GO:0000346 - transcription export complex
GO:0000445 - THO complex part of transcription export complex
GO:0000446 - nucleoplasmic THO complex
GO:0000781 - chromosome, telomeric region
GO:0003676 - nucleic acid binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

568865

HPR1
THO complex subunit HPR1

15

0

Small-scale

0.934

High

706159

THO2
THO complex subunit 2

10

0

Small-scale

0.926

High

141727

THP2
THO complex subunit THP2

10

0

Small-scale

0.923

High

706175

YRA1
RNA annealing protein YRA1

5

1

Small-scale

0.716

High

633933

GBP2
Serine/arginine

5

2

Small-scale

0.712

High

706170

SUB2
ATP-dependent RNA helicase SUB2

7

0

Small-scale

0.711

High

706161

TEX1
Protein TEX1

6

0

Small-scale

0.699

High

706139

HRB1
Serine/arginine

5

1

Small-scale

0.650

High

706131

MFT1
THO complex subunit MFT1

3

0

Small-scale

0.622

High

706174

NCBP2
Nuclear cap-binding protein subunit 2

2

0

Small-scale

0.559

High

493579

HSP72
Heat shock protein SSA2

2

1

High-throughput

0.549

High

510781

SSB1
Ribosome-associated molecular chaperone SSB1

2

1

High-throughput

0.549

High

706147

DLS1
Protein DLS1

1

0

High-throughput

0.493

High

341983

ATPB
ATP synthase subunit beta, mitochondrial

1

1

High-throughput

0.489

High

490784

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.489

High

693274

RPN2
26S proteasome regulatory subunit RPN2

1

1

High-throughput

0.489

High

706168

ATG17
Autophagy-related protein 17

1

0

High-throughput

0.486

High

409831

NOT2
General negative regulator of transcription subunit 2

1

0

Small-scale

0.458

High

557980

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

Small-scale

0.458

High

706132

NCBP1
Nuclear cap-binding protein complex subunit 1

1

0

Small-scale

0.458

High

706148

MLP2
Protein MLP2

1

0

High-throughput

0.458

High

706178

SMC6
Structural maintenance of chromosomes protein 6

1

0

High-throughput

0.458

High

706179

MEX67
mRNA export factor MEX67

1

0

High-throughput

0.458

High

565525

PHO85
Cyclin-dependent protein kinase PHO85

1

1

High-throughput

0.457

High

630991

KCC4
Probable serine/threonine-protein kinase KCC4

1

1

High-throughput

0.457

High

706136

KSP1
Serine/threonine-protein kinase KSP1

1

1

High-throughput

0.457

High

706166

PKH3
Serine/threonine-protein kinase PKH3

1

1

High-throughput

0.457

High

339552

CDK1
Cyclin-dependent kinase 1

1

1

Small-scale

0.439

High

554212

PRP16
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16

1

1

High-throughput

0.437

High

622308

PRP22
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP22

1

1

High-throughput

0.437

High

376711

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

0

High-throughput

0.426

High

555946

VATB
V-type proton ATPase subunit B

1

1

High-throughput

0.407

High

566558

VATA
V-type proton ATPase catalytic subunit A

1

2

High-throughput

0.407

High

694399

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.407

High

706138

RPN1
26S proteasome regulatory subunit RPN1

1

1

High-throughput

0.407

High

706145

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.407

High

706146

JEM1
DnaJ-like chaperone JEM1

1

1

High-throughput

0.407

High

706153

DPH4
Diphthamide biosynthesis protein 4

1

1

High-throughput

0.407

High

706154

HLJ1
Protein HLJ1

1

1

High-throughput

0.407

High

706163

ACAC
Acetyl-CoA carboxylase

1

1

High-throughput

0.407

High

357975

RS17A
Small ribosomal subunit protein eS17A

2

0

High-throughput

0.298

High

406931

RS3
Small ribosomal subunit protein uS3

2

0

High-throughput

0.298

High

420109

TOP2
DNA topoisomerase 2

1

0

High-throughput

0.279

Low

706134

EF1G2
Elongation factor 1-gamma 2

1

0

High-throughput

0.279

Low

706135

OLA1
Obg-like ATPase 1

1

0

High-throughput

0.279

Low

706156

IMDH3
Inosine-5'-monophosphate dehydrogenase 3

1

0

High-throughput

0.279

Low

706165

IMA1
Importin subunit alpha

1

0

High-throughput

0.279

Low

706152

CYP7
Peptidyl-prolyl cis-trans isomerase CYP7

1

0

High-throughput

0.269

Low

706171

ULS1
ATP-dependent helicase ULS1

1

0

High-throughput

0.269

Low

419848

SNF1
Carbon catabolite-derepressing protein kinase

1

0

High-throughput

0.261

Low

614597

