Protein: ARC1
tRNA-aminoacylation cofactor ARC1 (Acyl-RNA-complex protein 1) (GU4 nucleic-binding protein 1) (G4p1 protein) (P42) (tRNA-interacting factor ARC1)

Gene: ARC1
Organism: Saccharomyces cerevisiae S288C
Interactions: 116
UniProt ID: P46672

Gene Ontology (top 5):
GO:0000049 - tRNA binding
GO:0004831 - tyrosine-tRNA ligase activity
GO:0005737 - cytoplasm
GO:0006418 - tRNA aminoacylation for protein translation
GO:0006424 - glutamyl-tRNA aminoacylation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

343839

SYMC
Methionine--tRNA ligase, cytoplasmic

12

11

Small-scale

0.760

High

804881

SYEC
Glutamate--tRNA ligase, cytoplasmic

11

7

Small-scale

0.757

High

366502

HSP82
ATP-dependent molecular chaperone HSP82

5

3

Small-scale

0.699

High

543971

HSC82
ATP-dependent molecular chaperone HSC82

2

3

High-throughput

0.584

High

805068

MCA1
Metacaspase-1

2

0

High-throughput

0.576

High

748366

ATG12
Ubiquitin-like protein ATG12

1

1

High-throughput

0.536

High

746196

HEK2
Heterogeneous nuclear rnp K-like protein 2

1

1

High-throughput

0.515

High

746515

IMB2
Importin subunit beta-2

1

0

High-throughput

0.513

High

805059

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

0

High-throughput

0.513

High

539373

KSS1
Mitogen-activated protein kinase KSS1

1

1

High-throughput

0.501

High

565669

PHO85
Cyclin-dependent protein kinase PHO85

1

1

High-throughput

0.501

High

607862

SYMM
Methionine--tRNA ligase, mitochondrial

1

11

Small-scale

0.501

High

614989

KC12
Casein kinase I homolog 2

1

1

High-throughput

0.501

High

701896

SWE1
Mitosis inhibitor protein kinase SWE1

1

1

High-throughput

0.501

High

730483

NNK1
Nitrogen network kinase 1

1

1

High-throughput

0.501

High

758795

IPL1
Spindle assembly checkpoint kinase

1

2

High-throughput

0.501

High

805045

PTK2
Serine/threonine-protein kinase PTK2/STK2

1

4

High-throughput

0.501

High

805062

SKY1
Serine/threonine-protein kinase SKY1

1

4

High-throughput

0.501

High

805073

SKM1
Serine/threonine-protein kinase SKM1

1

2

High-throughput

0.501

High

472649

YH41B
Transposon Ty4-H Gag-Pol polyprotein

1

0

High-throughput

0.493

High

523412

SRS2
ATP-dependent DNA helicase SRS2

1

0

High-throughput

0.493

High

755999

YHT1
PH domain-containing protein YHR131C

1

0

High-throughput

0.493

High

761599

CAT8
Regulatory protein CAT8

1

0

High-throughput

0.493

High

805054

CTU2
Cytoplasmic tRNA 2-thiolation protein 2

1

0

High-throughput

0.493

High

805056

HDA1
Histone deacetylase HDA1

1

0

High-throughput

0.493

High

805071

RTK1
Probable serine/threonine-protein kinase RTK1

1

2

High-throughput

0.489

High

691203

MKK1
MAP kinase kinase MKK1/SSP32

1

2

High-throughput

0.481

High

412797

KAPA
cAMP-dependent protein kinase type 1

1

0

High-throughput

0.480

High

606052

RAD53
Serine/threonine-protein kinase RAD53

1

0

High-throughput

0.480

High

648196

KCC1
Calcium/calmodulin-dependent protein kinase I

1

0

High-throughput

0.480

High

710973

HSL1
Probable serine/threonine-protein kinase HSL1

1

0

High-throughput

0.480

High

743892

AKL1
Serine/threonine-protein kinase AKL1

1

0

High-throughput

0.480

High

752149

KSP1
Serine/threonine-protein kinase KSP1

1

0

High-throughput

0.480

High

805046

BPL1
Biotin--protein ligase

1

0

Small-scale

0.480

High

805049

ATG1
Serine/threonine-protein kinase ATG1

1

0

High-throughput

0.480

High

805058

BCK1
Serine/threonine-protein kinase BCK1/SLK1/SSP31

1

0

High-throughput

0.480

High

389110

SYDC
Aspartate--tRNA ligase, cytoplasmic

1

6

High-throughput

0.479

High

407143

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.479

High

450322

SYIC
Isoleucine--tRNA ligase, cytoplasmic

1

7

Small-scale

0.479

High

482324

RS18A
Small ribosomal subunit protein uS13A

1

1

High-throughput

0.479

High

546191

SYKC
Lysine--tRNA ligase, cytoplasmic

1

6

High-throughput

0.479

High

631952

RS2
Small ribosomal subunit protein uS5

1

1

High-throughput

0.479

High

643679

SYLC
Leucine--tRNA ligase, cytoplasmic

1

8

High-throughput

0.479

High

664915

BMH1
Protein BMH1

1

1

High-throughput

0.479

High

680817

HS104
Heat shock protein 104

1

1

High-throughput

0.479

High

700488

RSSA1
Small ribosomal subunit protein uS2A

1

2

High-throughput

0.479

High

734842

SYYC
Tyrosine--tRNA ligase, cytoplasmic

1

1

High-throughput

0.479

High

742864

GBLP
Small ribosomal subunit protein RACK1

1

3

High-throughput

0.479

High

752849

SYNC
Asparagine--tRNA ligase, cytoplasmic

1

5

High-throughput

0.479

High

752929

YHI0
Putative proline--tRNA ligase YHR020W

1

4

High-throughput

0.479

High

805061

TOM1
E3 ubiquitin-protein ligase TOM1

1

2

High-throughput

0.479

High

687417

EF2
Elongation factor 2

1

2

High-throughput

0.470

High

805067

IRC20
Uncharacterized ATP-dependent helicase IRC20

