Protein: CLU
Clustered mitochondria protein 1 (Translation initiation factor 31) (eIF3-associated protein p135)

Gene: CLU, CLU1
Organism: Saccharomyces cerevisiae S288C
Interactions: 178
UniProt ID: Q03690

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0003729 - mRNA binding
GO:0005737 - cytoplasm
GO:0010494 - cytoplasmic stress granule
GO:0048312 - intracellular distribution of mitochondria

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

492278

HSP71
Heat shock protein SSA1

3

8

High-throughput

0.656

High

366812

HSP82
ATP-dependent molecular chaperone HSP82

3

3

High-throughput

0.633

High

742973

GBLP
Small ribosomal subunit protein RACK1

2

1

High-throughput

0.611

High

864595

BRE5
UBP3-associated protein BRE5

2

1

High-throughput

0.601

High

965029

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

2

3

High-throughput

0.601

High

657275

URA7
CTP synthase 1

2

0

High-throughput

0.595

High

746537

IMB2
Importin subunit beta-2

2

0

High-throughput

0.595

High

975954

GCN5
Histone acetyltransferase GCN5

2

3

High-throughput

0.574

High

680968

HS104
Heat shock protein 104

2

2

High-throughput

0.571

High

519625

ERF1
Eukaryotic peptide chain release factor subunit 1

2

0

High-throughput

0.563

High

744234

MAK5
ATP-dependent RNA helicase MAK5

2

0

High-throughput

0.563

High

383330

RL25
Large ribosomal subunit protein uL23

2

0

High-throughput

0.559

High

524432

CAF20
Cap-associated protein CAF20

2

0

High-throughput

0.559

High

494836

HSP72
Heat shock protein SSA2

2

8

High-throughput

0.552

High

695413

HSP7F
Heat shock protein homolog SSE1

2

11

High-throughput

0.552

High

769334

SSB2
Ribosome-associated molecular chaperone SSB2

2

8

High-throughput

0.552

High

581317

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

2

2

High-throughput

0.537

High

964142

MCE1
mRNA-capping enzyme subunit alpha

2

2

High-throughput

0.537

High

339817

CDK1
Cyclin-dependent kinase 1

1

4

High-throughput

0.536

High

454655

TBA3
Tubulin alpha-3 chain

1

3

High-throughput

0.536

High

693152

CDC5
Cell cycle serine/threonine-protein kinase CDC5/MSD2

1

1

Small-scale

0.536

High

752869

SYNC
Asparagine--tRNA ligase, cytoplasmic

1

1

High-throughput

0.536

High

775550

SGN1
RNA-binding protein SGN1

1

2

High-throughput

0.536

High

973444

NOG1
Nucleolar GTP-binding protein 1

1

1

High-throughput

0.536

High

977167

HEL2
E3 ubiquitin-protein ligase HEL2

1

1

High-throughput

0.536

High

797561

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

1

High-throughput

0.533

High

977163

EIF3G
Eukaryotic translation initiation factor 3 subunit G

1

1

Small-scale

0.527

High

498584

METK1
S-adenosylmethionine synthase 1

1

0

High-throughput

0.513

High

597591

FAR1
Cyclin-dependent kinase inhibitor FAR1

1

0

High-throughput

0.513

High

696397

PP12
Serine/threonine-protein phosphatase PP1-2

1

0

High-throughput

0.513

High

763829

RBG1
Ribosome-interacting GTPase 1

1

0

High-throughput

0.513

High

785189

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.513

High

809546

CWC26
Pre-mRNA-splicing factor CWC26

1

0

High-throughput

0.513

High

814715

LCF4
Long-chain-fatty-acid--CoA ligase 4

1

0

High-throughput

0.513

High

977170

PRP11
Pre-mRNA-splicing factor PRP11

1

0

High-throughput

0.513

High

977180

INP53
Polyphosphatidylinositol phosphatase INP53

1

0

High-throughput

0.513

High

810484

