Protein: LSP1
Sphingolipid long chain base-responsive protein LSP1

Gene: LSP1
Organism: Saccharomyces cerevisiae S288C
Interactions: 165
UniProt ID: Q12230

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005741 - mitochondrial outer membrane
GO:0005886 - plasma membrane
GO:0006897 - endocytosis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

860643

PIL1
Sphingolipid long chain base-responsive protein PIL1

12

5

Small-scale

0.978

High

1015350

LSP1
Sphingolipid long chain base-responsive protein LSP1

3

5

Small-scale

0.862

High

976285

PKH1
Serine/threonine-protein kinase PKH1

4

4

Small-scale

0.692

High

728014

MRP8
Uncharacterized protein MRP8

4

1

High-throughput

0.687

High

979226

SEG1
Eisosome protein SEG1

4

3

Small-scale

0.683

High

1015351

PKH2
Serine/threonine-protein kinase PKH2

3

4

Small-scale

0.664

High

861131

YG3A
Uncharacterized protein YGR130C

3

1

Small-scale

0.658

High

983028

EIS1
Eisosome protein 1

3

1

Small-scale

0.650

High

605182

XRN1
5'-3' exoribonuclease 1

3

1

High-throughput

0.643

High

696102

HSP79
Heat shock protein homolog SSE2

2

6

High-throughput

0.608

High

771776

TBP6
Probable 26S proteasome subunit YTA6

2

5

High-throughput

0.606

High

628589

SIS1
Protein SIS1

3

1

High-throughput

0.597

High

681082

HS104
Heat shock protein 104

2

3

High-throughput

0.584

High

797640

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

1

High-throughput

0.584

High

705804

HSP78
Heat shock protein 78, mitochondrial

2

3

High-throughput

0.571

High

784448

COPB2
Coatomer subunit beta'

