HitPredict - High confidence protein-protein interactions

Protein: THRB
Prothrombin (EC 3.4.21.5) (Coagulation factor II) [Cleaved into: Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain]

Gene: THRB, F2
Organism: Mus musculus
Interactions: 7
UniProt ID: P19221

Gene Ontology (top 5):
GO:0001530 - lipopolysaccharide binding
GO:0004175 - endopeptidase activity
GO:0004252 - serine-type endopeptidase activity
GO:0005509 - calcium ion binding
GO:0005615 - extracellular space

Download interactions: TXT MITAB-2.5

Interaction	Interactor	Experiments	Homologs	Category	Interaction Score	Confidence
619186	SPA3C Serine protease inhibitor A3C	1	20	Small-scale	0.618	High
148067	PAR3 Proteinase-activated receptor 3	1	6	Small-scale	0.501	High
312735	PAR4 Proteinase-activated receptor 4	1	6	Small-scale	0.501	High
619188	SAP Prosaposin	1	1	High-throughput	0.479	High
619187	Q3UJF1 Histone deacetylase	1	4	High-throughput	0.437	High
619189	BICD1 Protein bicaudal D homolog 1	1	4	High-throughput	0.407	High
619190	HDAC5 Histone deacetylase 5	1	4	High-throughput	0.407	High

Service provided by Combinatics, Japan

Last updated: 11Aug2025