YJO4
Uncharacterized protein YJL144W

1

0

High-throughput

0.493

High

865393

YNX4
Uncharacterized globin-like protein YNL234W

1

0

High-throughput

0.493

High

561904

TUP1
General transcriptional corepressor TUP1

1

2

High-throughput

0.489

High

586438

PRP6
Pre-mRNA-splicing factor 6

1

3

High-throughput

0.489

High

715383

SPT7
Transcriptional activator SPT7

1

3

High-throughput

0.489

High

744164

ATR
Serine/threonine-protein kinase MEC1

1

2

High-throughput

0.489

High

744681

TAF5
Transcription initiation factor TFIID subunit 5

1

3

High-throughput

0.489

High

758700

TEM1
Protein TEM1

1

1

High-throughput

0.489

High

774664

LYS12
Homoisocitrate dehydrogenase, mitochondrial

1

1

High-throughput

0.489

High

864673

NOG2
Nucleolar GTP-binding protein 2

1

1

High-throughput

0.489

High

977164

KU80
ATP-dependent DNA helicase II subunit 2

1

2

High-throughput

0.489

High

141504

RS9A
Small ribosomal subunit protein uS4A

1

1

High-throughput

0.479

High

404689

RL7A
Large ribosomal subunit protein uL30A

1

1

High-throughput

0.479

High

544327

HSC82
ATP-dependent molecular chaperone HSC82

1

3

High-throughput

0.479

High

564362

RL8A
Large ribosomal subunit protein eL8A

1

2

High-throughput

0.479

High

567996

MDHM
Malate dehydrogenase, mitochondrial

1

1

Small-scale

0.479

High

606127

RAD53
Serine/threonine-protein kinase RAD53

1

2

High-throughput

0.479

High

638843

SPB4
ATP-dependent rRNA helicase SPB4

1

1

High-throughput

0.479

High

645120

RL16A
Large ribosomal subunit protein uL13A

1

2

High-throughput

0.479

High

645270

RL16B
Large ribosomal subunit protein uL13B

1

2

High-throughput

0.479

High

665028

BMH1
Protein BMH1

1

6

High-throughput

0.479

High

700602

RSSA1
Small ribosomal subunit protein uS2A

1

1

High-throughput

0.479

High

732782

RL14A
Large ribosomal subunit protein eL14A

1

1

High-throughput

0.479

High

752649

RS20
Small ribosomal subunit protein uS10

1

2

High-throughput

0.479

High

762016

DHH1
ATP-dependent RNA helicase DHH1

1

1

High-throughput

0.479

High

763897

IF2P
Eukaryotic translation initiation factor 5B

1

2

High-throughput

0.479

High

767080

ARB1
ABC transporter ATP-binding protein ARB1

1

1

Small-scale

0.479

High

774144

TM108
Protein TMA108

1

1

High-throughput

0.479

High

961473

CDC14
Tyrosine-protein phosphatase CDC14

1

2

Small-scale

0.479

High

975812

TOM1
E3 ubiquitin-protein ligase TOM1

1

1

High-throughput

0.479

High

977178

NEW1
[NU+] prion formation protein 1

1

1

High-throughput

0.479

High

376915

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

0

Small-scale

0.458

High

399616

RLA0
Large ribosomal subunit protein uL10

1

0

High-throughput

0.458

High

405810

RL26A
Large ribosomal subunit protein uL24A

1

0

High-throughput

0.458

High

406399

RL15A
Large ribosomal subunit protein eL15A

1

0

High-throughput

0.458

High

407288

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

408100

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.458

High

413689

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.458

High

426129

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.458

High

482436

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.458

High

499059

RL4A
Large ribosomal subunit protein uL4A

1

0

High-throughput

0.458

High

535103

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.458

High

615300

IF5A1
