Protein: SF3B1
U2 snRNP component HSH155

Gene: SF3B1, HSH155
Organism: Saccharomyces cerevisiae S288C
Interactions: 108
UniProt ID: P49955

Gene Ontology (top 5):
GO:0000245 - spliceosomal complex assembly
GO:0000398 - mRNA splicing, via spliceosome
GO:0003729 - mRNA binding
GO:0005634 - nucleus
GO:0005681 - spliceosomal complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

836926

CUS1
Cold sensitive U2 snRNA suppressor 1

9

2

Small-scale

0.752

High

836936

RSE1
Pre-mRNA-splicing factor RSE1

6

6

Small-scale

0.734

High

836946

RU2A
U2 small nuclear ribonucleoprotein A'

6

12

Small-scale

0.729

High

598577

PRP5
Pre-mRNA-processing ATP-dependent RNA helicase PRP5

5

8

Small-scale

0.715

High

836918

CUS2
Cold sensitive U2 snRNA suppressor 2

5

15

Small-scale

0.714

High

836931

CEF1
Pre-mRNA-splicing factor CEF1

4

7

High-throughput

0.699

High

692318

PRP19
Pre-mRNA-processing factor 19

4

20

Small-scale

0.691

High

766921

RSMB
Small nuclear ribonucleoprotein-associated protein B

4

3

High-throughput

0.686

High

836941

RDS3
Pre-mRNA-splicing factor RDS3

4

1

Small-scale

0.686

High

836950

CLF1
Pre-mRNA-splicing factor CLF1

4

12

Small-scale

0.682

High

655725

PRP45
Pre-mRNA-processing protein 45

3

6

High-throughput

0.662

High

697227

BRR2
Pre-mRNA-splicing helicase BRR2

3

12

Small-scale

0.656

High

469789

YSF3
RDS3 complex subunit 10

4

0

Small-scale

0.653

High

836942

PRP11
Pre-mRNA-splicing factor PRP11

3

1

High-throughput

0.650

High

770316

RUXG
Small nuclear ribonucleoprotein G

3

6

High-throughput

0.643

High

836920

RUXF
Small nuclear ribonucleoprotein F

3

2

High-throughput

0.643

High

589437

PRP2
Pre-mRNA-splicing factor ATP-dependent RNA helicase-like protein PRP2

3

6

Small-scale

0.642

High

809537

CWC26
Pre-mRNA-splicing factor CWC26

3

1

Small-scale

0.637

High

836943

LUC7
Protein LUC7

2

2

High-throughput

0.621

High

692409

PRP21
Pre-mRNA-splicing factor PRP21

2

2

High-throughput

0.611

High

836917

CWC22
Pre-mRNA-splicing factor CWC22

2

1

High-throughput

0.611

High

836922

H3
Histone H3

2

6

High-throughput

0.601

High

747715

SP381
Pre-mRNA-splicing factor SPP381

2

0

High-throughput

0.595

High

836951

RUXE
Small nuclear ribonucleoprotein E

2

2

High-throughput

0.588

High

836929

PRP3
U4/U6 small nuclear ribonucleoprotein PRP3

2

1

Small-scale

0.586

High

836945

NCBP2
Nuclear cap-binding protein subunit 2

2

10

High-throughput

0.584

High

836954

HSH49
Protein HSH49

2

9

Small-scale

0.584

High

836947

CWC2
Pre-mRNA-splicing factor CWC2

2

6

High-throughput

0.571

High

732373

MUD2
Splicing factor MUD2

2

0

Small-scale

0.570

High

558146

RPB3
DNA-directed RNA polymerase II subunit RPB3

2

0

Small-scale

0.559

High

511952

SSB1
Ribosome-associated molecular chaperone SSB1

1

11

High-throughput

0.536

High

676200

XPO1
Exportin-1

1

6

High-throughput

0.536

High

767795

LSM4
U6 snRNA-associated Sm-like protein LSm4

1

3

High-throughput

0.536

High

775697

IST3
U2 snRNP component IST3

1

10

Small-scale

0.536

High

836940

URN1
Pre-mRNA-splicing factor URN1

1

0

High-throughput

0.513

High

635886

PAT1
Deadenylation-dependent mRNA-decapping factor PAT1

1

2

High-throughput

0.508

High

614723

KC11
Casein kinase I homolog 1

1

12

High-throughput

0.501

High

811875

PTK2
Serine/threonine-protein kinase PTK2/STK2

1

11

High-throughput

0.501

High

836915

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

1

5

Small-scale

0.481

High

836927

RPM2
Ribonuclease P protein component, mitochondrial

1

0

Small-scale

0.480

High

407181

RS3
Small ribosomal subunit protein uS3

1

3

High-throughput

0.479

High

413608

RS14A
Small ribosomal subunit protein uS11A

1

1

High-throughput

0.479

High

586424

PRP6
Pre-mRNA-splicing factor 6

1

10

High-throughput

0.479

High

586502

PRP9
Pre-mRNA-splicing factor PRP9

1

2

High-throughput

0.479

High

636673

CDC48
Cell division control protein 48

1

4

Small-scale

0.479

High

662736

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.479

High

694119

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

9

High-throughput

0.479

High

704687

PRP8
Pre-mRNA-splicing factor 8

1

2

High-throughput

0.479

High

710187

NCBP1
Nuclear cap-binding protein complex subunit 1

1

5

High-throughput

0.479

High

731742

SN114
Pre-mRNA-splicing factor SNU114

1

9

High-throughput

0.479

High

746863

SLT11
Pre-mRNA-splicing factor SLT11

1

1

High-throughput

0.479

High

752555

RS20
Small ribosomal subunit protein uS10

1

2

High-throughput

0.479

High

778622

PRP17
