Protein: SSF1
Ribosome biogenesis protein SSF1

Gene: SSF1
Organism: Saccharomyces cerevisiae S288C
Interactions: 171
UniProt ID: P38789

Gene Ontology (top 5):
GO:0000027 - ribosomal large subunit assembly
GO:0000463 - maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0005730 - nucleolus
GO:0008361 - regulation of cell size
GO:0019843 - rRNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

731806

EBP2
rRNA-processing protein EBP2

9

1

Small-scale

0.964

High

733815

RPF2
Ribosome biogenesis protein RPF2

7

1

Small-scale

0.952

High

754917

RRP15
Ribosomal RNA-processing protein 15

5

1

High-throughput

0.920

High

754857

RPF1
Ribosome production factor 1

5

1

Small-scale

0.903

High

732212

RRP14
Ribosomal RNA-processing protein 14

5

0

Small-scale

0.865

High

754935

SSF2
Ribosome biogenesis protein SSF2

2

2

High-throughput

0.776

High

754898

NOG1
Nucleolar GTP-binding protein 1

14

2

Small-scale

0.759

High

754883

PESC
Pescadillo homolog

13

1

Small-scale

0.755

High

534979

RL3
Large ribosomal subunit protein uL3

12

1

Small-scale

0.755

High

754942

IF6
Eukaryotic translation initiation factor 6

11

1

Small-scale

0.754

High

501214

MAK16
Protein MAK16

2

2

Small-scale

0.754

High

754856

SSF1
Ribosome biogenesis protein SSF1

2

2

Small-scale

0.754

High

754923

BRX1
Ribosome biogenesis protein BRX1

2

9

Small-scale

0.754

High

754937

MAK21
Ribosome biogenesis protein MAK21

11

3

Small-scale

0.752

High

754899

HAS1
ATP-dependent RNA helicase HAS1

10

8

Small-scale

0.749

High

754906

PUF6
Pumilio homology domain family member 6

8

2

Small-scale

0.742

High

754881

NSA1
Ribosome biogenesis protein NSA1

8

1

Small-scale

0.742

High

754933

YTM1
Ribosome biogenesis protein YTM1

7

2

Small-scale

0.740

High

754860

NOC2
Nucleolar complex protein 2

7

1

Small-scale

0.739

High

754870

RLP7
Ribosome biogenesis protein RLP7

7

3

Small-scale

0.737

High

754871

NOP2
25S rRNA

7

2

Small-scale

0.737

High

754929

RRS1
Regulator of ribosome biosynthesis

2

0

High-throughput

0.736

High

742011

NOP4
Nucleolar protein 4

6

2

Small-scale

0.722

High

754113

CIC1
Proteasome-interacting protein CIC1

6

2

Small-scale

0.722

High

754908

ERB1
Ribosome biogenesis protein ERB1

6

2

Small-scale

0.722

High

754940

DBP10
ATP-dependent RNA helicase DBP10

6

3

Small-scale

0.722

High

482866

RL35A
Large ribosomal subunit protein uL29A

6

1

Small-scale

0.721

High

699679

DRS1
ATP-dependent RNA helicase DRS1

5

7

Small-scale

0.703

High

754910

RRP5
rRNA biogenesis protein RRP5

5

1

Small-scale

0.699

High

754915

DBP9
ATP-dependent RNA helicase DBP9

4

4

Small-scale

0.678

High

754931

NIP7
60S ribosome subunit biogenesis protein NIP7

4

1

Small-scale

0.678

High

710878

URB1
Nucleolar pre-ribosomal-associated protein 1

5

0

High-throughput

0.676

High

703046

MRT4
Ribosome assembly factor MRT4

4

2

Small-scale

0.676

High

754864

NUG1
Nuclear GTP-binding protein NUG1

4

2

Small-scale

0.676

High

754920

NOC3
Nucleolar complex-associated protein 3

4

2

Small-scale

0.676

High

754921

RLP24
Ribosome biogenesis protein RLP24

4

1

Small-scale

0.676

High

754866

NSA2
Ribosome biogenesis protein NSA2

4

0

Small-scale

0.657

High

744188

MAK5
ATP-dependent RNA helicase MAK5

3

8

Small-scale

0.643

High

638745

SPB4
ATP-dependent rRNA helicase SPB4

3

7

High-throughput

0.640

High

715437

RRP1
Ribosomal RNA-processing protein 1

