Protein: NOP3
Serine/arginine (SR)-type shuttling mRNA binding protein NPL3 (Mitochondrial targeting suppressor 1 protein) (Nuclear polyadenylated RNA-binding protein 1) (Nuclear protein localization protein 3) (Polyadenylate-binding protein NPL3)

Gene: NOP3, NPL3
Organism: Saccharomyces cerevisiae S288C
Interactions: 233
UniProt ID: Q01560

Gene Ontology (top 5):
GO:0000398 - mRNA splicing, via spliceosome
GO:0000993 - RNA polymerase II complex binding
GO:0003729 - mRNA binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

965466

NOP3
Serine/arginine

8

18

Small-scale

0.970

High

965478

SKY1
Serine/threonine-protein kinase SKY1

7

20

Small-scale

0.963

High

710199

NCBP1
Nuclear cap-binding protein complex subunit 1

7

11

Small-scale

0.951

High

965508

NCBP2
Nuclear cap-binding protein subunit 2

5

20

Small-scale

0.922

High

633981

GBP2
Serine/arginine

5

20

Small-scale

0.909

High

965521

MTR10
mRNA transport regulator MTR10

4

18

Small-scale

0.893

High

960462

NAM8
Protein NAM8

4

19

Small-scale

0.892

High

962579

RU17
U1 small nuclear ribonucleoprotein 70 kDa homolog

4

20

Small-scale

0.878

High

696660

RU1A
U1 small nuclear ribonucleoprotein A

4

1

Small-scale

0.878

High

694191

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

4

20

Small-scale

0.875

High

965513

YRA1
RNA annealing protein YRA1

4

20

Small-scale

0.874

High

965484

CTK1
CTD kinase subunit alpha

3

20

Small-scale

0.861

High

407253

RS3
Small ribosomal subunit protein uS3

3

5

High-throughput

0.827

High

743641

HMT1
Protein arginine N-methyltransferase 1

13

7

Small-scale

0.764

High

376899

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

2

19

Small-scale

0.754

High

965515

BBP
Branchpoint-bridging protein

2

15

Small-scale

0.754

High

965523

HRP1
Nuclear polyadenylated RNA-binding protein 4

2

20

Small-scale

0.754

High

965480

SNU56
56 kDa U1 small nuclear ribonucleoprotein component

2

0

Small-scale

0.728

High

440083

RPB2
DNA-directed RNA polymerase II subunit RPB2

2

0

Small-scale

0.716

High

965522

MEX67
mRNA export factor MEX67

5

8

Small-scale

0.714

High

383302

RL25
Large ribosomal subunit protein uL23

2

6

Small-scale

0.694

High

693146

CDC5
Cell cycle serine/threonine-protein kinase CDC5/MSD2

1

2

Small-scale

0.691

High

775547

SGN1
RNA-binding protein SGN1

1

20

High-throughput

0.691

High

965506

HRK1
Serine/threonine-protein kinase HRK1

1

7

High-throughput

0.691

High

375480

RPB1
DNA-directed RNA polymerase II subunit RPB1

4

4

Small-scale

0.680

High

965471

XRN2
5'-3' exoribonuclease 2

4

12

Small-scale

0.676

High

774814

AIR1
Protein AIR1

3

14

Small-scale

0.672

High

648417

NSR1
Nuclear localization sequence-binding protein

1

18

Small-scale

0.656

High

512380

SSB1
Ribosome-associated molecular chaperone SSB1

3

9

Small-scale

0.656

High

965517

AIR2
Protein AIR2

5

14

Small-scale

0.651

High

550103

CSK21
Casein kinase II subunit alpha

1

20

Small-scale

0.647

High

565743

PHO85
Cyclin-dependent protein kinase PHO85

1

12

Small-scale

0.647

High

765038

IF4F1
Eukaryotic initiation factor 4F subunit p150

3

15

Small-scale

0.646

High

628373

SIS1
Protein SIS1

3

2

High-throughput

0.643

High

416057

DED1
ATP-dependent RNA helicase DED1

3

9

Small-scale

0.642

High

366749

HSP82
ATP-dependent molecular chaperone HSP82

3

5

High-throughput

0.640

High

524419

CAF20
Cap-associated protein CAF20

3

2

Small-scale

0.640

High

558208

RPB3
DNA-directed RNA polymerase II subunit RPB3

3

2

Small-scale

0.640

High

605126

XRN1
5'-3' exoribonuclease 1

3

12

Small-scale

0.640

High

632035

RS2
Small ribosomal subunit protein uS5

3

8

Small-scale

0.640

High

732383

MUD2
Splicing factor MUD2

3

1

Small-scale

0.640

High

