Protein: DIM1
Dimethyladenosine transferase (EC 2.1.1.183) (18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase) (18S rRNA dimethylase) (S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase)

Gene: DIM1
Organism: Saccharomyces cerevisiae S288C
Interactions: 108
UniProt ID: P41819

Gene Ontology (top 5):
GO:0000154 - rRNA modification
GO:0000179 - rRNA (adenine-N6,N6-)-dimethyltransferase activity
GO:0000462 - maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0003723 - RNA binding
GO:0005730 - nucleolus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

770040

RIO2
Serine/threonine-protein kinase RIO2

13

2

Small-scale

0.757

High

748635

ENP1
Essential nuclear protein 1

11

2

Small-scale

0.754

High

784529

TSR1
Ribosome biogenesis protein TSR1

8

1

Small-scale

0.747

High

784525

DHR1
Probable ATP-dependent RNA helicase DHR1

4

1

Small-scale

0.676

High

784545

RRP12
Ribosomal RNA-processing protein 12

5

0

Small-scale

0.676

High

784533

NOB1
20S-pre-rRNA D-site endonuclease NOB1

5

0

Small-scale

0.673

High

784528

NOC4
Nucleolar complex protein 4

5

0

Small-scale

0.672

High

709372

LTV1
Protein LTV1

5

0

Small-scale

0.666

High

784547

PNO1
Pre-rRNA-processing protein PNO1

4

0

Small-scale

0.644

High

784526

UTP14
U3 small nucleolar RNA-associated protein 14

3

1

Small-scale

0.640

High

664484

HRR25
Casein kinase I homolog HRR25

3

0

Small-scale

0.638

High

784513

UTP22
U3 small nucleolar RNA-associated protein 22

3

0

High-throughput

0.634

High

635594

PWP2
Periodic tryptophan protein 2

3

0

High-throughput

0.628

High

784527

RRP9
Ribosomal RNA-processing protein 9

2

2

High-throughput

0.611

High

784512

SLX9
Ribosome biogenesis protein SLX9

3

0

Small-scale

0.606

High

784537

KAD6
Adenylate kinase isoenzyme 6 homolog FAP7

2

0

Small-scale

0.592

High

756746

UTP9
U3 small nucleolar RNA-associated protein 9

2

0

High-throughput

0.585

High

471114

RS22A
Small ribosomal subunit protein uS8A

2

1

High-throughput

0.571

High

480160

RS6A
Small ribosomal subunit protein eS6A

2

1

High-throughput

0.571

High

480729

RS8A
Small ribosomal subunit protein eS8A

2

1

High-throughput

0.571

High

631936

RS2
Small ribosomal subunit protein uS5

2

1

High-throughput

0.571

High

634656

KRR1
KRR1 small subunit processome component

2

0

High-throughput

0.559

High

784516

CSL4
Exosome complex component CSL4

2

0

High-throughput

0.559

High

784531

RCL1
RNA 3'-terminal phosphate cyclase-like protein

2

0

Small-scale

0.559

High

141387

RS9A
Small ribosomal subunit protein uS4A

2

0

High-throughput

0.547

High

407974

RS13
Small ribosomal subunit protein uS15

2

0

High-throughput

0.547

High

413567

RS14A
Small ribosomal subunit protein uS11A

2

0

High-throughput

0.547

High

645505

RS7A
Small ribosomal subunit protein eS7A

2

0

High-throughput

0.547

High

706332

RS3A1
Small ribosomal subunit protein eS1A

2

0

High-throughput

0.547

High

729965

RS27A
Small ribosomal subunit protein eS27A

2

0

High-throughput

0.547

High

746508

IMB2
Importin subunit beta-2

1

0

High-throughput

0.513

High

659798

SBA1
Co-chaperone protein SBA1

1

0

Small-scale

0.504

High

676135

XPO1
Exportin-1

1

1

High-throughput

0.489

High

383203

RL25
Large ribosomal subunit protein uL23

1

1

High-throughput

0.479

High

405680

RL26A
Large ribosomal subunit protein uL24A

1

2

High-throughput

0.479

High

426004

RS19A
Small ribosomal subunit protein eS19A

1

1

High-throughput

0.479

High

472246

RL31A
Large ribosomal subunit protein eL31A

1

1

High-throughput

0.479

High

742849

GBLP
Small ribosomal subunit protein RACK1

1

2

High-throughput

0.479

High

752510

RS20
Small ribosomal subunit protein uS10

1

1

High-throughput

0.479

High

784505

RRP41
Exosome complex component SKI6

1

1

High-throughput

0.479

High

784510

RS12
Small ribosomal subunit protein eS12

1

1

High-throughput

0.479

High

784514

RRP46
Exosome complex component RRP46

1

2

High-throughput

0.479

High

784523

UTP17
NET1-associated nuclear protein 1

1

2

High-throughput

0.479

High

784524

UTP5
U3 small nucleolar RNA-associated protein 5

1

1

High-throughput

0.479

High

784535

BMS1
Ribosome biogenesis protein BMS1

1

1

Small-scale

0.479

High

784542

RRP42
Exosome complex component RRP42

1

1

High-throughput

0.479

High

784543

NOP56
Nucleolar protein 56

1

1

High-throughput

0.479

High

784544

NOP58
Nucleolar protein 58

1

1

High-throughput

0.479

High

704788

SLA2
Protein SLA2

1

3

High-throughput

0.464

High

358118

