Protein: PSA6
Proteasome subunit alpha type-6 (Macropain subunit PRE5) (Multicatalytic endopeptidase complex subunit PRE5) (Proteasome component PRE5) (Proteinase YSCE subunit PRE5)

Gene: PSA6, PRE5
Organism: Saccharomyces cerevisiae S288C
Interactions: 85
UniProt ID: P40302

Gene Ontology (top 5):
GO:0000502 - proteasome complex
GO:0005634 - nucleus
GO:0010499 - proteasomal ubiquitin-independent protein catabolic process
GO:0019773 - proteasome core complex, alpha-subunit complex
GO:0034515 - proteasome storage granule

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

604802

PSB4
Proteasome subunit beta type-4

14

20

Small-scale

0.981

High

597247

PSA7
Probable proteasome subunit alpha type-7

8

19

Small-scale

0.966

High

619475

PSA2
Proteasome subunit alpha type-2

7

20

High-throughput

0.962

High

675421

PSB5
Proteasome subunit beta type-5

7

20

Small-scale

0.958

High

597327

PSA1
Proteasome subunit alpha type-1

6

20

Small-scale

0.943

High

771331

PSA4
Proteasome subunit alpha type-4

5

19

High-throughput

0.922

High

619363

PSA3
Proteasome subunit alpha type-3

4

19

Small-scale

0.884

High

747928

UMP1
Proteasome maturation factor UMP1

4

1

Small-scale

0.881

High

751165

PSB1
Proteasome subunit beta type-1

3

20

Small-scale

0.849

High

619976

PSB6
Proteasome subunit beta type-6

3

18

High-throughput

0.839

High

675473

PSB7
Proteasome subunit beta type-7

3

19

Small-scale

0.839

High

689185

PSA5
Proteasome subunit alpha type-5

3

18

Small-scale

0.839

High

625940

PSB2
Proteasome subunit beta type-2

2

20

High-throughput

0.776

High

731548

POC2
Proteasome assembly chaperone 2

2

1

High-throughput

0.776

High

703642

PRS6A
26S proteasome regulatory subunit 6A

2

20

High-throughput

0.754

High

771336

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

10

20

Small-scale

0.751

High

771335

BLM10
Proteasome activator BLM10

2

7

Small-scale

0.727

High

756940

RPN10
26S proteasome regulatory subunit RPN10

4

11

Small-scale

0.697

High

771359

POC4
Proteasome chaperone 4

1

1

Small-scale

0.691

High

771356

RPN8
26S proteasome regulatory subunit RPN8

4

16

Small-scale

0.691

High

771360

RPN5
26S proteasome regulatory subunit RPN5

4

20

Small-scale

0.691

High

691476

RPN12
26S proteasome regulatory subunit RPN12

3

5

High-throughput

0.662

High

771337

UBP6
Ubiquitin carboxyl-terminal hydrolase 6

3

11

High-throughput

0.662

High

632490

PSB3
Proteasome subunit beta type-3

1

20

High-throughput

0.618

High

703803

PRS6B
26S proteasome regulatory subunit 6B homolog

1

20

High-throughput

0.618

High

703907

PRS7
26S proteasome regulatory subunit 7 homolog

1

20

High-throughput

0.618

High

771330

PSA6
Proteasome subunit alpha type-6

1

18

High-throughput

0.618

High

771332

PRS4
26S proteasome regulatory subunit 4 homolog

1

20

High-throughput

0.618

High

771342

PRS10
26S proteasome subunit RPT4

1

20

High-throughput

0.618

High

771348

PRS8
26S proteasome regulatory subunit 8 homolog

1

20

High-throughput

0.618

High

771361

RPN6
26S proteasome regulatory subunit RPN6

1

20

High-throughput

0.618

High

771352

RPN9
26S proteasome regulatory subunit RPN9

2

11

High-throughput

0.611

High

687950

IMB3
Importin subunit beta-3

2

0

High-throughput

0.595

High

693310

RPN2
26S proteasome regulatory subunit RPN2

2

20

Small-scale

0.595

High

636227

FUB1
Silencing boundary-establishment protein FUB1

3

1

Small-scale

0.585

High

753402

ECM29
Proteasome component ECM29

2

9

High-throughput

0.584

High

753832

RPN1
26S proteasome regulatory subunit RPN1

2

20

Small-scale

0.584

High

732089

SHE2
SWI5-dependent HO expression protein 2

2

0

High-throughput

0.565

High

771353

POC1
Proteasome chaperone 1