492152

HSP71
Heat shock protein SSA1

3

7

High-throughput

0.633

High

765363

RSP5
E3 ubiquitin-protein ligase RSP5

2

18

Small-scale

0.619

High

485576

SSBP1
Single-stranded nucleic acid-binding protein

1

19

Small-scale

0.618

High

606214

TRX1
Thioredoxin-1

1

2

High-throughput

0.618

High

611747

TRX2
Thioredoxin-2

1

1

High-throughput

0.618

High

615173

BUR1
Serine/threonine-protein kinase BUR1

1

15

Small-scale

0.618

High

634180

SRO9
RNA-binding protein SRO9

1

20

Small-scale

0.618

High

757864

HRB1
Serine/arginine

1

19

Small-scale

0.618

High

758922

NAB3
Nuclear polyadenylated RNA-binding protein 3

1

1

Small-scale

0.618

High

863164

NRD1
Protein NRD1

1

3

Small-scale

0.618

High

965469

CUS1
Cold sensitive U2 snRNA suppressor 1

1

4

High-throughput

0.618

High

965481

ARX1
Probable metalloprotease ARX1

2

3

Small-scale

0.601

High

624156

DBP2
ATP-dependent RNA helicase DBP2

2

7

Small-scale

0.600

High

965498

SUB2
ATP-dependent RNA helicase SUB2

2

20

Small-scale

0.600

High

965489

RU1C
U1 small nuclear ribonucleoprotein C

2

1

Small-scale

0.595

High

482406

RS18A
Small ribosomal subunit protein uS13A

2

2

High-throughput

0.584

High

645598

RS7A
Small ribosomal subunit protein eS7A

2

4

High-throughput

0.584

High

700574

RSSA1
Small ribosomal subunit protein uS2A

2

7

High-throughput

0.584

High

742943

GBLP
Small ribosomal subunit protein RACK1

2

20

High-throughput

0.584

High

752612

RS20
Small ribosomal subunit protein uS10

2

4

High-throughput

0.584

High

820117

RS12
Small ribosomal subunit protein eS12

2

2

High-throughput

0.584

High

858813

DXO
Decapping nuclease RAI1

2

1

Small-scale

0.584

High

965467

RS15
Small ribosomal subunit protein uS19

2

7

High-throughput

0.584

High

965499

LUC7
Protein LUC7

2

9

Small-scale

0.584

High

544259

HSC82
ATP-dependent molecular chaperone HSC82

2

5

High-throughput

0.571

High

965497

BRE1
E3 ubiquitin-protein ligase BRE1

2

16

Small-scale

0.571

High

965495

URN1
Pre-mRNA-splicing factor URN1

2

0

High-throughput

0.569

High

701043

SMY2
Protein SMY2

2

0

Small-scale

0.559

High

860151

SNU71
U1 small nuclear ribonucleoprotein component SNU71

2

0

Small-scale

0.559

High

965512

RRP6
Exosome complex exonuclease RRP6

1

2

Small-scale

0.552

High

769207

SSB2
Ribosome-associated molecular chaperone SSB2

2

9

High-throughput

0.552

High

695320

HSP7F
Heat shock protein homolog SSE1

1

9

High-throughput

0.536

High

860347

EIF2A
Eukaryotic translation initiation factor 2A

1

7

High-throughput

0.536

High

965476

GCN5
Histone acetyltransferase GCN5

1

20

High-throughput

0.536

High

965493

MAG2
E3 ubiquitin-protein ligase MAG2

1

1

High-throughput

0.536

High

358211

RS17A
Small ribosomal subunit protein eS17A

2

4

High-throughput

0.533

High

426101

RS19A
Small ribosomal subunit protein eS19A

2

7

High-throughput

0.533

High

471203

RS22A
Small ribosomal subunit protein uS8A

2

2

High-throughput

0.533

High

480261

RS6A
Small ribosomal subunit protein eS6A

2

8

High-throughput

0.533

High

480826

RS8A
Small ribosomal subunit protein eS8A

2

4

High-throughput

0.533

High

706435

RS3A1
Small ribosomal subunit protein eS1A

2

5

High-throughput

0.533

High

479371

RS23B
Small ribosomal subunit protein uS12B

1

0

High-throughput

0.517

High

756855

RIX1
Pre-rRNA-processing protein RIX1

1

1

Small-scale

0.515

High

763515

NUP60
Nucleoporin NUP60

1

1

Small-scale

0.515

High

965468

MLP1
Protein MLP1

1

19

Small-scale

0.515

High

965509

KEL3
Kelch repeat-containing protein 3

1

5

High-throughput

0.515

High

965518

NOP58
Nucleolar protein 58

1

4

High-throughput

0.515

High

692055

NAB2
Nuclear polyadenylated RNA-binding protein NAB2

1

7

Small-scale

