Protein: RCM1
25S rRNA (cytosine(2278)-C(5))-methyltransferase (EC 2.1.1.311) (rRNA m(5)C methyltransferase 1)

Gene: RCM1
Organism: Saccharomyces cerevisiae S288C
Interactions: 76
UniProt ID: P53972

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005730 - nucleolus
GO:0009383 - rRNA (cytosine-C5-)-methyltransferase activity
GO:0070475 - rRNA base methylation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

778834

NOP2
25S rRNA

1

4

High-throughput

0.618

High

866867

NIP7
60S ribosome subunit biogenesis protein NIP7

1

2

High-throughput

0.618

High

859491

NSA1
Ribosome biogenesis protein NSA1

2

1

High-throughput

0.584

High

860855

PESC
Pescadillo homolog

2

2

High-throughput

0.584

High

733894

RPF2
Ribosome biogenesis protein RPF2

2

2

High-throughput

0.571

High

676277

XPO1
Exportin-1

1

1

High-throughput

0.536

High

707306

RT05
Small ribosomal subunit protein uS5m

1

3

High-throughput

0.515

High

614764

KC11
Casein kinase I homolog 1

1

3

High-throughput

0.501

High

615023

KC12
Casein kinase I homolog 2

1

3

High-throughput

0.501

High

659878

PRR1
Serine/threonine-protein kinase PRR1

1

1

High-throughput

0.501

High

752178

KSP1
Serine/threonine-protein kinase KSP1

1

3

High-throughput

0.501

High

866856

STE20
Serine/threonine-protein kinase STE20

1

2

High-throughput

0.501

High

866872

SKM1
Serine/threonine-protein kinase SKM1

1

2

High-throughput

0.501

High

866873

SKS1
Serine/threonine-protein kinase SKS1

1

3

High-throughput

0.501

High

763268

NPT1
Nicotinate phosphoribosyltransferase

1

0

High-throughput

0.493

High

730489

NNK1
Nitrogen network kinase 1

1

0

High-throughput

0.480

High

141464

RS9A
Small ribosomal subunit protein uS4A

1

3

High-throughput

0.479

High

383286

RL25
Large ribosomal subunit protein uL23

1

2

High-throughput

0.479

High

405763

RL26A
Large ribosomal subunit protein uL24A

1

4

High-throughput

0.479

High

407234

RS3
Small ribosomal subunit protein uS3

1

2

High-throughput

0.479

High

408053

RS13
Small ribosomal subunit protein uS15

1

1

High-throughput

0.479

High

413650

RS14A
Small ribosomal subunit protein uS11A

1

2

High-throughput

0.479

High

426089

RS19A
Small ribosomal subunit protein eS19A

1

1

High-throughput

0.479

High

480248

RS6A
Small ribosomal subunit protein eS6A

1

4

High-throughput

0.479

High

632021

RS2
Small ribosomal subunit protein uS5

1

3

High-throughput

0.479

High

634433

SPB1
27S pre-rRNA

1

5

High-throughput

0.479

High

638832

SPB4
ATP-dependent rRNA helicase SPB4

1

9

High-throughput

0.479

High

645585

RS7A
Small ribosomal subunit protein eS7A

1

2

High-throughput

0.479

High

663001

TF2B
Transcription initiation factor IIB

1

4

High-throughput

0.479

High

688364

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

2

High-throughput

0.479

High

699711

DRS1
ATP-dependent RNA helicase DRS1

1

10

High-throughput

0.479

High

703093

MRT4
Ribosome assembly factor MRT4

1

4

High-throughput

0.479

High

715470

RRP1
Ribosomal RNA-processing protein 1

1

4

High-throughput

0.479

High

730057

RS27A
Small ribosomal subunit protein eS27A

1

2

High-throughput

0.479

High

731846

EBP2
rRNA-processing protein EBP2

1

2

High-throughput

0.479

High

746258

YBC8
UPF0642 protein YBL028C

1

1

High-throughput

0.479

High

754164

CIC1