1

1

High-throughput

0.470

High

141401

RS9A
Small ribosomal subunit protein uS4A

1

0

High-throughput

0.458

High

407987

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.458

High

524364

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.458

High

692555

ZUO1
Zuotin

1

0

High-throughput

0.458

High

729979

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.458

High

752526

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.458

High

764919

SS120
Protein SSP120

1

0

High-throughput

0.458

High

764981

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

0

High-throughput

0.458

High

805047

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

805051

EIF2A
Eukaryotic translation initiation factor 2A

1

0

High-throughput

0.458

High

805052

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

High-throughput

0.458

High

805060

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

605555

DBF2
Cell cycle protein kinase DBF2

1

1

High-throughput

0.457

High

614708

KC11
Casein kinase I homolog 1

1

1

High-throughput

0.457

High

758567

HAL5
Serine/threonine-protein kinase HAL5

1

2

High-throughput

0.457

High

768766

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

413584

RS14A
Small ribosomal subunit protein uS11A

1

1

High-throughput

0.437

High

472261

RL31A
Large ribosomal subunit protein eL31A

1

1

High-throughput

0.437

High

480175

RS6A
Small ribosomal subunit protein eS6A

1

1

High-throughput

0.437

High

805070

AP3D
AP-3 complex subunit delta

1

1

High-throughput

0.437

High

748453

CLPX
ATP-dependent clpX-like chaperone, mitochondrial

1

1

High-throughput

0.407

High

710681

PXA2
Peroxisomal long-chain fatty acid import protein 1

1

0

High-throughput

0.282

High

761533

YCFI
Metal resistance protein YCF1

1

0

High-throughput

0.282

High

420443

RAD10
DNA repair protein RAD10

1

0

High-throughput

0.279

Low

629571

CDC10
Cell division control protein 10

1

0

High-throughput

0.279

Low

715348

SPT7
Transcriptional activator SPT7

1

0

High-throughput

0.279

Low

805064

SEN15
tRNA-splicing endonuclease subunit SEN15

1

0

High-throughput

0.279

Low

648993

PHO91
Low-affinity phosphate transporter PHO91

1

0

High-throughput

0.269

Low

696696

PT127
Putative mitochondrial translation system component PET127

1

0

High-throughput

0.269

Low

728423

YKF0
Uncharacterized protein YKL050C

1

0

High-throughput

0.269

Low

747585

ATG14
Autophagy-related protein 14

1

0

High-throughput

0.269

Low

749128

PHO89
Phosphate permease PHO89

1

0

High-throughput

0.269

Low

758897

ATU2
Copper-transporting ATPase

1

0

High-throughput

0.269

Low

768330

COG3
Conserved oligomeric Golgi complex subunit 3

1

0

High-throughput

0.269

Low

775972

MGA2
Protein MGA2

1

0

High-throughput

0.269

Low

805075

NAH1

1

0

High-throughput

0.269

Low

805050

PDK2
[Pyruvate dehydrogenase

1

0

High-throughput

0.261

Low

775200

ULP2
Ubiquitin-like-specific protease 2

1

0

High-throughput

0.251

Low

358134

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.249

Low

383217

RL25
Large ribosomal subunit protein uL23

1

0

High-throughput

0.249

Low

405692

RL26A
Large ribosomal subunit protein uL24A

1

0

High-throughput

0.249

Low

426019

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.249

Low

471128

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.249

Low

480746

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.249

Low

628209

SIS1
Protein SIS1

1

0

High-throughput

0.249

Low

638796

SPB4
ATP-dependent rRNA helicase SPB4

1

0

High-throughput

0.249

Low

645519

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.249

Low

662588

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

706347

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.249

Low

762329

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

775761

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.249

Low

797023

EMP47
Protein EMP47

1

0

High-throughput

0.249

Low

805048

VATG
V-type proton ATPase subunit G

1

0

High-throughput

0.249

Low

805053

H1
Histone H1

1

0

High-throughput

0.249

Low

805055

SAM50
Sorting assembly machinery 50 kDa subunit

1

0

High-throughput

0.249

Low

805057

H3
Histone H3

1

0

High-throughput

0.249

Low

805063

RUVB1
RuvB-like protein 1

1

0

High-throughput

0.249

Low

805065

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.249

Low

805066

SEC10
Exocyst complex component SEC10

1

0

Small-scale

0.249

Low

805069

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.249

Low

805072

RRP6
Exosome complex exonuclease RRP6

1

0

High-throughput

0.249

Low

805074

SMC6
Structural maintenance of chromosomes protein 6

1

0

High-throughput

0.249

Low

757433

SPT8
Transcription factor SPT8

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024