Protein: S10A4
Protein S100-A4 (Calvasculin) (Metastasin) (Placental calcium-binding protein) (Protein Mts1) (S100 calcium-binding protein A4)

Gene: S10A4, S100A4
Organism: Homo sapiens
Interactions: 134
UniProt ID: P26447

Gene Ontology (top 5):
GO:0001837 - epithelial to mesenchymal transition
GO:0003723 - RNA binding
GO:0003779 - actin binding
GO:0005509 - calcium ion binding
GO:0005576 - extracellular region

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

386137

P53
Cellular tumor antigen p53

7

15

Small-scale

0.971

High

380739

S100B
Protein S100-B

5

17

High-throughput

0.935

High

615203

S10A1
Protein S100-A1

4

19

Small-scale

0.907

High

642915

S10A4
Protein S100-A4

2

18

Small-scale

0.823

High

442903

FCG3A
Low affinity immunoglobulin gamma Fc region receptor III-A

1

5

Small-scale

0.740

High

596359

RASA1
Ras GTPase-activating protein 1

2

8

High-throughput

0.737

High

642921

MYH9
Myosin-9

5

13

Small-scale

0.730

High

337962

EGFR
Epidermal growth factor receptor

4

16

Small-scale

0.699

High

416574

S10A6
Protein S100-A6

1

19

High-throughput

0.691

High

642916

S10A2
Protein S100-A2

1

18

High-throughput

0.691

High

642944

RAGE
Advanced glycosylation end product-specific receptor

1

9

Small-scale

0.647

High

642995

CYBP
Calcyclin-binding protein

1

7

Small-scale

0.647

High

548795

AREG
Amphiregulin

2

7

Small-scale

0.619

High

642925

NR2C2
Nuclear receptor subfamily 2 group C member 2

2

5

High-throughput

0.611

High

642962

LIPB1
Liprin-beta-1

2

16

Small-scale

0.611

High

642933

SMAD3
Mothers against decapentaplegic homolog 3

1

4

Small-scale

0.589

High

642935

MDM2
E3 ubiquitin-protein ligase Mdm2

1

9

Small-scale

0.589

High

592107

RAB5A
Ras-related protein Rab-5A

2

4

High-throughput

0.571

High

642917

PEBP1
Phosphatidylethanolamine-binding protein 1

2

3

High-throughput

0.571

High

642942

RIPK1
Receptor-interacting serine/threonine-protein kinase 1

2

1

High-throughput

0.571

High

642923

BAG6
Large proline-rich protein BAG6

1

1

High-throughput

0.541

High

642941

U119A
Protein unc-119 homolog A

1

1

High-throughput

0.541

High

546937

EZRI
Ezrin

1

5

Small-scale

0.536

High

601812

ERBB3
Receptor tyrosine-protein kinase erbB-3

1

16

Small-scale

0.536

High

642919

BTC
Probetacellulin [Cleaved into: Betacellulin

1

7

Small-scale

0.536

High

642945

ERBB4
Receptor tyrosine-protein kinase erbB-4

1

15

Small-scale

0.536

High

161624

GAK
Cyclin-G-associated kinase

1

7

High-throughput

0.536

High

204292

MS18B
Protein Mis18-beta

1

2

High-throughput

0.536

High

214708

SSNA1
Microtubule nucleation factor SSNA1

1

1

High-throughput

0.536

High

257922

DNJB6
DnaJ homolog subfamily B member 6

1

1

High-throughput

0.536

High

309663

KAT7
Histone acetyltransferase KAT7

1

1

High-throughput

0.536

High

319125

BRD1
Bromodomain-containing protein 1

1

4

High-throughput

0.536

High

330547

ZBED1
E3 SUMO-protein ligase ZBED1

1

3

High-throughput

0.536

High

555301

H2AX
Histone H2AX

1

3

High-throughput

0.536

High

602390

ODBB
2-oxoisovalerate dehydrogenase subunit beta, mitochondrial

1

1

High-throughput

0.536

High

625124

CDK2
Cyclin-dependent kinase 2

1

10

High-throughput

0.536

High

642926

ALR
FAD-linked sulfhydryl oxidase ALR

1

3

High-throughput

0.536

High

642927

DSCR6
Protein ripply3

1

8

High-throughput

0.536

High

642928

CORO7
Coronin-7

1

1

High-throughput

0.536

High

642932

HTRA4
Serine protease HTRA4

1

9

High-throughput

0.536

High

642934

XIAP
E3 ubiquitin-protein ligase XIAP

1

4

High-throughput

0.536

High

642936

SATB1
DNA-binding protein SATB1

1

3

High-throughput

0.536

High

642938

UBE3A