1

1

High-throughput

0.553

High

771355

SUB2
ATP-dependent RNA helicase SUB2

1

4

Small-scale

0.541

High

771351

GCN5
Histone acetyltransferase GCN5

1

7

High-throughput

0.536

High

771340

VPS4
Vacuolar protein sorting-associated protein 4

1

20

Small-scale

0.528

High

604685

RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5

1

1

High-throughput

0.515

High

618840

PP2A2
Serine/threonine-protein phosphatase PP2A-2 catalytic subunit

1

1

High-throughput

0.515

High

628123

SIS1
Protein SIS1

1

4

High-throughput

0.515

High

771341

SGF73
SAGA-associated factor 73

1

0

High-throughput

0.513

High

771363

SUS1
Transcription and mRNA export factor SUS1

1

0

High-throughput

0.513

High

667589

MCM2
DNA replication licensing factor MCM2

1

3

High-throughput

0.508

High

771346

CTF4
DNA polymerase alpha-binding protein

1

3

High-throughput

0.508

High

713695

NOT4
General negative regulator of transcription subunit 4

1

2

High-throughput

0.501

High

771343

BRE5
UBP3-associated protein BRE5

1

2

High-throughput

0.489

High

753593

YAP3
AP-1-like transcription factor YAP3

1

0

High-throughput

0.486

High

771339

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.486

High

771347

GCR2
Glycolytic genes transcriptional activator GCR2

1

0

High-throughput

0.486

High

771349

ADA2
Transcriptional adapter 2

1

0

High-throughput

0.486

High

771357

RDR1
Protein RDR1

1

0

High-throughput

0.486

High

141851

RPN13
26S proteasome regulatory subunit RPN13

1

1

High-throughput

0.479

High

606029

RAD53
Serine/threonine-protein kinase RAD53

1

1

High-throughput

0.479

High

662382

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.479

High

697090

RAD23
UV excision repair protein RAD23

1

20

High-throughput

0.479

High

730816

CENPA
Histone H3-like centromeric protein CSE4

1

4

High-throughput

0.479

High

766856

RPN3
26S proteasome regulatory subunit RPN3

1

7

High-throughput

0.479

High

771344

APJ1
J domain-containing protein APJ1

1

5

High-throughput

0.479

High

771345

H3
Histone H3

1

4

High-throughput

0.479

High

771350

TOM1
E3 ubiquitin-protein ligase TOM1

1

10

High-throughput

0.479

High

771354

RPN7
26S proteasome regulatory subunit RPN7

1

20

High-throughput

0.479

High

771358

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

1

High-throughput

0.479

High

771362

CMR1
DNA damage-binding protein CMR1

1

2

High-throughput

0.479

High

294129

SEM1
26S proteasome complex subunit SEM1

1

0

High-throughput

0.458

High

549058

TRM1
tRNA

1

0

High-throughput

0.458

High

566182

EST1
Telomere elongation protein EST1

1

0

High-throughput

0.458

High

688267

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

715342

SPT7
Transcriptional activator SPT7

1

2

High-throughput

0.445

High

754452

SSZ1
Ribosome-associated complex subunit SSZ1

1

6

High-throughput

0.445

High

768567

SSB2
Ribosome-associated molecular chaperone SSB2

1

6

High-throughput

0.445

High

543840

HSC82
ATP-dependent molecular chaperone HSC82

1

2

High-throughput

0.437

High

745686

NU170
Nucleoporin NUP170

1

1

High-throughput

0.437

High

755047

PP2C7
Protein phosphatase 2C homolog 7, mitochondrial

1

1

High-throughput

0.437

High

771333

MLP2
Protein MLP2

1

2

High-throughput

0.437

High

771338

TCPQ
T-complex protein 1 subunit theta

1

2

High-throughput

0.407

High

613123

URE2
Transcriptional regulator URE2

1

0

High-throughput

0.265

Low

771334

BNI1
Protein BNI1

1

0

High-throughput

0.261

Low

762254

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

546239

CATA
Peroxisomal catalase A

1

0

High-throughput

0.238

Low


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Last updated: 15 Jul 2024