KC11
Casein kinase I homolog 1

1

0

High-throughput

0.261

Low

648129

KCC1
Calcium/calmodulin-dependent protein kinase I

1

0

High-throughput

0.261

Low

698343

ELM1
Serine/threonine-protein kinase ELM1

1

0

High-throughput

0.261

Low

706158

ATG1
Serine/threonine-protein kinase ATG1

1

0

High-throughput

0.261

Low

706172

ESA1
Histone acetyltransferase ESA1

1

0

Small-scale

0.261

Low

706150

BUD27
Bud site selection protein 27

1

0

Small-scale

0.251

Low

706167

GIS1
Transcriptional activator/repressor GIS1

1

0

Small-scale

0.251

Low

141245

RS9A
Small ribosomal subunit protein uS4A

1

0

High-throughput

0.249

Low

383050

RL25
Large ribosomal subunit protein uL23

1

0

High-throughput

0.249

Low

405532

RL26A
Large ribosomal subunit protein uL24A

1

0

High-throughput

0.249

Low

409975

NOT3
General negative regulator of transcription subunit 3

1

0

Small-scale

0.249

Low

413414

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.249

Low

425859

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.249

Low

470963

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.249

Low

472113

RL31A
Large ribosomal subunit protein eL31A

1

0

High-throughput

0.249

Low

479716

RS4A
Small ribosomal subunit protein eS4A

1

0

High-throughput

0.249

Low

480017

RS6A
Small ribosomal subunit protein eS6A

1

0

High-throughput

0.249

Low

480581

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.249

Low

541590

CBS2
Cytochrome B translational activator protein CBS2

1

0

High-throughput

0.249

Low

645350

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.249

Low

661796

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

691959

NAB2
Nuclear polyadenylated RNA-binding protein NAB2

1

0

High-throughput

0.249

Low

706133

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.249

Low

706137

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.249

Low

706142

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

706143

GPB2
Guanine nucleotide-binding protein subunit beta 2

1

0

Small-scale

0.249

Low

706157

HFM1
ATP-dependent DNA helicase MER3

1

0

Small-scale

0.249

Low

706160

CAF40
Protein CAF40

1

0

Small-scale

0.249

Low

706162

YNO0
Uncharacterized protein YNL140C

1

0

High-throughput

0.249

Low

706164

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.249

Low

706169

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.249

Low

706173

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.249

Low

333749

ADH1
Alcohol dehydrogenase 1

1

0

High-throughput

0.232

Low

360826

TBB
Tubulin beta chain

1

0

High-throughput

0.232

Low

399397

RLA0
Large ribosomal subunit protein uL10

1

0

High-throughput

0.232

Low

407828

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.232

Low

424442

PYR1
Multifunctional protein URA2

1

0

High-throughput

0.232

Low

498486

METK1
S-adenosylmethionine synthase 1

1

0

High-throughput

0.232

Low

519920

TCPA
T-complex protein 1 subunit alpha

1

0

High-throughput

0.232

Low

540063

GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

1

0

High-throughput

0.232

Low

560621

BIP
Endoplasmic reticulum chaperone BiP

1

0

High-throughput

0.232

Low

633092

MAS5
Mitochondrial protein import protein MAS5

1

0

High-throughput

0.232

Low

640895

RL5
Large ribosomal subunit protein uL18

1

0

High-throughput

0.232

Low

644858

RS5
Small ribosomal subunit protein uS7

1

0

High-throughput

0.232

Low

667148

RL8B
Large ribosomal subunit protein eL8B

1

0

High-throughput

0.232

Low

704993

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.232

Low

706140

TCPB
T-complex protein 1 subunit beta

1

0

High-throughput

0.232

Low

706141

TCPD
T-complex protein 1 subunit delta

1

0

High-throughput

0.232

Low

706144

IMB4
Importin subunit beta-4

1

0

High-throughput

0.232

Low

706149

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.232

Low

706151

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.232

Low

706155

RL4B
Large ribosomal subunit protein uL4B

1

0

High-throughput

0.232

Low

706176

HSP42
Heat shock protein 42

1

0

High-throughput

0.232

Low

706177

PAA1
Polyamine N-acetyltransferase 1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024