Protein: ITK
Tyrosine-protein kinase ITK/TSK (EC 2.7.10.2) (IL-2-inducible T-cell kinase) (Kinase EMT) (Kinase TLK) (T-cell-specific kinase)

Gene: ITK
Organism: Mus musculus
Interactions: 9
UniProt ID: Q03526

Gene Ontology (top 5):
GO:0001819 - positive regulation of cytokine production
GO:0001865 - NK T cell differentiation
GO:0002250 - adaptive immune response
GO:0004715 - non-membrane spanning protein tyrosine kinase activity
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1043255

LCP2
Lymphocyte cytosolic protein 2

1

20

Small-scale

0.647

High

1043254

PHAG1
Phosphoprotein associated with glycosphingolipid-enriched microdomains 1

1

11

High-throughput

0.618

High

1043258

BLNK
B-cell linker protein

1

20

Small-scale

0.618

High

1043257

ANR54
Ankyrin repeat domain-containing protein 54

1

14

High-throughput

0.590

High

651517

CBL
E3 ubiquitin-protein ligase CBL

1

20

Small-scale

0.479

High

965993

HNRPK
Heterogeneous nuclear ribonucleoprotein K

1

11

High-throughput

0.457

High

1043256

PKHM1
Pleckstrin homology domain-containing family M member 1

1

3

High-throughput

0.457

High

236823

LAT
Linker for activation of T-cells family member 1

1

4

High-throughput

0.445

High

148320

COE3
Transcription factor COE3

1

0

High-throughput

0.438

High


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Last updated: 11Aug2025