HitPredict - High confidence protein-protein interactions

Protein: PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (EC 3.1.4.11) (Phosphoinositide phospholipase C-gamma-1) (Phospholipase C-gamma-1) (PLC-gamma-1)

Gene: PLCG1
Organism: Rattus norvegicus
Interactions: 10
UniProt ID: P10686

Gene Ontology (top 5):
GO:0001701 - in utero embryonic development
GO:0001726 - ruffle
GO:0004435 - phosphatidylinositol-4,5-bisphosphate phospholipase C activity
GO:0004629 - phospholipase C activity
GO:0005085 - guanyl-nucleotide exchange factor activity

Download interactions: TXT MITAB-2.5

Interaction	Interactor	Experiments	Homologs	Category	Interaction Score	Confidence
531970	NCAM1 Neural cell adhesion molecule 1	1	3	Small-scale	0.724	High
531977	AGAP2 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2	1	3	Small-scale	0.724	High
531972	GRB2 Growth factor receptor-bound protein 2	2	20	Small-scale	0.714	High
531973	FGFR1 Fibroblast growth factor receptor 1	1	20	Small-scale	0.647	High
531971	INSR Insulin receptor	1	20	Small-scale	0.618	High
531976	NTRK2 BDNF/NT-3 growth factors receptor	1	20	Small-scale	0.618	High
531969	PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1	1	9	Small-scale	0.575	High
531974	AP180 Clathrin coat assembly protein AP180	1	1	Small-scale	0.561	High
531975	SYN2 Synapsin-2	1	0	Small-scale	0.537	High

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Last updated: 11Aug2025