Proteasome-interacting protein CIC1

1

2

High-throughput

0.479

High

755314

RPF1
Ribosome production factor 1

1

3

High-throughput

0.479

High

764220

NOC2
Nucleolar complex protein 2

1

2

High-throughput

0.479

High

766585

NOP16
Nucleolar protein 16

1

1

High-throughput

0.479

High

766680

NUG1
Nuclear GTP-binding protein NUG1

1

2

High-throughput

0.479

High

768033

NSA2
Ribosome biogenesis protein NSA2

1

2

High-throughput

0.479

High

776483

RLP7
Ribosome biogenesis protein RLP7

1

4

High-throughput

0.479

High

797381

LOC1
60S ribosomal subunit assembly/export protein LOC1

1

1

High-throughput

0.479

High

864535

TR112
Multifunctional methyltransferase subunit TRM112

1

1

Small-scale

0.479

High

866246

NOP15
Ribosome biogenesis protein 15

1

2

High-throughput

0.479

High

866852

H3
Histone H3

1

4

High-throughput

0.479

High

866854

RS15
Small ribosomal subunit protein uS19

1

2

High-throughput

0.479

High

866855

NOG1
Nucleolar GTP-binding protein 1

1

3

High-throughput

0.479

High

866857

HAS1
ATP-dependent RNA helicase HAS1

1

12

High-throughput

0.479

High

866858

RRB1
Ribosome assembly protein RRB1

1

6

High-throughput

0.479

High

866859

PUF6
Pumilio homology domain family member 6

1

2

High-throughput

0.479

High

866860

ERB1
Ribosome biogenesis protein ERB1

1

4

High-throughput

0.479

High

866862

NOC3
Nucleolar complex-associated protein 3

1

3

High-throughput

0.479

High

866863

NOP12
Nucleolar protein 12

1

4

High-throughput

0.479

High

866864

BRX1
Ribosome biogenesis protein BRX1

1

12

High-throughput

0.479

High

866865

RS10A
Small ribosomal subunit protein eS10A

1

2

High-throughput

0.479

High

866866

RRS1
Regulator of ribosome biosynthesis

1

2

High-throughput

0.479

High

866868

YTM1
Ribosome biogenesis protein YTM1

1

6

High-throughput

0.479

High

866869

YG11A
Transposon Ty1-GR1 Gag polyprotein

1

1

High-throughput

0.479

High

866870

YRA1
RNA annealing protein YRA1

1

4

High-throughput

0.479

High

866871

DBP10
ATP-dependent RNA helicase DBP10

1

8

High-throughput

0.479

High

866853

BCK1
Serine/threonine-protein kinase BCK1/SLK1/SSP31

1

3

High-throughput

0.457

High

494676

HSP72
Heat shock protein SSA2

1

9

High-throughput

0.445

High

769142

SSB2
Ribosome-associated molecular chaperone SSB2

1

8

High-throughput

0.445

High

866861

FKBP4
FK506-binding protein 4

1

5

High-throughput

0.445

High

358199

RS17A
Small ribosomal subunit protein eS17A

1

1

High-throughput

0.437

High

472334

RL31A
Large ribosomal subunit protein eL31A

1

2

High-throughput

0.437

High

480815

RS8A
Small ribosomal subunit protein eS8A

1

2

High-throughput

0.437

High

482397

RS18A
Small ribosomal subunit protein uS13A

1

2

High-throughput

0.437

High

544217

HSC82
ATP-dependent molecular chaperone HSC82

1

2

High-throughput

0.437

High

700561

RSSA1
Small ribosomal subunit protein uS2A

1

3

High-throughput

0.437

High

706421

RS3A1
Small ribosomal subunit protein eS1A

1

3

High-throughput

0.437

High

752597

RS20
Small ribosomal subunit protein uS10

1

2

High-throughput

0.437

High

762450

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.437

High

820105

RS12
Small ribosomal subunit protein eS12

1

2

High-throughput

0.437

High


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024