Protein: SAS10
Something about silencing protein 10 (U three protein 3) (U3 small nucleolar RNA-associated protein 3) (U3 snoRNA-associated protein 11)

Gene: SAS10
Organism: Saccharomyces cerevisiae S288C
Interactions: 197
UniProt ID: Q12136

Gene Ontology (top 5):
GO:0000447 - endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000462 - maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000472 - endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000480 - endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1015081

RRP6
Exosome complex exonuclease RRP6

2

1

High-throughput

0.754

High

774763

UTP25
U3 small nucleolar RNA-associated protein 25

5

1

Small-scale

0.729

High

811576

MPP10
U3 small nucleolar RNA-associated protein MPP10

5

1

Small-scale

0.723

High

985832

UTP21
U3 small nucleolar RNA-associated protein 21

4

2

Small-scale

0.691

High

979074

DHR1
Probable ATP-dependent RNA helicase DHR1

5

0

Small-scale

0.680

High

987688

NOC4
Nucleolar complex protein 4

5

0

Small-scale

0.680

High

634818

KRR1
KRR1 small subunit processome component

3

1

High-throughput

0.672

High

748741

ENP1
Essential nuclear protein 1

4

0

High-throughput

0.659

High

792625

UTP10
U3 small nucleolar RNA-associated protein 10

4

0

High-throughput

0.659

High

970486

UTP6
U3 small nucleolar RNA-associated protein 6

3

0

Small-scale

0.649

High

1015090

NOP58
Nucleolar protein 58

3

2

Small-scale

0.640

High

593723

DBP4
ATP-dependent RNA helicase HCA4

2

2

High-throughput

0.637

High

700112

IMP3
U3 small nucleolar ribonucleoprotein protein IMP3

2

2

High-throughput

0.637

High

979746

UTP14
U3 small nucleolar RNA-associated protein 14

3

0

High-throughput

0.630

High

1015080

SAS10
Something about silencing protein 10

2

0

Small-scale

0.619

High

635666

PWP2
Periodic tryptophan protein 2

2

2

High-throughput

0.614

High

753196

DBP8
ATP-dependent RNA helicase DBP8

2

1

High-throughput

0.614

High

767441

UTP7
U3 small nucleolar RNA-associated protein 7

2

3

High-throughput

0.614

High

1015089

RRP36
rRNA biogenesis protein RRP36

2

0

High-throughput

0.610

High

1015095

NOP14
Nucleolar complex protein 14

2

0

High-throughput

0.610

High

859456

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

2

1

High-throughput

0.608

High

711089

UTP11
U3 small nucleolar RNA-associated protein 11

2

0

High-throughput

0.588

High

772698

UTP18
U3 small nucleolar RNA-associated protein 18

2

0

High-throughput

0.588

High

799877

ROK1
ATP-dependent RNA helicase ROK1

2

0

High-throughput

0.588

High

860771

UTP22
U3 small nucleolar RNA-associated protein 22

2

0

High-throughput

0.588

High

987106

ESF1
Pre-rRNA-processing protein ESF1

2

0

High-throughput

0.588

High

1015091

SKS1
Serine/threonine-protein kinase SKS1

2

1

High-throughput

0.586

High

775405

FAF1
Protein FAF1

2

0

Small-scale

0.585

High

988654

UTP4
U3 small nucleolar RNA-associated protein 4

2

3

Small-scale

0.584

High

976888

HAS1
ATP-dependent RNA helicase HAS1

1

2

High-throughput

0.582

High

339902

CDK1
Cyclin-dependent kinase 1

2

0

High-throughput

0.569

High

630288

RRP43
Exosome complex component RRP43

2

0

High-throughput

0.559

High

865434

CSL4
Exosome complex component CSL4

2

0

High-throughput

0.559

High

861448

NOP19
Nucleolar protein 19

1

0

High-throughput

0.558

High

730740

DHR2
Probable ATP-dependent RNA helicase DHR2

1

2

High-throughput

0.541

High

753058

RRP3
ATP-dependent rRNA helicase RRP3

1

2

High-throughput

0.541

High

471311

RS22A
Small ribosomal subunit protein uS8A

2

1

High-throughput

0.533

High

745001

DUG2
Probable di- and tripeptidase DUG2

1

0

High-throughput

0.518

High

811373

NOP9
Nucleolar protein 9

1

0

High-throughput

0.518

High

860538

SLX9
Ribosome biogenesis protein SLX9

1

0

High-throughput

0.518

High

865571

SQS1
Protein SQS1

1

0

High-throughput

0.518

High

986078

SGD1
Suppressor of glycerol defect protein 1

1

0

High-throughput

0.518

High

589105

PRP4
U4/U6 small nuclear ribonucleoprotein PRP4

1

1

High-throughput

0.515

High

615195

BUR1
Serine/threonine-protein kinase BUR1

1

1