0.508

High

659827

SBA1
Co-chaperone protein SBA1

1

0

Small-scale

0.504

High

703258

PRP40
Pre-mRNA-processing protein PRP40

1

7

High-throughput

0.501

High

765152

IF4F2
Eukaryotic initiation factor 4F subunit p130

1

20

Small-scale

0.501

High

965479

ENT5
Epsin-5

1

1

Small-scale

0.501

High

756378

NMD3
60S ribosomal export protein NMD3

1

0

Small-scale

0.493

High

965500

NOP6
Nucleolar protein 6

1

2

High-throughput

0.489

High

624643

PCL1
PHO85 cyclin-1

1

0

Small-scale

0.480

High

797304

WWM1
WW domain-containing protein WWM1

1

0

High-throughput

0.480

High

141474

RS9A
Small ribosomal subunit protein uS4A

1

8

High-throughput

0.479

High

355594

H2B1
Histone H2B.1

1

6

Small-scale

0.479

High

355978

H2B2
Histone H2B.2

1

6

Small-scale

0.479

High

356663

H4
Histone H4

1

10

Small-scale

0.479

High

408066

RS13
Small ribosomal subunit protein uS15

1

7

High-throughput

0.479

High

410442

SC160
Protein SCP160

1

20

High-throughput

0.479

High

413661

RS14A
Small ribosomal subunit protein uS11A

1

5

High-throughput

0.479

High

479627

RS30A
Small ribosomal subunit protein eS30A

1

2

High-throughput

0.479

High

479804

RS4A
Small ribosomal subunit protein eS4A

1

4

High-throughput

0.479

High

482921

RL35A
Large ribosomal subunit protein uL29A

1

3

High-throughput

0.479

High

542144

CYC8
General transcriptional corepressor CYC8

1

12

Small-scale

0.479

High

616116

PRP28
Pre-mRNA-splicing ATP-dependent RNA helicase PRP28

1

18

Small-scale

0.479

High

619163

SPT6
Transcription elongation factor SPT6

1

1

Small-scale

0.479

High

630091

SNT1
Probable DNA-binding protein SNT1

1

3

Small-scale

0.479

High

634436

SPB1
27S pre-rRNA

1

11

High-throughput

0.479

High

635711

TAH1
TPR repeat-containing protein associated with Hsp90

1

6

Small-scale

0.479

High

644940

RS5
Small ribosomal subunit protein uS7

1

7

High-throughput

0.479

High

645105

RL16A
Large ribosomal subunit protein uL13A

1

5

High-throughput

0.479

High

650368

SPT5
Transcription elongation factor SPT5

1

2

Small-scale

0.479

High

663059

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.479

High

665002

BMH1
Protein BMH1

1

6

High-throughput

0.479

High

688379

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

1

High-throughput

0.479

High

692340

PRP19
Pre-mRNA-processing factor 19

1

14

Small-scale

0.479

High

696388

PP12
Serine/threonine-protein phosphatase PP1-2

1

13

Small-scale

0.479

High

697423

CHD1
Chromo domain-containing protein 1

1

19

Small-scale

0.479

High

703099

MRT4
Ribosome assembly factor MRT4

1

5

Small-scale

0.479

High

730069

RS27A
Small ribosomal subunit protein eS27A

1

3

High-throughput

0.479

High

730889

CENPA
Histone H3-like centromeric protein CSE4

1

3

High-throughput

0.479

High

731607

EAP1
Protein EAP1

1

2

High-throughput

0.479

High

732683

SWD2
COMPASS component SWD2

1

19

Small-scale

0.479

High

746765

FL2D
Protein MUM2

1

1

Small-scale

0.479

High

756559

KOG1
Target of rapamycin complex 1 subunit KOG1

1

8

Small-scale

0.479

High

756706

NACA
Nascent polypeptide-associated complex subunit alpha

1

1

High-throughput

0.479

High

767818

LSM4
U6 snRNA-associated Sm-like protein LSm4

1

3

Small-scale

0.479

High

768034

NSA2
Ribosome biogenesis protein NSA2

1

7

High-throughput

0.479

High

770056

RIO2
Serine/threonine-protein kinase RIO2

1

9

High-throughput

0.479

High

775823

DSN1
Kinetochore-associated protein DSN1

1

2

High-throughput

0.479

High

778627

PRP17
Pre-mRNA-processing factor 17

1

18

Small-scale

0.479

High

784201

RL10
Large ribosomal subunit protein uL16

1

1

Small-scale

0.479

High

797534

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

14

High-throughput