3

2

Small-scale

0.640

High

733128

DBP7
ATP-dependent RNA helicase DBP7

3

6

Small-scale

0.640

High

754874

LOC1
60S ribosomal subunit assembly/export protein LOC1

3

1

Small-scale

0.640

High

754891

NOP15
Ribosome biogenesis protein 15

3

2

High-throughput

0.640

High

564284

RL8A
Large ribosomal subunit protein eL8A

3

4

Small-scale

0.585

High

594037

MAK11
Protein MAK11

2

4

Small-scale

0.584

High

634405

SPB1
27S pre-rRNA

2

1

High-throughput

0.584

High

640937

RL5
Large ribosomal subunit protein uL18

2

1

Small-scale

0.584

High

754914

FKBP4
FK506-binding protein 4

2

1

Small-scale

0.584

High

549393

FBRL
rRNA 2'-O-methyltransferase fibrillarin

2

0

High-throughput

0.576

High

635120

YCQ6
Uncharacterized protein YCR016W

2

0

High-throughput

0.576

High

383131

RL25
Large ribosomal subunit protein uL23

2

1

High-throughput

0.571

High

560970

EF3A
Elongation factor 3A

2

0

High-throughput

0.563

High

748599

ENP1
Essential nuclear protein 1

2

0

High-throughput

0.559

High

754863

NOP16
Nucleolar protein 16

2

0

Small-scale

0.559

High

754876

URB2
Nucleolar pre-ribosomal-associated protein 2

2

0

High-throughput

0.559

High

754896

RL6A
Large ribosomal subunit protein eL6A

1

0

High-throughput

0.546

High

550027

CSK21
Casein kinase II subunit alpha

1

3

High-throughput

0.536

High

481154

RL1A
Large ribosomal subunit protein uL1A

2

4

Small-scale

0.533

High

704336

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

2

1

High-throughput

0.533

High

742781

GBLP
Small ribosomal subunit protein RACK1

2

2

High-throughput

0.533

High

534758

RL30
Large ribosomal subunit protein eL30

2

1

Small-scale

0.521

High

754897

RNT1
Ribonuclease 3

1

1

High-throughput

0.515

High

420564

SPT2
Protein SPT2

1

0

High-throughput

0.513

High

493903

HSP72
Heat shock protein SSA2

2

1

High-throughput

0.504

High

754927

DIA2
Protein DIA2

1

1

High-throughput

0.489

High

399456

RLA0
Large ribosomal subunit protein uL10

1

2

Small-scale

0.479

High

405183

RL17A
Large ribosomal subunit protein uL22A

1

1

Small-scale

0.479

High

407901

RS13
Small ribosomal subunit protein uS15

1

1

High-throughput

0.479

High

413493

RS14A
Small ribosomal subunit protein uS11A

1

1

High-throughput

0.479

High

480090

RS6A
Small ribosomal subunit protein eS6A

1

1

High-throughput

0.479

High

597836

PWP1
Periodic tryptophan protein 1

1

1

Small-scale

0.479

High

631863

RS2
Small ribosomal subunit protein uS5

1

1

High-throughput

0.479

High

634591

KRR1
KRR1 small subunit processome component

1

1

High-throughput

0.479

High

691373

NHP2
H/ACA ribonucleoprotein complex subunit NHP2

1

4

High-throughput

0.479

High

754858

FKBP3
Peptidyl-prolyl cis-trans isomerase

1

1

High-throughput

0.479

High

754862

SNU13
13 kDa ribonucleoprotein-associated protein

1

4

High-throughput

0.479

High

754872

RL10
Large ribosomal subunit protein uL16

1

1

Small-scale

0.479

High

754886

YG5X
Putative methyltransferase YGR283C

1

1

High-throughput

0.479

High

754888

DBP6
ATP-dependent RNA helicase DBP6

1

5

High-throughput

0.479

High

754904

DHR1
Probable ATP-dependent RNA helicase DHR1

1

1

High-throughput

0.479

High

754905

RRB1
Ribosome assembly protein RRB1

1

1

High-throughput

0.479

High

754918

NOC4
Nucleolar complex protein 4

1

3

High-throughput

0.479

High

754922

NOP12
Nucleolar protein 12