High-throughput

0.515

High

664563

HRR25
Casein kinase I homolog HRR25

1

0

High-throughput

0.513

High

676462

XPO1
Exportin-1

1

0

High-throughput

0.513

High

733975

RPF2
Ribosome biogenesis protein RPF2

1

0

High-throughput

0.513

High

412913

KAPA
cAMP-dependent protein kinase type 1

1

1

High-throughput

0.501

High

539421

KSS1
Mitogen-activated protein kinase KSS1

1

1

High-throughput

0.501

High

562774

FUS3
Mitogen-activated protein kinase FUS3

1

1

High-throughput

0.501

High

605595

DBF2
Cell cycle protein kinase DBF2

1

2

High-throughput

0.501

High

614853

KC11
Casein kinase I homolog 1

1

2

High-throughput

0.501

High

615092

KC12
Casein kinase I homolog 2

1

2

High-throughput

0.501

High

629526

KIN82
Serine/threonine-protein kinase KIN82

1

1

High-throughput

0.501

High

688842

IRE1
Serine/threonine-protein kinase/endoribonuclease IRE1

1

1

High-throughput

0.501

High

693758

IME2
Meiosis induction protein kinase IME2/SME1

1

2

High-throughput

0.501

High

751098

RCK1
Serine/threonine-protein kinase RCK1

1

1

High-throughput

0.501

High

752241

KSP1
Serine/threonine-protein kinase KSP1

1

2

High-throughput

0.501

High

819918

CLA4
Serine/threonine-protein kinase CLA4

1

2

High-throughput

0.501

High

860327

FMP48
Probable serine/threonine-protein kinase FMP48

1

3

High-throughput

0.501

High

976607

STE20
Serine/threonine-protein kinase STE20

1

2

High-throughput

0.501

High

1015083

GIN4
Serine/threonine-protein kinase GIN4

1

1

High-throughput

0.501

High

1015085

PRR2
Serine/threonine-protein kinase PRR2

1

2

High-throughput

0.501

High

1015088

SKM1
Serine/threonine-protein kinase SKM1

1

2

High-throughput

0.501

High

812512

JHD2
Histone demethylase JHD2

1

0

High-throughput

0.493

High

602781

MCK1
Protein kinase MCK1

1

0

High-throughput

0.480

High

606169

RAD53
Serine/threonine-protein kinase RAD53

1

0

High-throughput

0.480

High

679768

PSK1
Serine/threonine-protein kinase PSK1

1

0

High-throughput

0.480

High

730498

NNK1
Nitrogen network kinase 1

1

0

High-throughput

0.480

High

141576

RS9A
Small ribosomal subunit protein uS4A

1

2

High-throughput

0.479

High

480373

RS6A
Small ribosomal subunit protein eS6A

1

1

High-throughput

0.479

High

480942

RS8A
Small ribosomal subunit protein eS8A

1

1

High-throughput

0.479

High

604637

RPA2
DNA-directed RNA polymerase I subunit RPA135

1

1

High-throughput

0.479

High

606781

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

1

High-throughput

0.479

High

632143

RS2
Small ribosomal subunit protein uS5

1

1

High-throughput

0.479

High

663628

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.479

High

663931

TF3B
Transcription factor IIIB 70 kDa subunit

1

1

High-throughput

0.479

High

700676

RSSA1
Small ribosomal subunit protein uS2A

1

2

High-throughput

0.479

High

707157

DCA13
Protein SOF1

1

1

High-throughput

0.479

High

733616

RL1D1
Ribosome biogenesis protein UTP30

1

1

High-throughput

0.479

High

743054

GBLP
Small ribosomal subunit protein RACK1

1

1

Small-scale

0.479

High

774013

MLP2
Protein MLP2

1

1

High-throughput

0.479

High

809602

RRP41
Exosome complex component SKI6

1

3

High-throughput

0.479

High

810950

MTR4
ATP-dependent RNA helicase DOB1

1

1

High-throughput

0.479

High

860825

RRP46
Exosome complex component RRP46

1

3

High-throughput

0.479

High

864747

ESF2
Pre-rRNA-processing protein ESF2

1

1

High-throughput

0.479

High

973694

UTP17
NET1-associated nuclear protein 1

1

3

High-throughput

0.479

High

978649

UTP5
U3 small nucleolar RNA-associated protein 5

1

2

High-throughput

0.479

High

979261

UTP15
U3 small nucleolar RNA-associated protein 15

1

1

High-throughput

0.479

High

982913

RRP5
rRNA biogenesis protein RRP5

1

1

High-throughput

0.479

High

984324

RRP45
Exosome complex component RRP45

1

3

High-throughput

0.479

High

985439

UTP13
U3 small nucleolar RNA-associated protein 13

1

2

High-throughput

0.479

High

987617

RRP9
Ribosomal RNA-processing protein 9

1

1

High-throughput

0.479

High

993684

RRP44
Exosome complex exonuclease DIS3

1

1

High-throughput