Eukaryotic translation initiation factor 5A-1

1

0

Small-scale

0.458

High

632066

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.458

High

701066

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

703729

PRS6A
26S proteasome regulatory subunit 6A

1

0

High-throughput

0.458

High

730096

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.458

High

731488

YRA2
RNA annealing protein YRA2

1

0

High-throughput

0.458

High

731613

EAP1
Protein EAP1

1

0

High-throughput

0.458

High

743308

RL32
Large ribosomal subunit protein eL32

1

0

High-throughput

0.458

High

748184

AIM4
Altered inheritance of mitochondria protein 4

1

0

High-throughput

0.458

High

753936

RPN1
26S proteasome regulatory subunit RPN1

1

0

High-throughput

0.458

High

757197

2A5D
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform

1

0

High-throughput

0.458

High

784215

RL10
Large ribosomal subunit protein uL16

1

0

High-throughput

0.458

High

820148

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

865869

IGO1
mRNA stability protein IGO1

1

0

Small-scale

0.458

High

967732

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

972624

XRN2
5'-3' exoribonuclease 2

1

0

High-throughput

0.458

High

974310

ESP1
Separin

1

0

High-throughput

0.458

High

977169

URN1
Pre-mRNA-splicing factor URN1

1

0

High-throughput

0.458

High

977173

SGO1
Shugoshin

1

0

High-throughput

0.458

High

977174

MCA1
Metacaspase-1

1

0

High-throughput

0.458

High

977176

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.458

High

977182

CSN10
COP9 signalosome complex subunit 10

1

0

Small-scale

0.458

High

977184

CMR1
DNA damage-binding protein CMR1

1

0

High-throughput

0.458

High

512542

SSB1
Ribosome-associated molecular chaperone SSB1

1

8

High-throughput

0.445

High

696055

HSP79
Heat shock protein homolog SSE2

1

12

High-throughput

0.445

High

766181

HSP7E
Heat shock protein SSC3, mitochondrial

1

10

High-throughput

0.445

High

766690

NUG1
Nuclear GTP-binding protein NUG1

1

1

High-throughput

0.445

High

628411

SIS1
Protein SIS1

1

2

High-throughput

0.437

High

645629

RS7A
Small ribosomal subunit protein eS7A

1

1

High-throughput

0.437

High

675105

SEC1
Protein transport protein SEC1

1

1

High-throughput

0.437

High

730907

CENPA
Histone H3-like centromeric protein CSE4

1

1

High-throughput

0.437

High

753329

MUP3
Low-affinity methionine permease

1

1

High-throughput

0.437

High

902034

H3
Histone H3

1

1

High-throughput

0.437

High

959854

NUM1
Nuclear migration protein NUM1

1

13

High-throughput

0.437

High

977177

AP3D
AP-3 complex subunit delta

1

1

High-throughput

0.437

High

633521

MAS5
Mitochondrial protein import protein MAS5

1

0

High-throughput

0.426

High

977162

ARX1
Probable metalloprotease ARX1

1

0

High-throughput

0.426

High

977181

HSP42
Heat shock protein 42

1

0

High-throughput

0.426

High

767186

PIC2
Mitochondrial phosphate carrier protein 2

1

2

High-throughput

0.407

High

837190

PHB2
Prohibitin-2

1

1

High-throughput

0.407

High

837459

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

1

High-throughput

0.407

High

867517

ALDH6
Magnesium-activated aldehyde dehydrogenase, cytosolic

1

3

High-throughput

0.407

High

970394

ADA2
Transcriptional adapter 2

1

1

High-throughput

0.407

High

977183

RUVB2
RuvB-like protein 2

1

2

High-throughput

0.407

High

977186

GLT1
Glutamate synthase [NADH]