Ubiquitin-protein ligase E3A

1

4

High-throughput

0.536

High

642940

XRCC4
DNA repair protein XRCC4

1

2

High-throughput

0.536

High

642946

PO4F3
POU domain, class 4, transcription factor 3

1

8

High-throughput

0.536

High

642949

STXB2
Syntaxin-binding protein 2

1

1

High-throughput

0.536

High

642952

CE170
Centrosomal protein of 170 kDa

1

3

High-throughput

0.536

High

642953

RPRD2
Regulation of nuclear pre-mRNA domain-containing protein 2

1

5

High-throughput

0.536

High

642954

PKN3
Serine/threonine-protein kinase N3

1

7

High-throughput

0.536

High

642958

MYH14
Myosin-14

1

13

High-throughput

0.536

High

642960

CNTRL
Centriolin

1

17

High-throughput

0.536

High

642961

ZFHX4
Zinc finger homeobox protein 4

1

3

High-throughput

0.536

High

642963

KI18B
Kinesin-like protein KIF18B

1

8

High-throughput

0.536

High

642965

WDFY3
WD repeat and FYVE domain-containing protein 3

1

4

High-throughput

0.536

High

642968

AFG2A
ATPase family gene 2 protein homolog A

1

2

High-throughput

0.536

High

642969

SPC24
Kinetochore protein Spc24

1

3

High-throughput

0.536

High

642970

RCBT1
RCC1 and BTB domain-containing protein 1

1

2

High-throughput

0.536

High

642973

SYNE2
Nesprin-2

1

3

High-throughput

0.536

High

642975

PXDN
Peroxidasin homolog

1

2

High-throughput

0.536

High

642978

HAUS1
HAUS augmin-like complex subunit 1

1

3

High-throughput

0.536

High

642979

ESS2
Splicing factor ESS-2 homolog

1

2

High-throughput

0.536

High

642982

VCIP1
Deubiquitinating protein VCPIP1

1

1

High-throughput

0.536

High

642984

PHF12
PHD finger protein 12

1

16

High-throughput

0.536

High

642988

BEX2
Protein BEX2

1

8

High-throughput

0.536

High

642992

TXNIP
Thioredoxin-interacting protein

1

5

High-throughput

0.536

High

642993

HAUS4
HAUS augmin-like complex subunit 4

1

2

High-throughput

0.536

High

642994

COE2
Transcription factor COE2

1

1

High-throughput

0.536

High

642996

SPC25
Kinetochore protein Spc25

1

3

High-throughput

0.536

High

642997

DIAP3
Protein diaphanous homolog 3

1

3

High-throughput

0.536

High

643000

SATB2
DNA-binding protein SATB2

1

3

High-throughput

0.536

High

643001

NDK7
Nucleoside diphosphate kinase homolog 7

1

2

High-throughput

0.536

High

388237

HSPB1
Heat shock protein beta-1

1

0

High-throughput

0.518

High

455109

PARP1
Poly [ADP-ribose] polymerase 1

1

4

High-throughput

0.515

High

642922

MATR3
Matrin-3

1

1

High-throughput

0.515

High

642948

SMAD2
Mothers against decapentaplegic homolog 2

1

4

Small-scale

0.515

High

147315

DPYL4
Dihydropyrimidinase-related protein 4

1

0

High-throughput

0.513

High

203629

SUV91
Histone-lysine N-methyltransferase SUV39H1

1

0

High-throughput

0.513

High

267271

HSBP1
Heat shock factor-binding protein 1

1

0

High-throughput

0.513

High

319434

RPP29
Ribonuclease P protein subunit p29

1

0

High-throughput

0.513

High

474792

POTEI
POTE ankyrin domain family member I

1

0

High-throughput

0.513

High

505700

UMPS
Uridine 5'-monophosphate synthase

1

0

High-throughput

0.513

High

642930

DYL1
Dynein light chain 1, cytoplasmic

1

0

High-throughput

0.513

High

642943

NPAT
Protein NPAT

1

0

High-throughput

0.513

High

642951

ESCO2
N-acetyltransferase ESCO2

1

0

High-throughput

0.513

High

642955

PATE2
Prostate and testis expressed protein 2

1

0

High-throughput

0.513

High

642966

FA24B
Protein FAM24B

1

0

High-throughput

0.513

High

642980

DNJA3
DnaJ homolog subfamily A member 3, mitochondrial

1

0

High-throughput

0.513

High

642985

CRBN
Protein cereblon

1

0

High-throughput

0.513

High

642991

GAN
Gigaxonin

1

0

High-throughput

0.513

High

642924

CCN3
CCN family member 3

1

0

