Protein: RCL1
RNA 3'-terminal phosphate cyclase-like protein

Gene: RCL1
Organism: Saccharomyces cerevisiae S288C
Interactions: 134
UniProt ID: Q08096

Gene Ontology (top 5):
GO:0000447 - endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000472 - endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000479 - endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000480 - endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0004521 - RNA endonuclease activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

993370

BMS1
Ribosome biogenesis protein BMS1

10

2

Small-scale

0.756

High

993364

RCL1
RNA 3'-terminal phosphate cyclase-like protein

2

0

High-throughput

0.736

High

748722

ENP1
Essential nuclear protein 1

8

0

Small-scale

0.714

High

979051

DHR1
Probable ATP-dependent RNA helicase DHR1

6

0

Small-scale

0.695

High

792606

UTP10
U3 small nucleolar RNA-associated protein 10

5

0

High-throughput

0.678

High

987609

RRP9
Ribosomal RNA-processing protein 9

3

2

High-throughput

0.656

High

993383

NOP14
Nucleolar complex protein 14

3

1

High-throughput

0.656

High

987669

NOC4
Nucleolar complex protein 4

4

0

Small-scale

0.648

High

635658

PWP2
Periodic tryptophan protein 2

3

1

Small-scale

0.640

High

715995

UTP20
U3 small nucleolar RNA-associated protein 20

3

0

High-throughput

0.628

High

993373

RRP6
Exosome complex exonuclease RRP6

3

0

High-throughput

0.613

High

756800

UTP9
U3 small nucleolar RNA-associated protein 9

2

0

High-throughput

0.585

High

775398

FAF1
Protein FAF1

2

0

Small-scale

0.585

High

991540

NOP6
Nucleolar protein 6

2

0

High-throughput

0.585

High

985823

UTP21
U3 small nucleolar RNA-associated protein 21

2

3

Small-scale

0.584

High

988645

UTP4
U3 small nucleolar RNA-associated protein 4

2

2

Small-scale

0.584

High

993380

NOP58
Nucleolar protein 58

2

1

High-throughput

0.584

High

768125

LCP5
U3 small nucleolar ribonucleoprotein protein LCP5

2

0

Small-scale

0.576

High

982895

RRP5
rRNA biogenesis protein RRP5

2

0

Small-scale

0.569

High

480916

RS8A
Small ribosomal subunit protein eS8A

2

0

High-throughput

0.559

High

630551

RRP7
Ribosomal RNA-processing protein 7

2

0

High-throughput

0.559

High

634794

KRR1
KRR1 small subunit processome component

2

0

High-throughput

0.559

High

784531

DIM1
Dimethyladenosine transferase

2

0

Small-scale

0.559

High

865427

CSL4
Exosome complex component CSL4

2

0

High-throughput

0.559

High

866068

NAT10
RNA cytidine acetyltransferase

2

0

High-throughput

0.559

High

979730

UTP14
U3 small nucleolar RNA-associated protein 14

2

0

High-throughput

0.559

High

512962

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.536

High

492626

HSP71
Heat shock protein SSA1

2

1

High-throughput

0.533

High

549514

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

2

Small-scale

0.515

High

971712

RNT1
Ribonuclease 3

1

0

High-throughput

0.493

High

676426

XPO1
Exportin-1

1

2

High-throughput

0.489

High

141552

RS9A
Small ribosomal subunit protein uS4A

1

1

High-throughput

0.479

High

426181

RS19A
Small ribosomal subunit protein eS19A

1

1

High-throughput

0.479

High

480348

RS6A
Small ribosomal subunit protein eS6A

1

1

High-throughput

0.479

High

481562

RS11B
Small ribosomal subunit protein uS17B

1

1

High-throughput

0.479

High

593713

DBP4
ATP-dependent RNA helicase HCA4

1

1

High-throughput

0.479

High

700106

IMP3
U3 small nucleolar ribonucleoprotein protein IMP3

1

1

High-throughput

0.479

High

753190

DBP8
ATP-dependent RNA helicase DBP8

1

1

High-throughput

0.479

High

755004

RRP4
Exosome complex component RRP4

1

1

High-throughput

0.479

High

799868

ROK1
ATP-dependent RNA helicase ROK1

1

1

High-throughput

0.479

High

809595

RRP41
Exosome complex component SKI6

1

2

High-throughput

0.479

High

810931

MTR4
ATP-dependent RNA helicase DOB1

1

2

High-throughput

0.479

High

860818

RRP46
Exosome complex component RRP46

1

2

High-throughput

0.479

High

973686

UTP17
NET1-associated nuclear protein 1

1

3

High-throughput

0.479

High

975846

TOM1
E3 ubiquitin-protein ligase TOM1

1

1

High-throughput

0.479

High

978641

UTP5
U3 small nucleolar RNA-associated protein 5

1

1

High-throughput

0.479

High

984316

RRP45
Exosome complex component RRP45

1

2

High-throughput

0.479

High

985429

UTP13
U3 small nucleolar RNA-associated protein 13

1

2

High-throughput

0.479

High

988477

BFR2
Protein BFR2

1

1

High-throughput

0.479

High

993375

UTP12
U3 small nucleolar RNA-associated protein 12

1

3

High-throughput

0.479

High

993376

RRP42
Exosome complex component RRP42

1

2

High-throughput

0.479

High

993378

NOP56
Nucleolar protein 56

1

1

High-throughput

0.479

High

408155

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.458

High

413736

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.458

High

479833

RS4A
Small ribosomal subunit protein eS4A

1

0

High-throughput

0.458

High

482488

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.458

High

630275

RRP43
Exosome complex component RRP43

1

0

High-throughput

0.458

High

632121

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.458

High

645685

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.458

High

655907

GAR1
H/ACA ribonucleoprotein complex subunit GAR1

1

0

Small-scale

0.458

High

665084

BMH1
Protein BMH1

1

0

High-throughput

0.458

High

688461

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

706522

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.458