2

2

Small-scale

0.561

High

769793

SSB2
Ribosome-associated molecular chaperone SSB2

2

3

High-throughput

0.552

High

622090

SSD1
Protein SSD1

1

1

High-throughput

0.541

High

643214

PPZ1
Serine/threonine-protein phosphatase PP-Z1

1

1

High-throughput

0.541

High

765912

DLD3
D-2-hydroxyglutarate--pyruvate transhydrogenase DLD3

1

1

High-throughput

0.541

High

872775

ALO
D-arabinono-1,4-lactone oxidase

1

1

High-throughput

0.541

High

1015352

TPO4
Polyamine transporter 4

1

4

High-throughput

0.541

High

760984

TCPD
T-complex protein 1 subunit delta

2

2

High-throughput

0.537

High

492829

HSP71
Heat shock protein SSA1

1

3

High-throughput

0.536

High

664569

HRR25
Casein kinase I homolog HRR25

1

1

High-throughput

0.536

High

865471

ELOA1
Elongin-A

1

1

High-throughput

0.536

High

978088

VPS64
Vacuolar protein sorting-associated protein 64

1

1

High-throughput

0.536

High

980199

SEN15
tRNA-splicing endonuclease subunit SEN15

1

1

High-throughput

0.536

High

587282

HNM1
Choline transport protein

1

0

High-throughput

0.518

High

731448

MID2
Cell wall integrity sensor MID2

1

0

High-throughput

0.518

High

767048

EDC2
Enhancer of mRNA-decapping protein 2

1

0

High-throughput

0.518

High

810797

BNA3
Probable kynurenine--oxoglutarate transaminase BNA3

1

0

High-throughput

0.518

High

838491

MUP1
High-affinity methionine permease

1

0

High-throughput

0.518

High

1015356

LSO2
Protein LSO2

1

0

High-throughput

0.518

High

629304

HAL4
Serine/threonine-protein kinase HAL4/SAT4

1

3

High-throughput

0.515

High

687856

MSS51
Protein MSS51, mitochondrial

1

1

High-throughput

0.515

High

691604

EIF3C
Eukaryotic translation initiation factor 3 subunit C

1

1

High-throughput

0.515

High

696761

RTG2
Retrograde regulation protein 2

1

1

High-throughput

0.515

High

713185

FAB1
1-phosphatidylinositol 3-phosphate 5-kinase FAB1

1

1

High-throughput

0.515

High

857413

VPS4
Vacuolar protein sorting-associated protein 4

1

5

High-throughput

0.515

High

859592

MLC1
Myosin light chain 1

1

1

High-throughput

0.515

High

964746

BCK1
Serine/threonine-protein kinase BCK1/SLK1/SSP31

1

1

High-throughput

0.515

High

986664

YL179
Uncharacterized protein YLR179C

1

2

High-throughput

0.515

High

986770

NEP1
Ribosomal RNA small subunit methyltransferase NEP1

1

0

High-throughput

0.513

High

479548

RS24A
Small ribosomal subunit protein eS24A

1

1

High-throughput

0.508

High

984818

MSC3
Meiotic sister-chromatid recombination protein 3

1

1

High-throughput

0.508

High

618249

AATC
Aspartate aminotransferase, cytoplasmic

1

1

High-throughput

0.494

High

687509

EF2
Elongation factor 2

1

1

High-throughput

0.494

High

748564

ARPC1
Actin-related protein 2/3 complex subunit 1

1

2

High-throughput

0.494

High

867507

PUR91
Bifunctional purine biosynthesis protein ADE16 [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase