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.458

High

407120

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

408391

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

0

High-throughput

0.458

High

482309

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.458

High

628178

SIS1
Protein SIS1

1

0

High-throughput

0.458

High

630211

RRP43
Exosome complex component RRP43

1

0

High-throughput

0.458

High

630501

RRP7
Ribosomal RNA-processing protein 7

1

0

High-throughput

0.458

High

700472

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.458

High

754966

RRP4
Exosome complex component RRP4

1

0

High-throughput

0.458

High

755175

LRP1
Exosome complex protein LRP1

1

0

High-throughput

0.458

High

762298

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.458

High

764973

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

0

High-throughput

0.458

High

768083

LCP5
U3 small nucleolar ribonucleoprotein protein LCP5

1

0

High-throughput

0.458

High

772635

UTP18
U3 small nucleolar RNA-associated protein 18

1

0

High-throughput

0.458

High

774717

UTP25
U3 small nucleolar RNA-associated protein 25

1

0

High-throughput

0.458

High

784504

UTP10
U3 small nucleolar RNA-associated protein 10

1

0

High-throughput

0.458

High

784506

MTR4
ATP-dependent RNA helicase DOB1

1

0

High-throughput

0.458

High

784507

NOP9
Nucleolar protein 9

1

0

Small-scale

0.458

High

784508

MPP10
U3 small nucleolar RNA-associated protein MPP10

1

0

Small-scale

0.458

High

784509

MTR3
Exosome complex component MTR3

1

0

High-throughput

0.458

High

784517

NAT10
RNA cytidine acetyltransferase

1

0

High-throughput

0.458

High

784518

NOP15
Ribosome biogenesis protein 15

1

0

High-throughput

0.458

High

784519

APJ1
J domain-containing protein APJ1

1

0

High-throughput

0.458

High

784520

IMP4
U3 small nucleolar ribonucleoprotein protein IMP4

1

0

Small-scale

0.458

High

784522

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

784532

RRP40
Exosome complex component RRP40

1

0

High-throughput

0.458

High

784534

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.458

High

784536

FCF2
rRNA-processing protein FCF2

1

0

High-throughput

0.458

High

784538

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.458

High

784539

SAS10
Something about silencing protein 10

1

0

Small-scale

0.458

High

784540

RRP6
Exosome complex exonuclease RRP6

1

0

High-throughput

0.458

High

784546

NOP14
Nucleolar complex protein 14

1

0

Small-scale

0.458

High

565651

PHO85
Cyclin-dependent protein kinase PHO85

1

1

High-throughput

0.457

High

481522

RS11B
Small ribosomal subunit protein uS17B

1

1

High-throughput

0.445

High

511685

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

768690

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

339692

CDK1
Cyclin-dependent kinase 1

1

1

High-throughput

0.437

High

650313

SPT5
Transcription elongation factor SPT5

1

1

High-throughput

0.437

High

368155

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.426

High

424571

PYR1
Multifunctional protein URA2

1

0

High-throughput

0.426

High

479354

RS23B
Small ribosomal subunit protein uS12B

1

0

High-throughput

0.426

High

479488

RS24A
Small ribosomal subunit protein eS24A

1

0

High-throughput

0.426

High

479611

RS30A
Small ribosomal subunit protein eS30A

1

0

High-throughput

0.426

High

479764

RS4A
Small ribosomal subunit protein eS4A

1

0

High-throughput

0.426

High

635428

BUD23
18S rRNA

1

0

High-throughput

0.426

High

556115

VATB
V-type proton ATPase subunit B

1

1

High-throughput

0.407

High

561002

EF3A
Elongation factor 3A

1

0

High-throughput

0.279

Low

524350

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.249

Low

527016

TBP
TATA-box-binding protein

1

0

High-throughput

0.249

Low

662508

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

688287

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.249

Low

745717

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

775746

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.249

Low

784511

EIF2A
Eukaryotic translation initiation factor 2A

1

0

High-throughput

0.249

Low

784515

GIS2
Zinc finger protein GIS2

1

0

High-throughput

0.249

Low

784521

H3
Histone H3

1

0

High-throughput

0.249

Low

784530

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.249

Low

784541

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.249

Low

340172

KPYK1
Pyruvate kinase 1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024