Protein: PNO1
Pre-rRNA-processing protein PNO1 (Partner of NOB1) (Ribosomal RNA-processing protein 20)

Gene: PNO1
Organism: Saccharomyces cerevisiae S288C
Interactions: 106
UniProt ID: Q99216

Gene Ontology (top 5):
GO:0000447 - endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000472 - endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005730 - nucleolus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

770083

RIO2
Serine/threonine-protein kinase RIO2

13

3

Small-scale

0.757

High

748762

ENP1
Essential nuclear protein 1

11

1

Small-scale

0.754

High

995644

NOB1
20S-pre-rRNA D-site endonuclease NOB1

7

2

Small-scale

0.739

High

413800

RS14A
Small ribosomal subunit protein uS11A

2

1

Small-scale

0.737

High

991204

TSR1
Ribosome biogenesis protein TSR1

6

2

Small-scale

0.729

High

634855

KRR1
KRR1 small subunit processome component

2

0

High-throughput

0.716

High

635681

PWP2
Periodic tryptophan protein 2

4

1

Small-scale

0.697

High

987715

NOC4
Nucleolar complex protein 4

6

0

Small-scale

0.690

High

1015300

RIO1
Serine/threonine-protein kinase RIO1

4

3

Small-scale

0.676

High

979103

DHR1
Probable ATP-dependent RNA helicase DHR1

5

0

Small-scale

0.672

High

979760

UTP14
U3 small nucleolar RNA-associated protein 14

3

2

High-throughput

0.661

High

973706

UTP17
NET1-associated nuclear protein 1

3

3

High-throughput

0.656

High

784547

DIM1
Dimethyladenosine transferase

4

0

Small-scale

0.644

High

860785

UTP22
U3 small nucleolar RNA-associated protein 22

3

0

High-throughput

0.634

High

709396

LTV1
Protein LTV1

4

0

Small-scale

0.631

High

860545

SLX9
Ribosome biogenesis protein SLX9

3

0

Small-scale

0.623

High

706581

RS3A1
Small ribosomal subunit protein eS1A

1

1

High-throughput

0.618

High

997096

KEL3
Kelch repeat-containing protein 3

2

0

High-throughput

0.587

High

756820

UTP9
U3 small nucleolar RNA-associated protein 9

2

0

High-throughput

0.585

High

772710

UTP18
U3 small nucleolar RNA-associated protein 18

2

0

High-throughput

0.585

High

775415

FAF1
Protein FAF1

2

0

Small-scale

0.585

High

988666

UTP4
U3 small nucleolar RNA-associated protein 4

2

1

Small-scale

0.584

High

1015687

NOP58
Nucleolar protein 58

2

1

High-throughput

0.584

High

866095

NAT10
RNA cytidine acetyltransferase

2

0

High-throughput

0.559

High

1015145

RRP6
Exosome complex exonuclease RRP6

2

0

Small-scale

0.559

High

1015746

RRP12
Ribosomal RNA-processing protein 12

2

0

Small-scale

0.559

High

676511

XPO1
Exportin-1

1

1

High-throughput

0.536

High

976904

HAS1
ATP-dependent RNA helicase HAS1

1

0

High-throughput

0.513

High

743088

GBLP
Small ribosomal subunit protein RACK1

1

1

High-throughput

0.479

High

978665

UTP5
U3 small nucleolar RNA-associated protein 5

1

1

High-throughput

0.479

High

985451

UTP13
U3 small nucleolar RNA-associated protein 13

1

2

High-throughput

0.479

High

985845

UTP21
U3 small nucleolar RNA-associated protein 21

1

2

High-throughput

0.479

High

997074

BMS1
Ribosome biogenesis protein BMS1

1

2

High-throughput

0.479

High

1015339

UTP12
U3 small nucleolar RNA-associated protein 12

1

2

High-throughput

0.479

High

1015632

NOP56
Nucleolar protein 56

1

1

High-throughput

0.479

High

1015701

CMR1
DNA damage-binding protein CMR1

1

1

High-throughput

0.479

High

141608

RS9A
Small ribosomal subunit protein uS4A

1

0

High-throughput

0.458

High

383437

RL25
Large ribosomal subunit protein uL23

1

0

High-throughput

0.458

High

407432

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

426235

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.458

High

480404

RS6A
Small ribosomal subunit protein eS6A

1

0

High-throughput

0.458

High

480970

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.458

High

558352

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.458

High

606795

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

0

High-throughput

0.458

High

628638

SIS1
Protein SIS1

1

0

High-throughput

0.458

High

630571

RRP7
Ribosomal RNA-processing protein 7

1

0

High-throughput

0.458

High

632178

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.458

High

663806

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

688514

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

700717

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.458

High

707169

DCA13
Protein SOF1

1

0

High-throughput

0.458