0.479

High

809742

CTK2
CTD kinase subunit beta

1

14

Small-scale

0.479

High

809753

CTK3
CTD kinase subunit gamma

1

1

Small-scale

0.479

High

810531

LSM1
Sm-like protein LSm1

1

9

Small-scale

0.479

High

810585

ALB1
Ribosome biogenesis protein ALB1

1

1

High-throughput

0.479

High

810898

MTR4
ATP-dependent RNA helicase DOB1

1

20

Small-scale

0.479

High

812078

MOG1
Nuclear import protein MOG1

1

1

High-throughput

0.479

High

816532

RS7B
Small ribosomal subunit protein eS7B

1

4

High-throughput

0.479

High

819874

TRF5
Poly(A) RNA polymerase protein 1

1

11

Small-scale

0.479

High

859409

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

1

11

Small-scale

0.479

High

859618

LSG1
Large subunit GTPase 1

1

9

High-throughput

0.479

High

862763

THO2
THO complex subunit 2

1

16

Small-scale

0.479

High

863691

PAP2
Poly(A) RNA polymerase protein 2

1

11

Small-scale

0.479

High

864665

NOG2
Nucleolar GTP-binding protein 2

1

9

High-throughput

0.479

High

865289

GIS2
Zinc finger protein GIS2

1

15

High-throughput

0.479

High

865605

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

10

High-throughput

0.479

High

953678

CTR9
RNA polymerase-associated protein CTR9

1

8

Small-scale

0.479

High

965474

HOT1
High-osmolarity-induced transcription protein 1

1

1

Small-scale

0.479

High

965475

TOM1
E3 ubiquitin-protein ligase TOM1

1

18

High-throughput

0.479

High

965483

RUVB1
RuvB-like protein 1

1

5

High-throughput

0.479

High

965486

PUF6
Pumilio homology domain family member 6

1

12

Small-scale

0.479

High

965487

RRP5
rRNA biogenesis protein RRP5

1

13

High-throughput

0.479

High

965491

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

2

High-throughput

0.479

High

965492

TFC6
Transcription factor tau 91 kDa subunit

1

2

High-throughput

0.479

High

965496

TSR1
Ribosome biogenesis protein TSR1

1

5

High-throughput

0.479

High

965502

BUD20
Bud site selection protein 20

1

1

High-throughput

0.479

High

965504

SGO1
Shugoshin

1

1

High-throughput

0.479

High

965510

TMA46
Translation machinery-associated protein 46

1

1

High-throughput

0.479

High

965514

MAK21
Ribosome biogenesis protein MAK21

1

11

High-throughput

0.479

High

965516

RUVB2
RuvB-like protein 2

1

5

High-throughput

0.479

High

655883

GAR1
H/ACA ribonucleoprotein complex subunit GAR1

1

4

Small-scale

0.464

High

696886

RML2
Large ribosomal subunit protein uL2m

1

5

Small-scale

0.464

High

593084

RPB4
DNA-directed RNA polymerase II subunit RPB4

1

0

Small-scale

0.458

High

593179

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

1

0

Small-scale

0.458

High

748173

AIM4
Altered inheritance of mitochondria protein 4

1

0

High-throughput

0.458

High

755976

YHS7
Uncharacterized protein YHR127W

1

0

High-throughput

0.458

High

756026

NSG1
Protein NSG1

1

0

High-throughput

0.458

High

759428

STM1
Suppressor protein STM1

1

0

High-throughput

0.458

High

765204

RS26A
Small ribosomal subunit protein eS26A

1

0

High-throughput

0.458

High

766416

PXP1
2-hydroxyacyl-CoA lyase

1

0

High-throughput

0.458

High

774134

TM108
Protein TMA108

1

0

High-throughput

0.458

High

805116

SAC3
Nuclear mRNA export protein SAC3

1

0

High-throughput

0.458

High

865558

SQS1
Protein SQS1

1

0

High-throughput

0.458

High

965472

LGE1
Transcriptional regulatory protein LGE1

1

0

High-throughput

0.458

High

965473

IMA1
Importin subunit alpha

1

0

Small-scale

0.458

High

965477

CWC21
Pre-mRNA-splicing factor CWC21

1

0

Small-scale

0.458

High

965482

MTQ2
eRF1 methyltransferase catalytic subunit MTQ2

1

0

High-throughput

0.458

High

965485

RRP17
Ribosomal RNA-processing protein 17

1

0

High-throughput

0.458

High

965488

RBS1