1

3

High-throughput

0.479

High

754924

REXO4
RNA exonuclease 4

1

2

High-throughput

0.479

High

754934

NOP53
Ribosome biogenesis protein NOP53

1

2

High-throughput

0.479

High

754941

NOP58
Nucleolar protein 58

1

1

High-throughput

0.479

High

754865

IMB4
Importin subunit beta-4

1

1

High-throughput

0.470

High

141317

RS9A
Small ribosomal subunit protein uS4A

1

0

High-throughput

0.458

High

482251

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.458

High

630192

RRP43
Exosome complex component RRP43

1

0

High-throughput

0.458

High

630859

NLE1
Ribosome assembly protein 4

1

0

High-throughput

0.458

High

645430

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.458

High

733656

LAS1
Protein LAS1

1

0

Small-scale

0.458

High

754867

UTP18
U3 small nucleolar RNA-associated protein 18

1

0

High-throughput

0.458

High

754873

UTP10
U3 small nucleolar RNA-associated protein 10

1

0

High-throughput

0.458

High

754884

SDA1
Protein SDA1

1

0

High-throughput

0.458

High

754885

PXR1
Protein PXR1

1

0

Small-scale

0.458

High

754889

NOP13
Nucleolar protein 13

1

0

High-throughput

0.458

High

754900

ARX1
Probable metalloprotease ARX1

1

0

High-throughput

0.458

High

754902

RRP17
Ribosomal RNA-processing protein 17

1

0

High-throughput

0.458

High

754903

UTP5
U3 small nucleolar RNA-associated protein 5

1

0

High-throughput

0.458

High

754907

UTP14
U3 small nucleolar RNA-associated protein 14

1

0

High-throughput

0.458

High

754912

RSA3
Ribosome assembly protein 3

1

0

High-throughput

0.458

High

754916

NEP1
Ribosomal RNA small subunit methyltransferase NEP1

1

0

High-throughput

0.458

High

754925

NOP8
60S ribosome subunit biogenesis protein NOP8

1

0

High-throughput

0.458

High

404574

RL7A
Large ribosomal subunit protein uL30A

1

3

High-throughput

0.445

High

754938

RL7B
Large ribosomal subunit protein uL30B

1

3

High-throughput

0.445

High

356461

H4
Histone H4

1

1

High-throughput

0.437

High

405608

RL26A
Large ribosomal subunit protein uL24A

1

1

High-throughput

0.437

High

407033

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.437

High

425938

RS19A
Small ribosomal subunit protein eS19A

1

1

High-throughput

0.437

High

472178

RL31A
Large ribosomal subunit protein eL31A

1

1

High-throughput

0.437

High

479105

RL43B
Large ribosomal subunit protein eL43B

1

1

Small-scale

0.437

High

480658

RS8A
Small ribosomal subunit protein eS8A

1

1

High-throughput

0.437

High

498918

RL4A
Large ribosomal subunit protein uL4A

1

3

High-throughput

0.437

High

645023

RL16A
Large ribosomal subunit protein uL13A

1

2

Small-scale

0.437

High

662151

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

700396

RSSA1
Small ribosomal subunit protein uS2A

1

2

High-throughput

0.437

High

706259

RS3A1
Small ribosomal subunit protein eS1A

1

1

High-throughput

0.437

High

754893

H3
Histone H3

1

2

High-throughput

0.437

High

754894

NUM1
Nuclear migration protein NUM1

1

1

High-throughput

0.437

High

754909

YM91
Putative methyltransferase YMR310C

1

1

High-throughput

0.437

High

754926

SGO1
Shugoshin

1

1

High-throughput

0.437

High

754928

RS10A
Small ribosomal subunit protein eS10A

1

1

High-throughput

0.437

High

406335

RL15A
Large ribosomal subunit protein eL15A

1

1

High-throughput

0.407

High

491141

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.407

High

667172

RL8B