Pre-mRNA-processing factor 17

1

14

High-throughput

0.479

High

795396

SMD3
Small nuclear ribonucleoprotein Sm D3

1

7

High-throughput

0.479

High

830815

PRP31
Pre-mRNA-processing factor 31

1

4

High-throughput

0.479

High

836923

NAM8
Protein NAM8

1

6

High-throughput

0.479

High

836925

SMD1
Small nuclear ribonucleoprotein Sm D1

1

2

High-throughput

0.479

High

836930

CWC21
Pre-mRNA-splicing factor CWC21

1

1

High-throughput

0.479

High

836934

SCC2
Sister chromatid cohesion protein 2

1

2

High-throughput

0.479

High

836935

SYF1
Pre-mRNA-splicing factor SYF1

1

9

High-throughput

0.479

High

836939

SMD2
Small nuclear ribonucleoprotein Sm D2

1

2

High-throughput

0.479

High

836948

SCC1
Sister chromatid cohesion protein 1

1

1

High-throughput

0.479

High

836949

BBP
Branchpoint-bridging protein

1

4

High-throughput

0.479

High

836952

PRP46
Pre-mRNA-splicing factor PRP46

1

15

High-throughput

0.479

High

836953

SNU66
66 kDa U4/U6.U5 small nuclear ribonucleoprotein component

1

1

Small-scale

0.479

High

836928

SLU7
Pre-mRNA-splicing factor SLU7

1

0

Small-scale

0.460

High

598634

ISY1
Pre-mRNA-splicing factor ISY1

1

0

High-throughput

0.458

High

629381

BUD31
Pre-mRNA-splicing factor BUD31

1

0

High-throughput

0.458

High

657747

YJU2
Splicing factor YJU2

1

0

High-throughput

0.458

High

696645

RU1A
U1 small nuclear ribonucleoprotein A

1

0

High-throughput

0.458

High

733079

NTR2
Pre-mRNA-splicing factor NTR2

1

0

High-throughput

0.458

High

748074

NTC20
Pre-mRNA-splicing factor NTC20

1

0

High-throughput

0.458

High

836916

SYF2
Pre-mRNA-splicing factor SYF2

1

0

High-throughput

0.458

High

836919

CWC25
Pre-mRNA-splicing factor CWC25

1

0

High-throughput

0.458

High

836933

CWC15
Pre-mRNA-splicing factor CWC15

1

0

High-throughput

0.458

High

836937

RU1C
U1 small nuclear ribonucleoprotein C

1

0

High-throughput

0.458

High

836938

SN309
Pre-mRNA-splicing factor SNT309

1

0

High-throughput

0.458

High

836914

ATG1
Serine/threonine-protein kinase ATG1

1

17

High-throughput

0.457

High

366577

HSP82
ATP-dependent molecular chaperone HSP82

1

9

High-throughput

0.445

High

491791

HSP71
Heat shock protein SSA1

1

10

High-throughput

0.445

High

494410

HSP72
Heat shock protein SSA2

1

10

High-throughput

0.445

High

695068

HSP7F
Heat shock protein homolog SSE1

1

16

High-throughput

0.445

High

696014

HSP79
Heat shock protein homolog SSE2

1

15

High-throughput

0.445

High

768898

SSB2
Ribosome-associated molecular chaperone SSB2

1

11

High-throughput

0.445

High

836921

LSM3
U6 snRNA-associated Sm-like protein LSm3

1

9

High-throughput

0.445

High

141426

RS9A
Small ribosomal subunit protein uS4A

1

2

High-throughput

0.437

High

383242

RL25
Large ribosomal subunit protein uL23

1

6

High-throughput

0.437

High

405718

RL26A
Large ribosomal subunit protein uL24A

1

5

High-throughput

0.437

High

408010

RS13
Small ribosomal subunit protein uS15

1

2

High-throughput

0.437

High

426045

RS19A
Small ribosomal subunit protein eS19A

1

3

High-throughput

0.437

High

471151

RS22A
Small ribosomal subunit protein uS8A

1

1

High-throughput

0.437

High

472290

RL31A
Large ribosomal subunit protein eL31A

1

3

High-throughput

0.437

High

480203

RS6A
Small ribosomal subunit protein eS6A

1

5

High-throughput

0.437

High

482350

RS18A
Small ribosomal subunit protein uS13A

1

1

High-throughput

0.437

High

645542

RS7A
Small ribosomal subunit protein eS7A

1

2

High-throughput

0.437

High

700515

RSSA1
Small ribosomal subunit protein uS2A

1

7

High-throughput

0.437

High

730012

RS27A
Small ribosomal subunit protein eS27A

1

1

High-throughput

0.437

High

731123

LHS1
Heat shock protein 70 homolog LHS1

1

11

High-throughput

0.437

High

760772

TCPG
T-complex protein 1 subunit gamma

1

2

High-throughput

0.437

High

836924

RS15
Small ribosomal subunit protein uS19

1

1

High-throughput

0.437

High

836944

RS10A
Small ribosomal subunit protein eS10A

1

2

High-throughput

0.437

High

705409

HSP78
Heat shock protein 78, mitochondrial

1

2

High-throughput

0.407

High

766102

HSP7E
Heat shock protein SSC3, mitochondrial

1

11

High-throughput

0.407

High

810059

PFD1
Prefoldin subunit 1

1

1

High-throughput

0.407

High

748157

AIM4
Altered inheritance of mitochondria protein 4

1

0

High-throughput

0.249

Low

762373

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

820061

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.249

Low

836932

PML39
Pre-mRNA leakage protein 39

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024