Protein: ITA2B
Integrin alpha-IIb (GPalpha IIb) (GPIIb) (Platelet membrane glycoprotein IIb) (CD antigen CD41) [Cleaved into: Integrin alpha-IIb heavy chain; Integrin alpha-IIb light chain]

Gene: ITA2B, Itga2b
Organism: Mus musculus
Interactions: 149
UniProt ID: Q9QUM0

Gene Ontology (top 5):
GO:0002687 - positive regulation of leukocyte migration
GO:0005925 - focal adhesion
GO:0007160 - cell-matrix adhesion
GO:0007229 - integrin-mediated signaling pathway
GO:0009897 - external side of plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1455802

ITA2B
Integrin alpha-IIb

1

3

High-throughput

0.647

High

204800

PLD3
5'-3' exonuclease PLD3

1

3

High-throughput

0.501

High

464499

PDIA4
Protein disulfide-isomerase A4

1

3

High-throughput

0.501

High

553504

PFKAL
ATP-dependent 6-phosphofructokinase, liver type

1

2

High-throughput

0.501

High

602942

ENOA
Alpha-enolase

1

2

High-throughput

0.501

High

837999

SEPT2
Septin-2

1

4

High-throughput

0.501

High

940870

ATPB
ATP synthase F(1) complex catalytic subunit beta, mitochondrial

1

2

High-throughput

0.501

High

989466

CH60
60 kDa heat shock protein, mitochondrial

1

7

High-throughput

0.501

High

989589

MK01
Mitogen-activated protein kinase 1

1

3

High-throughput

0.501

High

993117

ACTG
Actin, cytoplasmic 2

1

3

High-throughput

0.501

High

997607

TBB4B
Tubulin beta-4B chain

1

6

High-throughput

0.501

High

1023490

TBB5
Tubulin beta-5 chain

1

6

High-throughput

0.501

High

1189398

PDE12
2',5'-phosphodiesterase 12

1

1

High-throughput

0.501

High

1298718

PDLI5
PDZ and LIM domain protein 5

1

12

High-throughput

0.501

High

1362908

Q921W7
Testin

1

11

High-throughput

0.501

High

1408914

LPXN
Leupaxin

1

10

High-throughput

0.501

High

1424013

ERP44
Endoplasmic reticulum resident protein 44

1

4

High-throughput

0.501

High

481011

PGK1
Phosphoglycerate kinase 1

1

0

High-throughput

0.480

High

664242

CATA
Catalase

1

0

High-throughput

0.480

High

665770

IMDH2
Inosine-5'-monophosphate dehydrogenase 2

1

0

High-throughput

0.480

High

945747

NADK
NAD kinase

1

0

High-throughput

0.480

High

1297381

GMPPB
Mannose-1-phosphate guanylyltransferase catalytic subunit beta

1

0

High-throughput

0.480

High

1297508

OSGEP
tRNA N6-adenosine threonylcarbamoyltransferase

1

0

High-throughput

0.480

High

1297641

LACC1
Purine nucleoside phosphorylase LACC1

1

0

High-throughput

0.480

High

1317167

NAGA
N-acetylglucosamine-6-phosphate deacetylase

1

0

High-throughput

0.480

High

1423818

ARPC2
Actin-related protein 2/3 complex subunit 2

1

0

High-throughput

0.480

High

1423997

CNDP2
Cytosolic non-specific dipeptidase

1

0

High-throughput

0.480

High

1424169

MGDP1
Magnesium-dependent phosphatase 1

1

0

High-throughput

0.480

High

147586

DPYL2
Dihydropyrimidinase-related protein 2

1

1

High-throughput

0.457

High

147612

LEG9
Galectin-9

1

20

High-throughput

0.457

High

148350

PRDX4
Peroxiredoxin-4

1

4

High-throughput

0.457

High

205305

ANXA3
Annexin A3

1

2

High-throughput

0.457

High

205538

HNRH1
Heterogeneous nuclear ribonucleoprotein H

1

8

High-throughput

0.457

High

237191

SEPT7
Septin-7

1

4

High-throughput

0.457

High

312104

WDR1
WD repeat-containing protein 1

1

1

High-throughput

0.457

High

312389

DC1I2
Cytoplasmic dynein 1 intermediate chain 2

1

1

High-throughput

0.457

High

313364

COR1A
Coronin-1A

1

2

High-throughput

0.457

High

367629

CAH2
Carbonic anhydrase 2

1

6

High-throughput

0.457

High

421214

ALDOC