0.479

High

996181

ESA1
Histone acetyltransferase ESA1

1

1

Small-scale

0.479

High

1015082

UTP12
U3 small nucleolar RNA-associated protein 12

1

2

High-throughput

0.479

High

1015084

RRP42
Exosome complex component RRP42

1

3

High-throughput

0.479

High

1015087

NOP56
Nucleolar protein 56

1

2

High-throughput

0.479

High

515023

RNA1
Ran GTPase-activating protein 1

1

0

High-throughput

0.460

High

708073

NUF2
Kinetochore protein NUF2

1

0

High-throughput

0.460

High

777332

SA185
SIT4-associating protein SAP185

1

0

High-throughput

0.460

High

778887

NOP2
25S rRNA

1

0

High-throughput

0.460

High

979648

SPC24
Kinetochore protein SPC24

1

0

High-throughput

0.460

High

407387

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

408179

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.458

High

408494

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

0

High-throughput

0.458

High

413762

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.458

High

482508

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.458

High

628577

SIS1
Protein SIS1

1

0

High-throughput

0.458

High

630558

RRP7
Ribosomal RNA-processing protein 7

1

0

High-throughput

0.458

High

645707

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.458

High

688484

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

706550

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.458

High

716005

UTP20
U3 small nucleolar RNA-associated protein 20

1

0

High-throughput

0.458

High

730169

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.458

High

752724

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.458

High

755011

RRP4
Exosome complex component RRP4

1

0

High-throughput

0.458

High

755215

LRP1
Exosome complex protein LRP1

1

0

High-throughput

0.458

High

756809

UTP9
U3 small nucleolar RNA-associated protein 9

1

0

High-throughput

0.458

High

758487

RRP8
25S rRNA

1

0

High-throughput

0.458

High

768131

LCP5
U3 small nucleolar ribonucleoprotein protein LCP5

1

0

High-throughput

0.458

High

774294

RRT14
Regulator of rDNA transcription protein 14

1

0

High-throughput

0.458

High

775287

ULP2
Ubiquitin-like-specific protease 2

1

0

High-throughput

0.458

High

775893

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.458

High

784539

DIM1
Dimethyladenosine transferase

1

0

Small-scale

0.458

High

816924

NOL10
Ribosome biogenesis protein ENP2

1

0

High-throughput

0.458

High

816988

MTR3
Exosome complex component MTR3

1

0

High-throughput

0.458

High

861048

UTP8
U3 small nucleolar RNA-associated protein 8

1

0

High-throughput

0.458

High

866081

NAT10
RNA cytidine acetyltransferase

1

0

High-throughput

0.458

High

866545

APJ1
J domain-containing protein APJ1

1

0

High-throughput

0.458

High

866635

IMP4
U3 small nucleolar ribonucleoprotein protein IMP4

1

0

High-throughput

0.458

High

872823

ORC1
Origin recognition complex subunit 1

1

0

High-throughput

0.458

High

983782

FCF1
rRNA-processing protein FCF1

1

0

High-throughput

0.458

High

986766

NEP1
Ribosomal RNA small subunit methyltransferase NEP1

1

0

High-throughput

0.458

High

987067

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.458

High

988486

BFR2
Protein BFR2

1

0

High-throughput

0.458

High

992561

CMS1
Protein CMS1

1

0

High-throughput

0.458

High

993372

RCL1
RNA 3'-terminal phosphate cyclase-like protein

1

0

High-throughput

0.458

High

994585

RRP40
Exosome complex component RRP40

1

0

High-throughput

0.458

High

995829

SGO1
Shugoshin

1

0

High-throughput

0.458

High

995872

UTP16
U3 small nucleolar RNA-associated protein 16

1

0

High-throughput

0.458

High

997061

BMS1
Ribosome biogenesis protein BMS1

1

0

High-throughput

0.458

High

1014902

FCF2
rRNA-processing protein FCF2

1

0

High-throughput

0.458

High

1015093

RRP12
Ribosomal RNA-processing protein 12

1

0

High-throughput

0.458

High

1015096

PNO1
Pre-rRNA-processing protein PNO1

1

0

High-throughput

0.458

High

996276

HRK1
Serine/threonine-protein kinase HRK1

1

1

High-throughput

0.457

High

516331

RAP1
DNA-binding protein RAP1

1

0

High-throughput