Small-scale

0.504

High

351132

EGF
Pro-epidermal growth factor

1

1

Small-scale

0.501

High

352870

IFNB
Interferon beta

1

6

Small-scale

0.501

High

642918

NAC1
Sodium/calcium exchanger 1

1

18

Small-scale

0.501

High

642931

SRPK2
SRSF protein kinase 2

1

11

High-throughput

0.501

High

642937

NRG1
Pro-neuregulin-1, membrane-bound isoform

1

3

Small-scale

0.501

High

642947

KS6A1
Ribosomal protein S6 kinase alpha-1

1

10

Small-scale

0.501

High

642957

RHOU
Rho-related GTP-binding protein RhoU

1

10

High-throughput

0.501

High

642972

TRPM4
Transient receptor potential cation channel subfamily M member 4

1

12

Small-scale

0.501

High

642983

CEP20
Centrosomal protein 20

1

5

Small-scale

0.501

High

642986

HBEGF
Proheparin-binding EGF-like growth factor [Cleaved into: Heparin-binding EGF-like growth factor

1

7

Small-scale

0.501

High

59112

VWA8
von Willebrand factor A domain-containing protein 8

1

1

High-throughput

0.489

High

307243

RCBT2
RCC1 and BTB domain-containing protein 2

1

2

High-throughput

0.489

High

520689

ODBA
2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial

1

2

High-throughput

0.489

High

642939

GOGA2
Golgin subfamily A member 2

1

16

High-throughput

0.489

High

642950

CCD14
Coiled-coil domain-containing protein 14

1

3

High-throughput

0.489

High

642956

CE128
Centrosomal protein of 128 kDa

1

18

High-throughput

0.489

High

642959

TT21B
Tetratricopeptide repeat protein 21B

1

2

High-throughput

0.489

High

642964

CC28A
Coiled-coil domain-containing protein 28A

1

4

High-throughput

0.489

High

642976

SIA7F
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6

1

5

High-throughput

0.489

High

642981

VPS39
Vam6/Vps39-like protein

1

3

High-throughput

0.489

High

642987

CC28B
Coiled-coil domain-containing protein 28B

1

4

High-throughput

0.489

High

642989

CEP44
Centrosomal protein of 44 kDa

1

1

High-throughput

0.489

High

642990

VPS11
Vacuolar protein sorting-associated protein 11 homolog

1

2

High-throughput

0.489

High

205066

TGON2
Trans-Golgi network integral membrane protein 2

1

1

High-throughput

0.479

High

243963

BRD4
Bromodomain-containing protein 4

1

5

High-throughput

0.479

High

300528

NFAT5
Nuclear factor of activated T-cells 5

1

2

Small-scale

0.479

High

352500

TNFA
Tumor necrosis factor

1

5

High-throughput

0.479

High

373708

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

10

High-throughput

0.479

High

580609

ML12A
Myosin regulatory light chain 12A

1

1

High-throughput

0.479

High

590634

BTF3
Transcription factor BTF3

1

2

High-throughput

0.479

High

642929

RHOA
Transforming protein RhoA

1

7

Small-scale

0.479

High

642971

CEP76
Centrosomal protein of 76 kDa

1

1

High-throughput

0.479

High

642974

BBX
HMG box transcription factor BBX

1

8

High-throughput

0.479

High

642977

CHM4C
Charged multivesicular body protein 4c

1

6

High-throughput

0.479

High

642998

HDAC6
Histone deacetylase 6

1

8

High-throughput

0.479

High

562509

IL7RA
Interleukin-7 receptor subunit alpha

1

0

High-throughput

0.458

High

87342

C9JA69
BBX high mobility group box domain containing

1

8

High-throughput

0.445

High

159546

ML12B
Myosin regulatory light chain 12B

1

1

High-throughput

0.445

High

642920

BMI1
Polycomb complex protein BMI-1

1

12

High-throughput

0.445

High

642967

PTGR2
Prostaglandin reductase 2

1

2

High-throughput

0.437

High

353842

IGHG3
Immunoglobulin heavy constant gamma 3

1

0

High-throughput

0.426

High

102420

G3V3Y1
15-oxoprostaglandin 13-reductase

1

2

High-throughput

0.407

High

642999

QCR9
Cytochrome b-c1 complex subunit 9

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024