High

711099

UTP11
U3 small nucleolar RNA-associated protein 11

1

0

High-throughput

0.458

High

716017

UTP20
U3 small nucleolar RNA-associated protein 20

1

0

High-throughput

0.458

High

752755

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.458

High

755224

LRP1
Exosome complex protein LRP1

1

0

High-throughput

0.458

High

767453

UTP7
U3 small nucleolar RNA-associated protein 7

1

0

High-throughput

0.458

High

774303

RRT14
Regulator of rDNA transcription protein 14

1

0

High-throughput

0.458

High

792654

UTP10
U3 small nucleolar RNA-associated protein 10

1

0

High-throughput

0.458

High

799886

ROK1
ATP-dependent RNA helicase ROK1

1

0

High-throughput

0.458

High

810964

MTR4
ATP-dependent RNA helicase DOB1

1

0

High-throughput

0.458

High

811589

MPP10
U3 small nucleolar RNA-associated protein MPP10

1

0

High-throughput

0.458

High

816934

NOL10
Ribosome biogenesis protein ENP2

1

0

High-throughput

0.458

High

820262

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

860833

RRP46
Exosome complex component RRP46

1

0

Small-scale

0.458

High

861063

UTP8
U3 small nucleolar RNA-associated protein 8

1

0

High-throughput

0.458

High

864758

ESF2
Pre-rRNA-processing protein ESF2

1

0

High-throughput

0.458

High

865445

CSL4
Exosome complex component CSL4

1

0

High-throughput

0.458

High

866300

NOP15
Ribosome biogenesis protein 15

1

0

High-throughput

0.458

High

866599

APJ1
J domain-containing protein APJ1

1

0

High-throughput

0.458

High

866646

IMP4
U3 small nucleolar ribonucleoprotein protein IMP4

1

0

High-throughput

0.458

High

902170

H3
Histone H3

1

0

High-throughput

0.458

High

967853

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

970498

UTP6
U3 small nucleolar RNA-associated protein 6

1

0

High-throughput

0.458

High

977727

GIS1
Transcriptional activator/repressor GIS1

1

0

High-throughput

0.458

High

979273

UTP15
U3 small nucleolar RNA-associated protein 15

1

0

High-throughput

0.458

High

982934

RRP5
rRNA biogenesis protein RRP5

1

0

High-throughput

0.458

High

983793

FCF1
rRNA-processing protein FCF1

1

0

High-throughput

0.458

High

984333

RRP45
Exosome complex component RRP45

1

0

Small-scale

0.458

High

986306

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.458

High

986779

NEP1
Ribosomal RNA small subunit methyltransferase NEP1

1

0

High-throughput

0.458

High

987086

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.458

High

987628

RRP9
Ribosomal RNA-processing protein 9

1

0

High-throughput

0.458

High

988499

BFR2
Protein BFR2

1

0

High-throughput

0.458

High

993384

RCL1
RNA 3'-terminal phosphate cyclase-like protein

1

0

High-throughput

0.458

High

995866

SGO1
Shugoshin

1

0

High-throughput

0.458

High

995885

UTP16
U3 small nucleolar RNA-associated protein 16

1

0

High-throughput

0.458

High

996374

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.458

High

1014913

FCF2
rRNA-processing protein FCF2

1

0

High-throughput

0.458

High

1015096

SAS10
Something about silencing protein 10

1

0

High-throughput

0.458

High

1015186

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

1108006

EFG1P
rRNA-processing protein EFG1

1

0

High-throughput

0.458

High

1303345

NOP14
Nucleolar complex protein 14

1

0

High-throughput

0.458

High

664578

HRR25
Casein kinase I homolog HRR25

1

1

Small-scale

0.445

High

755957

YHS2
MIP18 family protein YHR122W

1

0

High-throughput

0.438

High

479849

RS4A
Small ribosomal subunit protein eS4A

1

0

Small-scale

0.426

High

681125

HS104
Heat shock protein 104

1

0

High-throughput

0.426

High

734002

RPF2
Ribosome biogenesis protein RPF2

1

0

High-throughput

0.426

High

769924

SSB2
Ribosome-associated molecular chaperone SSB2

1

0

High-throughput

0.426

High

965092

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

0

High-throughput

0.426

High

971929

NU116
Nucleoporin NUP116/NSP116

1

0

Small-scale

0.426

High

471342

RS22A
Small ribosomal subunit protein uS8A

2

0

High-throughput

0.305

High

987372

CORO
Coronin-like protein

1

0

High-throughput

0.269

Low

358341

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.249

Low

745969

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

762715

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

860434

EIF2A
Eukaryotic translation initiation factor 2A

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024