Large ribosomal subunit protein eL8B

1

4

High-throughput

0.407

High

754879

RL4B
Large ribosomal subunit protein uL4B

1

3

High-throughput

0.407

High

754930

HSP33
Probable glutathione-independent glyoxalase HSP33

1

1

High-throughput

0.407

High

754932

HSP32
Probable glutathione-independent glyoxalase HSP32

1

1

High-throughput

0.407

High

754868

ULP2
Ubiquitin-like-specific protease 2

2

0

High-throughput

0.306

High

408351

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

2

0

High-throughput

0.305

High

743255

RL32
Large ribosomal subunit protein eL32

2

0

Small-scale

0.305

High

754895

RS15
Small ribosomal subunit protein uS19

2

0

High-throughput

0.305

High

754861

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

0

Small-scale

0.292

High

511225

SSB1
Ribosome-associated molecular chaperone SSB1

2

0

High-throughput

0.288

High

676032

XPO1
Exportin-1

1

0

High-throughput

0.279

Low

754887

COPA
Coatomer subunit alpha

1

0

High-throughput

0.269

Low

754890

RN35
Large ribosomal subunit protein bL35m

1

0

High-throughput

0.269

Low

754936

YRA1
RNA annealing protein YRA1

1

0

High-throughput

0.269

Low

357673

RL28
Large ribosomal subunit protein uL15

1

0

High-throughput

0.249

Low

358054

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.249

Low

471042

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.249

Low

471774

RL27A
Large ribosomal subunit protein eL27A

1

0

Small-scale

0.249

Low

481022

RL23B
Large ribosomal subunit protein uL14B

1

0

Small-scale

0.249

Low

628023

SIS1
Protein SIS1

1

0

High-throughput

0.249

Low

688228

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.249

Low

692780

SPT16
FACT complex subunit SPT16

1

0

High-throughput

0.249

Low

729900

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.249

Low

752437

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.249

Low

754361

RPP1
Ribonuclease P/MRP protein subunit RPP1

1

0

High-throughput

0.249

Low

754859

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

754869

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.249

Low

754877

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.249

Low

754878

RL38
Large ribosomal subunit protein eL38

1

0

Small-scale

0.249

Low

754882

EIF2A
Eukaryotic translation initiation factor 2A

1

0

High-throughput

0.249

Low

754892

APJ1
J domain-containing protein APJ1

1

0

High-throughput

0.249

Low

754901

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.249

Low

754911

HRQ1
ATP-dependent helicase HRQ1

1

0

Small-scale

0.249

Low

754913

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.249

Low

754919

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.249

Low

415968

DED1
ATP-dependent RNA helicase DED1

1

0

High-throughput

0.232

Low

421633

FAS1
Fatty acid synthase subunit beta

1

0

High-throughput

0.232

Low

478171

HSP77
Import motor subunit, mitochondrial

1

0

High-throughput

0.232

Low

605025

XRN1
5'-3' exoribonuclease 1

1

0

High-throughput

0.232

Low

633943

GBP2
Serine/arginine

1

0

High-throughput

0.232

Low

705146

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.232

Low

754875

TCPQ
T-complex protein 1 subunit theta

1

0

High-throughput

0.232

Low

754880

IMDH3
Inosine-5'-monophosphate dehydrogenase 3

1

0

High-throughput

0.232

Low

754939

JID1
J domain-containing protein 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024