Fructose-bisphosphate aldolase C

1

2

High-throughput

0.457

High

421239

ALDOA
Fructose-bisphosphate aldolase A

1

2

High-throughput

0.457

High

439050

LDHA
L-lactate dehydrogenase A chain

1

5

High-throughput

0.457

High

469646

MDHM
Malate dehydrogenase, mitochondrial

1

5

High-throughput

0.457

High

518703

EF1A1
Elongation factor 1-alpha 1

1

1

High-throughput

0.457

High

571111

RSSA
Small ribosomal subunit protein uS2

1

1

High-throughput

0.457

High

574844

PSMD3
26S proteasome non-ATPase regulatory subunit 3

1

1

High-throughput

0.457

High

576871

RLA0
Large ribosomal subunit protein uL10

1

2

High-throughput

0.457

High

591979

LDHB
L-lactate dehydrogenase B chain

1

5

High-throughput

0.457

High

598348

HS71L
Heat shock 70 kDa protein 1-like

1

3

High-throughput

0.457

High

628524

VIME
Vimentin

1

3

High-throughput

0.457

High

685806

U2AF2
Splicing factor U2AF 65 kDa subunit

1

6

High-throughput

0.457

High

694451

H2AX
Histone H2AX

1

5

High-throughput

0.457

High

711235

PTN6
Tyrosine-protein phosphatase non-receptor type 6

1

10

High-throughput

0.457

High

732111

LA
Lupus La protein homolog

1

5

High-throughput

0.457

High

772451

CALX
Calnexin

1

10

High-throughput

0.457

High

776021

PRDX1
Peroxiredoxin-1

1

5

High-throughput

0.457

High

801656

HSPA9
Stress-70 protein, mitochondrial

1

7

High-throughput

0.457

High

822493

VP26A
Vacuolar protein sorting-associated protein 26A

1

1

High-throughput

0.457

High

844317

TCPQ
T-complex protein 1 subunit theta

1

9

High-throughput

0.457

High

868847

CRKL
Crk-like protein

1

5

High-throughput

0.457

High

886369

HCLS1
Hematopoietic lineage cell-specific protein

1

2

High-throughput

0.457

High

908596

ADT2
ADP/ATP translocase 2

1

2

High-throughput

0.457

High

912313

KPYM
Pyruvate kinase PKM

1

1

High-throughput

0.457

High

932539

PUR8
Adenylosuccinate lyase

1

1

High-throughput

0.457

High

949841

PCBP1
Poly(rC)-binding protein 1

1

9

High-throughput

0.457

High

966111

HNRPK
Heterogeneous nuclear ribonucleoprotein K

1

10

High-throughput

0.457

High

972323

1433E
14-3-3 protein epsilon

1

1

High-throughput

0.457

High

974511

SMD1
Small nuclear ribonucleoprotein Sm D1

1

4

High-throughput

0.457

High

980676

H4
Histone H4

1

1

High-throughput

0.457

High

981426

RAB1A
Ras-related protein Rab-1A

1

2

High-throughput

0.457

High

990060

1433Z
14-3-3 protein zeta/delta

1

6

High-throughput

0.457

High

1000047

EM55
55 kDa erythrocyte membrane protein

1

1

High-throughput

0.457

High

1000322

ELAV1
ELAV-like protein 1

1

3

High-throughput

0.457

High

1000434

NHRF1
Na(+)/H(+) exchange regulatory cofactor NHE-RF1

1

2

High-throughput

0.457

High

1009931

TCPH
T-complex protein 1 subunit eta

1

7

High-throughput

0.457

High

1009948

TCPB
T-complex protein 1 subunit beta

1

7

High-throughput

0.457

High

1009963

TCPD
T-complex protein 1 subunit delta

1

7

High-throughput

0.457

High

1021998

G3BP1
Ras GTPase-activating protein-binding protein 1

1

1

High-throughput

0.457

High

1030288

SC23A
Protein transport protein Sec23A

1

2

High-throughput

0.457

High

1046687

KCRB
Creatine kinase B-type

1

1

High-throughput

0.457

High

1189384

GUAA
GMP synthase [glutamine-hydrolyzing]

1

2

High-throughput

0.457

High

1190121

SNX27
Sorting nexin-27

1

1

High-throughput

0.457

High

1190937

K22O
Keratin, type II cytoskeletal 2 oral

1

3

High-throughput

0.457

High

1222179

ASNS
Asparagine synthetase [glutamine-hydrolyzing]