1

2

High-throughput

0.494

High

618805

PP2A1
Serine/threonine-protein phosphatase PP2A-1 catalytic subunit

1

0

High-throughput

0.493

High

640862

CDC20
APC/C activator protein CDC20

1

0

High-throughput

0.493

High

660079

KIP2
Kinesin-like protein KIP2

1

0

High-throughput

0.493

High

686221

GLPK
Glycerol kinase

1

0

High-throughput

0.493

High

689841

RIM1
Single-stranded DNA-binding protein RIM1, mitochondrial

1

0

High-throughput

0.493

High

984758

POC1
Proteasome chaperone 1

1

0

High-throughput

0.493

High

419586

RAD1
DNA repair protein RAD1

1

1

High-throughput

0.489

High

1015150

YP150
Putative serine/threonine-protein kinase YPL150W

1

3

High-throughput

0.489

High

336272

CCPR
Cytochrome c peroxidase, mitochondrial

1

0

High-throughput

0.486

High

697599

KA122
Importin beta-like protein KAP122

1

1

Small-scale

0.481

High

141583

RS9A
Small ribosomal subunit protein uS4A

1

2

High-throughput

0.479

High

407395

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.479

High

408185

RS13
Small ribosomal subunit protein uS15

1

1

High-throughput

0.479

High

478611

HSP77
Import motor subunit, mitochondrial

1

2

High-throughput

0.479

High

482514

RS18A
Small ribosomal subunit protein uS13A

1

1

High-throughput

0.479

High

604905

GAS1
1,3-beta-glucanosyltransferase GAS1

1

1

High-throughput

0.479

High

629911

YCP4
Flavoprotein-like protein YCP4

1

3

High-throughput

0.479

High

632148

RS2
Small ribosomal subunit protein uS5

1

1

High-throughput

0.479

High

665113

BMH1
Protein BMH1

1

2

High-throughput

0.479

High

692645

ZUO1
Zuotin

1

1

Small-scale

0.479

High

700021

TIM23
Mitochondrial import inner membrane translocase subunit TIM23

1

1

High-throughput

0.479

High

711155

SEG2
Eisosome protein SEG2

1

3

High-throughput

0.479

High

730175

RS27A
Small ribosomal subunit protein eS27A

1

2

High-throughput

0.479

High

732987

MIC60
MICOS complex subunit MIC60

1

1

High-throughput

0.479

High

743059

GBLP
Small ribosomal subunit protein RACK1

1

1

High-throughput

0.479

High

746967

ECM33
Cell wall protein ECM33

1

1

High-throughput

0.479

High

748200

AIM4
Altered inheritance of mitochondria protein 4

1

1

High-throughput

0.479

High

752730

RS20
Small ribosomal subunit protein uS10

1

1

High-throughput

0.479

High

756605

KOG1
Target of rapamycin complex 1 subunit KOG1

1

1

Small-scale

0.479

High

762668

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.479

High

765432

RSP5
E3 ubiquitin-protein ligase RSP5

1

3

High-throughput

0.479

High

775537

INP51
Phosphatidylinositol 4,5-bisphosphate 5-phosphatase INP51

1

1

Small-scale

0.479

High

810250

ATG27
Autophagy-related protein 27

1

1

High-throughput

0.479

High

820235

RS12
Small ribosomal subunit protein eS12

1

1

High-throughput

0.479

High

826219

TOM22
Mitochondrial import receptor subunit TOM22

1

1

High-throughput

0.479

High

865329

GIS2
Zinc finger protein GIS2

1

1

High-throughput

0.479

High

866812

SAM50
Sorting assembly machinery 50 kDa subunit

1

1

High-throughput

0.479

High

962646

ACAC
Acetyl-CoA carboxylase

1

2

Small-scale

0.479

High

967826

RS15
Small ribosomal subunit protein uS19

1

1

High-throughput

0.479

High

975868

TOM1
E3 ubiquitin-protein ligase TOM1

1

3

High-throughput

0.479

High

982712

COX20
Cytochrome c oxidase assembly protein COX20, mitochondrial

1

1

High-throughput

0.479

High

982805

RTN1
Reticulon-like protein 1

1

1

Small-scale

0.479

High

1015100

ATG9
Autophagy-related protein 9

1

1

High-throughput

0.479

High

1015353

PST2
Protoplast secreted protein 2

1

3

High-throughput

0.479

High

1015355

LAS17
Proline-rich protein LAS17

1

1

Small-scale

0.479

High

747569

AIM3
Altered inheritance of mitochondria protein 3

1

1

High-throughput

0.470

High

846321

RL9B
Large ribosomal subunit protein uL6B

1

2

High-throughput

0.470

High

987364

CORO
Coronin-like protein

1

1

High-throughput

0.470

High

470693

RS25B
Small ribosomal subunit protein eS25B

1

2

High-throughput

0.464

High

810686

TAX4
Protein TAX4

1

1

High-throughput

0.464

High

1015354

DBP10
ATP-dependent RNA helicase DBP10

1

2

High-throughput

0.464

High

1015357

RS25A
Small ribosomal subunit protein eS25A

1

2

High-throughput

0.464

High

541822

SEC63
Protein translocation protein SEC63

1

0

Small-scale

0.460

High

865703

RHO5
GTP-binding protein RHO5

1

0

Small-scale

0.460

High

630293

RRP43
Exosome complex component RRP43

1

0

High-throughput

0.458

High

701820

YPT7
Ypt/Rab-type GTPase YPT7

1

0

Small-scale

0.458

High

747096

IST2
Increased sodium tolerance protein 2

1

0

High-throughput

0.458

High

858962

MDM34