High

707150

DCA13
Protein SOF1

1

0

High-throughput

0.458

High

711082

UTP11
U3 small nucleolar RNA-associated protein 11

1

0

High-throughput

0.458

High

733612

RL1D1
Ribosome biogenesis protein UTP30

1

0

High-throughput

0.458

High

755208

LRP1
Exosome complex protein LRP1

1

0

High-throughput

0.458

High

758481

RRP8
25S rRNA

1

0

High-throughput

0.458

High

767432

UTP7
U3 small nucleolar RNA-associated protein 7

1

0

High-throughput

0.458

High

772689

UTP18
U3 small nucleolar RNA-associated protein 18

1

0

High-throughput

0.458

High

774288

RRT14
Regulator of rDNA transcription protein 14

1

0

High-throughput

0.458

High

774759

UTP25
U3 small nucleolar RNA-associated protein 25

1

0

High-throughput

0.458

High

811569

MPP10
U3 small nucleolar RNA-associated protein MPP10

1

0

High-throughput

0.458

High

816916

NOL10
Ribosome biogenesis protein ENP2

1

0

High-throughput

0.458

High

816981

MTR3
Exosome complex component MTR3

1

0

High-throughput

0.458

High

820206

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

860756

UTP22
U3 small nucleolar RNA-associated protein 22

1

0

High-throughput

0.458

High

861040

UTP8
U3 small nucleolar RNA-associated protein 8

1

0

High-throughput

0.458

High

864743

ESF2
Pre-rRNA-processing protein ESF2

1

0

High-throughput

0.458

High

866626

IMP4
U3 small nucleolar ribonucleoprotein protein IMP4

1

0

High-throughput

0.458

High

970478

UTP6
U3 small nucleolar RNA-associated protein 6

1

0

High-throughput

0.458

High

979252

UTP15
U3 small nucleolar RNA-associated protein 15

1

0

High-throughput

0.458

High

983776

FCF1
rRNA-processing protein FCF1

1

0

High-throughput

0.458

High

986758

NEP1
Ribosomal RNA small subunit methyltransferase NEP1

1

0

High-throughput

0.458

High

987097

ESF1
Pre-rRNA-processing protein ESF1

1

0

High-throughput

0.458

High

992557

CMS1
Protein CMS1

1

0

High-throughput

0.458

High

993365

RRP44
Exosome complex exonuclease DIS3

1

0

High-throughput

0.458

High

993366

RRP40
Exosome complex component RRP40

1

0

High-throughput

0.458

High

993368

UTP16
U3 small nucleolar RNA-associated protein 16

1

0

High-throughput

0.458

High

993371

FCF2
rRNA-processing protein FCF2

1

0

High-throughput

0.458

High

993372

SAS10
Something about silencing protein 10

1

0

High-throughput

0.458

High

993379

RRP36
rRNA biogenesis protein RRP36

1

0

High-throughput

0.458

High

993381

RRP12
Ribosomal RNA-processing protein 12

1

0

High-throughput

0.458

High

993382

EFG1P
rRNA-processing protein EFG1

1

0

High-throughput

0.458

High

993384

PNO1
Pre-rRNA-processing protein PNO1

1

0

High-throughput

0.458

High

769636

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

383380

RL25
Large ribosomal subunit protein uL23

1

1

High-throughput

0.437

High

405860

RL26A
Large ribosomal subunit protein uL24A

1

1

High-throughput

0.437

High

902109

H3
Histone H3

1

1

High-throughput

0.437

High

993369

RS10A
Small ribosomal subunit protein eS10A

1

1

High-throughput

0.437

High

733955

RPF2
Ribosome biogenesis protein RPF2

1

0

High-throughput

0.426

High

495119

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.407

High

695655

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.407

High

366988

HSP82
ATP-dependent molecular chaperone HSP82

2

0

High-throughput

0.298

High

993377

SMT3
Ubiquitin-like protein SMT3

1

0

High-throughput

0.288

High

961960

AP1M1
AP-1 complex subunit mu-1-I

1

0

High-throughput

0.279

Low

977632

VHS1
Serine/threonine-protein kinase VHS1

1

0

High-throughput

0.279

Low

356761

H4
Histone H4

1

0

High-throughput

0.249

Low

358287

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.249

Low

392590

H2A2
Histone H2A.2

1

0

High-throughput

0.249

Low

408482

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

0

High-throughput

0.249

Low

471286

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.249

Low

472423

RL31A
Large ribosomal subunit protein eL31A

1

0

High-throughput

0.249

Low

637166

CYPC
Peptidyl-prolyl cis-trans isomerase C, mitochondrial

1

0

High-throughput

0.249

Low

663494

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

731617

EAP1
Protein EAP1

1

0

High-throughput

0.249

Low

743028

GBLP
Small ribosomal subunit protein RACK1

1

0

High-throughput

0.249

Low

745911

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

752701

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.249

Low

762617

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

860397

EIF2A
Eukaryotic translation initiation factor 2A

1

0

High-throughput

0.249

Low

967793

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.249

Low

978328

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.249

Low

986262

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.249

Low

987055

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.249

Low

991306

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.249

Low

993367

SGO1
Shugoshin

1

0

High-throughput

0.249

Low

993374

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.249

Low

696597

SEC17
Alpha-soluble NSF attachment protein

1

0

High-throughput

0.238

Low

629064

SCJ1
DnaJ-related protein SCJ1

1

0

High-throughput

0.232

Low

705731

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.232

Low

810182

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.232

Low

837368

IMDH3
Inosine-5'-monophosphate dehydrogenase 3

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024