1

1

High-throughput

0.457

High

1222473

PA1B2
Platelet-activating factor acetylhydrolase IB subunit alpha2

1

1

High-throughput

0.457

High

1223261

HS71A
Heat shock 70 kDa protein 1A

1

3

High-throughput

0.457

High

1223313

SERA
D-3-phosphoglycerate dehydrogenase

1

1

High-throughput

0.457

High

1238937

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

6

High-throughput

0.457

High

1257516

H2B1C
Histone H2B type 1-C/E/G

1

7

High-throughput

0.457

High

1295905

PLD4
5'-3' exonuclease PLD4

1

3

High-throughput

0.457

High

1297121

SYNC
Asparagine--tRNA ligase, cytoplasmic

1

4

High-throughput

0.457

High

1297367

Q8BTS0
Probable ATP-dependent RNA helicase DDX5

1

6

High-throughput

0.457

High

1297997

SEP11
Septin-11

1

4

High-throughput

0.457

High

1317183

EIPR1
EARP and GARP complex-interacting protein 1

1

2

High-throughput

0.457

High

1341448

HNRPL
Heterogeneous nuclear ribonucleoprotein L

1

8

High-throughput

0.457

High

1362392

ARLY
Argininosuccinate lyase

1

1

High-throughput

0.457

High

1362415

TWF1
Twinfilin-1

1

3

High-throughput

0.457

High

1362867

HNRLL
Heterogeneous nuclear ribonucleoprotein L-like

1

7

High-throughput

0.457

High

1363021

BLVRB
Flavin reductase

1

1

High-throughput

0.457

High

1408756

ARP3
Actin-related protein 3

1

4

High-throughput

0.457

High

1408877

ARBK1
Beta-adrenergic receptor kinase 1

1

3

High-throughput

0.457

High

1423644

MTAP
S-methyl-5'-thioadenosine phosphorylase

1

1

High-throughput

0.457

High

1423739

MTNA
Methylthioribose-1-phosphate isomerase

1

1

High-throughput

0.457

High

1424046

MLKL
Mixed lineage kinase domain-like protein

1

5

High-throughput

0.457

High

1424096

SC23B
Protein transport protein Sec23B

1

2

High-throughput

0.457

High

1424114

GLGB
1,4-alpha-glucan-branching enzyme

1

2

High-throughput

0.457

High

1424372

VPS35
Vacuolar protein sorting-associated protein 35

1

1

High-throughput

0.457

High

1424450

SDF2L
Stromal cell-derived factor 2-like protein 1

1

1

High-throughput

0.457

High

1440936

ARPC3
Actin-related protein 2/3 complex subunit 3

1

1

High-throughput

0.457

High

1440938

STAP1
Signal-transducing adaptor protein 1

1

1

High-throughput

0.457

High

1455803

ZBP1
Z-DNA-binding protein 1

1

1

High-throughput

0.457

High

1455806

COR1B
Coronin-1B

1

2

High-throughput

0.457

High

1455807

COR1C
Coronin-1C

1

3

High-throughput

0.457

High

1455808

ARC1B
Actin-related protein 2/3 complex subunit 1B

1

2

High-throughput

0.457

High

1455809

TWF2
Twinfilin-2

1

3

High-throughput

0.457

High

1455810

STRAP
Serine-threonine kinase receptor-associated protein

1

2

High-throughput