1

1

High-throughput

0.407

High

420517

RAD3
General transcription and DNA repair factor IIH helicase subunit XPD

2

0

High-throughput

0.307

High

632582

RAD51
DNA repair protein RAD51

2

0

High-throughput

0.307

High

805230

TAF1
Transcription initiation factor TFIID subunit 1

2

0

High-throughput

0.307

High

388123

TOP1
DNA topoisomerase 1

1

0

High-throughput

0.279

Low

679839

NTH1
Endonuclease III homolog 1

1

0

High-throughput

0.279

Low

690339

CDC11
Cell division control protein 11

1

0

High-throughput

0.279

Low

731013

MAOM
NAD-dependent malic enzyme, mitochondrial

1

0

High-throughput

0.279

Low

757461

SPT8
Transcription factor SPT8

1

0

High-throughput

0.279

Low

767408

UTP7
U3 small nucleolar RNA-associated protein 7

1

0

High-throughput

0.279

Low

842075

SPT20
Transcription factor SPT20

1

0

High-throughput

0.279

Low

860481

YG2A
Zinc finger protein YGR067C

1

0

High-throughput

0.279

Low

966045

CIK1
Spindle pole body-associated protein CIK1

1

0

High-throughput

0.279

Low

977165

SEN15
tRNA-splicing endonuclease subunit SEN15

1

0

High-throughput

0.279

Low

977166

TAF9
Transcription initiation factor TFIID subunit 9

1

0

High-throughput

0.279

Low

977172

PSR2
Probable phosphatase PSR2

1

0

High-throughput

0.279

Low

977179

HFI1
Transcriptional coactivator HFI1/ADA1

1

0

High-throughput

0.279

Low

977185

YP015
Zinc finger protein YPR015C

1

0

High-throughput

0.279

Low

977188

SUS1
Transcription and mRNA export factor SUS1

1

0

High-throughput

0.279

Low

520450

RT13
Small ribosomal subunit protein mS27

1

0

High-throughput

0.269

Low

358239

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.249

Low

404905

RL9A
Large ribosomal subunit protein uL6A

1

0

High-throughput

0.249

Low

471230

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.249

Low

472374

RL31A
Large ribosomal subunit protein eL31A

1

0

High-throughput

0.249

Low

480289

RS6A
Small ribosomal subunit protein eS6A

1

0

High-throughput

0.249

Low

480858

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.249

Low

606736

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

0

High-throughput

0.249

Low

663174

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

692901

SPT16
FACT complex subunit SPT16

1

0

High-throughput

0.249

Low

706466

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.249

Low

716341

SPT10
Protein SPT10

1

0

High-throughput

0.249

Low

716498

SPT21
Protein SPT21

1

0

High-throughput

0.249

Low

745857

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

747447

PHO88
SRP-independent targeting protein 3

1

0

High-throughput

0.249

Low

757020

RPN10
26S proteasome regulatory subunit RPN10

1

0

High-throughput

0.249

Low

762516

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

768041

NSA2
Ribosome biogenesis protein NSA2

1

0

High-throughput

0.249

Low

775843

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.249

Low

866796

SAM50
Sorting assembly machinery 50 kDa subunit

1

0

High-throughput

0.249

Low

972285

RL21A
Large ribosomal subunit protein eL21A

1

0

High-throughput

0.249

Low

977168

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.249

Low

977175

ESA1
Histone acetyltransferase ESA1

1

0

Small-scale

0.249

Low

977189

ENV10
SRP-independent targeting protein 2

1

0

High-throughput

0.249

Low

399233

FUR4
Uracil permease

1

0

High-throughput

0.232

Low

427292

ILVB
Acetolactate synthase catalytic subunit, mitochondrial

1

0

High-throughput

0.232

Low

576248

ERD2
ER lumen protein-retaining receptor

1

0

High-throughput

0.232

Low

597006

ACO1
Acyl-CoA desaturase 1

1

0

High-throughput

0.232

Low

700249

PMP1
Plasma membrane ATPase proteolipid 1

1

0

High-throughput

0.232

Low

752778

LAG1
Ceramide synthase LAG1

1

0

High-throughput

0.232

Low

762108

ILV3
Dihydroxy-acid dehydratase, mitochondrial

1

0

High-throughput

0.232

Low

798002

SA155
SIT4-associating protein SAP155

1

0

High-throughput

0.232

Low

858423

SCS3
Acyl-coenzyme A diphosphatase SCS3

1

0

High-throughput

0.232

Low

858732

ERG25
C-4 methylsterol oxidase ERG25

1

0

High-throughput

0.232

Low

860164

YG1A
Uncharacterized membrane protein YGR016W

1

0

High-throughput

0.232

Low

977171

CRD1
Cardiolipin synthase

1

0

High-throughput

0.232

Low

977187

YB111
Uncharacterized helicase-like protein YBL111C

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024