Protein: VAV3
Guanine nucleotide exchange factor VAV3 (VAV-3)

Gene: VAV3
Organism: Homo sapiens
Interactions: 53
UniProt ID: Q9UKW4

Gene Ontology (top 5):
GO:0001525 - angiogenesis
GO:0001772 - immunological synapse
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005096 - GTPase activator activity
GO:0005154 - epidermal growth factor receptor binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

924938

GRB2
Growth factor receptor-bound protein 2

7

20

Small-scale

0.968

High

339121

EGFR
Epidermal growth factor receptor

6

20

Small-scale

0.931

High

384022

ERBB2
Receptor tyrosine-protein kinase erbB-2

2

20

High-throughput

0.778

High

602023

ERBB3
Receptor tyrosine-protein kinase erbB-3

2

20

High-throughput

0.778

High

901037

RHOA
Transforming protein RhoA

2

20

Small-scale

0.778

High

441580

MET
Hepatocyte growth factor receptor

1

20

High-throughput

0.692

High

499291

KIT
Mast/stem cell growth factor receptor Kit

1

20

High-throughput

0.692

High

1035413

GAB1
GRB2-associated-binding protein 1

1

20

High-throughput

0.692

High

925718

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

Small-scale

0.647

High

951449

RHOG
Rho-related GTP-binding protein RhoG

1

20

Small-scale

0.647

High

1071026

ERBB4
Receptor tyrosine-protein kinase erbB-4

1

20

High-throughput

0.647

High

411523

INSR
Insulin receptor

1

20

Small-scale

0.618

High

435801

IGF1R
Insulin-like growth factor 1 receptor

1

20

Small-scale

0.618

High

445884

ROS1
Proto-oncogene tyrosine-protein kinase ROS

1

20

Small-scale

0.618

High

452495

PGFRB
Platelet-derived growth factor receptor beta

1

20

Small-scale

0.618

High

655500

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

20

Small-scale

0.618

High

666186

SHC1
SHC-transforming protein 1

1

20

Small-scale

0.618

High

1028447

M3K1
Mitogen-activated protein kinase kinase kinase 1

1

10

High-throughput

0.618

High

1172216

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.618

High

1261030

BLNK
B-cell linker protein

1

20

Small-scale

0.618

High

1027629

CBLB
E3 ubiquitin-protein ligase CBL-B

2

20

High-throughput

0.606

High

1354815

ZRAN1
Ubiquitin thioesterase ZRANB1

2

5

High-throughput

0.606

High

1156538

RINT1
RAD50-interacting protein 1

2

0

High-throughput

0.580

High

994689

DDR1
Epithelial discoidin domain-containing receptor 1

1

20

Small-scale

0.575

High

1356638

ALK
ALK tyrosine kinase receptor

1

20

Small-scale

0.575

High

709107

MCM7
DNA replication licensing factor MCM7

2

7

High-throughput

0.571

High

924433

RL40
Ubiquitin-ribosomal protein eL40 fusion protein

2

4

High-throughput

0.571

High

1164899

FIP1
Pre-mRNA 3'-end-processing factor FIP1

2

1

High-throughput

0.571

High

1356639

NOP58
Nucleolar protein 58

2

3

High-throughput

0.571

High

940679

3BP2
SH3 domain-binding protein 2

1

12

Small-scale

0.553

High

487829

ANDR
Androgen receptor

1

19

High-throughput

0.536

High

370679

ESR1
Estrogen receptor

1

20

Small-scale

0.527

High

1356640

LC7L2
Putative RNA-binding protein Luc7-like 2

2

2

High-throughput

0.521

High

199011

RFOX2
RNA binding protein fox-1 homolog 2

1

10

High-throughput

0.479

High

236848

CCNT1
Cyclin-T1

1

2

High-throughput

0.479

High

990738

CKAP4
Cytoskeleton-associated protein 4

1

20

High-throughput

0.479

High

1023836

TRAF1
TNF receptor-associated factor 1

1

4

Small-scale

0.479

High

1024785

TRAF3
TNF receptor-associated factor 3

1

12

Small-scale

0.479

High

1042817

CUL3
Cullin-3

1

8

High-throughput

0.479

High

1124964

ZN326
DBIRD complex subunit ZNF326

1

1

High-throughput

0.479

High

1204707

DDX42
ATP-dependent RNA helicase DDX42

1

5

High-throughput

0.479

High

1263578

PSPC1
Paraspeckle component 1

1

12

High-throughput

0.479

High

1356641

TRAF6
TNF receptor-associated factor 6

1

12

Small-scale

0.479

High

1356642

TNR11
Tumor necrosis factor receptor superfamily member 11A

1

5

Small-scale

0.479

High

342586

CAH2
Carbonic anhydrase 2

1

0

High-throughput

0.458

High

1332959

AAMDC
Mth938 domain-containing protein

1

0

High-throughput

0.458

High

736093

ATPG
ATP synthase subunit gamma, mitochondrial

1

2

High-throughput

0.437

High

839703

SERPH
Serpin H1

1

7

High-throughput

0.437

High

1026007

TADBP
TAR DNA-binding protein 43

1

15

High-throughput

0.437

High

1302717

RBM15
RNA-binding protein 15

1

14

High-throughput

0.437

High

1301878

CLCC1
Chloride channel CLIC-like protein 1

2

0

High-throughput

0.298

High

534154

T2FB
General transcription factor IIF subunit 2

1

0

High-throughput

0.249

Low

1126317

FA76B
Protein FAM76B

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024