0.457

High

1341650

CRAC1
Cartilage acidic protein 1

1

2

Small-scale

0.407

High

266866

NMT1
Glycylpeptide N-tetradecanoyltransferase 1

1

0

High-throughput

0.261

Low

312774

CREG1
Protein CREG1

1

0

High-throughput

0.261

Low

313288

LGMN
Legumain

1

0

High-throughput

0.261

Low

361948

HPRT
Hypoxanthine-guanine phosphoribosyltransferase

1

0

High-throughput

0.261

Low

446497

G6PI
Glucose-6-phosphate isomerase

1

0

High-throughput

0.261

Low

584831

NDKA
Nucleoside diphosphate kinase A

1

0

High-throughput

0.261

Low

607889

TPIS
Triosephosphate isomerase

1

0

High-throughput

0.261

Low

686778

DHE3
Glutamate dehydrogenase 1, mitochondrial

1

0

High-throughput

0.261

Low

712472

HEXA
Beta-hexosaminidase subunit alpha

1

0

High-throughput

0.261

Low

818824

CAP1
Adenylyl cyclase-associated protein 1

1

0

High-throughput

0.261

Low

818872

TKT
Transketolase

1

0

High-throughput

0.261

Low

992679

IF5A1
Eukaryotic translation initiation factor 5A-1

1

0

High-throughput

0.261

Low

1021769

GSH1
Glutamate--cysteine ligase catalytic subunit

1

0

High-throughput

0.261

Low

1021951

CATC
Dipeptidyl peptidase 1

1

0

High-throughput

0.261

Low

1026314

G6PD1
Glucose-6-phosphate 1-dehydrogenase X

1

0

High-throughput

0.261

Low

1222755

HCDH
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial

1

0

High-throughput

0.261

Low

1283510

CCD50
Coiled-coil domain-containing protein 50

1

0

High-throughput

0.261

Low

1296518

Q8BGZ6
Alpha-galactosidase

1

0

High-throughput

0.261

Low

1317214

PDXK
Pyridoxal kinase

1

0

High-throughput

0.261

Low

1362395

ARRB2
Beta-arrestin-2

1

0

High-throughput

0.261

Low

1408768

RRAGC
Ras-related GTP-binding protein C

1

0

High-throughput

0.261

Low

1408817

MAT2B
Methionine adenosyltransferase 2 subunit beta

1

0

High-throughput

0.261

Low

1423622

ARPC5
Actin-related protein 2/3 complex subunit 5

1

0

High-throughput

0.261

Low

1423979

MCES
mRNA cap guanine-N(7) methyltransferase

1

0

High-throughput

0.261

Low

1424008

ADSSP
Adipose-secreted signaling protein

1

0

High-throughput

0.261

Low

1424140

U2AF1
Splicing factor U2AF 35 kDa subunit

1

0

High-throughput

0.261

Low

1424204

PGAM1
Phosphoglycerate mutase 1

1

0

High-throughput

0.261

Low

1424389

SET
Protein SET

1

0

High-throughput

0.261

Low

1455804

DNJA2
DnaJ homolog subfamily A member 2

1

0

High-throughput

0.261

Low

1455805

NAGK
N-acetyl-D-glucosamine kinase

1

0

High-throughput

0.261

Low

1455811

MTM1
Myotubularin

1

0

High-throughput

0.261

Low

644454

TAL1
T-cell acute lymphocytic leukemia protein 1 homolog

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025