RNA-binding suppressor of PAS kinase protein 1

1

0

Small-scale

0.458

High

965490

BUR2
Protein BUR2

1

0

Small-scale

0.458

High

965494

IWS1
Transcription factor SPN1

1

0

Small-scale

0.458

High

965501

UBR2
E3 ubiquitin-protein ligase UBR2

1

0

High-throughput

0.458

High

965505

MCA1
Metacaspase-1

1

0

High-throughput

0.458

High

965511

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.458

High

812531

ENT3
Epsin-3

1

1

Small-scale

0.457

High

965470

NU116
Nucleoporin NUP116/NSP116

1

6

Small-scale

0.457

High

680935

HS104
Heat shock protein 104

1

2

High-throughput

0.445

High

705542

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.445

High

715372

SPT7
Transcriptional activator SPT7

1

13

High-throughput

0.445

High

761286

CAJ1
Protein CAJ1

1

1

High-throughput

0.445

High

959989

SEN1
Helicase SEN1

1

20

Small-scale

0.445

High

141755

THP2
THO complex subunit THP2

1

2

High-throughput

0.437

High

405780

RL26A
Large ribosomal subunit protein uL24A

1

12

High-throughput

0.437

High

406049

RL33A
Large ribosomal subunit protein eL33A

1

1

High-throughput

0.437

High

406596

RL22A
Large ribosomal subunit protein eL22A

1

1

High-throughput

0.437

High

407574

RS9B
Small ribosomal subunit protein uS4B

1

8

High-throughput

0.437

High

420324

CALM
Calmodulin

1

1

High-throughput

0.437

High

426324

RS19B
Small ribosomal subunit protein eS19B

1

7

High-throughput

0.437

High

472349

RL31A
Large ribosomal subunit protein eL31A

1

5

High-throughput

0.437

High

479519

RS24A
Small ribosomal subunit protein eS24A

1

3

High-throughput

0.437

High

481549

RS11B
Small ribosomal subunit protein uS17B

1

1

High-throughput

0.437

High

481815

RS16B
Small ribosomal subunit protein uS9B

1

12

High-throughput

0.437

High

630884

NLE1
Ribosome assembly protein 4

1

20

High-throughput

0.437

High

634734

KRR1
KRR1 small subunit processome component

1

8

High-throughput

0.437

High

762473

LAA1
AP-1 accessory protein LAA1

1

2

High-throughput

0.437

High

773973

MLP2
Protein MLP2

1

18

High-throughput

0.437

High

866781

SAM50
Sorting assembly machinery 50 kDa subunit

1

1

High-throughput

0.437

High

881720

RL22B
Large ribosomal subunit protein eL22B

1

1

High-throughput

0.437

High

959839

NUM1
Nuclear migration protein NUM1

1

16

High-throughput

0.437

High

965507

RS10A
Small ribosomal subunit protein eS10A

1

6

High-throughput

0.437

High

757453

SPT8
Transcription factor SPT8

1

0

High-throughput

0.426

High

762154

YM11
Uncharacterized protein YMR124W

1

0

High-throughput

0.426

High

541776

SEC63
Protein translocation protein SEC63

1

6

High-throughput

0.407

High

760934

TCPD
T-complex protein 1 subunit delta

1

1

High-throughput

0.407

High

772582

JEM1
DnaJ-like chaperone JEM1

1

1

High-throughput

0.407

High

772918

TCPE
T-complex protein 1 subunit epsilon

1

1

High-throughput

0.407

High

798018

ERJ5
ER-localized J domain-containing protein 5

1

1

High-throughput

0.407

High

687109

VPS10
Vacuolar protein sorting/targeting protein VPS10

2

0

High-throughput

0.324

High

965503

AUS1
ATP-dependent permease AUS1

1

0

High-throughput

0.261

Low

471523

RS28B
Small ribosomal subunit protein eS28B

1

0

High-throughput

0.249

Low

618513

HXT2
High-affinity glucose transporter HXT2

1

0

High-throughput

0.249

Low

692878

SPT16
FACT complex subunit SPT16

1

0

Small-scale

0.249

Low

780519

RS29A
Small ribosomal subunit protein uS14A

1

0

High-throughput

0.249

Low

965519

RS21B
Small ribosomal subunit protein eS21B

1

0

High-throughput

0.249

Low

965520

RS25A
Small ribosomal subunit protein eS25A

1

0

High-throughput

0.249

Low

761055

TCPZ
T-complex protein 1 subunit zeta

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024