Protein: FADD
FAS-associated death domain protein (FAS-associating death domain-containing protein) (Mediator of receptor induced toxicity)

Gene: FADD
Organism: Mus musculus
Interactions: 22
UniProt ID: Q61160

Gene Ontology (top 5):
GO:0001822 - kidney development
GO:0001916 - positive regulation of T cell mediated cytotoxicity
GO:0002821 - positive regulation of adaptive immune response
GO:0005123 - death receptor binding
GO:0005164 - tumor necrosis factor receptor binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1221632

RIPK1
Receptor-interacting serine/threonine-protein kinase 1

14

20

Small-scale

0.978

High

313448

CASP8
Caspase-8

10

17

Small-scale

0.970

High

1222372

RIPK3
Receptor-interacting serine/threonine-protein kinase 3

6

18

Small-scale

0.931

High

675223

TNR6
Tumor necrosis factor receptor superfamily member 6

4

20

Small-scale

0.881

High

205507

CFLAR
CASP8 and FADD-like apoptosis regulator

2

17

Small-scale

0.776

High

1222366

ATG5
Autophagy protein 5

2

4

Small-scale

0.621

High

148445

BIRC3
Baculoviral IAP repeat-containing protein 3

1

17

Small-scale

0.618

High

648055

MYD88
Myeloid differentiation primary response protein MyD88

1

7

Small-scale

0.618

High

669416

TNR1A
Tumor necrosis factor receptor superfamily member 1A

1

20

Small-scale

0.618

High

1209177

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

5

Small-scale

0.618

High

1222362

IRAK1
Interleukin-1 receptor-associated kinase 1

1

2

Small-scale

0.618

High

1222364

IRAK2
Interleukin-1 receptor-associated kinase-like 2

1

2

Small-scale

0.618

High

1222370

HIPK3
Homeodomain-interacting protein kinase 3

1

6

Small-scale

0.618

High

1222371

PIDD1
p53-induced death domain-containing protein 1

1

5

Small-scale

0.618

High

1222363

A16L1
Autophagy-related protein 16-1

1

2

Small-scale

0.536

High

1064114

KCMA1
Calcium-activated potassium channel subunit alpha-1

1

6

Small-scale

0.512

High

449246

TNFA
Tumor necrosis factor

1

15

Small-scale

0.479

High

1221458

TNAP3
Tumor necrosis factor alpha-induced protein 3

1

11

Small-scale

0.479

High

1222368

MLKL
Mixed lineage kinase domain-like protein

1

6

Small-scale

0.479

High

1222369

ATG7
Ubiquitin-like modifier-activating enzyme ATG7

1

1

Small-scale

0.479

High

1222367

ATG12
Ubiquitin-like protein ATG12

1

1

Small-scale

0.470

High

1222365

MLP3A
Microtubule-associated protein 1 light chain 3 alpha

1

13

Small-scale

0.437

High


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Last updated: 11Aug2025