0.438

High

678209

PUS3
tRNA pseudouridine(38/39) synthase

1

0

High-throughput

0.438

High

693666

SIP1
SNF1 protein kinase subunit beta-1

1

0

High-throughput

0.438

High

810749

NET1
Nucleolar protein NET1

1

0

High-throughput

0.438

High

858802

RMR1
Reduced meiotic recombination protein 1

1

0

High-throughput

0.438

High

996211

TMA16
Translation machinery-associated protein 16

1

0

High-throughput

0.438

High

1015069

MED2
Mediator of RNA polymerase II transcription subunit 2

1

0

High-throughput

0.438

High

383402

RL25
Large ribosomal subunit protein uL23

1

1

High-throughput

0.437

High

426201

RS19A
Small ribosomal subunit protein eS19A

1

1

High-throughput

0.437

High

472447

RL31A
Large ribosomal subunit protein eL31A

1

1

High-throughput

0.437

High

959897

NUM1
Nuclear migration protein NUM1

1

1

High-throughput

0.437

High

996345

RS10A
Small ribosomal subunit protein eS10A

1

1

High-throughput

0.437

High

1015094

RS22B
Small ribosomal subunit protein uS8B

1

1

High-throughput

0.437

High

492780

HSP71
Heat shock protein SSA1

1

0

High-throughput

0.426

High

681074

HS104
Heat shock protein 104

1

0

High-throughput

0.426

High

812685

PMT3
Dolichyl-phosphate-mannose--protein mannosyltransferase 3

1

1

High-throughput

0.417

High

988531

PMT7
Probable dolichyl-phosphate-mannose--protein mannosyltransferase 7

1

1

High-throughput

0.417

High

690389

ERG24
Delta(14)-sterol reductase ERG24

1

0

High-throughput

0.282

High

746655

FAT1
Very long-chain fatty acid transport protein

1

0

High-throughput

0.282

High

699378

UGPA1
UTP--glucose-1-phosphate uridylyltransferase

1

0

High-throughput

0.269

Low

774629

PRK1
Actin-regulating kinase PRK1

1

0

High-throughput

0.261

Low

859161

ATG1
Serine/threonine-protein kinase ATG1

1

0

High-throughput

0.261

Low

968061

KIN4
Serine/threonine-protein kinase KIN4

1

0

High-throughput

0.261

Low

358306

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.249

Low

404735

RL7A
Large ribosomal subunit protein uL30A

1

0

High-throughput

0.249

Low

405880

RL26A
Large ribosomal subunit protein uL24A

1

0

High-throughput

0.249

Low

446248

MYO1
Myosin-1

1

0

Small-scale

0.249

Low

524482

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.249

Low

762659

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

820229

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.249

Low

860412

EIF2A
Eukaryotic translation initiation factor 2A

1

0

High-throughput

0.249

Low

967820

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.249

Low

530140

ATN1
Sodium/potassium exporting P-type ATPase 1

1

0

High-throughput

0.238

Low

635248

HSP30
30 kDa heat shock protein

1

0

High-throughput

0.238

Low

716056

GCS1
ADP-ribosylation factor GTPase-activating protein GCS1

1

0

High-throughput

0.238

Low

809733

GPI2
Phosphatidylinositol N-acetylglucosaminyltransferase GPI2 subunit

1

0

High-throughput

0.238

Low

810316

YJR5
Putative uncharacterized membrane protein YJL175W

1

0

High-throughput

0.238

Low

812029

GPN1
GPN-loop GTPase 1

1

0

High-throughput

0.238

Low

859043

YIP4
Protein YIP4

1

0

High-throughput

0.238

Low

859072

YGT5
Putative 2-hydroxyacid dehydrogenase YGL185C

1

0

High-throughput

0.238

Low

861193

YG3R
Putative uncharacterized protein YGR160W

1

0

High-throughput

0.238

Low

861654

YG61
Putative uncharacterized membrane protein YGR290W

1

0

High-throughput

0.238

Low

866110

ESBP6
Uncharacterized transporter ESBP6

1

0

High-throughput

0.238

Low

953548

YD269
Putative uncharacterized protein YDR269C

1

0

High-throughput

0.238

Low

990775

SSK1
Osmolarity two-component system protein SSK1

1

0

High-throughput

0.238

Low

994540

YOL18
Uncharacterized protein YOL118C

1

0

High-throughput

0.238

Low

1014881

AP1G1
AP-1 complex subunit gamma-1

1

0

High-throughput

0.238

Low

1015086

YO309
Putative uncharacterized protein YOR309C

1

0

High-throughput

0.238

Low

1015092

YO314
Uncharacterized protein YOR314W

1

0

High-throughput

0.238

Low

760982

TCPD
T-complex protein 1 subunit delta

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024