Mitochondrial distribution and morphology protein 34

1

0

Small-scale

0.458

High

675028

ITR1
Myo-inositol transporter 1

1

3

High-throughput

0.457

High

340318

KPYK1
Pyruvate kinase 1

1

1

High-throughput

0.445

High

495294

HSP72
Heat shock protein SSA2

1

3

High-throughput

0.445

High

513189

SSB1
Ribosome-associated molecular chaperone SSB1

1

3

High-throughput

0.445

High

544594

HSC82
ATP-dependent molecular chaperone HSC82

1

2

High-throughput

0.445

High

556377

VATB
V-type proton ATPase subunit B

1

2

High-throughput

0.445

High

695796

HSP7F
Heat shock protein homolog SSE1

1

6

High-throughput

0.445

High

767987

SCS2
Vesicle-associated membrane protein-associated protein SCS2

1

1

High-throughput

0.445

High

773791

6P21
6-phosphofructo-2-kinase 1

1

2

High-throughput

0.445

High

481444

RL2A
Large ribosomal subunit protein uL2A

1

1

High-throughput

0.439

High

791240

ZIM17
Mitochondrial protein import protein ZIM17

1

0

High-throughput

0.438

High

986339

YL326
Uncharacterized membrane protein YLR326W

1

0

High-throughput

0.438

High

358313

RS17A
Small ribosomal subunit protein eS17A

1

2

High-throughput

0.437

High

383410

RL25
Large ribosomal subunit protein uL23

1

1

High-throughput

0.437

High

405886

RL26A
Large ribosomal subunit protein uL24A

1

1

High-throughput

0.437

High

413769

RS14A
Small ribosomal subunit protein uS11A

1

2

High-throughput

0.437

High

426207

RS19A
Small ribosomal subunit protein eS19A

1

1

High-throughput

0.437

High

471317

RS22A
Small ribosomal subunit protein uS8A

1

1

High-throughput

0.437

High

480378

RS6A
Small ribosomal subunit protein eS6A

1

1

High-throughput

0.437

High

480947

RS8A
Small ribosomal subunit protein eS8A

1

1

High-throughput

0.437

High

606783

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

1

High-throughput

0.437

High

645713

RS7A
Small ribosomal subunit protein eS7A

1

2

High-throughput

0.437

High

663660

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

700682

RSSA1
Small ribosomal subunit protein uS2A

1

2

High-throughput

0.437

High

706557

RS3A1
Small ribosomal subunit protein eS1A

1

2

High-throughput

0.437

High

775899

DSN1
Kinetochore-associated protein DSN1

1

1

High-throughput

0.437

High

863653

COPA
Coatomer subunit alpha

1

2

Small-scale

0.437

High

902137

H3
Histone H3

1

1

High-throughput

0.437

High

978048

RUVB1
RuvB-like protein 1

1

2

High-throughput

0.437

High

986651

SEC10
Exocyst complex component SEC10

1

1

Small-scale

0.437

High

987069

TFC6
Transcription factor tau 91 kDa subunit

1

1

High-throughput

0.437

High

987738

URN1
Pre-mRNA-splicing factor URN1

1

1

High-throughput

0.437

High

996351

RS10A
Small ribosomal subunit protein eS10A

1

1

High-throughput

0.437

High

629079

SCJ1
DnaJ-related protein SCJ1

1

0

High-throughput

0.426

High

812342

DPH4
Diphthamide biosynthesis protein 4

1

0

High-throughput

0.426

High

997076

FLC1
Flavin carrier protein 1

2

0

High-throughput

0.319

High

860417

EIF2A
Eukaryotic translation initiation factor 2A

1

0

High-throughput

0.282

High

864471

ARPC2
Actin-related protein 2/3 complex subunit 2

1

0

High-throughput

0.282

High

586452

PRP6
Pre-mRNA-splicing factor 6

1

0

High-throughput

0.279

Low

866348

APP1
Phosphatidate phosphatase APP1

1

0

High-throughput

0.279

Low

615197

BUR1
Serine/threonine-protein kinase BUR1

1

0

High-throughput

0.269

Low

707526

PMT1
Dolichyl-phosphate-mannose--protein mannosyltransferase 1

1

0

High-throughput

0.269

Low

746887

SLT11
Pre-mRNA-splicing factor SLT11

1

0

High-throughput

0.269

Low

764019

SAW1
Single-strand annealing weakened protein 1

1

0

High-throughput

0.269

Low

792464

GZF3
Protein GZF3

1

0

High-throughput

0.269

Low

968097

PRS8
26S proteasome regulatory subunit 8 homolog

1

0

High-throughput

0.269

Low

768070

NSA2
Ribosome biogenesis protein NSA2

1

0

High-throughput

0.265

Low

976055

PRP3
U4/U6 small nuclear ribonucleoprotein PRP3

1

0

High-throughput

0.265

Low

1014996

MLH3
DNA mismatch repair protein MLH3

1

0

High-throughput

0.265

Low

996182

ESA1
Histone acetyltransferase ESA1

1

0

Small-scale

0.261

Low

767606

NU157
Nucleoporin NUP157

1

0

High-throughput

0.249

Low

784365

COPB
Coatomer subunit beta

1

0

Small-scale

0.249

Low

812162

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.249

Low

977648

NUP53
Nucleoporin NUP53

1

0

High-throughput

0.249

Low

986283

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.249

Low

969292

UBC7
Ubiquitin-conjugating enzyme E2 7

1

0

High-throughput

0.238

Low


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Last updated: 15 Jul 2024